CYFIP1

General Information

Gene Name       : CYFIP1
Gene ID             : ENSG00000273749.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CYFIP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CYFIP1ENSG00000273749.410.6815.4313.05ENCSR000AEF
HepG2CYFIP1ENSG00000273749.441.9428.5135.23ENCSR985KAT
K562CYFIP1ENSG00000273749.422.9919.0521.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CYFIP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CYFIP1 RNA is bound by 25 proteins.  







eCLIP assay for CYFIP1 is not avaliable on ENCORE database.





25 proteins are bound to CYFIP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr152300322823003279+3'-UTR5.191215.74792HepG2SUB1
chr152292807822928137+3'-UTR,CDS,intron-Proximal3.874195.58951HepG2SF3B4
chr152292807422928160+3'-UTR,CDS,intron-Proximal4.4659710.68651K562SF3B4
chr152295603122956091+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal6.5619827.05193HepG2RBFOX2
chr152300312123003163+3'-UTR4.884724.29122HepG2SUB1
chr152295640022956493+3'-UTR,CDS,intron-Distal,intron-Proximal3.692386.58004HepG2U2AF2
chr152292843122928508+3'-UTR,CDS3.549644.85828HepG2BCLAF1
chr152292840722928511+3'-UTR,CDS,intron-Proximal3.6418110.81930HepG2PPIG
chr152292815222928206+3'-UTR,CDS3.368204.24993HepG2PPIG
chr152295610422956157+3'-UTR,CDS,intron-Distal4.8416521.78362HepG2RBFOX2
chr152300346923003551+3'-UTR6.2264124.15382HepG2SUB1
chr152300330123003394+3'-UTR3.874567.64164K562YBX3
chr152292843422928500+3'-UTR,CDS3.927553.82000HepG2GRWD1
chr152292840622928503+3'-UTR,CDS,intron-Proximal3.709807.99428K562DDX24
chr152292813222928205+3'-UTR,CDS4.589476.85891K562DDX24
chr152295528022955306+5'-UTR,CDS,intron-Proximal4.819794.13847K562AQR
chr152295527522955374+5'-UTR,CDS,intron-Proximal3.390407.89388HepG2PRPF8
chr152295530622955339+5'-UTR,intron-Proximal4.992114.65563K562AQR
chr152295587822955942+5'-UTR,intron-Distal,intron-Proximal8.2598376.07391HepG2RBFOX2
chr152295583722955878+5'-UTR,intron-Distal7.5773050.53796HepG2RBFOX2
chr152295586522955930+5'-UTR,intron-Distal4.525973.05187HepG2QKI
chr152295578622955818+5'-UTR,intron-Distal5.4668610.00219HepG2RBFOX2
chr152292598122926065+CDS4.833087.86337HepG2GRWD1
chr152292971422929806+CDS5.178077.95223HepG2BCLAF1
chr152295513122955225+CDS,intron-Proximal3.209276.06438HepG2BCLAF1
chr152299933822999395+CDS,intron-Proximal3.752954.29397K562FMR1
chr152292971522929793+CDS3.127823.63043HepG2GRWD1
chr152292981822929884+CDS4.337604.91614HepG2GRWD1
chr152295425522954365+CDS4.935775.76079K562FXR2
chr152295420822954259+CDS,intron-Proximal3.682217.69921HepG2PPIG
chr152292598722926104+CDS,intron-Proximal3.119474.07440K562PRPF8
chr152296922722969318+CDS4.118686.26041K562FXR2
chr152295513022955181+CDS,intron-Proximal3.201565.54854HepG2GRWD1
chr152292586922925945+CDS,intron-Proximal3.387095.50267HepG2PRPF8
chr152295420922954289+CDS,intron-Proximal3.599385.58683HepG2GRWD1
chr152294084122940895+CDS,intron-Proximal3.940995.05356HepG2PRPF8
chr152295518822955241+CDS3.474708.43905HepG2PPIG
chr152294077922940850+CDS,intron-Proximal4.742075.12594K562PUM1
chr152295430322954377+CDS,intron-Proximal3.347184.04629HepG2G3BP1
chr152296243922962550+CDS,intron-Proximal3.252674.96885HepG2G3BP1
chr152295513222955230+CDS,intron-Proximal3.104729.05439K562ZNF622
chr152295513222955263+CDS,intron-Proximal3.211867.18951HepG2G3BP1
chr152295432422954336+CDS3.258228.37630K562YBX3
chr152299941222999492+CDS4.730406.26177K562FMR1
chr152295418622954264+CDS,intron-Proximal3.682497.55682HepG2BUD13
chr152299012522990194+CDS3.776858.84704K562YBX3
chr152296243922962473+CDS,intron-Proximal4.552515.87734K562LIN28B
chr152296929522969341+CDS3.717533.25175K562YBX3
chr152295421022954262+CDS3.819243.19539K562YBX3
chr152299780922997870+CDS,intron-Proximal3.575513.59112HepG2PPIG
chr152293917022939256+CDS,intron-Proximal3.671635.15776HepG2BCLAF1
chr152295421222954352+CDS3.845418.46004K562FMR1
chr152295431822954324+CDS3.472898.00668K562YBX3
chr152295433622954343+CDS3.191297.98960K562YBX3
chr152295820222958294+CDS4.212157.57065K562FXR2
chr152295513022955188+CDS,intron-Proximal3.701979.99012HepG2PPIG
chr152293587822935938+CDS4.015703.36483HepG2G3BP1
chr152295825722958343+CDS,intron-Proximal4.741326.23323K562UCHL5
chr152296243922962570+CDS,intron-Proximal3.551555.60389HepG2PPIG
chr152294079022940850+CDS,intron-Proximal4.359804.72880HepG2GRWD1
chr152295420322954259+CDS,intron-Proximal3.461593.27569HepG2BCLAF1
chr152295518222955257+CDS4.189886.81811K562UCHL5
chr152296230322962331+CDS4.377675.66624K562LIN28B
chr152295829422958345+CDS,intron-Proximal4.808895.76079K562FXR2
chr152294704822947087+CDS,intron-Proximal3.584683.86355HepG2PPIG
chr152293376822933825+CDS4.718387.21258K562LIN28B
chr152294696822947087+CDS,intron-Proximal5.200367.80708K562FXR2
chr152296079422960859+CDS3.054703.22540HepG2G3BP1
chr152295518122955240+CDS3.583535.28199HepG2GRWD1
chr152292971122929768+CDS,intron-Proximal3.575514.22917HepG2PPIG
chr152295562722955717+intron-Distal4.459145.44904K562TARDBP
chr152290862822908685+intron-Distal5.067224.67055K562EIF4G2
chr152300188023001943+intron-Distal3.953773.79098HepG2SUGP2
chr152290656722906656+intron-Distal5.119355.31214HepG2XPO5
chr152289388322893917+intron-Distal4.093613.62366HepG2HNRNPM
chr152290878122908840+intron-Distal5.712899.02011K562EIF4G2
chr152289359522893679+intron-Distal3.508646.42612HepG2HNRNPM
chr152290871422908781+intron-Distal6.4186017.92721K562EIF4G2
chr152295564222955697+intron-Distal4.6860116.47398HepG2RBFOX2
chr152289324822893308+intron-Distal5.079158.59719HepG2HNRNPM
chr152299788822997917+intron-Proximal4.784594.65563K562AQR
chr152295506822955129+intron-Proximal3.289234.05505HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CYFIP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CYFIP1 is not available on ENCORE database.

  • 80 RBPs can affect the levels of CYFIP1.  








The Knockdown/knockout RNA-Seq assay for CYFIP1 is not available on ENCORE database.





80 RBPs can affect the gene expression of CYFIP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CYFIP1ENSG00000068793.132425.891401722.221400.4941011.7954010.72750HepG2ACO1
CYFIP1ENSG00000068793.133527.151502040.308100.789609.570008.64520HepG2AKAP1
CYFIP1ENSG00000068793.132521.602701951.492200.369705.517704.66800HepG2CELF1
CYFIP1ENSG00000068793.131807.401601411.336500.356803.153602.43320HepG2DDX21
CYFIP1ENSG00000068793.131145.805701381.04220-0.269402.112801.32560HepG2DDX24
CYFIP1ENSG00000068793.131159.005701647.73700-0.507608.993307.91110HepG2DKC1
CYFIP1ENSG00000068793.131233.129901783.30070-0.532204.419703.61550HepG2EIF4A3
CYFIP1ENSG00000068793.131809.778102070.15620-0.193902.039701.30210HepG2EIF4G1
CYFIP1ENSG00000068793.132472.427602905.28800-0.232803.076902.44820HepG2ETF1
CYFIP1ENSG00000068793.131555.155001115.166500.479705.327404.24620HepG2FUBP3
CYFIP1ENSG00000068793.132374.615601799.833800.399703.215202.47090HepG2FXR1
CYFIP1ENSG00000068793.13944.194401269.23390-0.426803.840803.09830HepG2HNRNPA1
CYFIP1ENSG00000068793.132511.810801691.019400.570706.993705.91910HepG2HNRNPK
CYFIP1ENSG00000068793.131651.021901911.63100-0.211402.903702.21610HepG2HNRNPL
CYFIP1ENSG00000068793.131085.377101331.25590-0.294602.299901.43370HepG2HNRNPM
CYFIP1ENSG00000068793.13980.944801402.42130-0.515708.990207.94550HepG2HNRNPU
CYFIP1ENSG00000068793.132160.514601696.718900.348502.606301.94940HepG2IGF2BP2
CYFIP1ENSG00000068793.132249.491101706.804700.398202.415301.48930HepG2KHSRP
CYFIP1ENSG00000068793.131467.570601800.46470-0.294901.862501.31950HepG2MAGOH
CYFIP1ENSG00000068793.132086.390801703.388800.292503.950103.25150HepG2PCBP1
CYFIP1ENSG00000068793.131137.956701564.76640-0.459502.484701.32570HepG2PRPF6
CYFIP1ENSG00000068793.132637.515102108.510000.322906.414405.59000HepG2PUM1
CYFIP1ENSG00000068793.132923.139602107.004800.472207.072806.01900HepG2PUM2
CYFIP1ENSG00000068793.131465.564801754.21560-0.259403.279602.62310HepG2PUS1
CYFIP1ENSG00000068793.131490.001101877.14860-0.333203.679602.97500HepG2QKI
CYFIP1ENSG00000068793.131551.552201990.07620-0.359103.323202.58510HepG2RPLP0
CYFIP1ENSG00000068793.131242.955401022.129600.282102.046201.51060HepG2RPS19
CYFIP1ENSG00000068793.131560.238201248.939300.321004.514503.72500HepG2SAFB2
CYFIP1ENSG00000068793.131729.366201456.509700.247603.437402.73310HepG2SMN1
CYFIP1ENSG00000068793.133609.504802742.552200.396208.862808.10580HepG2SRFBP1
CYFIP1ENSG00000068793.13949.001701387.69920-0.548204.851402.81430HepG2SRP68
CYFIP1ENSG00000068793.132420.624501961.134100.303604.216203.47230HepG2SRSF5
CYFIP1ENSG00000068793.131479.357401814.94290-0.295003.811003.01360HepG2SRSF7
CYFIP1ENSG00000068793.131852.188501532.384700.273403.607102.99540HepG2SRSF9
CYFIP1ENSG00000068793.131350.511902381.07340-0.8181027.6909026.44680HepG2SSB
CYFIP1ENSG00000068793.131521.375802088.10820-0.456803.576502.13250HepG2SSRP1
CYFIP1ENSG00000068793.132119.868201693.047600.324304.157703.49160HepG2TAF15
CYFIP1ENSG00000068793.13847.727301362.84840-0.685008.302807.52090HepG2TIAL1
CYFIP1ENSG00000068793.133012.564502053.884300.552505.115803.95890HepG2UBE2L3
CYFIP1ENSG00000068793.13862.403601328.02880-0.622904.558603.25230HepG2UPF2
CYFIP1ENSG00000068793.13980.582201427.77100-0.542105.108404.13060HepG2XRN2
CYFIP1ENSG00000068793.131054.476001509.49300-0.5175010.522109.35280HepG2ZC3H8
CYFIP1ENSG00000068793.131001.838301435.33560-0.518703.473702.01330HepG2ZRANB2
CYFIP1ENSG00000068793.133542.150701854.134800.9338035.8631033.87930K562AGGF1
CYFIP1ENSG00000068793.132569.754002037.532800.334703.342902.24030K562AKAP8
CYFIP1ENSG00000068793.132346.528801929.340500.282302.491301.87120K562AKAP8L
CYFIP1ENSG00000068793.131581.214002269.13980-0.521106.918604.85490K562APOBEC3C
CYFIP1ENSG00000068793.131382.831902033.93420-0.556606.062605.25170K562AQR
CYFIP1ENSG00000068793.132634.710502024.398000.380103.042002.08520K562ATP5C1
CYFIP1ENSG00000068793.13686.91600875.78180-0.350402.194601.42430K562BOP1
CYFIP1ENSG00000068793.131338.949101966.24170-0.554303.056101.93090K562CNOT7
CYFIP1ENSG00000068793.132384.609301923.380600.310004.157502.77990K562CPEB4
CYFIP1ENSG00000068793.13784.689201051.52890-0.422303.454802.43020K562EFTUD2
CYFIP1ENSG00000068793.13883.699601632.80060-0.8857015.1519013.14070K562EIF4A3
CYFIP1ENSG00000068793.132067.736002571.71090-0.314704.757403.54000K562EIF4G2
CYFIP1ENSG00000068793.131161.025001698.04390-0.548509.538208.49570K562FXR1
CYFIP1ENSG00000068793.13809.250701088.89280-0.428202.473901.81160K562G3BP2
CYFIP1ENSG00000068793.131259.468801787.89740-0.505404.511903.55100K562GRSF1
CYFIP1ENSG00000068793.13855.879101209.25520-0.498605.324904.52250K562HNRNPC
CYFIP1ENSG00000068793.13499.46960907.80030-0.862008.830406.99860K562HNRNPM
CYFIP1ENSG00000068793.131294.965901858.95610-0.521608.644507.07740K562HNRNPU
CYFIP1ENSG00000068793.131956.578901567.190200.320102.710001.53310K562IGF2BP3
CYFIP1ENSG00000068793.132615.604802047.409900.353203.956202.94710K562KIF1C
CYFIP1ENSG00000068793.131276.560601615.63750-0.339803.178302.18410K562MATR3
CYFIP1ENSG00000068793.132958.492102293.630600.367104.583803.35230K562MBNL1
CYFIP1ENSG00000068793.131175.741801572.32470-0.419306.748305.53430K562MTPAP
CYFIP1ENSG00000068793.132097.659401607.677900.383702.437001.62080K562NAA15
CYFIP1ENSG00000068793.132139.825702813.24790-0.394704.386102.48260K562NOL12
CYFIP1ENSG00000068793.131066.880401313.48970-0.300002.645101.86440K562POLR2G
CYFIP1ENSG00000068793.13596.388001023.26470-0.778909.037807.68050K562PRPF8
CYFIP1ENSG00000068793.13895.009301573.00100-0.8135014.9845013.50520K562PTBP1
CYFIP1ENSG00000068793.132180.066302805.85160-0.364103.858702.90010K562PUF60
CYFIP1ENSG00000068793.132479.993401913.167200.374303.651603.03970K562PUS1
CYFIP1ENSG00000068793.132657.257201864.266600.511209.543908.46660K562RBM15
CYFIP1ENSG00000068793.131082.057001508.03310-0.478904.892403.73630K562RBM22
CYFIP1ENSG00000068793.13934.884001170.42410-0.324202.464001.44650K562SAFB
CYFIP1ENSG00000068793.132319.638001317.140200.816403.712602.25520K562SF1
CYFIP1ENSG00000068793.13879.739701131.84940-0.363503.507202.54040K562SF3B4
CYFIP1ENSG00000068793.132125.732601766.105300.267303.895402.80300K562SRPK2
CYFIP1ENSG00000068793.131241.940401542.12440-0.312302.808102.09720K562SRSF1
CYFIP1ENSG00000068793.13960.417601317.49660-0.456105.223804.08710K562SYNCRIP
CYFIP1ENSG00000068793.131269.444401560.60340-0.297902.099701.47720K562TARDBP
CYFIP1ENSG00000068793.131684.363801290.650600.384003.100601.61720K562TRIP6
CYFIP1ENSG00000068793.13776.262301089.76900-0.489405.578304.43840K562U2AF2
CYFIP1ENSG00000068793.132013.165701549.110000.377902.719801.52970K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CYFIP1 is not available on ENCORE database.





10 RBPs can affect the splicing of CYFIP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551322295528022956437229565850.103000.000800.01727includedK562SRSF1
SECYFIP1ENSG00000068793.13chr15+229993382299957722998423229985182300009523000243-0.070000.001930.03549excludedK562SRSF1
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551322295528022956437229565850.210000.000000.00001includedHepG2QKI
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551322295528022956437229565850.070000.001530.07613includedHepG2NCBP2
SECYFIP1ENSG00000068793.13chr15+229259752292606522925776229258992292812822928206-0.156000.000000.00009excludedHepG2SF3A3
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551422295528022956437229565850.088000.000100.01819includedHepG2SSB
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551322295528022956437229565850.111000.000050.00444includedHepG2SF3B4
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551322295528022956437229565850.151000.000220.03571includedK562RBM22
SECYFIP1ENSG00000068793.13chr15+2295603822956186229551322295528022956437229565850.096000.000420.01908includedK562TARDBP
MXECYFIP1ENSG00000068793.13chr15+22925776229258992292597522926065228926622289278122928128229282060.314000.000000.004481includedK562HLTF
MXECYFIP1ENSG00000068793.13chr15+22925776229258992292597522926065228926622289278122928128229282060.229000.000020.001041includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CYFIP1 is not avaliable on ENCORE database.