EPHB6

General Information

Gene Name       : EPHB6
Gene ID             : ENSG00000106123.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EPHB6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EPHB6ENSG00000106123.110.000.040.02ENCSR000AEF
HepG2EPHB6ENSG00000106123.110.190.000.10ENCSR985KAT
K562EPHB6ENSG00000106123.117.725.096.40ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EPHB6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EPHB6 RNA is bound by 2 proteins.  







eCLIP assay for EPHB6 is not avaliable on ENCORE database.





2 proteins are bound to EPHB6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7142562043142562135+3'-UTR,CDS,intron-Distal,intron-Proximal3.443144.24159K562RBM15
chr7142564176142564285+3'-UTR,5'-UTR,CDS,intron-Proximal5.400687.81477K562SF3B4
chr7142562283142562342+3'-UTR,CDS,intron-Distal,intron-Proximal3.448363.63681K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EPHB6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EPHB6 is not available on ENCORE database.

  • 99 RBPs can affect the levels of EPHB6.  








The Knockdown/knockout RNA-Seq assay for EPHB6 is not available on ENCORE database.





99 RBPs can affect the gene expression of EPHB6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EPHB6ENSG00000106123.7155.944700.0000099999.9999035.6477034.02060HepG2AKAP1
EPHB6ENSG00000106123.710.078300.0000099999.999903.131302.41830HepG2PUM2
EPHB6ENSG00000106123.765.619103.816704.1036013.6808012.70300HepG2RBM22
EPHB6ENSG00000106123.77.729400.0000099999.999901.967301.44160HepG2RPS19
EPHB6ENSG00000106123.729.966600.0000099999.999907.734106.50380HepG2RRP9
EPHB6ENSG00000106123.7841.65510252.330801.7378023.5882020.27650K562AARS
EPHB6ENSG00000106123.71719.99710530.965801.6956043.7113039.78130K562ABCF1
EPHB6ENSG00000106123.7630.78840311.392001.0183015.5856014.35190K562AGGF1
EPHB6ENSG00000106123.7908.10380324.012701.4867024.7030022.38040K562AKAP8L
EPHB6ENSG00000106123.7391.32600739.27210-0.9177010.512508.05770K562APOBEC3C
EPHB6ENSG00000106123.7430.107601160.69630-1.4322011.4382010.36400K562AQR
EPHB6ENSG00000106123.7465.73700339.958400.454103.209202.22090K562ATP5C1
EPHB6ENSG00000106123.7753.17300301.148301.322407.953805.63530K562BCCIP
EPHB6ENSG00000106123.7612.99470291.018301.0747017.0174014.63560K562BCLAF1
EPHB6ENSG00000106123.7708.27110372.146000.9283012.8257010.30790K562CCDC124
EPHB6ENSG00000106123.7353.32280618.84220-0.808608.883506.23270K562CEBPZ
EPHB6ENSG00000106123.72113.61810273.941802.9477090.9413086.86680K562CIRBP
EPHB6ENSG00000106123.7897.81800613.946000.548203.168801.61160K562CKAP4
EPHB6ENSG00000106123.71255.78550628.089400.9994022.9317020.05840K562CPEB4
EPHB6ENSG00000106123.7522.74070310.050100.753506.243605.06770K562CPSF6
EPHB6ENSG00000106123.7213.06620452.42920-1.086406.367903.58040K562CPSF7
EPHB6ENSG00000106123.7248.61320462.29320-0.894907.008404.25990K562YBX3
EPHB6ENSG00000106123.7356.84630220.780700.692604.937603.46550K562CSTF2
EPHB6ENSG00000106123.7673.36860365.347700.882009.715407.06250K562DDX19B
EPHB6ENSG00000106123.7384.51790711.23520-0.8873012.5960010.03600K562DDX21
EPHB6ENSG00000106123.7378.10070255.169300.567204.454902.76020K562DDX27
EPHB6ENSG00000106123.7655.24210292.807201.162004.559302.40570K562DDX51
EPHB6ENSG00000106123.7540.50150276.328700.967804.484201.55890K562DDX52
EPHB6ENSG00000106123.7210.29290482.43640-1.197908.028205.23410K562DNAJC2
EPHB6ENSG00000106123.7415.16660270.844400.616102.172601.36410K562EFTUD2
EPHB6ENSG00000106123.71797.16420537.231501.7420072.5184070.02650K562EIF2S2
EPHB6ENSG00000106123.7158.06320357.53940-1.1776011.409809.71430K562EIF4A3
EPHB6ENSG00000106123.7548.37790837.83110-0.611507.633006.08500K562EIF4G2
EPHB6ENSG00000106123.7446.52990312.091000.516703.295701.86020K562EWSR1
EPHB6ENSG00000106123.7435.24870913.86670-1.0701016.7574013.78460K562EXOSC5
EPHB6ENSG00000106123.7409.25170241.272000.762203.410001.46990K562FAM120A
EPHB6ENSG00000106123.7668.29940381.775100.807705.748104.49600K562FIP1L1
EPHB6ENSG00000106123.7484.43770315.455000.618804.304003.23720K562FMR1
EPHB6ENSG00000106123.737.73140107.81620-1.514705.937204.81430K562G3BP2
EPHB6ENSG00000106123.7567.20590271.557501.062508.664206.14320K562GEMIN5
EPHB6ENSG00000106123.7407.20430590.69230-0.536704.933103.43090K562GLRX3
EPHB6ENSG00000106123.7432.25820715.79470-0.727704.293203.35570K562GRSF1
EPHB6ENSG00000106123.7372.71980693.08790-0.894906.051103.75710K562HNRNPAB
EPHB6ENSG00000106123.7453.19360246.514700.878407.994205.97140K562HNRNPF
EPHB6ENSG00000106123.7452.48670587.34310-0.376302.464701.47440K562HNRNPL
EPHB6ENSG00000106123.7206.84020531.17160-1.3607017.7112015.56690K562HNRNPU
EPHB6ENSG00000106123.71812.19370255.922802.8239028.6388025.11410K562IGF2BP2
EPHB6ENSG00000106123.7353.91680675.80060-0.933205.640303.56820K562ILF2
EPHB6ENSG00000106123.7225.99660442.13760-0.968203.999802.19810K562ILF3
EPHB6ENSG00000106123.7746.28340267.400901.4806023.9116020.33000K562LARP7
EPHB6ENSG00000106123.7704.68610280.021401.331308.532705.76090K562LIN28B
EPHB6ENSG00000106123.7628.73440385.224700.706707.151005.56000K562MBNL1
EPHB6ENSG00000106123.7500.41840288.953100.792207.189805.73940K562METAP2
EPHB6ENSG00000106123.7292.27960621.03950-1.0873018.3158016.49800K562MTPAP
EPHB6ENSG00000106123.7475.24740267.294500.830104.228302.54200K562NONO
EPHB6ENSG00000106123.7490.14980690.01110-0.493405.881704.85100K562NSUN2
EPHB6ENSG00000106123.7359.43390711.60210-0.985306.693904.79270K562PABPC1
EPHB6ENSG00000106123.7646.94150262.745501.2999013.0289010.21190K562PCBP1
EPHB6ENSG00000106123.7418.78920238.958300.809404.349203.11770K562PCBP2
EPHB6ENSG00000106123.7527.952301162.43800-1.1387014.5198012.65070K562PCBP3
EPHB6ENSG00000106123.7967.55200525.612200.8802010.457107.37450K562PKM
EPHB6ENSG00000106123.7595.34980860.90280-0.532104.926803.08870K562PNPT1
EPHB6ENSG00000106123.7439.22030891.66300-1.0216017.0938015.19310K562POLR2G
EPHB6ENSG00000106123.7735.41170433.467900.762503.088702.21450K562PPIG
EPHB6ENSG00000106123.7468.29910247.478800.920007.845506.16980K562PSIP1
EPHB6ENSG00000106123.7940.20220261.020201.848705.271804.38020K562PTBP1
EPHB6ENSG00000106123.7656.58900914.12420-0.477403.905802.94120K562PUF60
EPHB6ENSG00000106123.71449.07290952.672100.605009.594507.78470K562PUM2
EPHB6ENSG00000106123.71569.95770321.365802.2883067.2152064.44830K562PUS1
EPHB6ENSG00000106123.71232.76690250.107002.3012032.4502029.38870K562RBM22
EPHB6ENSG00000106123.7613.47740243.944601.3304016.6668013.07190K562RBM34
EPHB6ENSG00000106123.7376.87190225.849000.738605.401604.01010K562RCC2
EPHB6ENSG00000106123.7442.29000127.906401.789804.029502.79140K562RPS3
EPHB6ENSG00000106123.7618.56850821.35210-0.409102.924801.43360K562SDAD1
EPHB6ENSG00000106123.7641.31750225.428301.508303.406601.65210K562SERBP1
EPHB6ENSG00000106123.7925.38850354.283801.385105.267403.43960K562SF1
EPHB6ENSG00000106123.7995.81280680.893900.548307.196805.92870K562SF3A3
EPHB6ENSG00000106123.7570.21620281.511901.018209.237907.38500K562SF3B1
EPHB6ENSG00000106123.7281.34770112.117201.327206.933905.54200K562SF3B4
EPHB6ENSG00000106123.72013.71230692.888401.5391021.6534017.26500K562SMN1
EPHB6ENSG00000106123.7427.02840214.093000.996002.823001.78590K562SRFBP1
EPHB6ENSG00000106123.7634.77130255.923901.3104010.484009.12170K562SRSF1
EPHB6ENSG00000106123.7383.37720241.792500.664902.525801.53030K562SRSF5
EPHB6ENSG00000106123.7361.58230634.62180-0.811608.201806.18620K562SRSF7
EPHB6ENSG00000106123.760.61870148.53090-1.292902.522601.30330K562SSB
EPHB6ENSG00000106123.7278.45220486.60230-0.805302.844901.39050K562SUPT6H
EPHB6ENSG00000106123.7571.71560894.31500-0.645507.965806.56270K562SYNCRIP
EPHB6ENSG00000106123.746.24320105.83490-1.194503.616201.85810K562TAF15
EPHB6ENSG00000106123.7276.92980112.389401.300906.773604.25520K562TBRG4
EPHB6ENSG00000106123.7482.64390232.553601.053304.579502.44190K562TFIP11
EPHB6ENSG00000106123.7449.58710249.790000.847803.466002.53470K562TIA1
EPHB6ENSG00000106123.7114.83590238.02630-1.051506.236904.77750K562TIAL1
EPHB6ENSG00000106123.7620.13530245.307201.3379015.0840011.91500K562TRA2A
EPHB6ENSG00000106123.7753.07580446.303500.754703.482301.89310K562TRIP6
EPHB6ENSG00000106123.7979.39680762.215800.361603.974702.45210K562TROVE2
EPHB6ENSG00000106123.7368.70000595.55040-0.691804.521202.24230K562TUFM
EPHB6ENSG00000106123.7218.84110107.940801.019504.183903.19970K562U2AF2
EPHB6ENSG00000106123.7963.10640731.634900.396504.489403.59700K562UPF1
EPHB6ENSG00000106123.7601.75430325.797000.885104.624302.79300K562UTP18
EPHB6ENSG00000106123.72335.61080785.215301.5725033.6079030.35570K562UTP3
EPHB6ENSG00000106123.7636.001201307.74250-1.040005.284204.02670K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EPHB6 is not available on ENCORE database.





5 RBPs can affect the splicing of EPHB6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEPHB6ENSG00000106123.7chr7+1425597741425598911425588091425589441425605131425605910.354000.000050.03394includedK562ABCF1
SEEPHB6ENSG00000106123.7chr7+142563714142564071142563229142563385142564235142564360-0.348000.000140.00351excludedK562HNRNPC
A3SSEPHB6ENSG00000106123.7chr7+1425679481425681601425679661425681601425675691425677190.295000.000000.00000longerK562AQR
RIEPHB6ENSG00000106123.7chr7+142563714142564360142563714142564071142564235142564360-0.135000.003560.06745excludedK562HNRNPC
RIEPHB6ENSG00000106123.7chr7+142563714142564360142563714142564071142564235142564360-0.134000.000470.04978excludedK562ZC3H8
RIEPHB6ENSG00000106123.7chr7+142563714142564360142563714142564071142564235142564360-0.174000.003290.05454excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EPHB6 is not avaliable on ENCORE database.