FAM50A

General Information

Gene Name       : FAM50A
Gene ID             : ENSG00000071859.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: FAM50A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM50AENSG00000071859.1420.7829.8625.32ENCSR000AEF
HepG2FAM50AENSG00000071859.1439.9424.0231.98ENCSR985KAT
K562FAM50AENSG00000071859.1455.7249.3352.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM50A is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM50A RNA is bound by 22 proteins.  







eCLIP assay for FAM50A is not avaliable on ENCORE database.





22 proteins are bound to FAM50A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX153678820153678892+3'-UTR3.577814.27313HepG2PABPN1
chrX153678771153678814+3'-UTR,CDS,intron-Proximal4.163956.08299HepG2PPIG
chrX153673012153673063+5'-UTR,intron-Distal6.4966534.07433HepG2XPO5
chrX153672927153672982+5'-UTR,intron-Distal6.4764715.64735HepG2XPO5
chrX153672494153672587+5'-UTR,CDS3.881335.58683HepG2GRWD1
chrX153672501153672552+5'-UTR4.171399.85855K562PUM1
chrX153672491153672576+5'-UTR4.417143.72506HepG2PABPN1
chrX153672502153672558+5'-UTR3.6271310.84695K562ZNF800
chrX153672982153673012+5'-UTR,intron-Distal7.7099243.26007HepG2XPO5
chrX153678029153678065+CDS3.3359711.59993K562UCHL5
chrX153677087153677104+CDS3.7906911.97877K562ZNF622
chrX153677982153678048+CDS,intron-Proximal3.150955.91714K562SF3B4
chrX153678596153678649+CDS4.210354.50960HepG2GRWD1
chrX153677072153677105+CDS,intron-Proximal3.2549115.17083K562ZNF800
chrX153677245153677288+CDS3.430556.40565K562DDX24
chrX153674838153674909+CDS,intron-Proximal3.161086.59838K562SRSF1
chrX153678408153678447+CDS4.109744.41267HepG2PPIG
chrX153672637153672689+CDS4.6559915.56361K562UCHL5
chrX153678210153678256+CDS,intron-Proximal3.402244.71371HepG2GRWD1
chrX153677037153677061+CDS,intron-Proximal4.0068115.03868K562ZNF622
chrX153678082153678128+CDS,intron-Proximal6.7784725.32116HepG2AQR
chrX153677099153677103+CDS3.544916.80450K562UCHL5
chrX153674875153674907+CDS4.5704518.30835K562UCHL5
chrX153678031153678051+CDS5.138847.05595K562PUM1
chrX153678184153678272+CDS,intron-Proximal4.7712460.26676K562AQR
chrX153677241153677253+CDS3.643249.75562K562UCHL5
chrX153678162153678252+CDS,intron-Proximal3.825376.15802K562XRN2
chrX153677250153677290+CDS4.4192623.71193K562ZNF622
chrX153676886153676908+CDS4.6983717.61288K562UCHL5
chrX153678560153678581+CDS3.079725.23105K562GRWD1
chrX153674869153674908+CDS3.553339.92158K562TRA2A
chrX153678029153678053+CDS4.435463.49905HepG2PPIG
chrX153674231153674255+CDS5.0475413.49586K562UCHL5
chrX153677261153677300+CDS3.716024.40421K562MTPAP
chrX153678609153678644+CDS4.009894.68902HepG2PPIG
chrX153677061153677087+CDS3.9391319.06254K562ZNF622
chrX153677262153677301+CDS4.359805.18972HepG2GRWD1
chrX153677618153677645+CDS3.584437.80035K562UCHL5
chrX153678163153678250+CDS,intron-Proximal3.0075610.31403K562RBM15
chrX153674836153674908+CDS3.620673.02990K562SRSF7
chrX153674846153674869+CDS3.304666.52344K562TRA2A
chrX153678189153678264+CDS,intron-Proximal3.0114115.01918K562DDX24
chrX153678632153678668+CDS,intron-Proximal3.261934.68114K562DDX55
chrX153677290153677302+CDS4.3284016.96713K562ZNF622
chrX153677240153677268+CDS,intron-Proximal3.8290413.55001K562ZNF800
chrX153672584153672629+CDS3.633185.73361K562YBX3
chrX153677257153677298+CDS3.5299015.37828K562UCHL5
chrX153678175153678280+CDS,intron-Proximal4.0198521.84811K562PRPF8
chrX153678049153678136+CDS,intron-Proximal3.1831415.45454K562DDX24
chrX153678065153678083+CDS3.1523310.39510K562ZNF622
chrX153677266153677302+CDS3.224434.65204K562TRA2A
chrX153672582153672676+CDS5.649434.97000K562DDX3X
chrX153678080153678133+CDS,intron-Proximal4.348785.64484HepG2PRPF8
chrX153674764153674778+CDS4.7099810.91062K562UCHL5
chrX153678558153678569+CDS3.272539.32936K562ZNF622
chrX153677036153677082+CDS,intron-Proximal3.3278720.37233K562PUM1
chrX153677241153677250+CDS4.2048715.26535K562ZNF622
chrX153677608153677645+CDS3.355414.27261HepG2GRWD1
chrX153678569153678588+CDS3.319098.95936K562ZNF622
chrX153677268153677297+CDS3.159939.39465K562ZNF800
chrX153677238153677290+CDS,intron-Proximal4.340664.59504K562RBFOX2
chrX153676834153676847+CDS4.8956111.98007K562ZNF622
chrX153677083153677099+CDS3.831039.32617K562GRWD1
chrX153677050153677095+CDS4.8744524.28921K562UCHL5
chrX153678028153678079+CDS,intron-Proximal4.739997.01471HepG2GRWD1
chrX153677062153677083+CDS3.225829.92570K562GRWD1
chrX153678082153678088+CDS,intron-Proximal5.8205557.43885K562AQR
chrX153677082153677103+CDS4.7516210.55421K562PUM1
chrX153677040153677050+CDS5.2810919.01967K562UCHL5
chrX153678407153678446+CDS3.3968513.36473K562ZNF622
chrX153674184153674231+CDS3.6563612.75382K562UCHL5
chrX153678556153678584+CDS,intron-Proximal3.919604.68902HepG2PPIG
chrX153677240153677303+CDS,intron-Proximal3.2178110.98590K562PUM1
chrX153677644153677678+CDS,intron-Proximal4.4648929.48484K562AQR
chrX153676830153676874+CDS,intron-Proximal5.5338020.19069K562UCHL5
chrX153678229153678253+CDS,intron-Proximal3.3295713.12521K562ZNF622
chrX153678188153678265+CDS,intron-Proximal3.4321111.41099HepG2PRPF8
chrX153677632153677644+CDS4.0705813.91335K562ZNF622
chrX153677240153677259+CDS,intron-Proximal3.713588.91582K562GRWD1
chrX153674184153674240+CDS3.465106.77309K562TRA2A
chrX153674791153674846+CDS3.749135.65663K562TRA2A
chrX153674849153674875+CDS5.0217813.49586K562UCHL5
chrX153678007153678048+CDS,intron-Proximal3.5393712.84418K562AQR
chrX153678198153678274+CDS,intron-Proximal3.5514710.46067HepG2AQR
chrX153676882153676907+CDS4.2304415.15889K562ZNF622
chrX153676830153676866+CDS,intron-Proximal4.202377.71540K562TRA2A
chrX153677037153677040+CDS,intron-Proximal4.8993613.28384K562UCHL5
chrX153674778153674843+CDS4.4311620.29732K562UCHL5
chrX153678556153678613+CDS,intron-Proximal3.009243.51295K562SRSF1
chrX153678074153678106+CDS,intron-Proximal3.882005.24452HepG2PPIG
chrX153677099153677104+CDS3.955007.61543K562GRWD1
chrX153678088153678116+intron-Proximal5.8060667.91144K562AQR
chrX153678183153678226+intron-Proximal3.770519.00464K562ZNF622
chrX153674915153674938+intron-Proximal5.6778910.04245K562AQR
chrX153678116153678126+intron-Proximal6.7517462.88238K562AQR
chrX153678126153678134+intron-Proximal4.5361612.35151K562AQR
chrX153677658153677683+intron-Proximal4.091953.12843K562PRPF8
chrX153677651153677698+intron-Proximal3.281535.62208HepG2PRPF8
chrX153678088153678157+intron-Proximal3.320427.41391K562RBM15
chrX153677678153677689+intron-Proximal5.4633728.17552K562AQR
chrX153673933153673978+intron-Proximal5.230166.90654K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM50A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM50A is not available on ENCORE database.

  • 104 RBPs can affect the levels of FAM50A.  








The Knockdown/knockout RNA-Seq assay for FAM50A is not available on ENCORE database.





104 RBPs can affect the gene expression of FAM50A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM50AENSG00000071859.10932.24610649.012700.522406.955606.07950HepG2ACO1
FAM50AENSG00000071859.101242.43570892.741400.476803.162302.59850HepG2AKAP1
FAM50AENSG00000071859.101309.93400878.678700.576004.968403.58510HepG2AKAP8
FAM50AENSG00000071859.10941.16040651.934100.529607.198306.02700HepG2AKAP8L
FAM50AENSG00000071859.101142.78260738.620800.629505.883104.75980HepG2ASCC1
FAM50AENSG00000071859.101326.91120925.120800.520308.292907.21130HepG2AUH
FAM50AENSG00000071859.10921.14510514.869100.839107.383905.81130HepG2BCCIP
FAM50AENSG00000071859.101127.98520872.331800.370702.894402.28330HepG2BOP1
FAM50AENSG00000071859.10702.86770502.165100.485004.210503.28350HepG2CALR
FAM50AENSG00000071859.10872.20730648.717900.427004.654903.83560HepG2CKAP4
FAM50AENSG00000071859.10632.64350800.86540-0.340201.992801.39870HepG2CPSF6
FAM50AENSG00000071859.101056.54710706.031100.581506.219904.61380HepG2CPSF7
FAM50AENSG00000071859.101638.94150779.172301.0727032.8401031.13020HepG2CELF1
FAM50AENSG00000071859.10972.87120837.653600.215802.227601.55180HepG2DAZAP1
FAM50AENSG00000071859.10728.58650559.891500.379902.526001.87510HepG2DDX21
FAM50AENSG00000071859.101166.05450855.076300.447403.201202.53450HepG2DDX3X
FAM50AENSG00000071859.10703.45060506.230300.474602.567101.81820HepG2DDX55
FAM50AENSG00000071859.10855.95190651.646700.393302.729401.72330HepG2DDX5
FAM50AENSG00000071859.101762.42030734.769501.2621019.7686018.31730HepG2DDX6
FAM50AENSG00000071859.10511.04060409.205900.320502.065101.44810HepG2DNAJC21
FAM50AENSG00000071859.10498.46610405.656300.297102.144101.55660HepG2DNAJC2
FAM50AENSG00000071859.101094.08850706.112300.631705.792904.95310HepG2EIF2S1
FAM50AENSG00000071859.101119.54090759.876000.559003.462102.69590HepG2EIF4B
FAM50AENSG00000071859.10986.37240634.064900.637407.526906.15290HepG2EWSR1
FAM50AENSG00000071859.101344.94940865.730300.635505.486604.43660HepG2FIP1L1
FAM50AENSG00000071859.102008.88780802.202201.324302.279001.36480HepG2FTO
FAM50AENSG00000071859.10265.36490459.54850-0.792206.157305.15370HepG2HNRNPC
FAM50AENSG00000071859.10936.68220740.020600.339902.122501.50500HepG2HNRNPK
FAM50AENSG00000071859.10962.30460762.993400.334704.150003.33700HepG2HNRNPL
FAM50AENSG00000071859.10616.09910456.508700.432404.057703.33440HepG2HNRNPU
FAM50AENSG00000071859.101434.48610742.363900.9502013.2652011.91110HepG2IGF2BP2
FAM50AENSG00000071859.10640.67760466.304900.458205.061704.09560HepG2ILF2
FAM50AENSG00000071859.101372.91660987.463200.475303.053202.17770HepG2LARP4
FAM50AENSG00000071859.101020.82160792.190000.365702.028701.48350HepG2MATR3
FAM50AENSG00000071859.10979.06780700.635500.482604.327203.32760HepG2MSI2
FAM50AENSG00000071859.101078.77010830.623500.377004.024103.10460HepG2NOL12
FAM50AENSG00000071859.10841.52700589.160800.514202.315301.51680HepG2PABPC1
FAM50AENSG00000071859.10681.59100843.94040-0.308202.424301.90650HepG2PTBP1
FAM50AENSG00000071859.10992.64640841.792800.237702.681802.09590HepG2PUM1
FAM50AENSG00000071859.10694.06440914.04720-0.397202.238501.66660HepG2QKI
FAM50AENSG00000071859.101029.08430519.683000.985606.931905.84170HepG2RAVER1
FAM50AENSG00000071859.101418.56270887.805900.6760011.7189010.80660HepG2RBM22
FAM50AENSG00000071859.10624.58590829.54190-0.409403.322002.58870HepG2RBM25
FAM50AENSG00000071859.10668.05950874.74680-0.388903.106702.45880HepG2RECQL
FAM50AENSG00000071859.101509.51470965.476700.644708.768607.66090HepG2RPLP0
FAM50AENSG00000071859.10726.13410377.806700.9425011.9751010.80320HepG2RPS19
FAM50AENSG00000071859.10751.31800570.889300.396102.189301.47280HepG2RPS2
FAM50AENSG00000071859.10812.36790582.788900.479103.046101.91700HepG2RPS5
FAM50AENSG00000071859.10676.76770386.260700.809006.481205.33470HepG2RRP9
FAM50AENSG00000071859.10538.66870406.528700.405902.286401.69200HepG2SAFB2
FAM50AENSG00000071859.10545.07060379.116500.523703.253002.22970HepG2SERBP1
FAM50AENSG00000071859.10771.34720474.060100.7022011.6458010.46910HepG2SMN1
FAM50AENSG00000071859.10731.04560530.823100.461602.510701.60200HepG2SMNDC1
FAM50AENSG00000071859.101479.77930954.225500.632904.142703.17740HepG2SNRNP70
FAM50AENSG00000071859.101559.963501002.723800.6375013.7393012.84890HepG2SRFBP1
FAM50AENSG00000071859.10739.87530917.14220-0.309902.821702.34490HepG2SRSF1
FAM50AENSG00000071859.10997.84400782.974000.349704.061103.32920HepG2SRSF5
FAM50AENSG00000071859.101045.76210746.132500.487006.965106.16070HepG2SRSF9
FAM50AENSG00000071859.10999.07290563.232400.826807.544105.65880HepG2STIP1
FAM50AENSG00000071859.101114.79740890.407900.324104.207703.46990HepG2SUCLG1
FAM50AENSG00000071859.10925.74050584.556900.663208.215106.65890HepG2SUPT6H
FAM50AENSG00000071859.101016.38460503.933701.0120011.035409.83450HepG2SUPV3L1
FAM50AENSG00000071859.10505.14490337.762600.580603.214402.14520HepG2TFIP11
FAM50AENSG00000071859.10546.06860757.48270-0.472104.304603.27120HepG2TIA1
FAM50AENSG00000071859.10836.61440443.504000.9155014.3563013.37410HepG2TIAL1
FAM50AENSG00000071859.10752.86740447.554000.7502011.9126010.86060HepG2TRIM56
FAM50AENSG00000071859.101085.11990740.558900.551104.836704.01920HepG2U2AF1
FAM50AENSG00000071859.101696.19680911.593100.895702.564301.61560HepG2U2AF2
FAM50AENSG00000071859.101279.05790820.113100.641103.935702.92820HepG2UBE2L3
FAM50AENSG00000071859.10719.05820297.681801.2722017.3723015.50160HepG2UCHL5
FAM50AENSG00000071859.101111.62980753.798200.560309.406708.25100HepG2UPF1
FAM50AENSG00000071859.10828.50760461.420700.844305.999104.48030HepG2UPF2
FAM50AENSG00000071859.10700.19620496.067800.497103.066502.30420HepG2XRN2
FAM50AENSG00000071859.101552.24180829.034600.9047030.5046029.18970HepG2ZNF622
FAM50AENSG00000071859.102271.786501896.988100.260003.360102.74610K562AGGF1
FAM50AENSG00000071859.102858.728002084.495800.455604.724303.35680K562AKAP8
FAM50AENSG00000071859.103205.077701973.900300.6992011.8620010.37930K562AKAP8L
FAM50AENSG00000071859.102609.097402071.093200.333104.419903.23640K562ATP5C1
FAM50AENSG00000071859.101412.973001202.444900.232702.362701.47820K562BCLAF1
FAM50AENSG00000071859.102089.104101425.188300.551606.053504.75200K562BOP1
FAM50AENSG00000071859.101899.074301515.405900.325503.196902.35210K562CPSF6
FAM50AENSG00000071859.104416.715203428.926500.365103.871602.70650K562CELF1
FAM50AENSG00000071859.101387.932701054.485500.396305.534803.66400K562DDX27
FAM50AENSG00000071859.103022.519302130.184000.504706.533305.59180K562DDX47
FAM50AENSG00000071859.101437.357901132.219300.344202.278401.44970K562EFTUD2
FAM50AENSG00000071859.101556.116001302.023100.257102.871201.63450K562EIF2S1
FAM50AENSG00000071859.101109.17490721.899900.619509.144107.70160K562EIF3G
FAM50AENSG00000071859.101361.405601080.976200.332702.909201.57990K562EWSR1
FAM50AENSG00000071859.102137.392801352.645500.660009.293607.63890K562FIP1L1
FAM50AENSG00000071859.101961.340001541.847200.347102.810501.94950K562FMR1
FAM50AENSG00000071859.101920.058401306.836200.555005.470704.13500K562FTO
FAM50AENSG00000071859.10249.13980767.22560-1.622707.854106.53620K562G3BP2
FAM50AENSG00000071859.101867.157401446.857100.367803.414602.53530K562GPKOW
FAM50AENSG00000071859.103264.123602154.394200.599309.723608.28270K562GRSF1
FAM50AENSG00000071859.10716.070201330.87990-0.8942015.0247013.71910K562HNRNPC
FAM50AENSG00000071859.101654.027101112.603700.571905.334103.99140K562HNRNPM
FAM50AENSG00000071859.102207.184101877.139400.233602.300101.48350K562HNRNPU
FAM50AENSG00000071859.102456.188801833.853200.421404.229803.25260K562HSPD1
FAM50AENSG00000071859.101181.39100892.223200.404902.945701.40500K562ILF3
FAM50AENSG00000071859.102848.103902094.807900.443105.496304.24550K562KIF1C
FAM50AENSG00000071859.101640.135201235.389800.408702.516601.62870K562KRR1
FAM50AENSG00000071859.102581.626402005.241500.364403.650702.35910K562MAK16
FAM50AENSG00000071859.102875.396302346.713100.293002.798901.88400K562MBNL1
FAM50AENSG00000071859.103937.647902971.911100.405804.056602.68850K562MSI2
FAM50AENSG00000071859.102157.528401711.009000.334405.289004.19610K562MTPAP
FAM50AENSG00000071859.102129.882901644.875400.372702.239301.46610K562NAA15
FAM50AENSG00000071859.102450.107401901.021200.366008.798007.56870K562NSUN2
FAM50AENSG00000071859.102099.236301535.568500.451004.601203.50510K562PPIG
FAM50AENSG00000071859.103817.968801957.580600.9636016.0211014.75580K562PUS1
FAM50AENSG00000071859.102807.739601907.356500.5577010.892909.73850K562RBM15
FAM50AENSG00000071859.10971.51210727.092300.418003.366701.88100K562RBM25
FAM50AENSG00000071859.101567.850901122.010300.482603.470202.55260K562RPS19
FAM50AENSG00000071859.101563.562201126.222700.473202.821201.48050K562RRP9
FAM50AENSG00000071859.102536.046901875.917100.434907.561406.26440K562SF3A3
FAM50AENSG00000071859.101060.78770797.188400.412004.013202.97590K562SF3B4
FAM50AENSG00000071859.101610.013801141.224600.496402.307701.65460K562SRSF1
FAM50AENSG00000071859.101341.487701681.25360-0.325703.215702.33020K562SYNCRIP
FAM50AENSG00000071859.101513.913601219.302800.312102.359501.49750K562TRIM56
FAM50AENSG00000071859.101622.172901128.759400.523104.758003.38290K562UCHL5
FAM50AENSG00000071859.102490.856302015.698100.305302.527101.83920K562UPF1
FAM50AENSG00000071859.102185.777201724.761000.341603.467902.49100K562WDR3
FAM50AENSG00000071859.102240.886601793.607600.321102.962202.08670K562WDR43
FAM50AENSG00000071859.103231.739402512.195000.363303.793802.75250K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM50A is not available on ENCORE database.





11 RBPs can affect the splicing of FAM50A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIFAM50AENSG00000071859.10chrX+1536780361536782791536780361536780831536782301536782790.190000.003160.04357includedK562SF3B4
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.206000.002340.08799includedHepG2BCCIP
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.270000.000010.00083includedK562HNRNPC
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.204000.005060.05409includedHepG2PRPF8
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.190000.000270.00864includedK562SRSF1
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.145000.005670.05962includedK562PRPF8
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.166000.003980.04633includedHepG2PCBP1
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.170000.005180.05236includedHepG2NCBP2
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.217000.000020.00027includedHepG2SF3B4
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.126000.003660.05126includedHepG2SRSF9
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.175000.000330.01133includedHepG2PTBP1
RIFAM50AENSG00000071859.10chrX+1536780361536782791536780361536780831536782301536782790.125000.001740.01114includedK562AQR
RIFAM50AENSG00000071859.10chrX+1536780281536782791536780281536780831536782301536782790.227000.000530.02533includedHepG2XRN2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM50A is not avaliable on ENCORE database.