PCYT1A

General Information

Gene Name       : PCYT1A
Gene ID             : ENSG00000161217.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PCYT1A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PCYT1AENSG00000161217.1130.9943.7937.39ENCSR000AEF
HepG2PCYT1AENSG00000161217.1138.5033.3435.92ENCSR985KAT
K562PCYT1AENSG00000161217.1142.0342.2242.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PCYT1A is not avaliable on ENCORE database.



Proteins bound to RNA
  • PCYT1A RNA is bound by 17 proteins.  







eCLIP assay for PCYT1A is not avaliable on ENCORE database.





17 proteins are bound to PCYT1A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3195968472195968532-3'-UTR,CDS,intron-Distal,intron-Proximal,polyA_site4.323596.01372K562AQR
chr3195974312195974394-3'-UTR,CDS,intron-Distal,intron-Proximal3.473014.51027K562BUD13
chr3195964331195964417-3'-UTR,intron-Distal3.965983.09815K562IGF2BP1
chr3195974334195974399-3'-UTR,CDS,intron-Distal,intron-Proximal4.334644.16554HepG2PPIG
chr3195974308195974397-3'-UTR,CDS,intron-Distal,intron-Proximal4.117853.81597K562RBM15
chr3195974290195974393-3'-UTR,CDS,intron-Distal,intron-Proximal4.523385.59408HepG2GRWD1
chr3195963159195963220-3'-UTR,intron-Distal4.548233.69433K562UPF1
chr3195963558195963627-3'-UTR,intron-Distal4.6932520.86532K562LIN28B
chr3195975068195975164-3'-UTR,CDS,intron-Distal,intron-Proximal3.636815.10069HepG2GRWD1
chr3195974397195974506-3'-UTR,CDS,intron-Distal,intron-Proximal4.433924.82934K562RBM15
chr3196014436196014534-5'-UTR,intron-Distal4.135578.78209HepG2PRPF8
chr3196014313196014451-5'-UTR,intron-Distal3.550815.32227K562EFTUD2
chr3195966410195966476-CDS,intron-Distal,intron-Proximal4.543455.18660HepG2PPIG
chr3195966454195966569-CDS,intron-Distal4.991345.37137HepG2BCLAF1
chr3195966419195966547-CDS,intron-Distal,intron-Proximal3.179987.64415K562ZNF622
chr3195984717195984760-3'-UTR,CDS,intron-Distal,intron-Proximal4.030313.12746HepG2GRWD1
chr3195984716195984760-3'-UTR,CDS,intron-Distal,intron-Proximal5.439288.80307K562UCHL5
chr3195997282195997316-3'-UTR,CDS,intron-Distal,intron-Proximal3.860483.86058K562GRWD1
chr3195984725195984759-3'-UTR,CDS,intron-Distal,intron-Proximal3.319616.36421K562ZNF622
chr3195966417195966453-CDS,intron-Distal,intron-Proximal3.428104.22563K562UCHL5
chr3195968803195968819-CDS,intron-Distal,intron-Proximal4.9455611.65116K562AQR
chr3195997282195997331-3'-UTR,CDS,intron-Distal,intron-Proximal4.165283.31827HepG2GRWD1
chr3195969396195969443-CDS,intron-Distal,intron-Proximal3.707605.35619K562AQR
chr3195966453195966525-CDS,intron-Distal4.850856.44794K562UCHL5
chr3195966417195966536-CDS,intron-Distal,intron-Proximal3.463793.77784K562RBM15
chr3195997283195997323-3'-UTR,CDS,intron-Distal,intron-Proximal3.564438.43531K562ZNF622
chr3195984724195984760-3'-UTR,CDS,intron-Distal,intron-Proximal3.568109.05563HepG2PPIG
chr3195968749195968820-CDS,intron-Distal,intron-Proximal3.085914.07440K562PRPF8
chr3195968769195968803-CDS,intron-Distal,intron-Proximal4.6647412.35151K562AQR
chr3195997265195997393-3'-UTR,CDS,intron-Distal,intron-Proximal3.402276.20035HepG2BCLAF1
chr3195997284195997328-3'-UTR,CDS,intron-Distal,intron-Proximal3.446628.45427K562UCHL5
chr3195977966195978014-intron-Distal6.041238.47410K562DROSHA
chr3196013340196013454-intron-Distal3.272074.52210K562KHSRP
chr3195978836195979001-intron-Distal3.583677.66248K562DROSHA
chr3195978868195978989-intron-Distal3.128503.51708K562RBFOX2
chr3195944424195944541-intron-Distal4.003714.19039HepG2PTBP1
chr3195978014195978068-intron-Distal6.225848.47410K562DROSHA
chr3195966620195966670-intron-Distal,intron-Proximal3.247314.23709HepG2AQR
chr3195977778195977826-intron-Distal4.922713.62726K562DROSHA
chr3195978893195979054-intron-Distal3.993345.78025HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PCYT1A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PCYT1A is not available on ENCORE database.

  • 90 RBPs can affect the levels of PCYT1A.  








The Knockdown/knockout RNA-Seq assay for PCYT1A is not available on ENCORE database.





90 RBPs can affect the gene expression of PCYT1A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PCYT1AENSG00000161217.7597.58630806.13170-0.431903.035901.99430HepG2ADAR
PCYT1AENSG00000161217.71081.32800802.219400.430603.116802.28300HepG2ASCC1
PCYT1AENSG00000161217.71836.457901370.267700.422404.830203.96430HepG2AUH
PCYT1AENSG00000161217.71631.409801197.870100.445504.358503.62740HepG2BOP1
PCYT1AENSG00000161217.71190.97680762.156000.643906.511805.36040HepG2CIRBP
PCYT1AENSG00000161217.7694.966601099.70430-0.662107.065006.00570HepG2CPSF6
PCYT1AENSG00000161217.71956.633801210.769600.6923016.2348014.93160HepG2CELF1
PCYT1AENSG00000161217.71082.423001301.78530-0.266203.083902.30750HepG2DAZAP1
PCYT1AENSG00000161217.71138.40710776.554200.551805.670504.73540HepG2DDX21
PCYT1AENSG00000161217.71172.08800928.776700.335602.056801.50860HepG2DDX3X
PCYT1AENSG00000161217.71406.429501021.095600.461803.362802.52050HepG2DDX55
PCYT1AENSG00000161217.71137.37860911.973400.318503.306002.57490HepG2DKC1
PCYT1AENSG00000161217.7604.54300804.59430-0.412404.972304.13770HepG2DNAJC2
PCYT1AENSG00000161217.7794.64150606.236500.390302.400001.55340HepG2EIF3D
PCYT1AENSG00000161217.71541.85890847.665900.8630010.019308.82090HepG2EIF4A3
PCYT1AENSG00000161217.71549.831801284.368000.271003.065402.19260HepG2EIF4G1
PCYT1AENSG00000161217.7965.803601230.32860-0.349202.433901.66740HepG2EIF4G2
PCYT1AENSG00000161217.71519.93860931.418500.706409.150007.65320HepG2EWSR1
PCYT1AENSG00000161217.71597.911201110.301600.525104.206003.27240HepG2FIP1L1
PCYT1AENSG00000161217.7478.09050849.92900-0.830107.987806.00610HepG2FKBP4
PCYT1AENSG00000161217.7617.336501101.60120-0.835503.657602.48410HepG2FTO
PCYT1AENSG00000161217.71242.00490909.193200.449902.483401.42390HepG2FUS
PCYT1AENSG00000161217.71076.74910855.086300.332402.012101.41860HepG2FXR1
PCYT1AENSG00000161217.71095.966201375.25690-0.327503.986103.14110HepG2HNRNPF
PCYT1AENSG00000161217.7858.934901185.79970-0.465207.331606.28080HepG2HNRNPL
PCYT1AENSG00000161217.71119.63420766.110100.547306.177404.83130HepG2HNRNPM
PCYT1AENSG00000161217.7705.31500905.52120-0.360503.875503.16850HepG2HNRNPU
PCYT1AENSG00000161217.71530.200401102.551700.472803.148401.82700HepG2HSPD1
PCYT1AENSG00000161217.71137.042101354.23180-0.252201.967001.34830HepG2IGF2BP1
PCYT1AENSG00000161217.71442.64800806.413600.8390010.845009.60130HepG2IGF2BP2
PCYT1AENSG00000161217.71109.88940811.053800.452402.673101.69020HepG2KHSRP
PCYT1AENSG00000161217.71520.90300855.384100.8302010.339209.09610HepG2MAGOH
PCYT1AENSG00000161217.71408.11180860.199700.710905.478304.61530HepG2MATR3
PCYT1AENSG00000161217.7894.17330634.478900.494902.499201.49610HepG2METAP2
PCYT1AENSG00000161217.71215.66120880.485100.465303.425302.72420HepG2NCBP2
PCYT1AENSG00000161217.71092.54290784.234500.478203.667002.84330HepG2PABPC4
PCYT1AENSG00000161217.71220.36130749.456600.7033013.7703012.58070HepG2PCBP1
PCYT1AENSG00000161217.7548.09560807.64980-0.559306.669105.56300HepG2PPIL4
PCYT1AENSG00000161217.71390.72980762.594300.8668020.7424019.51130HepG2PTBP1
PCYT1AENSG00000161217.71511.545301308.123400.208402.628802.04740HepG2PUM1
PCYT1AENSG00000161217.71442.70440970.926500.5712011.5313010.42160HepG2PUS1
PCYT1AENSG00000161217.71203.01570825.920800.542506.887905.96760HepG2QKI
PCYT1AENSG00000161217.71495.42700830.676600.848105.807404.81080HepG2RAVER1
PCYT1AENSG00000161217.71902.710501314.993700.532908.849008.04330HepG2RBM22
PCYT1AENSG00000161217.71155.96030749.571600.624907.698806.62260HepG2RBM25
PCYT1AENSG00000161217.7982.33020710.842400.466602.743501.68770HepG2RCC2
PCYT1AENSG00000161217.71153.14510848.699100.442105.394604.67920HepG2NELFE
PCYT1AENSG00000161217.7956.06630790.439100.274402.296101.72810HepG2RECQL
PCYT1AENSG00000161217.7828.03310589.900200.489104.326703.57450HepG2RPS19
PCYT1AENSG00000161217.71082.55260807.323600.423103.152902.29800HepG2RPS2
PCYT1AENSG00000161217.7661.96030806.39750-0.284702.504101.88590HepG2SAFB2
PCYT1AENSG00000161217.7778.69310592.048200.395202.625601.71080HepG2SERBP1
PCYT1AENSG00000161217.71191.95400793.969500.586109.340308.35240HepG2SF3B4
PCYT1AENSG00000161217.71199.68390940.380200.351204.888304.07290HepG2SMN1
PCYT1AENSG00000161217.71943.017401485.209300.387506.621505.93870HepG2SRFBP1
PCYT1AENSG00000161217.71642.70040828.728000.9870028.8713027.69960HepG2SRSF1
PCYT1AENSG00000161217.71616.027601216.708300.409406.421205.52170HepG2SRSF5
PCYT1AENSG00000161217.71083.516301351.15720-0.318503.694502.90810HepG2SRSF7
PCYT1AENSG00000161217.71090.36000674.210700.6934013.3572012.30680HepG2SRSF9
PCYT1AENSG00000161217.71688.983601289.464800.389305.981205.28200HepG2SSB
PCYT1AENSG00000161217.71982.914601383.702800.519007.245406.31920HepG2SUCLG1
PCYT1AENSG00000161217.71063.92480744.881300.514206.467605.67290HepG2TAF15
PCYT1AENSG00000161217.7933.38030684.456900.447404.247003.21970HepG2TIA1
PCYT1AENSG00000161217.71324.83990879.824600.590408.354907.57130HepG2TIAL1
PCYT1AENSG00000161217.71282.064301068.902700.262202.665102.07740HepG2UTP3
PCYT1AENSG00000161217.71003.77550842.503200.252602.405901.77370HepG2ZC3H8
PCYT1AENSG00000161217.72028.981801217.645000.7366025.2890024.05470HepG2ZNF622
PCYT1AENSG00000161217.71675.359201252.518500.419504.148302.66670K562AARS
PCYT1AENSG00000161217.71816.275902605.67250-0.520706.137204.32140K562ABCF1
PCYT1AENSG00000161217.71457.633102250.32340-0.6265014.9256013.71650K562AGGF1
PCYT1AENSG00000161217.71685.453002341.56890-0.474305.359104.43350K562AKAP8L
PCYT1AENSG00000161217.72021.684902456.87980-0.281303.081802.11510K562ATP5C1
PCYT1AENSG00000161217.71757.686001356.940800.373202.987202.07900K562BOP1
PCYT1AENSG00000161217.71986.573102459.37380-0.308004.524503.71820K562DDX47
PCYT1AENSG00000161217.72085.568102519.66160-0.272803.171202.22510K562DKC1
PCYT1AENSG00000161217.72428.600102035.486500.254702.964702.22440K562EIF2S2
PCYT1AENSG00000161217.71815.505701305.815800.475307.614006.67580K562FXR1
PCYT1AENSG00000161217.7873.397301380.08340-0.660006.945304.68880K562GEMIN5
PCYT1AENSG00000161217.71792.644501377.569500.379903.596502.69540K562GPKOW
PCYT1AENSG00000161217.72219.234802712.55390-0.289602.637501.89870K562GRSF1
PCYT1AENSG00000161217.71360.439801692.73000-0.315302.884301.78850K562HNRNPA1
PCYT1AENSG00000161217.71760.274701370.354300.361203.489102.82930K562HNRNPC
PCYT1AENSG00000161217.71741.444702222.50560-0.351903.563402.34370K562HNRNPL
PCYT1AENSG00000161217.71369.576901874.56500-0.452806.508105.12750K562HNRNPU
PCYT1AENSG00000161217.71918.142102484.97070-0.373503.350702.43330K562KIF1C
PCYT1AENSG00000161217.71560.057701859.82150-0.253603.102802.24870K562MTPAP
PCYT1AENSG00000161217.71425.572401951.24210-0.452902.963302.04590K562NAA15
PCYT1AENSG00000161217.71595.708401253.873300.347703.468302.07900K562NCBP2
PCYT1AENSG00000161217.71147.918501500.67300-0.386603.516202.41600K562PCBP2
PCYT1AENSG00000161217.71643.074102126.26120-0.371903.231502.33310K562PPIG
PCYT1AENSG00000161217.71997.449101638.606000.285602.607901.96030K562PTBP1
PCYT1AENSG00000161217.71449.696102322.15490-0.679709.400708.44900K562PUS1
PCYT1AENSG00000161217.71653.393102262.62240-0.452606.727305.82910K562RBM15
PCYT1AENSG00000161217.7952.365701369.56770-0.524103.510501.99680K562RRP9
PCYT1AENSG00000161217.7982.428701337.68320-0.445303.918301.93310K562SRP68
PCYT1AENSG00000161217.72466.844502089.069500.239703.615002.56140K562SRPK2
PCYT1AENSG00000161217.71039.654901351.63060-0.378604.543102.84610K562SSB
PCYT1AENSG00000161217.71878.443001529.677300.296202.838402.00690K562SYNCRIP
PCYT1AENSG00000161217.7894.927601211.48360-0.436904.676703.63870K562U2AF2
PCYT1AENSG00000161217.72401.155202902.56830-0.273602.314601.53680K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PCYT1A is not available on ENCORE database.





18 RBPs can affect the splicing of PCYT1A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPCYT1AENSG00000161217.7chr3-1959742371959745141959742371959743891959750771959751940.117000.000070.00974longerK562AGGF1
A3SSPCYT1AENSG00000161217.7chr3-1959742371959745141959742371959743891959750771959751940.126000.000070.03646longerK562HNRNPU
A3SSPCYT1AENSG00000161217.7chr3-1959742371959745141959742371959743891959750771959751940.197000.000050.07814longerHepG2SLTM
A3SSPCYT1AENSG00000161217.7chr3-1959688181959690211959688181959689611959694321959695470.066000.000160.00132longerK562AQR
A3SSPCYT1AENSG00000161217.7chr3-1959742371959745141959742371959743891959750771959751940.188000.000000.00000longerK562AQR
A3SSPCYT1AENSG00000161217.7chr3-1959742371959745141959742371959743891959750771959751940.131000.000000.00039longerK562PUS1
RIPCYT1AENSG00000161217.7chr3-195974237195975194195974237195974389195975077195975194-0.162000.000930.05358excludedK562DROSHA
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.165000.000000.00000includedK562PUS1
RIPCYT1AENSG00000161217.7chr3-195974237195975194195974237195974389195975077195975194-0.064000.000090.01146excludedK562EIF4G2
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.130000.000350.03387includedK562HNRNPU
RIPCYT1AENSG00000161217.7chr3-195974237195975194195974237195974389195975077195975194-0.096000.000030.00167excludedK562SRSF1
RIPCYT1AENSG00000161217.7chr3-195974237195975194195974237195974389195975077195975194-0.105000.001080.08773excludedK562UCHL5
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.184000.000000.00000includedK562AGGF1
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.262000.001120.02826includedHepG2FTO
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.099000.000170.00234includedK562AKAP8L
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.087000.000450.00656includedK562RBM15
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.145000.006010.06713includedK562U2AF2
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.101000.004550.04733includedHepG2NCBP2
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.112000.008350.07729includedK562UTP18
RIPCYT1AENSG00000161217.7chr3-195974237195975194195974237195974389195975077195975194-0.064000.000140.02373excludedK562PUM1
RIPCYT1AENSG00000161217.7chr3-1959742371959751941959742371959743891959750771959751940.205000.000000.00000includedK562AQR
RIPCYT1AENSG00000161217.7chr3-195974237195975194195974237195974389195975077195975194-0.095000.000020.00099excludedK562PTBP1
MXEPCYT1AENSG00000161217.7chr3-195984658195984758195997285195997412195975077195975194196014485196014534-0.146000.000240.010942includedK562RBM15
MXEPCYT1AENSG00000161217.7chr3-1959846581959847581959972851959974421959750771959751941960144021960145970.076000.000100.001181includedK562AQR
MXEPCYT1AENSG00000161217.7chr3-1959846581959847581959972851959974121959750771959751941960144021960145970.106000.008820.057221includedK562AQR
MXEPCYT1AENSG00000161217.7chr3-195984658195984758195997285195997412195975077195975194196014485196014561-0.175000.001200.065982includedHepG2TBRG4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PCYT1A is not avaliable on ENCORE database.