L3MBTL1

General Information

Gene Name       : L3MBTL1
Gene ID             : ENSG00000185513.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: L3MBTL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878L3MBTL1ENSG00000185513.162.232.692.46ENCSR000AEF
HepG2L3MBTL1ENSG00000185513.166.496.616.55ENCSR985KAT
K562L3MBTL1ENSG00000185513.162.932.992.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for L3MBTL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • L3MBTL1 RNA is bound by 30 proteins.  







eCLIP assay for L3MBTL1 is not avaliable on ENCORE database.





30 proteins are bound to L3MBTL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr204216298242163030+3'-UTR,CDS3.848783.79347HepG2GRWD1
chr204216338942163494+3'-UTR,CDS,intron-Proximal3.533164.51027K562BUD13
chr204216296842163038+3'-UTR,CDS,intron-Proximal4.9127012.90078HepG2PPIG
chr204216197642162042+3'-UTR,CDS,intron-Proximal4.428505.79396K562DDX24
chr204216292042162950+3'-UTR,CDS,intron-Proximal5.031734.75872K562DDX24
chr204216301142163079+3'-UTR,CDS,intron-Proximal4.1844711.70689HepG2PRPF8
chr204216196642162038+3'-UTR,CDS,intron-Proximal4.028433.67894HepG2AQR
chr204216302742163127+3'-UTR,CDS,intron-Proximal3.754005.42745HepG2BUD13
chr204216267142162734+3'-UTR,CDS,intron-Proximal3.411285.26861K562DDX24
chr204216195842162009+3'-UTR,CDS,intron-Proximal3.901116.80869K562AQR
chr204216340242163474+3'-UTR,CDS,intron-Proximal3.743953.84691HepG2SF3B4
chr204217836142178446+3'-UTR4.398153.34609K562TARDBP
chr204216264742162733+3'-UTR,CDS,intron-Proximal3.296364.74755K562ZNF622
chr204216341042163483+3'-UTR,CDS,intron-Proximal5.1541612.02813K562SF3B4
chr204217877242178848+3'-UTR3.372953.13224HepG2ZC3H11A
chr204214299442143062+5'-UTR,intron-Distal3.630939.29902HepG2PRPF4
chr204214301042143076+5'-UTR,intron-Distal3.646425.03105K562BUD13
chr204216139342161483+5'-UTR,CDS,intron-Distal,intron-Proximal3.9957412.62617HepG2U2AF2
chr204214300342143206+5'-UTR,CDS,intron-Distal,intron-Proximal5.3107322.00513K562DDX24
chr204216156342161614+5'-UTR,CDS,intron-Distal,intron-Proximal5.006343.93614HepG2AQR
chr204214302842143184+5'-UTR,intron-Distal,intron-Proximal4.108383.19943HepG2DROSHA
chr204216148342161550+5'-UTR,CDS,intron-Distal3.954745.74136K562DDX24
chr204216142442161571+5'-UTR,CDS,intron-Distal,intron-Proximal3.8638112.29574HepG2PPIG
chr204214309542143192+5'-UTR,CDS,intron-Distal,intron-Proximal4.8555014.57011HepG2PRPF4
chr204216156242161573+5'-UTR,CDS,intron-Distal,intron-Proximal4.0770710.89879K562AQR
chr204214307642143186+5'-UTR,CDS,intron-Distal,intron-Proximal4.269417.93461K562BUD13
chr204214364542143683+CDS,intron-Proximal3.756736.41974HepG2PPIG
chr204217663642176759+CDS,intron-Distal,intron-Proximal3.8205615.77386HepG2DDX59
chr204216939842169498+CDS,intron-Distal,intron-Proximal3.188557.15529HepG2PPIG
chr204215729442157376+CDS,intron-Proximal3.936845.47804K562ZNF622
chr204214338042143440+CDS,intron-Proximal3.254676.23791HepG2PRPF4
chr204215729642157389+CDS,intron-Proximal4.028519.86697K562DDX24
chr204216509742165110+CDS,intron-Proximal5.761178.34710K562AQR
chr204214376442143802+CDS,intron-Proximal3.731425.58370HepG2PPIG
chr204215729242157355+CDS,intron-Proximal3.825529.04641HepG2PPIG
chr204214477842144819+CDS,intron-Proximal3.000164.96088HepG2GRWD1
chr204214364542143709+CDS,intron-Proximal3.772784.93175HepG2GRWD1
chr204214471742144818+CDS,intron-Proximal4.399847.82678K562ZNF622
chr204216876842168832+CDS,intron-Proximal3.860594.00320K562AQR
chr204214359542143651+CDS,intron-Proximal4.636645.90542HepG2PRPF4
chr204215729242157346+CDS,intron-Proximal4.033785.35703HepG2BCLAF1
chr204214479042144821+CDS,intron-Proximal3.888617.09278HepG2PPIG
chr204214331342143429+CDS,intron-Proximal3.688433.57110HepG2UCHL5
chr204215786442158023+CDS,intron-Distal,intron-Proximal3.563209.25795HepG2GRWD1
chr204214478442144820+CDS,intron-Proximal3.580343.28366HepG2BCLAF1
chr204214334942143420+CDS,intron-Proximal3.864919.51790HepG2PPIG
chr204215902042159144+CDS,intron-Distal,intron-Proximal3.561454.51027K562BUD13
chr204215734642157385+CDS4.761625.37137HepG2BCLAF1
chr204216135342161417+CDS,intron-Distal,intron-Proximal3.515778.53304HepG2SF3A3
chr204217663742176775+CDS,intron-Distal,intron-Proximal6.5855637.17892HepG2PCBP2
chr204215789042157927+CDS,intron-Distal,intron-Proximal5.136024.17466K562DDX24
chr204214347742143542+intron-Distal,intron-Proximal3.198075.62051HepG2PRPF4
chr204217531742175411+intron-Distal6.5703023.07158HepG2QKI
chr204214349842143560+intron-Distal,intron-Proximal3.464414.33898HepG2FAM120A
chr204214352242143595+intron-Distal,intron-Proximal5.174179.50259HepG2EFTUD2
chr204217265242172689+intron-Distal5.9469016.27070HepG2HNRNPM
chr204217656242176634+intron-Distal4.2222212.30245HepG2PCBP2
chr204217653342176662+intron-Distal,intron-Proximal3.5316914.35726HepG2PTBP1
chr204216135042161411+intron-Distal,intron-Proximal3.532805.23533HepG2SF3B4
chr204217657842176665+intron-Distal,intron-Proximal5.260085.16101HepG2PCBP1
chr204217534342175433+intron-Distal6.1518111.89523K562QKI
chr204217658942176747+intron-Distal,intron-Proximal5.1103019.15610HepG2HNRNPK
chr204215908342159238+intron-Distal,intron-Proximal5.012706.48592K562TIA1
chr204217544742175500+intron-Distal4.463748.08894HepG2QKI
chr204215930142159385+intron-Distal,intron-Proximal3.674383.76326HepG2RBFOX2
chr204214347542143550+intron-Distal,intron-Proximal3.084125.96908HepG2RBFOX2
chr204214462242144685+intron-Distal,intron-Proximal3.941833.15006K562RBM15
chr204217663742176682+intron-Distal,intron-Proximal3.445624.21158HepG2CSTF2T
chr204217668242176735+intron-Distal,intron-Proximal3.659444.92762HepG2CSTF2T
chr204214280442142862+intron-Distal3.376693.99908K562BUD13
chr204216157342161625+intron-Distal,intron-Proximal4.8737015.97087K562AQR
chr204217262242172647+intron-Distal4.184903.27946HepG2HNRNPM
chr204214274642142865+intron-Distal,intron-Proximal4.649329.81644HepG2RBFOX2
chr204215781142157879+intron-Distal,intron-Proximal4.594054.62947HepG2AQR
chr204215975542159818+intron-Distal3.588195.09665HepG2HNRNPK
chr204217264142172730+intron-Distal3.182825.59320HepG2SUGP2
chr204215782142157891+intron-Distal,intron-Proximal5.743369.95272K562AQR
chr204216186842161942+intron-Distal,intron-Proximal4.448278.45091HepG2SF3B4
chr204217522042175253+intron-Distal4.253574.05848HepG2QKI
chr204214486242144978+intron-Distal,intron-Proximal4.646905.44904K562TARDBP
chr204215738542157458+intron-Proximal5.961419.95272K562AQR
chr204216511042165140+intron-Proximal5.9966010.48996K562AQR
chr204216306342163123+intron-Proximal4.127683.96990K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for L3MBTL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for L3MBTL1 is not available on ENCORE database.

  • 82 RBPs can affect the levels of L3MBTL1.  








The Knockdown/knockout RNA-Seq assay for L3MBTL1 is not available on ENCORE database.





82 RBPs can affect the gene expression of L3MBTL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
L3MBTL1ENSG00000185513.10346.30810670.11640-0.9524016.8388015.60650HepG2ACO1
L3MBTL1ENSG00000185513.10337.57600515.85080-0.611703.449102.86390HepG2AKAP1
L3MBTL1ENSG00000185513.10507.69320673.25500-0.407203.518102.66530HepG2AKAP8L
L3MBTL1ENSG00000185513.10752.39440514.876000.547203.271302.20560HepG2CCAR1
L3MBTL1ENSG00000185513.10384.48600704.90410-0.874505.783804.67850HepG2CNOT7
L3MBTL1ENSG00000185513.10435.43950203.659001.096207.862406.75280HepG2CPSF6
L3MBTL1ENSG00000185513.10521.65250405.381700.363702.182001.38170HepG2DDX24
L3MBTL1ENSG00000185513.10354.86780494.08510-0.477502.647902.03460HepG2DDX3X
L3MBTL1ENSG00000185513.10566.23230741.32390-0.388702.598501.33940HepG2DDX47
L3MBTL1ENSG00000185513.10813.90710408.009800.9962011.2053010.06010HepG2EIF2S1
L3MBTL1ENSG00000185513.101058.08410868.051500.285501.858101.34470HepG2ETF1
L3MBTL1ENSG00000185513.10377.24560571.25760-0.598602.506501.77010HepG2FIP1L1
L3MBTL1ENSG00000185513.10344.42970204.038800.755302.277801.36410HepG2FTO
L3MBTL1ENSG00000185513.10700.60040308.691201.1823017.2035015.33020HepG2FUBP3
L3MBTL1ENSG00000185513.10751.50860422.040900.832307.780806.69410HepG2G3BP1
L3MBTL1ENSG00000185513.10781.43180448.193800.801907.865706.34810HepG2G3BP2
L3MBTL1ENSG00000185513.10365.01240230.822800.661103.176802.49620HepG2GPKOW
L3MBTL1ENSG00000185513.10570.59860355.390100.683008.206307.05350HepG2HNRNPF
L3MBTL1ENSG00000185513.10626.38260427.610800.550603.895703.07980HepG2HNRNPK
L3MBTL1ENSG00000185513.10270.81640393.97490-0.540802.577601.65820HepG2HNRNPM
L3MBTL1ENSG00000185513.10575.47050458.359900.328202.362301.79890HepG2HNRNPU
L3MBTL1ENSG00000185513.10463.17940349.959900.404302.624901.91900HepG2IGF2BP1
L3MBTL1ENSG00000185513.10563.53550428.956300.393601.975501.39630HepG2IGF2BP2
L3MBTL1ENSG00000185513.10709.06530431.529700.716404.889003.52200HepG2KHSRP
L3MBTL1ENSG00000185513.10336.43990458.13540-0.445402.648701.53880HepG2LARP7
L3MBTL1ENSG00000185513.10365.41260224.747700.701102.166001.31740HepG2MTPAP
L3MBTL1ENSG00000185513.10651.34420468.505700.475302.765102.13250HepG2NCBP2
L3MBTL1ENSG00000185513.10347.11680195.351700.829204.883503.89980HepG2NSUN2
L3MBTL1ENSG00000185513.10393.45280644.26710-0.711503.741502.69700HepG2PABPC1
L3MBTL1ENSG00000185513.10655.98400417.108200.653105.006104.04640HepG2PABPC4
L3MBTL1ENSG00000185513.10343.25150453.70740-0.402502.813501.95840HepG2PARN
L3MBTL1ENSG00000185513.10551.72160389.204300.503304.553303.80770HepG2PCBP1
L3MBTL1ENSG00000185513.10564.11740409.266800.462903.996203.08440HepG2PRPF4
L3MBTL1ENSG00000185513.10480.66950622.11220-0.372102.929902.32360HepG2PUM1
L3MBTL1ENSG00000185513.10489.56680682.55530-0.479405.384704.57670HepG2PUS1
L3MBTL1ENSG00000185513.10669.96020428.921200.643306.514205.61330HepG2QKI
L3MBTL1ENSG00000185513.10312.00560480.99830-0.624502.619001.93240HepG2RAVER1
L3MBTL1ENSG00000185513.10659.93440389.265100.761508.078606.97830HepG2RBM25
L3MBTL1ENSG00000185513.10617.35850440.740300.486104.120803.48370HepG2NELFE
L3MBTL1ENSG00000185513.10699.51520410.473900.769007.832206.87350HepG2RECQL
L3MBTL1ENSG00000185513.10377.74760520.08190-0.461302.838701.74860HepG2RPS5
L3MBTL1ENSG00000185513.10420.34890725.89670-0.788206.415305.36400HepG2SF3A3
L3MBTL1ENSG00000185513.10671.77700412.326200.704108.624007.66970HepG2SF3B4
L3MBTL1ENSG00000185513.10321.27810476.03110-0.567205.552704.69240HepG2SMN1
L3MBTL1ENSG00000185513.101005.67400819.403200.295401.837301.40370HepG2SRFBP1
L3MBTL1ENSG00000185513.10300.53480430.37160-0.518103.764003.23410HepG2SRSF1
L3MBTL1ENSG00000185513.10601.65980349.151700.7850010.828809.60750HepG2SRSF7
L3MBTL1ENSG00000185513.10482.45640350.123600.462403.800003.17520HepG2SRSF9
L3MBTL1ENSG00000185513.10486.33210350.970700.470502.212101.59810HepG2SUPV3L1
L3MBTL1ENSG00000185513.10966.40270386.813501.3209030.9424029.33540HepG2TAF15
L3MBTL1ENSG00000185513.10335.62250214.814300.643603.266302.48540HepG2TARDBP
L3MBTL1ENSG00000185513.10552.50200355.451500.636205.927504.71330HepG2TIA1
L3MBTL1ENSG00000185513.10586.32050445.410900.396502.916502.40570HepG2TIAL1
L3MBTL1ENSG00000185513.10360.82970449.36190-0.316602.000701.50630HepG2TRIM56
L3MBTL1ENSG00000185513.10310.13430488.52150-0.655502.768602.13940HepG2U2AF1
L3MBTL1ENSG00000185513.10343.07920207.327400.726504.664703.67470HepG2UCHL5
L3MBTL1ENSG00000185513.10487.10940321.374900.599902.860401.83860HepG2UPF2
L3MBTL1ENSG00000185513.10422.70110621.52550-0.556205.581704.77960HepG2UTP3
L3MBTL1ENSG00000185513.10520.51290345.492200.591203.576202.76010HepG2XRN2
L3MBTL1ENSG00000185513.10471.94790620.22760-0.394203.087302.49280K562AGGF1
L3MBTL1ENSG00000185513.10407.54270265.338600.619004.459103.07660K562CSTF2
L3MBTL1ENSG00000185513.101074.33620746.414100.525303.358002.28240K562CELF1
L3MBTL1ENSG00000185513.10537.32930403.335300.413703.196701.88780K562DDX21
L3MBTL1ENSG00000185513.10274.29710371.21710-0.436502.494801.50810K562DDX3X
L3MBTL1ENSG00000185513.10272.58280432.20450-0.665006.323505.39610K562DDX47
L3MBTL1ENSG00000185513.10530.59300694.46900-0.388303.244002.28570K562DKC1
L3MBTL1ENSG00000185513.10209.95990291.83660-0.475001.947201.32530K562EIF2S2
L3MBTL1ENSG00000185513.10262.63670387.83520-0.562403.551302.62460K562EIF4A3
L3MBTL1ENSG00000185513.10184.82170256.80850-0.474602.035601.30460K562FIP1L1
L3MBTL1ENSG00000185513.10265.38470403.33310-0.603904.616203.86190K562FXR1
L3MBTL1ENSG00000185513.10621.98140418.761700.570605.190103.73280K562HNRNPA1
L3MBTL1ENSG00000185513.10217.41310365.20790-0.748304.790703.12660K562HNRNPK
L3MBTL1ENSG00000185513.10116.85960211.24020-0.854103.931302.80780K562HNRNPM
L3MBTL1ENSG00000185513.10586.15310463.722300.337902.339801.51810K562HNRNPU
L3MBTL1ENSG00000185513.10210.70580348.16150-0.724504.462003.45700K562HSPD1
L3MBTL1ENSG00000185513.10583.15530767.26530-0.395802.682101.79040K562MBNL1
L3MBTL1ENSG00000185513.10446.27780646.78390-0.535304.203702.81400K562MSI2
L3MBTL1ENSG00000185513.10439.55660333.445000.398502.661801.86820K562MTPAP
L3MBTL1ENSG00000185513.10269.78730387.27000-0.521503.273701.92650K562NCBP2
L3MBTL1ENSG00000185513.10537.80910370.490500.537605.417204.42510K562NSUN2
L3MBTL1ENSG00000185513.10465.10760341.943000.443702.165101.30370K562PCBP2
L3MBTL1ENSG00000185513.10653.76590458.850900.510603.477501.69590K562PKM
L3MBTL1ENSG00000185513.10101.16230262.90290-1.377904.451503.50060K562PRPF8
L3MBTL1ENSG00000185513.10261.96020373.43520-0.511503.350102.62700K562PTBP1
L3MBTL1ENSG00000185513.10438.61710662.06920-0.594004.993003.89900K562PUF60
L3MBTL1ENSG00000185513.10458.98000640.03410-0.479703.220902.64260K562PUS1
L3MBTL1ENSG00000185513.10151.90470267.68820-0.817402.278201.54010K562RPS19
L3MBTL1ENSG00000185513.10372.02660234.131400.668004.383002.75550K562SLBP
L3MBTL1ENSG00000185513.10329.76100239.046000.464002.199601.30580K562SRFBP1
L3MBTL1ENSG00000185513.10662.94470374.538900.8237012.3967010.59940K562SRPK2
L3MBTL1ENSG00000185513.10487.12130359.903800.436603.461302.14110K562SRSF7
L3MBTL1ENSG00000185513.10172.59370285.41950-0.725704.708003.63060K562SYNCRIP
L3MBTL1ENSG00000185513.10427.52090282.415700.598103.853702.70050K562TRIM56
L3MBTL1ENSG00000185513.10388.97700521.58380-0.423202.613601.38450K562TROVE2
L3MBTL1ENSG00000185513.10138.09870249.62230-0.854005.605104.46170K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for L3MBTL1 is not available on ENCORE database.





3 RBPs can affect the splicing of L3MBTL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEL3MBTL1ENSG00000185513.10chr20+4214455842144653421439314214405542144732421448170.362000.000040.00094includedHepG2U2AF2
RIL3MBTL1ENSG00000185513.10chr20+421693924217053442169392421694554216957342170534-0.464000.000570.00856excludedK562AGGF1
MXEL3MBTL1ENSG00000185513.10chr20+42143931421440554214473242144817421436484214379942157296421573850.337000.005040.087871includedK562TARDBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for L3MBTL1 is not avaliable on ENCORE database.