CLN6

General Information

Gene Name       : CLN6
Gene ID             : ENSG00000128973.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CLN6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CLN6ENSG00000128973.1225.5735.4730.52ENCSR000AEF
HepG2CLN6ENSG00000128973.1241.0027.4334.22ENCSR985KAT
K562CLN6ENSG00000128973.1235.9728.6532.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CLN6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CLN6 RNA is bound by 23 proteins.  







eCLIP assay for CLN6 is not avaliable on ENCORE database.





23 proteins are bound to CLN6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr156849936968499462-3'-UTR,intron-Distal3.939883.80037K562FUS
chr156850025768500365-3'-UTR,intron-Distal,intron-Proximal5.0425140.25363K562TARDBP
chr156850002368500086-3'-UTR,intron-Distal3.455644.85046K562NONO
chr156850002368500074-3'-UTR,intron-Distal3.349734.74394K562EIF4G2
chr156849998368500086-3'-UTR,intron-Distal4.914826.04125HepG2LIN28B
chr156849980768499964-3'-UTR,intron-Distal,intron-Proximal4.910888.41602K562FUS
chr156849982268499878-3'-UTR,intron-Distal,intron-Proximal3.307923.84859K562NONO
chr156849935668499442-3'-UTR,intron-Distal3.058204.38238K562CSTF2T
chr156849936368499454-3'-UTR,intron-Distal3.606664.61345HepG2FAM120A
chr156850026768500353-3'-UTR,intron-Distal,intron-Proximal4.0935018.80624K562UPF1
chr156850030968500372-3'-UTR,intron-Distal,intron-Proximal3.246314.76726K562DDX6
chr156850005268500133-3'-UTR,intron-Distal4.913925.41597HepG2UPF1
chr156850197268502049-3'-UTR,CDS,intron-Distal,intron-Proximal3.152446.00907HepG2PPIG
chr156849981168499941-3'-UTR,intron-Distal,intron-Proximal4.179747.57190HepG2UPF1
chr156849980368499909-3'-UTR,intron-Distal,intron-Proximal4.4312012.76076K562UPF1
chr156850027468500309-3'-UTR,intron-Distal,intron-Proximal4.136895.80675K562EIF4G2
chr156850002168500112-3'-UTR,intron-Distal4.170627.25541K562XRN2
chr156850016668500223-3'-UTR,intron-Distal,intron-Proximal5.164305.17229HepG2UPF1
chr156852196168522004-5'-UTR,intron-Distal5.1924516.03443HepG2DDX3X
chr156852184868522012-5'-UTR,CDS,intron-Distal,intron-Proximal3.589637.73893K562DDX3X
chr156852189768522047-5'-UTR,CDS,intron-Distal,intron-Proximal3.148106.94422HepG2NCBP2
chr156852185868521958-5'-UTR,CDS,intron-Distal4.4398424.39805HepG2DDX3X
chr156850415068504202-CDS,intron-Distal,intron-Proximal3.812047.22820K562YBX3
chr156850395868504018-CDS,intron-Distal,intron-Proximal3.513025.62208HepG2PRPF8
chr156850399368504109-CDS,intron-Distal,intron-Proximal4.153717.52225K562UCHL5
chr156850658868506653-CDS,intron-Distal,intron-Proximal3.074804.39054HepG2PRPF8
chr156849925168499303-intron-Distal,intron-Proximal3.608964.25264K562NONO
chr156850334568503410-intron-Distal4.125273.94684HepG2CSTF2T
chr156852160568521655-intron-Distal3.906223.06347K562NONO
chr156852128268521330-intron-Distal3.157063.14895K562NONO
chr156852168668521744-intron-Distal4.307923.76710K562NONO
chr156852163468521700-intron-Distal3.799603.40229HepG2CSTF2T
chr156850130868501371-intron-Distal4.833306.93811K562NONO
chr156850248068502548-intron-Distal3.100784.07684K562DROSHA
chr156850141568501488-intron-Distal3.067194.92335K562NONO
chr156849924368499301-intron-Distal,intron-Proximal3.305184.00685K562TIA1
chr156850193768501973-intron-Distal,intron-Proximal4.819255.34533K562NONO
chr156851351268513566-intron-Distal4.711964.36078K562GTF2F1
chr156852150768521571-intron-Distal3.428424.59961K562NONO
chr156850249468502562-intron-Distal3.728384.40053K562GTF2F1
chr156850156168501609-intron-Distal3.306923.58549K562NONO
chr156850250568502552-intron-Distal4.701903.17679K562DDX52
chr156850622168506314-intron-Distal3.337574.02206K562CSTF2T
chr156852094268521094-intron-Distal3.892523.94652K562FUS
chr156850250568502570-intron-Distal4.818614.86316HepG2FAM120A
chr156850248768502560-intron-Distal4.591946.52653K562GEMIN5
chr156850166868501757-intron-Distal4.3489510.06641K562NONO
chr156852133068521404-intron-Distal3.009453.52648K562NONO
chr156852164368521764-intron-Distal3.625324.36583K562XRN2
chr156850249968502577-intron-Distal4.620574.36329HepG2PRPF4
chr156850367668503750-intron-Distal,intron-Proximal3.573255.00766K562EWSR1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CLN6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CLN6 is not available on ENCORE database.

  • 83 RBPs can affect the levels of CLN6.  








The Knockdown/knockout RNA-Seq assay for CLN6 is not available on ENCORE database.





83 RBPs can affect the gene expression of CLN6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CLN6ENSG00000128973.7497.97770686.46230-0.463104.699503.84550HepG2AUH
CLN6ENSG00000128973.7293.83900431.75490-0.555202.815001.90940HepG2BCLAF1
CLN6ENSG00000128973.7121.13210234.70760-0.954305.765904.70590HepG2CALR
CLN6ENSG00000128973.7203.99030380.01370-0.897606.412605.26980HepG2CIRBP
CLN6ENSG00000128973.7309.60750441.92340-0.513404.469903.66360HepG2CKAP4
CLN6ENSG00000128973.7199.68610125.007300.675602.214101.53520HepG2CNOT7
CLN6ENSG00000128973.7240.36710467.69980-0.9603011.6234010.48190HepG2CELF1
CLN6ENSG00000128973.7377.08000255.681300.560403.882602.52500HepG2DDX1
CLN6ENSG00000128973.7319.14730488.51760-0.614203.285002.45250HepG2DDX55
CLN6ENSG00000128973.7186.90090397.77380-1.089708.205507.19420HepG2DDX6
CLN6ENSG00000128973.7147.18310290.71170-0.982004.944703.46140HepG2AGO1
CLN6ENSG00000128973.7260.61960382.41200-0.553202.926802.31740HepG2EIF2S1
CLN6ENSG00000128973.7290.76480422.62110-0.539502.754902.11700HepG2EIF4A3
CLN6ENSG00000128973.7336.22590475.27930-0.499303.149602.28280HepG2EIF4G2
CLN6ENSG00000128973.7586.30180426.374200.459402.687902.00620HepG2FXR1
CLN6ENSG00000128973.7296.14510395.54180-0.417501.888901.33390HepG2G3BP1
CLN6ENSG00000128973.7415.51640281.543500.561403.343402.58750HepG2HNRNPC
CLN6ENSG00000128973.7234.41840400.48170-0.772705.290004.34670HepG2HNRNPK
CLN6ENSG00000128973.7565.25490426.522900.406202.200301.61280HepG2MAGOH
CLN6ENSG00000128973.7185.49290264.88920-0.514002.611401.43130HepG2NAA15
CLN6ENSG00000128973.7178.2027044.988101.985806.086103.25150HepG2NUFIP2
CLN6ENSG00000128973.7181.39890299.94300-0.725505.367604.32470HepG2PRPF4
CLN6ENSG00000128973.7267.87910376.89410-0.492602.227601.49980HepG2PRPF8
CLN6ENSG00000128973.7519.12490389.882400.412903.314702.72660HepG2PTBP1
CLN6ENSG00000128973.7879.69500505.335100.7997015.6621014.48780HepG2PUM1
CLN6ENSG00000128973.7322.47620422.19770-0.388702.086801.53230HepG2QKI
CLN6ENSG00000128973.7212.9748045.294802.233204.675902.25480HepG2RBM17
CLN6ENSG00000128973.7788.88860658.751800.260001.834001.38960HepG2RBM22
CLN6ENSG00000128973.7225.50220383.19220-0.764905.722104.78400HepG2RBM25
CLN6ENSG00000128973.7522.71640380.633100.457502.254701.36840HepG2RBM27
CLN6ENSG00000128973.7203.92580475.38080-1.2210013.4472012.14950HepG2RPLP0
CLN6ENSG00000128973.7523.16670358.341400.545803.140001.99100HepG2RPS5
CLN6ENSG00000128973.7208.56990372.83040-0.838004.971803.95210HepG2RRP9
CLN6ENSG00000128973.7183.6075043.706602.070606.579404.33920HepG2SF1
CLN6ENSG00000128973.7166.6361042.496001.971204.392402.49700HepG2SFPQ
CLN6ENSG00000128973.7385.75340290.439400.409302.752402.10940HepG2SMN1
CLN6ENSG00000128973.7156.6816039.149002.000704.729502.90770HepG2SNRNP200
CLN6ENSG00000128973.7403.13080744.03370-0.8841014.9324014.01440HepG2SRFBP1
CLN6ENSG00000128973.7910.59680423.661201.1038023.6066022.52060HepG2SRSF1
CLN6ENSG00000128973.7306.21780433.55880-0.501703.906203.09990HepG2SRSF7
CLN6ENSG00000128973.7214.92920344.68710-0.681405.443204.71390HepG2SRSF9
CLN6ENSG00000128973.7243.06120486.32400-1.000607.395506.37520HepG2SUPV3L1
CLN6ENSG00000128973.7208.43870325.97340-0.645103.576502.46060HepG2TFIP11
CLN6ENSG00000128973.7198.92060333.44470-0.745304.513903.72100HepG2U2AF1
CLN6ENSG00000128973.7244.54790345.70500-0.499403.367802.61020HepG2UPF1
CLN6ENSG00000128973.7562.34140333.765100.752509.024308.04350HepG2UTP3
CLN6ENSG00000128973.71483.24170914.046900.6983010.763008.27270K562APOBEC3C
CLN6ENSG00000128973.7629.370801048.46750-0.736304.569503.84990K562AQR
CLN6ENSG00000128973.7559.57510731.88170-0.387303.386102.36640K562ATP5C1
CLN6ENSG00000128973.7457.07010609.14090-0.414403.077801.48030K562CEBPZ
CLN6ENSG00000128973.7815.93080660.291900.305202.310201.30850K562CPEB4
CLN6ENSG00000128973.7963.583301273.48900-0.402303.657002.53260K562CELF1
CLN6ENSG00000128973.7914.01750683.457700.419304.589303.77760K562DDX47
CLN6ENSG00000128973.7618.75320750.66560-0.278802.125901.36970K562DKC1
CLN6ENSG00000128973.7606.34350392.673600.626706.375405.18430K562EIF3G
CLN6ENSG00000128973.7485.01430376.444000.365502.436701.37510K562EIF4B
CLN6ENSG00000128973.71322.060101035.856600.351904.017502.88850K562EIF4G2
CLN6ENSG00000128973.7528.07360364.885800.533204.240902.59440K562EWSR1
CLN6ENSG00000128973.7465.13580607.83840-0.386002.663401.42240K562EXOSC5
CLN6ENSG00000128973.7282.39450420.09340-0.573003.899201.99460K562FASTKD2
CLN6ENSG00000128973.7232.31290386.20020-0.733303.111801.90360K562FKBP4
CLN6ENSG00000128973.7212.85450347.16000-0.705705.113203.22190K562FUS
CLN6ENSG00000128973.7902.11680434.724601.0531020.6530019.11360K562FXR1
CLN6ENSG00000128973.766.58710205.55270-1.6262010.518508.96700K562G3BP2
CLN6ENSG00000128973.7885.086701332.52580-0.590307.069405.85240K562GRSF1
CLN6ENSG00000128973.7185.19590384.74610-1.054906.419404.47990K562HNRNPK
CLN6ENSG00000128973.7590.74300740.30370-0.325602.153101.43590K562KIF1C
CLN6ENSG00000128973.7162.72230254.67770-0.646302.641101.73140K562KRR1
CLN6ENSG00000128973.7673.72220404.948300.734308.049206.58140K562MAGOH
CLN6ENSG00000128973.7622.20350404.078500.622705.892204.47430K562MATR3
CLN6ENSG00000128973.7209.11450291.12410-0.477302.155401.38230K562METAP2
CLN6ENSG00000128973.7382.51010651.36460-0.7680010.240408.78720K562MTPAP
CLN6ENSG00000128973.7414.61160581.29280-0.487502.434301.61840K562NAA15
CLN6ENSG00000128973.7508.73700723.69510-0.508506.386805.31600K562NSUN2
CLN6ENSG00000128973.7459.45690773.16720-0.750906.834305.52600K562PCBP3
CLN6ENSG00000128973.7386.06280593.03800-0.619305.715404.56630K562POLR2G
CLN6ENSG00000128973.7847.28160393.456301.1065019.5262017.83870K562PTBP1
CLN6ENSG00000128973.7522.71080691.83750-0.404402.503701.98110K562PUS1
CLN6ENSG00000128973.7602.71600377.104200.676403.553102.59360K562RBM22
CLN6ENSG00000128973.7268.26160386.75740-0.527803.849201.99530K562RPS10
CLN6ENSG00000128973.7335.61970215.077500.641902.960601.92190K562RPS3
CLN6ENSG00000128973.7703.11600528.435100.411902.962801.84380K562SAFB
CLN6ENSG00000128973.7556.46500262.404301.084404.998503.04110K562SFPQ
CLN6ENSG00000128973.7233.91820360.57110-0.624303.967101.97170K562SND1
CLN6ENSG00000128973.7469.77320344.748600.446302.500501.53710K562SRFBP1
CLN6ENSG00000128973.7757.46920385.754000.973407.536606.37770K562SRSF1
CLN6ENSG00000128973.7432.96120624.81890-0.529205.370703.71980K562SRSF7
CLN6ENSG00000128973.7278.07670405.05150-0.542603.752602.23200K562SSB
CLN6ENSG00000128973.7869.70230594.843100.547905.793604.59840K562SYNCRIP
CLN6ENSG00000128973.789.14490201.77190-1.178505.151202.90190K562TAF15
CLN6ENSG00000128973.7528.54600390.331400.437202.656101.96100K562TARDBP
CLN6ENSG00000128973.7597.02030376.538900.664906.377205.06010K562TIA1
CLN6ENSG00000128973.7529.47700369.678500.518203.575602.30250K562TRA2A
CLN6ENSG00000128973.7470.28030656.59470-0.481503.910802.86380K562WDR3
CLN6ENSG00000128973.7750.650301181.29480-0.654205.172003.93230K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CLN6 is not available on ENCORE database.





8 RBPs can affect the splicing of CLN6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECLN6ENSG00000128973.7chr15-685019746850209768499329685007486851087368510988-0.158000.000060.00167excludedK562PUS1
SECLN6ENSG00000128973.7chr15-6850197468502097684993296850074868510873685109880.166000.000540.01555includedHepG2SRSF1
A5SSCLN6ENSG00000128973.7chr15-6850389368504201685040126850420168503600685036560.249000.000850.01628longerK562AQR
MXECLN6ENSG00000128973.7chr15-68503600685036566851087368510988685019746850209768521839685220560.153000.006190.080891includedK562PUS1
MXECLN6ENSG00000128973.7chr15-68506627685067266851087368510988685040126850420168521839685220800.130000.000780.027341includedK562XRN2
MXECLN6ENSG00000128973.7chr15-6850401268504201685066276850672668503600685036566851087368510988-0.129000.000950.094072includedK562UTP3
MXECLN6ENSG00000128973.7chr15-6850662768506726685108736851098868504012685042016852183968522080-0.157000.001470.055422includedK562FXR1
MXECLN6ENSG00000128973.7chr15-68504012685042016850662768506726685036006850365668510873685109880.185000.001720.038331includedHepG2DDX55
MXECLN6ENSG00000128973.7chr15-6850662768506726685108736851098868504012685042016852183968522080-0.216000.000500.085392includedK562NCBP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CLN6 is not avaliable on ENCORE database.