CDC7

General Information

Gene Name       : CDC7
Gene ID             : ENSG00000097046.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CDC7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CDC7ENSG00000097046.1224.3919.3021.84ENCSR000AEF
HepG2CDC7ENSG00000097046.125.2010.687.94ENCSR985KAT
K562CDC7ENSG00000097046.1226.7732.4229.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CDC7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CDC7 RNA is bound by 12 proteins.  







eCLIP assay for CDC7 is not avaliable on ENCORE database.





12 proteins are bound to CDC7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19199082991990878+3'-UTR3.753556.89197K562PUM2
chr19196644291966485+5'-UTR3.8713728.40011HepG2HNRNPM
chr19196719991967273+5'-UTR,intron-Proximal3.8366916.81927HepG2MATR3
chr19196674491966794+5'-UTR,intron-Distal3.2585518.61531HepG2SUGP2
chr19196666091966737+5'-UTR,intron-Distal5.8918225.58027HepG2MATR3
chr19196675991966839+5'-UTR,intron-Distal3.623934.86294HepG2PTBP1
chr19196642291966499+5'-UTR3.7122937.33070HepG2SUGP2
chr19196679691966838+5'-UTR,intron-Distal3.9317313.42814HepG2MATR3
chr19196725891967308+5'-UTR,CDS3.0825411.77312HepG2HNRNPM
chr19196717491967258+5'-UTR,intron-Proximal3.7202340.10205HepG2SUGP2
chr19196725891967309+5'-UTR,CDS3.1695117.21169HepG2SUGP2
chr19196674891966796+5'-UTR,intron-Distal5.0602721.06088HepG2MATR3
chr19196642591966505+5'-UTR4.352675.47892K562DDX3X
chr19196640991966442+5'-UTR4.6124829.59589HepG2MATR3
chr19196679491966848+5'-UTR,intron-Distal3.6355323.54969HepG2SUGP2
chr19196669891966749+5'-UTR,intron-Distal3.1325814.21182HepG2XPO5
chr19196644291966482+5'-UTR4.1344420.51817HepG2MATR3
chr19196736691967447+CDS,intron-Proximal4.557919.12083K562PRPF8
chr19197339391973432+CDS,intron-Distal,intron-Proximal3.786894.79983HepG2U2AF2
chr19196801191968071+intron-Distal3.2787314.09652HepG2MATR3
chr19196695391967013+intron-Distal,intron-Proximal4.9132622.29458HepG2MATR3
chr19196704591967099+intron-Distal,intron-Proximal4.7891822.01236HepG2SUGP2
chr19196749891967582+intron-Distal3.531855.56048K562KHSRP
chr19196825391968322+intron-Distal4.2961617.03528HepG2MATR3
chr19196810191968172+intron-Distal3.2630218.27802HepG2SUGP2
chr19196948191969510+intron-Distal3.697924.93809HepG2HNRNPC
chr19196843291968542+intron-Distal3.9689425.03869HepG2MATR3
chr19196856391968630+intron-Distal3.2023617.41808HepG2MATR3
chr19197033591970457+intron-Distal3.694063.02234K562KHSRP
chr19196687791966953+intron-Distal,intron-Proximal3.6121124.78283HepG2MATR3
chr19196833691968410+intron-Distal3.5106222.77386HepG2MATR3
chr19196706991967106+intron-Distal,intron-Proximal3.8339112.97326HepG2HNRNPM
chr19198466991984759+intron-Distal3.795693.55315K562SAFB
chr19196848791968568+intron-Distal3.875843.23532K562MATR3
chr19196864391968688+intron-Distal4.363258.93039HepG2HNRNPM
chr19196656691966662+intron-Distal,intron-Proximal3.3441141.00286HepG2SUGP2
chr19196656091966660+intron-Distal,intron-Proximal4.9780539.04998HepG2MATR3
chr19196810791968137+intron-Distal3.542927.30415HepG2MATR3
chr19197313491973278+intron-Distal3.039015.34873K562KHSRP
chr19196712591967174+intron-Proximal3.8680515.04963HepG2SUGP2
chr19196712391967134+intron-Proximal5.2689754.43207HepG2HNRNPM
chr19196650591966566+intron-Proximal3.8688122.50048HepG2SUGP2
chr19196714691967190+intron-Proximal4.2341612.52371HepG2MATR3
chr19196651491966557+intron-Proximal5.3191915.50794HepG2MATR3
chr19196713491967180+intron-Proximal4.8778661.32408HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CDC7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CDC7 is not available on ENCORE database.

  • 107 RBPs can affect the levels of CDC7.  








The Knockdown/knockout RNA-Seq assay for CDC7 is not available on ENCORE database.





107 RBPs can affect the gene expression of CDC7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CDC7ENSG00000097046.8137.03290216.57440-0.660302.502601.76910HepG2AKAP8L
CDC7ENSG00000097046.856.11090124.10510-1.145204.291803.32260HepG2ASCC1
CDC7ENSG00000097046.8123.91600219.76350-0.826603.338902.35320HepG2BCLAF1
CDC7ENSG00000097046.8150.97180358.61900-1.2482011.4880010.38030HepG2BOP1
CDC7ENSG00000097046.8194.27880293.53010-0.595403.371102.53030HepG2CALR
CDC7ENSG00000097046.8169.68970329.22830-0.956206.707905.67330HepG2CPSF6
CDC7ENSG00000097046.8211.20840293.55380-0.475002.840602.19060HepG2CELF1
CDC7ENSG00000097046.8218.10050315.74660-0.533803.387302.58230HepG2DAZAP1
CDC7ENSG00000097046.8102.05140248.61760-1.284607.098005.92910HepG2DDX55
CDC7ENSG00000097046.854.17730123.40940-1.187704.397403.63290HepG2DDX6
CDC7ENSG00000097046.8131.25560194.72670-0.569102.863602.20230HepG2DNAJC2
CDC7ENSG00000097046.8106.42950183.67380-0.787203.247502.03810HepG2AGO1
CDC7ENSG00000097046.872.20970118.65410-0.716502.032301.51480HepG2EIF2S1
CDC7ENSG00000097046.8190.04760298.33040-0.650603.907702.94940HepG2EIF4G2
CDC7ENSG00000097046.8161.54550344.05110-1.0907010.631109.57750HepG2ETF1
CDC7ENSG00000097046.8227.12170132.284200.779703.657302.86990HepG2FXR1
CDC7ENSG00000097046.8204.02700373.19660-0.871205.683804.78780HepG2GPKOW
CDC7ENSG00000097046.8133.30830198.36420-0.573402.181201.60180HepG2HNRNPA1
CDC7ENSG00000097046.8184.45120290.12990-0.653503.161702.17130HepG2HNRNPA2B1
CDC7ENSG00000097046.8147.15300220.63680-0.584402.343001.70000HepG2HNRNPC
CDC7ENSG00000097046.8163.13930262.50140-0.686204.305003.43130HepG2HNRNPF
CDC7ENSG00000097046.8210.16560287.65260-0.452802.570201.91910HepG2HNRNPL
CDC7ENSG00000097046.8136.80680356.14920-1.3803012.2432011.04000HepG2HNRNPLL
CDC7ENSG00000097046.8139.41290258.49050-0.890705.856004.84270HepG2IGF2BP1
CDC7ENSG00000097046.8194.74220132.330200.557301.954301.39890HepG2MAGOH
CDC7ENSG00000097046.8285.47900133.075101.101006.733505.78310HepG2MATR3
CDC7ENSG00000097046.8238.52250363.24640-0.606802.664301.71620HepG2MTPAP
CDC7ENSG00000097046.8142.23110232.21180-0.707202.985801.90800HepG2PCBP2
CDC7ENSG00000097046.8392.92680244.114100.686603.407402.06540HepG2PRPF6
CDC7ENSG00000097046.882.96310191.87480-1.209605.787104.66700HepG2PRPF8
CDC7ENSG00000097046.8121.17480298.84110-1.302308.627607.65100HepG2PUF60
CDC7ENSG00000097046.8231.51380316.98850-0.453302.625901.97160HepG2PUM2
CDC7ENSG00000097046.8147.35100287.56520-0.964607.436306.68330HepG2RBM22
CDC7ENSG00000097046.8243.05150142.709900.768104.432603.77670HepG2NELFE
CDC7ENSG00000097046.8232.26500132.924700.805104.798804.01660HepG2RECQL
CDC7ENSG00000097046.8117.01580282.75620-1.2729010.025208.86240HepG2RPLP0
CDC7ENSG00000097046.8127.99240220.11960-0.782203.263502.23740HepG2RPS10
CDC7ENSG00000097046.8112.11530177.26930-0.661002.845802.22350HepG2RPS19
CDC7ENSG00000097046.8144.54640230.75570-0.674803.023702.18700HepG2RPS2
CDC7ENSG00000097046.874.05860189.81240-1.357806.560405.40570HepG2RRP9
CDC7ENSG00000097046.8227.48000352.51200-0.631903.791002.97620HepG2SF3B1
CDC7ENSG00000097046.8195.30180133.499400.548802.302101.75600HepG2SF3B4
CDC7ENSG00000097046.8213.97720286.47250-0.420902.525601.85110HepG2SLBP
CDC7ENSG00000097046.8153.63570392.23330-1.352209.391907.95960HepG2SNRNP70
CDC7ENSG00000097046.8210.67420324.79820-0.624504.169503.59130HepG2SRFBP1
CDC7ENSG00000097046.8311.31900139.349301.1596010.443709.65540HepG2SRSF1
CDC7ENSG00000097046.8223.25540295.02150-0.402102.326301.74660HepG2SRSF5
CDC7ENSG00000097046.8115.78500257.89390-1.155309.718008.54900HepG2SRSF7
CDC7ENSG00000097046.899.24450247.52000-1.318507.284906.27080HepG2SUPV3L1
CDC7ENSG00000097046.8228.42430125.265800.866605.336804.60040HepG2TAF15
CDC7ENSG00000097046.8185.55150347.16010-0.903806.533605.48210HepG2TARDBP
CDC7ENSG00000097046.885.73010165.91930-0.952603.625602.50360HepG2TFIP11
CDC7ENSG00000097046.895.53370212.99830-1.156807.978407.20960HepG2TIAL1
CDC7ENSG00000097046.8127.23990214.87510-0.755904.636003.94370HepG2TRIM56
CDC7ENSG00000097046.8217.66580291.89980-0.423402.134501.37430HepG2TUFM
CDC7ENSG00000097046.8208.96510308.93500-0.564002.386001.61240HepG2UBE2L3
CDC7ENSG00000097046.8132.59420251.06480-0.921006.938305.91520HepG2UPF1
CDC7ENSG00000097046.8368.79090242.395400.605304.422603.69380HepG2UTP3
CDC7ENSG00000097046.8149.82260276.12530-0.882107.475806.68980HepG2ZNF622
CDC7ENSG00000097046.81715.018502255.77870-0.395406.614305.79180K562AGGF1
CDC7ENSG00000097046.81817.329402478.74930-0.447804.990803.57670K562AKAP8
CDC7ENSG00000097046.81461.749802347.23740-0.683309.524308.22450K562AKAP8L
CDC7ENSG00000097046.81284.412002587.78410-1.0106019.9790018.57210K562AQR
CDC7ENSG00000097046.82076.740902462.81220-0.246002.505201.63900K562ATP5C1
CDC7ENSG00000097046.81282.664901556.99390-0.279603.449002.37220K562BCLAF1
CDC7ENSG00000097046.81571.892002212.67680-0.493304.366703.26350K562BOP1
CDC7ENSG00000097046.81780.178002333.44230-0.390403.089101.56890K562BUD13
CDC7ENSG00000097046.82286.468903174.64920-0.473502.399801.42150K562CNOT7
CDC7ENSG00000097046.82357.508403110.82730-0.400006.667804.91240K562CPEB4
CDC7ENSG00000097046.81357.323402352.78920-0.793608.327306.95470K562CPSF6
CDC7ENSG00000097046.8727.735701223.42540-0.7494011.518709.24000K562DDX3X
CDC7ENSG00000097046.82825.138203219.19790-0.188402.032301.45920K562DDX47
CDC7ENSG00000097046.8898.114701240.36690-0.465806.102703.91530K562DDX6
CDC7ENSG00000097046.8780.245901267.69250-0.700207.891006.28040K562EFTUD2
CDC7ENSG00000097046.81030.576201343.72140-0.382805.083803.41940K562EIF2S1
CDC7ENSG00000097046.81432.743502127.34030-0.570309.355808.15200K562EIF2S2
CDC7ENSG00000097046.81012.364901357.52830-0.423302.620001.61550K562EIF3D
CDC7ENSG00000097046.81156.039401366.40300-0.241202.234501.51340K562EIF3G
CDC7ENSG00000097046.8832.484901278.13810-0.618507.531706.18010K562EIF4A3
CDC7ENSG00000097046.8930.597001150.99490-0.306702.863101.68280K562EIF4B
CDC7ENSG00000097046.8903.006901115.65930-0.305102.572601.33010K562EWSR1
CDC7ENSG00000097046.81723.829902408.09390-0.482305.524904.30270K562FIP1L1
CDC7ENSG00000097046.81702.298502393.75430-0.491803.710602.71630K562FMR1
CDC7ENSG00000097046.81559.489402028.85630-0.379603.023902.06340K562FTO
CDC7ENSG00000097046.82098.354801610.845000.381302.310001.67180K562G3BP2
CDC7ENSG00000097046.81261.358902246.39790-0.8326011.367309.73370K562GPKOW
CDC7ENSG00000097046.81462.570302835.11640-0.9549014.0277012.30270K562GRSF1
CDC7ENSG00000097046.8829.217601728.97410-1.0601018.9117017.42790K562HNRNPC
CDC7ENSG00000097046.82496.925501713.284700.543305.799703.94350K562HNRNPK
CDC7ENSG00000097046.82364.981103264.90560-0.465205.367904.27580K562HSPD1
CDC7ENSG00000097046.81312.527101714.60530-0.385502.450701.50230K562IGF2BP2
CDC7ENSG00000097046.81275.069901744.25240-0.452003.300901.96680K562IGF2BP3
CDC7ENSG00000097046.82102.925602491.01460-0.244302.142401.42650K562KIF1C
CDC7ENSG00000097046.8994.255601917.97800-0.9479010.713708.75500K562KRR1
CDC7ENSG00000097046.81888.490602384.50660-0.336502.993501.86500K562MAK16
CDC7ENSG00000097046.82320.392302790.56430-0.266202.220801.42110K562MBNL1
CDC7ENSG00000097046.81303.152702192.70830-0.750708.071106.53140K562METAP2
CDC7ENSG00000097046.81274.190902124.40170-0.7375021.0843019.15450K562MTPAP
CDC7ENSG00000097046.8930.315901248.56730-0.424503.007001.64120K562NONO
CDC7ENSG00000097046.81994.403602360.38990-0.243104.173203.27800K562NSUN2
CDC7ENSG00000097046.81847.192402733.62030-0.565507.170105.73070K562PPIG
CDC7ENSG00000097046.8948.227301233.60530-0.379602.598301.87130K562PRPF8
CDC7ENSG00000097046.81200.646001550.14720-0.368602.259901.45060K562PSIP1
CDC7ENSG00000097046.81426.870301751.33060-0.295602.021701.43710K562PTBP1
CDC7ENSG00000097046.82483.399803926.39990-0.660907.778506.40440K562PUF60
CDC7ENSG00000097046.83187.020104091.99570-0.360605.765304.36160K562PUM2
CDC7ENSG00000097046.81500.244402327.83410-0.633806.368905.58390K562PUS1
CDC7ENSG00000097046.81837.794902268.10820-0.303502.557401.98420K562RBM15
CDC7ENSG00000097046.81115.761401679.67720-0.590205.989504.69250K562RBM22
CDC7ENSG00000097046.81180.395801528.74670-0.373103.429201.93490K562RBM25
CDC7ENSG00000097046.81164.542401414.02310-0.280002.248701.35920K562RCC2
CDC7ENSG00000097046.81216.162701636.67570-0.428403.648101.67910K562RECQL
CDC7ENSG00000097046.8647.660601256.72080-0.9564011.261509.58350K562RPS19
CDC7ENSG00000097046.8980.594501919.08630-0.968704.595102.92450K562SF1
CDC7ENSG00000097046.81956.391002329.11900-0.251602.896102.06520K562SF3A3
CDC7ENSG00000097046.81254.572101675.80250-0.417704.421303.32940K562SF3B4
CDC7ENSG00000097046.8916.000701340.48570-0.549305.760804.13070K562SRFBP1
CDC7ENSG00000097046.8581.074301716.81390-1.5629034.7843032.31960K562SRSF1
CDC7ENSG00000097046.81112.984501621.21810-0.542604.924503.44830K562SRSF5
CDC7ENSG00000097046.8859.295101194.67360-0.475403.311602.19260K562SUPV3L1
CDC7ENSG00000097046.81741.033701410.637600.303502.938202.09070K562SYNCRIP
CDC7ENSG00000097046.81080.471901737.68720-0.685505.990404.92100K562TARDBP
CDC7ENSG00000097046.8998.720001676.15360-0.7470011.9080010.09810K562TIA1
CDC7ENSG00000097046.81158.638801491.01700-0.363902.184501.36260K562TIAL1
CDC7ENSG00000097046.81302.758601644.42750-0.336002.742001.65570K562TRA2A
CDC7ENSG00000097046.81216.716001583.69430-0.380303.383302.31820K562TRIM56
CDC7ENSG00000097046.82024.753301613.260100.327703.548602.63850K562U2AF2
CDC7ENSG00000097046.81770.208302502.77240-0.4996011.4441010.10790K562UPF1
CDC7ENSG00000097046.81617.015302360.16230-0.545602.581601.34940K562UTP18
CDC7ENSG00000097046.82063.821002711.36360-0.393702.985401.73390K562UTP3
CDC7ENSG00000097046.8979.118101287.16800-0.394602.792301.57980K562XRN2
CDC7ENSG00000097046.82227.387002915.21900-0.388304.122803.03380K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CDC7 is not available on ENCORE database.





11 RBPs can affect the splicing of CDC7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECDC7ENSG00000097046.8chr1+9197065191970746919672109196738891973410919734940.054000.000770.01687includedK562SRSF1
SECDC7ENSG00000097046.8chr1+919786149197886491977337919774809197950491979600-0.317000.000000.00013excludedK562SRSF1
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.057000.006970.09824excludedK562SRSF1
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.124000.000070.01063excludedK562XRCC6
SECDC7ENSG00000097046.8chr1+919771309197724791973818919739549197733791977380-0.055000.006460.05744excludedK562AQR
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.097000.000130.00424excludedK562U2AF1
SECDC7ENSG00000097046.8chr1+9197950491979600919786149197886491980375919805540.196000.002160.04650includedHepG2SRSF1
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.077000.000000.00007excludedK562HNRNPUL1
SECDC7ENSG00000097046.8chr1+919795049197960091978614919788649198037591980554-0.183000.000040.00144excludedK562U2AF2
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.075000.000530.01190excludedK562U2AF2
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.079000.001540.05240excludedK562TARDBP
SECDC7ENSG00000097046.8chr1+919795049197960091978614919788649198037591980554-0.099000.003320.06727excludedK562RBM15
SECDC7ENSG00000097046.8chr1+919672109196738891966449919665059197341091973494-0.092000.000280.01510excludedK562PTBP1
A3SSCDC7ENSG00000097046.8chr1+9196719391967388919672109196738891966449919665050.087000.000640.00467longerK562AQR
A3SSCDC7ENSG00000097046.8chr1+9198035191980554919803759198055491979504919796000.174000.000000.00000longerK562AQR
A3SSCDC7ENSG00000097046.8chr1+919672109196738891967327919673889196640791966505-0.242000.000650.05623shorterK562SRSF1
MXECDC7ENSG00000097046.8chr1+9196721091967388919734109197349491966449919665059197381891973954-0.175000.001200.023402includedK562PUS1
MXECDC7ENSG00000097046.8chr1+9198135091981433919856869198583691980375919805549198959791990056-0.137000.002410.090242includedK562UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CDC7 is not avaliable on ENCORE database.