IQSEC2

General Information

Gene Name       : IQSEC2
Gene ID             : ENSG00000124313.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: IQSEC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IQSEC2ENSG00000124313.140.000.050.03ENCSR000AEF
HepG2IQSEC2ENSG00000124313.140.450.310.38ENCSR985KAT
K562IQSEC2ENSG00000124313.1423.7121.0922.40ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IQSEC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • IQSEC2 RNA is bound by 10 proteins.  







eCLIP assay for IQSEC2 is not avaliable on ENCORE database.





10 proteins are bound to IQSEC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX5326342853263514-3'-UTR,CDS,intron-Distal4.763556.20726K562HNRNPK
chrX5326369953263773-3'-UTR,CDS,intron-Distal4.979486.29854K562UPF1
chrX5326345053263526-3'-UTR,CDS,intron-Distal3.045203.52502K562ILF3
chrX5326225853262320-3'-UTR,intron-Distal3.426133.85485K562AKAP1
chrX5326209453262157-3'-UTR,intron-Distal5.6651011.61633K562UPF1
chrX5326225653262313-3'-UTR,intron-Distal3.048235.15194K562UPF1
chrX5326303153263108-3'-UTR,intron-Distal4.489104.75311K562CSTF2T
chrX5326307053263106-3'-UTR,intron-Distal4.261436.36782K562UPF1
chrX5326207253262147-3'-UTR,intron-Distal6.5590310.73721K562PUM2
chrX5326345653263519-3'-UTR,CDS,intron-Distal3.438903.85730K562AKAP1
chrX5326249953262561-3'-UTR,intron-Distal3.725676.55257K562UPF1
chrX5326345553263526-3'-UTR,CDS,intron-Distal5.007674.14061K562DROSHA
chrX5326295853263000-3'-UTR,intron-Distal3.685434.82552K562UPF1
chrX5326382453263971-3'-UTR,CDS,intron-Distal4.795015.62822K562HNRNPK
chrX5330881953308896-CDS,intron-Distal,intron-Proximal4.050083.82619K562ILF3
chrX5327091853270967-CDS,intron-Distal,intron-Proximal5.027314.86944K562AQR
chrX5326565053265724-CDS,intron-Distal,intron-Proximal3.411205.85200K562BUD13
chrX5326564653265728-CDS,intron-Distal,intron-Proximal5.8748823.92744K562AQR
chrX5326725353267317-intron-Distal,intron-Proximal4.7957814.30285K562AQR
chrX5330949653309594-intron-Distal5.662157.91717K562PTBP1
chrX5330925953309371-intron-Distal4.114313.57189K562ILF3
chrX5326731753267327-intron-Distal,intron-Proximal5.2905811.42662K562AQR
chrX5330928153309356-intron-Distal5.100606.95895K562PTBP1
chrX5329552453295614-intron-Distal4.300103.95344K562PUM2
chrX5329730353297465-intron-Distal3.860833.08243K562ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IQSEC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IQSEC2 is not available on ENCORE database.

  • 100 RBPs can affect the levels of IQSEC2.  








The Knockdown/knockout RNA-Seq assay for IQSEC2 is not available on ENCORE database.





100 RBPs can affect the gene expression of IQSEC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IQSEC2ENSG00000124313.841.766404.251403.296205.741805.00750HepG2AKAP1
IQSEC2ENSG00000124313.846.304409.449102.292804.728603.43960HepG2CCAR1
IQSEC2ENSG00000124313.820.961402.405003.123503.336302.21240HepG2GNB2L1
IQSEC2ENSG00000124313.835.1442013.045101.429702.062001.50460HepG2GPKOW
IQSEC2ENSG00000124313.845.346707.517202.592605.651704.53240HepG2MSI2
IQSEC2ENSG00000124313.826.082504.344302.585803.646103.03660HepG2PTBP1
IQSEC2ENSG00000124313.818.767704.984201.912702.021601.47590HepG2PUS1
IQSEC2ENSG00000124313.816.713903.123602.419702.137201.59010HepG2RPS19
IQSEC2ENSG00000124313.8883.21820645.107300.453103.762702.36430K562AARS
IQSEC2ENSG00000124313.8789.431801273.32060-0.689708.269506.18660K562ABCF1
IQSEC2ENSG00000124313.8993.913602631.46370-1.4047019.6376018.24260K562AGGF1
IQSEC2ENSG00000124313.81773.591902891.25290-0.705008.728706.71970K562AKAP8
IQSEC2ENSG00000124313.81175.193402738.07660-1.2203017.8894015.94770K562AKAP8L
IQSEC2ENSG00000124313.8300.512101188.38190-1.9835045.2822043.16270K562AQR
IQSEC2ENSG00000124313.81682.721702872.74900-0.7716010.401408.49560K562ATP5C1
IQSEC2ENSG00000124313.8427.07760833.60400-0.9649011.483109.66630K562BOP1
IQSEC2ENSG00000124313.8574.58730767.52370-0.417703.560901.81640K562CEBPZ
IQSEC2ENSG00000124313.8656.289501321.41770-1.009708.068206.21080K562CNOT7
IQSEC2ENSG00000124313.8643.72230886.38250-0.461504.332103.35190K562CPSF6
IQSEC2ENSG00000124313.8398.25460864.45070-1.1181012.473109.02560K562YBX3
IQSEC2ENSG00000124313.81039.773701759.57050-0.7590013.1348011.10490K562CELF1
IQSEC2ENSG00000124313.8600.56750882.17820-0.554706.799104.86380K562DDX21
IQSEC2ENSG00000124313.8347.37830519.99170-0.582005.854603.93360K562DDX27
IQSEC2ENSG00000124313.8683.201801338.59040-0.970308.515807.45360K562DDX47
IQSEC2ENSG00000124313.82288.419802946.87230-0.364803.200302.24990K562DKC1
IQSEC2ENSG00000124313.8454.88580851.06140-0.9038011.450509.00500K562DNAJC21
IQSEC2ENSG00000124313.83195.36280939.867501.7654097.6891095.01020K562EIF2S2
IQSEC2ENSG00000124313.8483.53750805.02770-0.735404.278803.00200K562EIF3A
IQSEC2ENSG00000124313.8390.82590582.98460-0.576903.458202.28990K562EIF3D
IQSEC2ENSG00000124313.8280.43750396.66520-0.500203.394202.51880K562EIF3G
IQSEC2ENSG00000124313.8426.81790864.04700-1.017506.126703.13600K562EIF4G1
IQSEC2ENSG00000124313.8947.442401431.32780-0.595204.949503.71220K562EIF4G2
IQSEC2ENSG00000124313.8218.92290612.75510-1.4849019.5662016.45890K562FKBP4
IQSEC2ENSG00000124313.8539.49620764.36350-0.502603.511902.47310K562FTO
IQSEC2ENSG00000124313.8248.32700350.67590-0.497903.241101.77990K562FUS
IQSEC2ENSG00000124313.8753.56020475.881200.663004.616703.86230K562FXR1
IQSEC2ENSG00000124313.8329.29350156.909501.069303.983201.41680K562FXR2
IQSEC2ENSG00000124313.886.13820228.91610-1.410109.040007.60930K562G3BP2
IQSEC2ENSG00000124313.8799.118101155.11050-0.531607.068705.29940K562GLRX3
IQSEC2ENSG00000124313.8573.44930846.29500-0.561505.164604.08550K562GPKOW
IQSEC2ENSG00000124313.8456.206801252.30300-1.4568018.1798016.17630K562GRSF1
IQSEC2ENSG00000124313.8545.88260886.66230-0.699808.200806.43370K562HNRNPA1
IQSEC2ENSG00000124313.8898.250101756.79340-0.967805.635303.65760K562HNRNPA2B1
IQSEC2ENSG00000124313.8888.89770705.986400.332302.376701.81740K562HNRNPC
IQSEC2ENSG00000124313.8805.475101209.59920-0.586603.006701.90160K562HNRNPL
IQSEC2ENSG00000124313.8642.51680981.96480-0.611908.313806.77520K562HNRNPU
IQSEC2ENSG00000124313.82089.481901240.933900.7516011.099709.53490K562HSPD1
IQSEC2ENSG00000124313.8750.22910488.180400.619803.321402.16160K562IGF2BP2
IQSEC2ENSG00000124313.8741.614101206.09900-0.701603.980002.24960K562ILF2
IQSEC2ENSG00000124313.8503.79120826.83070-0.714806.713404.41820K562ILF3
IQSEC2ENSG00000124313.8565.01160799.12340-0.500103.902402.13530K562KHDRBS1
IQSEC2ENSG00000124313.81425.392802906.06630-1.027705.277004.06180K562KIF1C
IQSEC2ENSG00000124313.81179.34210683.513300.786807.371504.98030K562LARP7
IQSEC2ENSG00000124313.81032.11500715.928400.527604.409702.47940K562LIN28B
IQSEC2ENSG00000124313.8858.32630629.406200.447403.383901.64620K562LSM11
IQSEC2ENSG00000124313.81936.224302781.59120-0.522702.280501.33430K562MAK16
IQSEC2ENSG00000124313.81922.599003255.48880-0.759808.660806.86670K562MBNL1
IQSEC2ENSG00000124313.8499.91570826.07080-0.724608.124806.57580K562METAP2
IQSEC2ENSG00000124313.81009.867701525.71060-0.595306.253504.57200K562MSI2
IQSEC2ENSG00000124313.8395.855901214.45660-1.6173056.5376053.81340K562MTPAP
IQSEC2ENSG00000124313.8999.609002281.83700-1.1908010.999008.78850K562NAA15
IQSEC2ENSG00000124313.8841.747001349.32270-0.6808016.9889015.34950K562NSUN2
IQSEC2ENSG00000124313.8710.472601269.49520-0.837405.901104.07910K562PABPC1
IQSEC2ENSG00000124313.8840.211201537.33340-0.871604.697503.31290K562PABPN1
IQSEC2ENSG00000124313.8344.758301138.50980-1.7235033.3321030.73470K562PCBP3
IQSEC2ENSG00000124313.8319.25830873.26300-1.4517030.5756028.21810K562POLR2G
IQSEC2ENSG00000124313.81012.77650498.047501.023907.002605.98370K562PTBP1
IQSEC2ENSG00000124313.81125.019301561.73310-0.473204.040603.05940K562PUF60
IQSEC2ENSG00000124313.8914.340601660.81920-0.8611015.8446013.21010K562PUM1
IQSEC2ENSG00000124313.81275.439601627.60980-0.351803.095802.08310K562PUM2
IQSEC2ENSG00000124313.8649.511002715.99770-2.0641033.6732031.75280K562PUS1
IQSEC2ENSG00000124313.8996.478502645.85240-1.4088020.3555018.70050K562RBM15
IQSEC2ENSG00000124313.8746.80060477.311800.645705.497404.26420K562RBM22
IQSEC2ENSG00000124313.8757.06620465.484100.701602.954801.50920K562RBM34
IQSEC2ENSG00000124313.8818.19910577.445200.502704.550403.27610K562RCC2
IQSEC2ENSG00000124313.8272.79110390.65980-0.518104.018302.12640K562RPS10
IQSEC2ENSG00000124313.8238.82080539.72800-1.1763011.7062010.00020K562RPS19
IQSEC2ENSG00000124313.8700.603601178.60940-0.750405.266702.98710K562RPS3A
IQSEC2ENSG00000124313.8667.56370442.422100.593402.352001.43780K562RPS3
IQSEC2ENSG00000124313.8266.35660541.76210-1.024308.087305.87160K562RRP9
IQSEC2ENSG00000124313.81075.12340778.138700.466304.405503.02700K562SAFB
IQSEC2ENSG00000124313.8748.513301406.29730-0.909804.396302.77640K562SF1
IQSEC2ENSG00000124313.8729.301801331.50800-0.8685019.0631017.07770K562SF3A3
IQSEC2ENSG00000124313.8579.73430804.79160-0.473202.995901.98290K562SF3B1
IQSEC2ENSG00000124313.8456.57050871.72840-0.9330012.263109.82870K562SLBP
IQSEC2ENSG00000124313.81906.010101236.423500.624304.366802.14580K562SMN1
IQSEC2ENSG00000124313.8854.53200547.409300.642406.447804.70120K562SRFBP1
IQSEC2ENSG00000124313.81014.008701364.16510-0.427906.865605.46660K562SRPK2
IQSEC2ENSG00000124313.8793.41620426.970000.893808.364306.40590K562SRSF4
IQSEC2ENSG00000124313.8530.66120787.26740-0.569106.982005.11810K562SRSF7
IQSEC2ENSG00000124313.8832.523501200.91660-0.528605.063003.18710K562SSRP1
IQSEC2ENSG00000124313.8979.060601362.65120-0.476905.270103.27040K562SUCLG1
IQSEC2ENSG00000124313.8896.818101931.55650-1.106906.483704.03780K562SUPT6H
IQSEC2ENSG00000124313.81120.34020875.923300.355003.180602.30090K562SYNCRIP
IQSEC2ENSG00000124313.81016.16350494.083301.0402010.571709.03930K562TARDBP
IQSEC2ENSG00000124313.8868.27800476.629000.8652010.346908.64340K562TIA1
IQSEC2ENSG00000124313.8712.06810467.983500.605504.584903.11600K562TRA2A
IQSEC2ENSG00000124313.8144.75240221.79380-0.615602.559901.51390K562U2AF1
IQSEC2ENSG00000124313.8750.040301430.71920-0.9317025.6685023.75500K562UPF1
IQSEC2ENSG00000124313.81032.745602753.15490-1.4146010.266407.34120K562UTP18
IQSEC2ENSG00000124313.8555.320101224.21510-1.1405023.2686020.86730K562WDR3
IQSEC2ENSG00000124313.8854.347301273.08390-0.5754011.001109.44950K562WDR43
IQSEC2ENSG00000124313.81049.084301407.84360-0.424404.366202.73510K562WRN
IQSEC2ENSG00000124313.8461.25800912.61670-0.984403.775001.85280K562XRCC6
IQSEC2ENSG00000124313.8730.169501338.83530-0.8747014.1327012.03860K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IQSEC2 is not available on ENCORE database.





3 RBPs can affect the splicing of IQSEC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEIQSEC2ENSG00000124313.8chrX-533087455330884153295510532962465331067753310796-0.306000.009290.07659excludedK562AQR
SEIQSEC2ENSG00000124313.8chrX-533087455330884153295510532962465331067753310796-0.838000.000700.01678excludedK562U2AF1
SEIQSEC2ENSG00000124313.8chrX-5330874553308841532955105329624653310677533107760.296000.000000.00004includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IQSEC2 is not avaliable on ENCORE database.