DGCR6L

General Information

Gene Name       : DGCR6L
Gene ID             : ENSG00000128185.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DGCR6L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DGCR6LENSG00000128185.90.955.513.23ENCSR000AEF
HepG2DGCR6LENSG00000128185.921.546.3913.96ENCSR985KAT
K562DGCR6LENSG00000128185.948.0527.1437.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DGCR6L is not avaliable on ENCORE database.



Proteins bound to RNA
  • DGCR6L RNA is bound by 10 proteins.  







eCLIP assay for DGCR6L is not avaliable on ENCORE database.





10 proteins are bound to DGCR6L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222030222220302263-3'-UTR,CDS,intron-Distal3.350839.25119K562LIN28B
chr222030226120302315-3'-UTR,CDS,intron-Distal4.1076115.29480K562YBX3
chr222030193320302006-3'-UTR,intron-Distal3.330183.06830K562UPF1
chr222030223320302324-3'-UTR,CDS,intron-Distal4.1734910.84373K562METAP2
chr222030189920301951-3'-UTR,intron-Distal,intron-Proximal5.074735.94584K562PABPC4
chr222030281220302866-3'-UTR,CDS,intron-Distal,intron-Proximal4.961414.65563K562AQR
chr222030292020302928-3'-UTR,CDS,intron-Distal5.2055810.22679K562YBX3
chr222030292820302950-3'-UTR,CDS,intron-Distal4.4326710.66391K562YBX3
chr222030751220307561-5'-UTR,intron-Distal,intron-Proximal5.058713.85934HepG2DDX3X
chr222030745020307553-5'-UTR,CDS,intron-Distal,intron-Proximal5.092726.02664K562DDX3X
chr222030716120307182-CDS,intron-Distal,intron-Proximal5.4755313.55038K562YBX3
chr222030727220307304-CDS,intron-Distal3.035657.04063K562YBX3
chr222030372120303742-CDS,intron-Distal5.2955911.99287K562YBX3
chr222030299420303035-CDS,intron-Distal,intron-Proximal3.178693.20348K562PRPF8
chr222030718220307193-CDS,intron-Distal3.239354.29172K562YBX3
chr222030714520307162-intron-Distal,intron-Proximal3.347654.63311K562AQR
chr222030502520305086-intron-Distal4.110423.59301K562HNRNPM
chr222030349220303538-intron-Distal4.768385.17615K562AQR
chr222030531320305373-intron-Distal3.375503.43829K562EXOSC5
chr222030711820307145-intron-Distal,intron-Proximal3.450884.63311K562AQR
chr222030576420305825-intron-Distal4.611193.53404K562HNRNPM
chr222030359520303642-intron-Distal,intron-Proximal4.308244.98250K562AQR
chr222030567820305764-intron-Distal4.967084.27460K562HNRNPM
chr222030496220305015-intron-Distal3.875384.32378K562HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DGCR6L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DGCR6L is not available on ENCORE database.

  • 98 RBPs can affect the levels of DGCR6L.  








The Knockdown/knockout RNA-Seq assay for DGCR6L is not available on ENCORE database.





98 RBPs can affect the gene expression of DGCR6L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DGCR6LENSG00000128185.546.06020102.21420-1.150003.809802.56310HepG2AATF
DGCR6LENSG00000128185.5368.60640183.780301.004006.164704.82040HepG2ABCF1
DGCR6LENSG00000128185.5358.78640271.792300.400502.312601.67600HepG2AUH
DGCR6LENSG00000128185.5146.1171089.737500.703202.437201.87150HepG2BOP1
DGCR6LENSG00000128185.5213.65880142.908100.580102.756702.11470HepG2CELF1
DGCR6LENSG00000128185.5293.68770198.867300.562403.993603.01400HepG2DDX19B
DGCR6LENSG00000128185.5497.04960330.119400.590303.593602.89160HepG2DDX3X
DGCR6LENSG00000128185.5369.30440205.722400.844007.621906.60290HepG2DKC1
DGCR6LENSG00000128185.5115.5857069.408300.735702.550501.87080HepG2DNAJC21
DGCR6LENSG00000128185.5131.9701068.810900.939404.541003.74110HepG2DNAJC2
DGCR6LENSG00000128185.5228.69110110.237701.052704.947203.74740HepG2EEF2
DGCR6LENSG00000128185.547.18820103.82650-1.137703.831802.51660HepG2AGO1
DGCR6LENSG00000128185.5139.04170293.37470-1.077204.751303.86480HepG2EIF4B
DGCR6LENSG00000128185.597.33460151.59760-0.639202.310701.53410HepG2EIF4G1
DGCR6LENSG00000128185.5270.62990145.222500.898005.582404.44830HepG2EIF4G2
DGCR6LENSG00000128185.5425.61470312.082400.447503.033502.40870HepG2ETF1
DGCR6LENSG00000128185.5127.51610236.73020-0.892605.168004.10420HepG2FUBP3
DGCR6LENSG00000128185.5178.51790281.98550-0.659603.331202.60600HepG2G3BP1
DGCR6LENSG00000128185.5159.6648097.065600.717902.236901.32500HepG2GNB2L1
DGCR6LENSG00000128185.5116.0771061.124100.925203.065201.62580HepG2HNRNPA0
DGCR6LENSG00000128185.5129.1878077.948900.728802.152601.53180HepG2HNRNPC
DGCR6LENSG00000128185.5164.56130285.74200-0.796104.502003.62980HepG2HNRNPK
DGCR6LENSG00000128185.5138.5448077.433100.839203.776103.07870HepG2HNRNPU
DGCR6LENSG00000128185.5279.43740166.528900.746702.436001.66010HepG2LARP4
DGCR6LENSG00000128185.5461.97690313.039200.561403.013802.35420HepG2NCBP2
DGCR6LENSG00000128185.5239.13470152.380600.650003.525402.66490HepG2NOL12
DGCR6LENSG00000128185.5141.8290069.063301.038105.219404.23600HepG2PPIL4
DGCR6LENSG00000128185.5469.96080145.457501.6918024.0480022.52730HepG2PUF60
DGCR6LENSG00000128185.5305.57620154.406000.984709.536608.57360HepG2PUM1
DGCR6LENSG00000128185.5324.46610219.019800.566903.485902.81260HepG2PUS1
DGCR6LENSG00000128185.5228.55120302.02950-0.402201.883601.35320HepG2QKI
DGCR6LENSG00000128185.538.4884083.60550-1.119201.939101.33850HepG2RAVER1
DGCR6LENSG00000128185.5168.94370274.10540-0.698202.459601.82020HepG2RBM25
DGCR6LENSG00000128185.5249.50360114.729701.120706.222304.72740HepG2RBM27
DGCR6LENSG00000128185.5170.7615093.166300.874002.937401.84260HepG2RCC2
DGCR6LENSG00000128185.5247.46520105.798001.225807.288406.02850HepG2RPS2
DGCR6LENSG00000128185.5182.6342072.562401.331606.919505.66610HepG2RPS3A
DGCR6LENSG00000128185.5207.50720108.011000.941904.195302.85840HepG2RPS5
DGCR6LENSG00000128185.5145.1998068.954601.074205.597004.73360HepG2SAFB2
DGCR6LENSG00000128185.5319.88960211.837300.594502.459201.82380HepG2SF3A3
DGCR6LENSG00000128185.5272.17500139.463700.964508.011106.91140HepG2SLBP
DGCR6LENSG00000128185.5156.1604080.407600.957504.954204.13430HepG2SMN1
DGCR6LENSG00000128185.5160.9196085.541100.911603.813302.67510HepG2SMNDC1
DGCR6LENSG00000128185.5230.65130294.59550-0.353001.792101.36250HepG2SRFBP1
DGCR6LENSG00000128185.5271.21650143.613800.917207.055506.11980HepG2SRSF5
DGCR6LENSG00000128185.5124.63510246.54350-0.984107.770706.93010HepG2SRSF9
DGCR6LENSG00000128185.5625.54750255.760301.2902010.669609.79060HepG2SSB
DGCR6LENSG00000128185.5302.40140163.332100.888607.366606.43310HepG2SUCLG1
DGCR6LENSG00000128185.599.84630272.37930-1.4478013.3593012.26460HepG2TAF15
DGCR6LENSG00000128185.5149.76400250.29510-0.740902.727801.89700HepG2TIA1
DGCR6LENSG00000128185.5255.9043075.221501.766303.034202.51450HepG2TIAL1
DGCR6LENSG00000128185.5155.2468075.914601.032005.845405.07970HepG2TRIM56
DGCR6LENSG00000128185.5318.33750142.099901.163602.166001.39860HepG2TUFM
DGCR6LENSG00000128185.5106.21210158.66440-0.579001.866601.33960HepG2U2AF1
DGCR6LENSG00000128185.5134.0831064.999701.044503.388702.16680HepG2XPO5
DGCR6LENSG00000128185.5267.37060143.023900.902502.941902.19430HepG2XRN2
DGCR6LENSG00000128185.5319.49150206.618300.628704.861004.18780HepG2ZNF622
DGCR6LENSG00000128185.5687.64990498.485600.464003.220301.88530K562ABCF1
DGCR6LENSG00000128185.51219.31080912.636900.417905.339304.59240K562AGGF1
DGCR6LENSG00000128185.51537.943001002.825100.616802.280501.40030K562AKAP8
DGCR6LENSG00000128185.5932.550001153.20190-0.306401.867501.36730K562AQR
DGCR6LENSG00000128185.51241.45850996.383000.317203.054702.09520K562ATP5C1
DGCR6LENSG00000128185.5777.70360542.356900.519903.454502.37680K562BCLAF1
DGCR6LENSG00000128185.51612.827401090.671100.564307.965005.95340K562CCDC124
DGCR6LENSG00000128185.5396.41680609.23520-0.620003.059601.93360K562CNOT7
DGCR6LENSG00000128185.5970.75560680.341000.512805.288903.78730K562DDX3X
DGCR6LENSG00000128185.51481.20760695.526201.0905020.1973018.59400K562DDX47
DGCR6LENSG00000128185.5919.92710689.763000.415304.251102.52380K562DDX6
DGCR6LENSG00000128185.51035.99300747.241100.471306.154004.32360K562EIF2S1
DGCR6LENSG00000128185.51302.49310851.653300.6128010.052708.81330K562EIF2S2
DGCR6LENSG00000128185.5622.99590377.321400.723303.826802.62030K562EIF3A
DGCR6LENSG00000128185.5451.58240234.531200.9451010.053608.52670K562EIF3G
DGCR6LENSG00000128185.52109.740601343.118800.6514012.6347010.69630K562EIF4G2
DGCR6LENSG00000128185.5826.42640620.415100.413603.917102.34190K562EWSR1
DGCR6LENSG00000128185.5758.95150358.357601.0825015.1936013.04740K562FIP1L1
DGCR6LENSG00000128185.512.20890125.99850-3.367406.358405.18920K562G3BP2
DGCR6LENSG00000128185.52231.261501134.800200.975306.534905.36670K562GRSF1
DGCR6LENSG00000128185.5156.07120334.73880-1.100808.365706.15750K562HNRNPK
DGCR6LENSG00000128185.5955.12910485.834600.9751013.2853011.58720K562HSPD1
DGCR6LENSG00000128185.5671.38590335.320401.001502.374601.44340K562IGF2BP2
DGCR6LENSG00000128185.5516.05460341.011900.597604.900003.22690K562IGF2BP3
DGCR6LENSG00000128185.5339.08390555.96480-0.713403.479601.86010K562ILF2
DGCR6LENSG00000128185.5595.45830352.274000.757207.987806.52750K562MAGOH
DGCR6LENSG00000128185.51235.12920964.714700.356403.258402.06500K562MAK16
DGCR6LENSG00000128185.5595.88530351.538900.761306.932905.38830K562MATR3
DGCR6LENSG00000128185.5843.43120682.156500.306102.797701.98330K562MTPAP
DGCR6LENSG00000128185.5803.37120368.336501.124905.408703.45250K562NONO
DGCR6LENSG00000128185.5396.31900585.29570-0.562502.550401.37830K562PABPC1
DGCR6LENSG00000128185.5460.55160344.410300.419102.701201.36810K562PCBP1
DGCR6LENSG00000128185.5664.49370380.289100.805109.338707.90400K562POLR2G
DGCR6LENSG00000128185.5820.61710406.829701.0122013.7160011.46250K562PPIG
DGCR6LENSG00000128185.5448.00460342.266300.388302.387301.76320K562PTBP1
DGCR6LENSG00000128185.51841.484801527.163100.269902.217701.35640K562PUM2
DGCR6LENSG00000128185.5504.05010345.309900.545603.488602.24150K562NELFE
DGCR6LENSG00000128185.51330.59110369.784901.8472022.4413020.14340K562RPS19
DGCR6LENSG00000128185.5423.57170223.192200.924206.444204.83600K562RPS3
DGCR6LENSG00000128185.5559.29880335.550200.737007.060005.93870K562SRSF1
DGCR6LENSG00000128185.5363.57500215.417700.755003.829102.56140K562SRSF4
DGCR6LENSG00000128185.5619.07240316.939300.9658011.360009.08220K562SRSF5
DGCR6LENSG00000128185.532.91640123.66050-1.909502.923001.40430K562TAF15
DGCR6LENSG00000128185.5620.27930339.566100.869106.693805.55240K562TARDBP
DGCR6LENSG00000128185.5680.64650327.558401.0551015.1463013.11380K562TIA1
DGCR6LENSG00000128185.5567.00050321.509300.818406.179704.38840K562TRA2A
DGCR6LENSG00000128185.543.63840125.93060-1.529002.937602.10990K562U2AF2
DGCR6LENSG00000128185.51102.24070803.650400.455706.307605.27550K562UPF1
DGCR6LENSG00000128185.5655.54820379.055600.790203.113101.80510K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DGCR6L is not available on ENCORE database.





11 RBPs can affect the splicing of DGCR6L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.352000.007070.09628excludedK562SF3B4
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.105000.003590.03541excludedK562AQR
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.151000.000080.00500excludedK562FXR1
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.177000.000000.00008excludedK562HNRNPA1
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.100000.000070.00184excludedK562PUS1
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.242000.000000.00000excludedK562HNRNPL
SEDGCR6LENSG00000128185.5chr22-2030364120303742203028582030299920307161203073220.084000.000140.08210includedK562PUM2
SEDGCR6LENSG00000128185.5chr22-2030364120303742203028582030299920307161203073220.110000.000000.00014includedK562EIF4G2
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.068000.003730.08970excludedK562UTP18
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307322-0.076000.002270.05189excludedK562AGGF1
SEDGCR6LENSG00000128185.5chr22-203036412030374220302858203029992030716120307237-0.495000.000000.00000excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DGCR6L is not avaliable on ENCORE database.