MDM4

General Information

Gene Name       : MDM4
Gene ID             : ENSG00000198625.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MDM4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MDM4ENSG00000198625.128.628.428.52ENCSR000AEF
HepG2MDM4ENSG00000198625.125.926.356.13ENCSR985KAT
K562MDM4ENSG00000198625.127.256.747.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MDM4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MDM4 RNA is bound by 28 proteins.  







eCLIP assay for MDM4 is not avaliable on ENCORE database.





28 proteins are bound to MDM4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1204515957204516007+3'-UTR,CDS,intron-Distal,intron-Proximal3.166607.15216K562BUD13
chr1204518310204518450+3'-UTR,CDS,intron-Distal,intron-Proximal4.2691019.43067HepG2BCLAF1
chr1204518889204518954+3'-UTR,intron-Distal4.053743.74511K562IGF2BP1
chr1204518405204518493+3'-UTR,CDS,intron-Distal3.522309.31995K562UCHL5
chr1204515927204516006+3'-UTR,CDS,intron-Distal,intron-Proximal3.171888.25677K562ZNF622
chr1204523815204523860+3'-UTR,intron-Distal4.204804.31871HepG2HNRNPM
chr1204518682204518769+3'-UTR,CDS,intron-Distal3.484028.50351HepG2BCLAF1
chr1204521694204521741+3'-UTR,intron-Distal3.149113.57155HepG2ILF3
chr1204515974204516005+3'-UTR,CDS,intron-Distal3.115238.71292HepG2BCLAF1
chr1204518497204518549+3'-UTR,CDS,intron-Distal3.233006.26015K562RBM15
chr1204515964204515987+3'-UTR,CDS,intron-Distal3.204373.70975K562UCHL5
chr1204511924204512071+3'-UTR,CDS,intron-Distal3.6781525.96285K562ZNF622
chr1204513743204513805+3'-UTR,CDS,intron-Distal4.2878610.24470HepG2BCLAF1
chr1204518339204518405+3'-UTR,CDS,intron-Distal,intron-Proximal3.405065.89284K562RBM15
chr1204520744204520860+3'-UTR,intron-Distal4.039333.65854HepG2RBFOX2
chr1204520855204520931+3'-UTR,intron-Distal3.2545010.65171K562ILF3
chr1204511994204512075+3'-UTR,CDS,intron-Distal,intron-Proximal3.6404218.49416HepG2BCLAF1
chr1204525565204525617+3'-UTR,intron-Distal4.135513.30425K562LIN28B
chr1204513662204513743+3'-UTR,CDS,intron-Distal,intron-Proximal4.1401811.64153HepG2BCLAF1
chr1204512052204512073+3'-UTR,CDS,intron-Distal,intron-Proximal3.785224.06757K562UCHL5
chr1204522634204522703+3'-UTR,intron-Distal3.410684.83226HepG2HNRNPM
chr1204523195204523279+3'-UTR,intron-Distal3.655905.73852HepG2FUBP3
chr1204518812204518819+3'-UTR,intron-Distal4.319363.71570HepG2BCLAF1
chr1204511924204512052+3'-UTR,CDS,intron-Distal3.0926614.08027K562UCHL5
chr1204518676204518773+3'-UTR,CDS,intron-Distal4.0034414.57929K562RBM15
chr1204523130204523194+3'-UTR,intron-Distal3.195667.33493K562KHSRP
chr1204511917204511994+3'-UTR,CDS,intron-Distal4.4577817.55697HepG2BCLAF1
chr1204513661204513697+3'-UTR,CDS,intron-Distal,intron-Proximal3.856375.80935K562ZNF622
chr1204527065204527137+3'-UTR,intron-Distal4.773539.03043K562ZC3H11A
chr1204513742204513812+3'-UTR,CDS,intron-Distal4.004505.74136K562DDX24
chr1204523680204523800+3'-UTR,intron-Distal3.513833.46578HepG2ZC3H11A
chr1204515921204515974+3'-UTR,CDS,intron-Distal,intron-Proximal3.300627.74581HepG2BCLAF1
chr1204518302204518338+3'-UTR,CDS,intron-Distal,intron-Proximal3.893705.71420K562RBM15
chr1204525374204525446+3'-UTR,intron-Distal3.171126.66758K562ILF3
chr1204520751204520808+3'-UTR,intron-Distal3.190414.18745K562RBFOX2
chr1204501866204501964+3'-UTR,CDS,intron-Distal,intron-Proximal3.209774.64228HepG2KHSRP
chr1204522296204522355+3'-UTR,intron-Distal3.582486.49618K562HNRNPC
chr1204485556204485660+5'-UTR,intron-Proximal4.857247.07015K562SRSF1
chr1204494657204494725+CDS,intron-Proximal3.130114.23325HepG2BCLAF1
chr1204499827204499948+CDS,intron-Distal,intron-Proximal3.580299.12797HepG2PPIG
chr1204499728204499821+CDS,intron-Distal,intron-Proximal3.916834.36528HepG2U2AF2
chr1204501344204501417+CDS,intron-Distal,intron-Proximal6.8007710.09256HepG2PRPF8
chr1204495511204495558+CDS,intron-Distal3.530754.71060K562BUD13
chr1204499884204499951+CDS,intron-Distal,intron-Proximal3.329536.94506K562DDX24
chr1204495506204495558+CDS,intron-Distal3.554317.59700K562ZNF622
chr1204506540204506610+CDS,intron-Distal,intron-Proximal4.028459.29427K562U2AF2
chr1204501317204501388+CDS,intron-Distal,intron-Proximal3.4335213.50876HepG2BCLAF1
chr1204501317204501348+CDS,intron-Distal,intron-Proximal4.741286.56507HepG2GRWD1
chr1204495483204495559+CDS,intron-Distal,intron-Proximal5.418469.44903HepG2PPIG
chr1204499923204499946+CDS,intron-Distal,intron-Proximal3.807985.35682HepG2GRWD1
chr1204499759204499840+CDS,intron-Distal,intron-Proximal3.976687.33504K562SF3B4
chr1204506538204506612+CDS,intron-Distal,intron-Proximal3.343667.39078HepG2U2AF2
chr1204499886204499950+CDS,intron-Distal,intron-Proximal3.029564.36338K562SRSF1
chr1204501317204501345+CDS,intron-Distal,intron-Proximal3.100896.00907HepG2PPIG
chr1204507294204507317+intron-Distal,intron-Proximal4.637954.69223K562SF3B4
chr1204502671204502729+intron-Distal4.124143.61897HepG2HNRNPC
chr1204506686204506722+intron-Distal,intron-Proximal4.180399.09095K562TIA1
chr1204485746204485884+intron-Distal3.996414.40053K562GTF2F1
chr1204499966204500046+intron-Distal,intron-Proximal4.809494.44893K562RBM22
chr1204501391204501480+intron-Distal,intron-Proximal3.102004.12972HepG2TIAL1
chr1204501785204501866+intron-Distal,intron-Proximal3.331499.83419K562KHSRP
chr1204506650204506707+intron-Distal,intron-Proximal4.8652014.93315HepG2TIAL1
chr1204512104204512170+intron-Distal,intron-Proximal5.527678.70072K562RBM22
chr1204499655204499788+intron-Distal,intron-Proximal4.153423.24603K562KHSRP
chr1204507286204507294+intron-Distal,intron-Proximal5.265363.91589K562SF3B4
chr1204507196204507273+intron-Distal,intron-Proximal4.600349.51639K562TARDBP
chr1204506879204506946+intron-Distal4.8502314.00109K562TARDBP
chr1204513500204513569+intron-Distal,intron-Proximal3.749743.24603K562KHSRP
chr1204493984204494126+intron-Distal3.064343.54602K562TIA1
chr1204485758204485854+intron-Distal4.280925.11005HepG2PRPF4
chr1204485746204485885+intron-Distal3.457734.70430K562CSTF2T
chr1204499733204499796+intron-Distal,intron-Proximal4.062054.33574K562U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MDM4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MDM4 is not available on ENCORE database.

  • 91 RBPs can affect the levels of MDM4.  








The Knockdown/knockout RNA-Seq assay for MDM4 is not available on ENCORE database.





91 RBPs can affect the gene expression of MDM4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MDM4ENSG00000198625.8724.138001059.14530-0.548603.847903.23560HepG2AKAP1
MDM4ENSG00000198625.8720.942501011.79050-0.489006.619105.48510HepG2AKAP8L
MDM4ENSG00000198625.8445.53330876.37140-0.9760011.427709.91360HepG2ASCC1
MDM4ENSG00000198625.8444.92410609.16480-0.453303.031502.40800HepG2BOP1
MDM4ENSG00000198625.8771.783701226.37540-0.6681011.6606010.51630HepG2CELF1
MDM4ENSG00000198625.81048.106801318.64160-0.331304.547903.63340HepG2DAZAP1
MDM4ENSG00000198625.8538.34490751.98900-0.482203.763102.98350HepG2DDX21
MDM4ENSG00000198625.8485.996601014.61890-1.0619013.7192012.43230HepG2DDX3X
MDM4ENSG00000198625.8538.06910681.82080-0.341602.663401.97020HepG2DNAJC21
MDM4ENSG00000198625.8527.21470675.81960-0.358203.476302.75960HepG2DNAJC2
MDM4ENSG00000198625.81158.75200837.872400.467703.578902.90890HepG2EIF2S1
MDM4ENSG00000198625.81276.35250925.990300.462903.375802.67140HepG2EIF4A3
MDM4ENSG00000198625.82120.759701565.550200.437808.074407.14030HepG2ETF1
MDM4ENSG00000198625.8866.878601233.67690-0.509103.730301.79990HepG2FMR1
MDM4ENSG00000198625.8669.14850449.359500.574405.128304.06830HepG2FUBP3
MDM4ENSG00000198625.81336.87950919.955000.539104.997503.79190HepG2G3BP2
MDM4ENSG00000198625.8374.15680509.26420-0.444802.525901.67470HepG2GEMIN5
MDM4ENSG00000198625.8594.50010776.67160-0.385602.207301.30250HepG2GNB2L1
MDM4ENSG00000198625.8383.38460688.35310-0.844408.946207.88210HepG2HNRNPA1
MDM4ENSG00000198625.81235.05380877.387300.493204.443303.57440HepG2HNRNPK
MDM4ENSG00000198625.8956.867901201.17760-0.328104.287403.46210HepG2HNRNPL
MDM4ENSG00000198625.8826.90250604.965500.450803.093902.43270HepG2HNRNPLL
MDM4ENSG00000198625.8513.51370760.60940-0.566807.540306.57800HepG2HNRNPU
MDM4ENSG00000198625.8619.61890776.93620-0.326403.486902.67190HepG2ILF2
MDM4ENSG00000198625.81276.24440886.029300.526403.548802.39520HepG2KHSRP
MDM4ENSG00000198625.8685.48160939.73280-0.455102.845602.20640HepG2MATR3
MDM4ENSG00000198625.8517.59900697.21820-0.429803.167802.30490HepG2MSI2
MDM4ENSG00000198625.81201.31370856.700700.487603.868603.02540HepG2PABPC4
MDM4ENSG00000198625.81036.65740837.091900.308403.039702.23420HepG2PRPF4
MDM4ENSG00000198625.8903.036001248.18690-0.467004.653103.90280HepG2PUF60
MDM4ENSG00000198625.8810.904901325.00960-0.7084017.7905016.55450HepG2PUM1
MDM4ENSG00000198625.8788.380201324.03920-0.7480012.3275010.97190HepG2PUM2
MDM4ENSG00000198625.8629.999601025.69880-0.7032013.5783012.39090HepG2PUS1
MDM4ENSG00000198625.81608.67390932.141300.7872015.8201014.50460HepG2QKI
MDM4ENSG00000198625.81561.440001308.518100.254802.355801.86780HepG2RBM22
MDM4ENSG00000198625.81696.23200846.030801.0035021.3911019.62440HepG2RBM25
MDM4ENSG00000198625.81308.90140892.296000.552709.453108.41520HepG2RECQL
MDM4ENSG00000198625.8384.38450556.49300-0.533803.971803.24820HepG2RPS19
MDM4ENSG00000198625.8613.76190846.13130-0.463203.208802.34650HepG2RPS2
MDM4ENSG00000198625.8857.535601138.70770-0.409102.236001.51690HepG2RPS3A
MDM4ENSG00000198625.8636.91880863.69000-0.439403.032901.90650HepG2RPS5
MDM4ENSG00000198625.81557.567201137.165900.453802.521601.87840HepG2SF3A3
MDM4ENSG00000198625.81141.05610896.099200.348503.993703.30500HepG2SF3B4
MDM4ENSG00000198625.8921.742301196.82520-0.376805.154804.24530HepG2SLBP
MDM4ENSG00000198625.8493.74950789.90100-0.6779011.105709.95290HepG2SMN1
MDM4ENSG00000198625.81803.280501477.936900.286903.895403.33100HepG2SRFBP1
MDM4ENSG00000198625.8748.12580935.38140-0.322302.768102.29500HepG2SRSF1
MDM4ENSG00000198625.8876.61080644.326500.444002.518001.56650HepG2SRSF3
MDM4ENSG00000198625.81444.45580761.023900.9244027.2416025.84550HepG2SRSF9
MDM4ENSG00000198625.8785.829501401.58280-0.8348021.8071020.33130HepG2SUCLG1
MDM4ENSG00000198625.81558.11030840.890300.8897021.2746019.92520HepG2TAF15
MDM4ENSG00000198625.81388.65690772.522500.845907.554906.18940HepG2TIA1
MDM4ENSG00000198625.8506.36080745.68250-0.558406.941706.11840HepG2TRIM56
MDM4ENSG00000198625.8937.008401219.43250-0.380103.388402.41150HepG2TUFM
MDM4ENSG00000198625.8674.618101008.48970-0.580109.355008.20210HepG2UPF1
MDM4ENSG00000198625.8742.83140973.66120-0.390404.296003.57570HepG2UTP3
MDM4ENSG00000198625.8668.782401050.19860-0.651104.548303.20410HepG2XRCC6
MDM4ENSG00000198625.81162.13670826.094800.492308.146207.09600HepG2ZC3H8
MDM4ENSG00000198625.8782.951701109.14930-0.502508.734607.90280HepG2ZNF622
MDM4ENSG00000198625.81766.732302251.61520-0.349905.529704.77040K562AGGF1
MDM4ENSG00000198625.81000.626901271.38300-0.345504.005902.15260K562AKAP1
MDM4ENSG00000198625.81680.604602342.88010-0.479305.665704.71160K562AKAP8L
MDM4ENSG00000198625.84130.051501930.841601.0968026.0914024.48710K562AQR
MDM4ENSG00000198625.82003.610102458.19310-0.295003.559302.51060K562ATP5C1
MDM4ENSG00000198625.8779.251101009.36830-0.373302.157301.30780K562BCLAF1
MDM4ENSG00000198625.8837.878701082.21800-0.369203.537801.80060K562CEBPZ
MDM4ENSG00000198625.81257.456601806.72590-0.522904.433502.54030K562CKAP4
MDM4ENSG00000198625.81194.713301720.78070-0.526405.474003.87770K562CPEB4
MDM4ENSG00000198625.8472.69540759.60390-0.684307.571406.26880K562CPSF6
MDM4ENSG00000198625.8495.49080765.75590-0.628006.807905.04300K562CSTF2
MDM4ENSG00000198625.8909.822701243.91260-0.451206.051104.22120K562DDX21
MDM4ENSG00000198625.8849.997201288.12880-0.599702.861801.80140K562DDX3X
MDM4ENSG00000198625.82353.595301345.719400.8064013.9166012.00330K562EIF4A3
MDM4ENSG00000198625.8751.668301040.34710-0.468904.698402.99900K562EXOSC5
MDM4ENSG00000198625.8968.316101328.29940-0.456004.272703.20250K562FIP1L1
MDM4ENSG00000198625.82004.065301534.237900.385302.319201.67980K562G3BP2
MDM4ENSG00000198625.8557.47460725.21140-0.379502.564801.79860K562GPKOW
MDM4ENSG00000198625.8957.933301749.94290-0.8693015.2595013.44650K562GRSF1
MDM4ENSG00000198625.81188.93130828.323100.521305.733804.90530K562HNRNPC
MDM4ENSG00000198625.8566.63910739.54940-0.384202.623101.51380K562HNRNPF
MDM4ENSG00000198625.81089.682801609.43340-0.562607.341205.53900K562HNRNPL
MDM4ENSG00000198625.8697.115901092.55280-0.648205.829204.41160K562HNRNPM
MDM4ENSG00000198625.8881.678101179.94140-0.420404.743803.56600K562HNRNPU
MDM4ENSG00000198625.81352.564001813.23010-0.422902.879801.82810K562IGF2BP2
MDM4ENSG00000198625.81452.039601844.57070-0.345203.035501.77190K562IGF2BP3
MDM4ENSG00000198625.81945.635302486.47810-0.353902.936902.08370K562KIF1C
MDM4ENSG00000198625.8530.41370707.89710-0.416403.071402.14600K562METAP2
MDM4ENSG00000198625.8916.248501340.85720-0.549307.479206.20700K562MTPAP
MDM4ENSG00000198625.8992.431101489.67390-0.586008.726807.50370K562NSUN2
MDM4ENSG00000198625.82473.857701696.258300.544307.276805.66140K562PCBP2
MDM4ENSG00000198625.81534.567101167.567300.394203.028601.39650K562PKM
MDM4ENSG00000198625.8931.781101507.89360-0.694508.975107.28530K562PPIG
MDM4ENSG00000198625.8921.80430742.638300.311702.078501.30500K562PSIP1
MDM4ENSG00000198625.83153.129902547.219700.307803.616902.38750K562PUM1
MDM4ENSG00000198625.81458.181002323.69190-0.672209.290808.34560K562PUS1
MDM4ENSG00000198625.81402.174902263.92390-0.6912014.7830013.39720K562RBM15
MDM4ENSG00000198625.82046.548701595.960000.358702.828901.96400K562SF3B4
MDM4ENSG00000198625.81088.540501815.54310-0.738008.987807.72220K562SRSF1
MDM4ENSG00000198625.8767.416901110.13920-0.532707.829305.86730K562SRSF7
MDM4ENSG00000198625.81486.353201837.60970-0.306102.049301.43430K562TARDBP
MDM4ENSG00000198625.81976.160101487.875100.409303.093901.92750K562U2AF1
MDM4ENSG00000198625.82306.167501536.422100.5858010.077208.54200K562U2AF2
MDM4ENSG00000198625.81212.644401579.54380-0.381403.907103.06560K562UPF1
MDM4ENSG00000198625.81088.796401351.54780-0.311902.520801.68260K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MDM4 is not available on ENCORE database.





16 RBPs can affect the splicing of MDM4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMDM4ENSG00000198625.8chr1+204513662204513812204511911204512072204515924204515960-0.513000.000000.00000excludedHepG2U2AF1
SEMDM4ENSG00000198625.8chr1+204506557204506625204501318204501374204507336204507436-0.344000.002310.04100excludedHepG2U2AF1
SEMDM4ENSG00000198625.8chr1+204513662204513812204511911204512072204515924204515960-0.128000.000730.02443excludedK562AKAP8L
SEMDM4ENSG00000198625.8chr1+2045065572045066252045013182045013742045073362045074360.346000.000000.00000includedK562PUM1
SEMDM4ENSG00000198625.8chr1+204513662204513812204511911204512072204515924204515960-0.342000.000050.00116excludedHepG2U2AF2
SEMDM4ENSG00000198625.8chr1+204506557204506625204501318204501374204507336204507436-0.332000.000230.00406excludedHepG2U2AF2
SEMDM4ENSG00000198625.8chr1+2045065572045066252045013182045013742045073362045074360.200000.005690.06859includedK562PUS1
SEMDM4ENSG00000198625.8chr1+2044972222044973572044954872044955622044998112044999450.103000.000880.01539includedK562PUS1
SEMDM4ENSG00000198625.8chr1+204501318204501374204499811204499945204507336204507436-0.182000.000960.01644excludedK562PUS1
SEMDM4ENSG00000198625.8chr1+204506557204506625204501318204501374204507336204507436-0.371000.001190.05134excludedHepG2SFPQ
SEMDM4ENSG00000198625.8chr1+204513662204513812204511911204512072204515924204515960-0.219000.000280.00791excludedK562U2AF1
SEMDM4ENSG00000198625.8chr1+204506557204506625204501318204501374204507336204507436-0.492000.000840.08670excludedHepG2PCBP2
SEMDM4ENSG00000198625.8chr1+2045065572045066252045013182045013742045073362045074360.296000.000000.00366includedK562PUM2
SEMDM4ENSG00000198625.8chr1+2045065572045066252045013182045013742045073362045074360.255000.000010.00569includedK562EIF4G2
SEMDM4ENSG00000198625.8chr1+204513662204513812204511911204512072204515924204515960-0.138000.000950.02633excludedK562RBM15
SEMDM4ENSG00000198625.8chr1+204513662204513812204511911204512072204515924204515960-0.125000.000690.02073excludedK562AGGF1
SEMDM4ENSG00000198625.8chr1+2045065572045066252045013182045013742045073362045074360.495000.000170.00998includedK562PTBP1
A3SSMDM4ENSG00000198625.8chr1+2044954622044955622044954872044955622044946172044947240.124000.000840.00592longerK562AQR
A5SSMDM4ENSG00000198625.8chr1+204513662204513812204513662204513797204515924204516005-0.156000.000000.00009shorterK562PUS1
A5SSMDM4ENSG00000198625.8chr1+2044855782044857472044855782044856372044946112044947240.295000.000060.01007longerHepG2RBM22
A5SSMDM4ENSG00000198625.8chr1+204513662204513812204513662204513797204515924204516005-0.118000.000570.05233shorterK562UTP18
A5SSMDM4ENSG00000198625.8chr1+2045136622045138122045136622045137972045159242045159600.123000.000050.01985longerK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MDM4 is not avaliable on ENCORE database.