MAP3K1

General Information

Gene Name       : MAP3K1
Gene ID             : ENSG00000095015.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAP3K1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAP3K1ENSG00000095015.59.528.869.19ENCSR000AEF
HepG2MAP3K1ENSG00000095015.59.6614.8712.27ENCSR985KAT
K562MAP3K1ENSG00000095015.54.845.074.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAP3K1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAP3K1 RNA is bound by 21 proteins.  







eCLIP assay for MAP3K1 is not avaliable on ENCORE database.





21 proteins are bound to MAP3K1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr55619189856191940+3'-UTR4.377323.66896HepG2FUBP3
chr55619157756191651+3'-UTR4.8307610.24889HepG2FUBP3
chr55619170856191774+3'-UTR3.158793.98039HepG2FUBP3
chr55619158156191678+3'-UTR5.023839.34312K562PUM2
chr55618181356181883+CDS4.5209211.51775K562YBX3
chr55617087156170941+CDS4.165306.23296HepG2BCLAF1
chr55617795756178020+CDS3.174865.25426HepG2PCBP2
chr55618063156180653+CDS3.704304.76554HepG2BCLAF1
chr55616063056160758+CDS4.059433.35081HepG2G3BP1
chr55618175556181792+CDS,intron-Proximal4.630114.78529HepG2BCLAF1
chr55617928556179420+CDS,intron-Proximal4.460659.33787HepG2AQR
chr55615095456151063+intron-Distal5.024605.43236K562PTBP1
chr55614527856145334+intron-Distal4.584774.94096HepG2SFPQ
chr55615093856151057+intron-Distal5.4959421.72233HepG2PTBP1
chr55611231956112417+intron-Distal3.738155.79195K562CSTF2T
chr55611283656112918+intron-Distal4.419649.20848HepG2HNRNPM
chr55611228456112408+intron-Distal3.614217.73643HepG2GTF2F1
chr55613195356131986+intron-Distal4.526145.37406HepG2HNRNPM
chr55614427056144355+intron-Distal4.778226.79824HepG2HNRNPM
chr55611400756114110+intron-Distal5.189467.61259K562KHSRP
chr55615115756151329+intron-Distal3.637655.98773K562KHSRP
chr55611276756112836+intron-Distal3.877987.91672HepG2HNRNPM
chr55613217356132217+intron-Distal4.955196.95924HepG2HNRNPM
chr55613689056136921+intron-Distal4.852774.95918HepG2ILF3
chr55611232056112386+intron-Distal4.007023.01456K562EXOSC5
chr55611279656112845+intron-Distal3.080764.41495HepG2XPO5
chr55613240056132473+intron-Distal4.260973.53404K562HNRNPM
chr55611229056112409+intron-Distal4.4269710.81740HepG2PRPF4
chr55611231556112424+intron-Distal3.299105.52498HepG2CSTF2T
chr55615347656153536+intron-Distal3.817733.27714HepG2HNRNPL
chr55614736256147466+intron-Distal5.6784911.59253HepG2PTBP1
chr55613692156136951+intron-Distal3.896504.53895HepG2ILF3
chr55615096056151095+intron-Distal3.911568.27362HepG2PCBP2
chr55613080656130902+intron-Distal4.229354.24441HepG2ILF3
chr55611233256112429+intron-Distal3.672595.08363HepG2KHSRP
chr55611233156112418+intron-Distal3.311488.88662HepG2NKRF
chr55614457056144662+intron-Distal3.609103.02234K562KHSRP
chr55613239856132472+intron-Distal6.3486420.33004HepG2HNRNPM
chr55611231156112378+intron-Distal3.428945.19200HepG2PCBP2
chr55611854856118607+intron-Distal3.154353.69184HepG2SUGP2
chr55614103256141133+intron-Distal3.092615.01720HepG2QKI
chr55613135956131463+intron-Distal3.732963.26022HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAP3K1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAP3K1 is not available on ENCORE database.

  • 85 RBPs can affect the levels of MAP3K1.  








The Knockdown/knockout RNA-Seq assay for MAP3K1 is not available on ENCORE database.





85 RBPs can affect the gene expression of MAP3K1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAP3K1ENSG00000095015.5862.719301208.19900-0.485903.303802.17210HepG2AKAP8
MAP3K1ENSG00000095015.51002.614901377.10950-0.457903.649002.74970HepG2ASCC1
MAP3K1ENSG00000095015.5508.07970992.87890-0.966604.147103.00310HepG2BCCIP
MAP3K1ENSG00000095015.5746.424201193.42990-0.677008.076707.11750HepG2BOP1
MAP3K1ENSG00000095015.5900.879601245.08350-0.466805.337804.31040HepG2CALR
MAP3K1ENSG00000095015.51377.011101841.10340-0.419002.615001.67070HepG2CCAR1
MAP3K1ENSG00000095015.51071.032401356.25220-0.340604.890704.05400HepG2CKAP4
MAP3K1ENSG00000095015.5824.408201095.61590-0.410303.155302.42590HepG2CPSF6
MAP3K1ENSG00000095015.5852.687701157.96030-0.441504.226502.87610HepG2CPSF7
MAP3K1ENSG00000095015.5784.518701025.78340-0.386804.099702.85620HepG2YBX3
MAP3K1ENSG00000095015.5790.15720613.506400.365002.643901.58950HepG2CSTF2
MAP3K1ENSG00000095015.51226.678101451.58890-0.242903.052402.28010HepG2DAZAP1
MAP3K1ENSG00000095015.51083.553901594.32940-0.557205.115004.28770HepG2DDX3X
MAP3K1ENSG00000095015.5574.89790976.12900-0.763803.313402.47770HepG2DDX55
MAP3K1ENSG00000095015.51836.771301244.158200.561902.811201.82580HepG2DDX59
MAP3K1ENSG00000095015.5969.107301296.58320-0.420003.500802.37090HepG2DDX5
MAP3K1ENSG00000095015.5771.050901007.26620-0.385503.987103.15590HepG2DNAJC21
MAP3K1ENSG00000095015.5662.34250998.33710-0.5919010.667209.48460HepG2DNAJC2
MAP3K1ENSG00000095015.5608.63420890.24510-0.548604.026302.68470HepG2EFTUD2
MAP3K1ENSG00000095015.51018.815701316.59450-0.369902.458301.89800HepG2EIF2S1
MAP3K1ENSG00000095015.5874.476801455.01250-0.734507.261906.22720HepG2EIF4A3
MAP3K1ENSG00000095015.51396.150402237.03010-0.6801017.6184016.31590HepG2ETF1
MAP3K1ENSG00000095015.5929.470501325.58520-0.512105.821304.60820HepG2EWSR1
MAP3K1ENSG00000095015.5593.044801097.53080-0.888004.054902.82360HepG2FTO
MAP3K1ENSG00000095015.51031.589901467.98360-0.509004.536803.66610HepG2FXR1
MAP3K1ENSG00000095015.5886.028501361.80320-0.620105.711104.76930HepG2G3BP1
MAP3K1ENSG00000095015.5883.557501241.91730-0.491203.736503.00140HepG2GPKOW
MAP3K1ENSG00000095015.51049.078201295.10000-0.303903.477102.39110HepG2HDGF
MAP3K1ENSG00000095015.51028.681801333.99790-0.375004.854303.67160HepG2HNRNPA2B1
MAP3K1ENSG00000095015.5630.359901131.11930-0.8435011.4870010.15630HepG2HNRNPC
MAP3K1ENSG00000095015.51124.090401378.87170-0.294701.953701.36000HepG2HNRNPK
MAP3K1ENSG00000095015.51091.096501322.32030-0.277303.590902.82910HepG2HNRNPL
MAP3K1ENSG00000095015.5814.450701185.18890-0.541204.819904.01280HepG2HNRNPLL
MAP3K1ENSG00000095015.5779.63160979.63470-0.329502.556801.64150HepG2HNRNPM
MAP3K1ENSG00000095015.5655.777801123.64180-0.7769016.5145015.12820HepG2HNRNPU
MAP3K1ENSG00000095015.51120.902001384.25500-0.304401.871801.30650HepG2IGF2BP2
MAP3K1ENSG00000095015.5819.058101147.76490-0.486808.429707.21870HepG2ILF2
MAP3K1ENSG00000095015.5722.775101005.83690-0.476802.593501.32460HepG2ILF3
MAP3K1ENSG00000095015.51482.914101943.58710-0.390302.388901.62120HepG2LARP4
MAP3K1ENSG00000095015.5709.509001146.18240-0.691907.621305.68440HepG2LIN28B
MAP3K1ENSG00000095015.51117.508701476.72510-0.402102.668302.04850HepG2MATR3
MAP3K1ENSG00000095015.5898.722401149.10620-0.354603.002702.16090HepG2MSI2
MAP3K1ENSG00000095015.5825.494601208.84520-0.550303.207102.15790HepG2MTPAP
MAP3K1ENSG00000095015.5841.835301246.92120-0.566803.691502.04180HepG2NKRF
MAP3K1ENSG00000095015.51167.529801439.38660-0.302003.006802.21230HepG2NOL12
MAP3K1ENSG00000095015.5897.426401295.32350-0.529408.941407.95210HepG2PCBP1
MAP3K1ENSG00000095015.5817.301301002.20070-0.294202.561201.84960HepG2PPIL4
MAP3K1ENSG00000095015.5768.947201317.99610-0.7774016.6793015.55370HepG2PTBP1
MAP3K1ENSG00000095015.51013.746801373.98950-0.438704.442803.70810HepG2PUF60
MAP3K1ENSG00000095015.51764.743301458.514100.274903.829103.15580HepG2PUM1
MAP3K1ENSG00000095015.5671.966601381.69600-1.0400032.6738030.98790HepG2PUS1
MAP3K1ENSG00000095015.51905.492901466.839700.377405.288904.57970HepG2NELFE
MAP3K1ENSG00000095015.51025.083701284.95600-0.326002.721602.04220HepG2RPLP0
MAP3K1ENSG00000095015.5676.01560843.41250-0.319201.841201.32990HepG2RPS19
MAP3K1ENSG00000095015.5960.876601213.74340-0.337002.054901.35900HepG2RPS2
MAP3K1ENSG00000095015.5821.671301000.65950-0.284302.858902.20620HepG2SAFB2
MAP3K1ENSG00000095015.5836.712401173.07480-0.487504.399203.52700HepG2SF3B1
MAP3K1ENSG00000095015.51141.977101372.28300-0.265002.794902.20050HepG2SF3B4
MAP3K1ENSG00000095015.51600.687002111.85960-0.399807.109606.40910HepG2SRFBP1
MAP3K1ENSG00000095015.5965.334101171.84540-0.279703.065402.33890HepG2SRSF7
MAP3K1ENSG00000095015.5663.53650901.14640-0.441602.538001.49060HepG2STIP1
MAP3K1ENSG00000095015.5644.26590958.72540-0.573506.309204.92670HepG2SUPT6H
MAP3K1ENSG00000095015.5925.125501155.32150-0.320602.174801.52040HepG2TARDBP
MAP3K1ENSG00000095015.5689.393601091.87110-0.663409.347208.52320HepG2TIAL1
MAP3K1ENSG00000095015.5683.126401101.58540-0.6894013.1803012.08010HepG2TRIM56
MAP3K1ENSG00000095015.51097.006801420.73280-0.373102.467301.68070HepG2UBE2L3
MAP3K1ENSG00000095015.5691.023001394.37640-1.0128030.1820028.38990HepG2UPF1
MAP3K1ENSG00000095015.5499.69910890.22960-0.833102.557301.59530HepG2UPF2
MAP3K1ENSG00000095015.51182.643201433.23910-0.277302.897201.82820HepG2UTP18
MAP3K1ENSG00000095015.51123.088601346.21880-0.261402.625702.04080HepG2UTP3
MAP3K1ENSG00000095015.5594.90240956.66880-0.685402.755402.03130HepG2XRN2
MAP3K1ENSG00000095015.5333.06910497.02250-0.577503.491101.57200K562DDX51
MAP3K1ENSG00000095015.5707.15150562.508600.330002.692401.98090K562EIF2S2
MAP3K1ENSG00000095015.5443.20120595.25570-0.425502.726301.88380K562FIP1L1
MAP3K1ENSG00000095015.5483.82050594.56560-0.297401.933601.41010K562FXR1
MAP3K1ENSG00000095015.5479.80890749.68810-0.643804.016003.10850K562GRSF1
MAP3K1ENSG00000095015.5249.49410451.71530-0.856407.462106.52740K562HNRNPC
MAP3K1ENSG00000095015.51033.29720836.138600.305302.232901.43020K562MBNL1
MAP3K1ENSG00000095015.5635.52380480.422600.403502.186801.44710K562PCBP3
MAP3K1ENSG00000095015.5290.76850441.01130-0.600903.551401.90270K562PHF6
MAP3K1ENSG00000095015.5489.76930368.498400.410302.400801.65650K562POLR2G
MAP3K1ENSG00000095015.5436.63570675.72630-0.630005.552104.32340K562PPIG
MAP3K1ENSG00000095015.5647.25190447.960700.530903.530002.68190K562PRPF8
MAP3K1ENSG00000095015.5350.37100699.48300-0.9974014.7388013.26730K562PTBP1
MAP3K1ENSG00000095015.51441.786501128.863000.352902.783201.96490K562PUF60
MAP3K1ENSG00000095015.51502.081801200.790900.322902.945101.84140K562PUM1
MAP3K1ENSG00000095015.5473.15810697.48680-0.559804.328803.67240K562PUS1
MAP3K1ENSG00000095015.5778.33630632.256100.299802.325001.57150K562SF3A3
MAP3K1ENSG00000095015.5319.36570430.66210-0.431302.338101.38300K562SRSF4
MAP3K1ENSG00000095015.51037.55250781.019900.409702.992601.57280K562SSRP1
MAP3K1ENSG00000095015.5459.81550694.01400-0.593904.990004.02560K562TARDBP
MAP3K1ENSG00000095015.5507.51620669.44800-0.399502.911802.07000K562TIA1
MAP3K1ENSG00000095015.5282.17190413.84200-0.552503.332602.27510K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAP3K1 is not available on ENCORE database.





1 RBPs can affect the splicing of MAP3K1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSMAP3K1ENSG00000095015.5chr5+5617932456179506561793535617950656177396561786930.274000.000000.00002longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAP3K1 is not avaliable on ENCORE database.