CD53

General Information

Gene Name       : CD53
Gene ID             : ENSG00000143119.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CD53)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CD53ENSG00000143119.13469.33440.27454.80ENCSR000AEF
HepG2CD53ENSG00000143119.130.000.000.00ENCSR985KAT
K562CD53ENSG00000143119.1387.5587.9387.74ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CD53 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CD53 RNA is bound by 10 proteins.  







eCLIP assay for CD53 is not avaliable on ENCORE database.





10 proteins are bound to CD53 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1111442399111442460+3'-UTR3.843438.04470K562IGF2BP1
chr1111441940111442005+3'-UTR3.008266.43036K562IGF2BP2
chr1111442005111442056+3'-UTR4.396347.51369K562IGF2BP2
chr1111442273111442315+3'-UTR3.178535.67309K562IGF2BP1
chr1111442004111442056+3'-UTR3.583019.91125K562IGF2BP1
chr1111442250111442273+3'-UTR3.152173.66454K562IGF2BP1
chr1111442084111442130+3'-UTR5.060967.13565K562IGF2BP1
chr1111441838111441932+3'-UTR3.523584.01163K562RBM15
chr1111442139111442208+3'-UTR4.740489.66769K562IGF2BP1
chr1111415784111415834+5'-UTR3.824807.98234K562DDX3X
chr1111434083111434148+CDS,intron-Proximal3.6081620.33657K562PRPF8
chr1111434091111434135+CDS,intron-Proximal3.986074.15711K562AQR
chr1111440496111440514+CDS,intron-Distal4.4734911.28118K562SND1
chr1111435074111435143+CDS4.0324115.66886K562SND1
chr1111437676111437729+CDS,intron-Distal,intron-Proximal4.385417.53589K562AQR
chr1111440434111440448+CDS,intron-Distal3.750566.57858K562SND1
chr1111440460111440496+CDS,intron-Distal4.6489113.39409K562SND1
chr1111434968111434993+CDS3.088475.91432K562SND1
chr1111439288111439352+CDS,intron-Distal4.5874818.59539K562SND1
chr1111439276111439284+CDS,intron-Distal4.524158.62767K562SND1
chr1111436949111437010+CDS,intron-Distal4.2291622.66486K562SND1
chr1111441745111441787+CDS,intron-Proximal3.8113312.57125K562SND1
chr1111435154111435201+CDS,intron-Proximal4.662633.62536K562AQR
chr1111437636111437671+CDS,intron-Distal3.8728110.48685K562SND1
chr1111437010111437022+CDS,intron-Distal4.927587.95584K562SND1
chr1111437582111437636+CDS,intron-Distal3.7842313.86742K562SND1
chr1111437671111437677+CDS,intron-Distal4.498059.24069K562SND1
chr1111440931111440938+intron-Distal4.661854.96452K562YBX3
chr1111437199111437264+intron-Distal5.431329.16624K562TARDBP
chr1111438118111438187+intron-Distal4.425905.66159K562LIN28B
chr1111440861111440931+intron-Distal3.469027.42315K562YBX3
chr1111437275111437347+intron-Distal5.317417.26804K562TARDBP
chr1111437533111437582+intron-Distal,intron-Proximal3.839456.79537K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CD53 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CD53 is not available on ENCORE database.

  • 85 RBPs can affect the levels of CD53.  








The Knockdown/knockout RNA-Seq assay for CD53 is not available on ENCORE database.





85 RBPs can affect the gene expression of CD53 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CD53ENSG00000143119.8617.52840979.78160-0.666007.585105.58990K562AARS
CD53ENSG00000143119.8992.852401254.76970-0.337803.785201.99350K562AKAP1
CD53ENSG00000143119.81418.103801919.09980-0.436504.018702.47970K562APOBEC3C
CD53ENSG00000143119.8590.354601252.49130-1.085109.900308.89450K562AQR
CD53ENSG00000143119.82171.097401483.718100.549107.735404.65050K562AUH
CD53ENSG00000143119.8984.934201278.99580-0.376902.728801.42890K562BCCIP
CD53ENSG00000143119.81978.44820887.382701.1566022.0810019.67820K562BOP1
CD53ENSG00000143119.81342.00940800.331200.745604.140402.34100K562BUD13
CD53ENSG00000143119.81529.571601212.341000.335203.197501.91680K562CCDC124
CD53ENSG00000143119.81538.259801011.255100.605102.274001.32860K562CNOT7
CD53ENSG00000143119.82100.586101304.940500.6867016.3253013.75310K562CPEB4
CD53ENSG00000143119.81307.66700943.467100.470903.912902.98090K562CPSF6
CD53ENSG00000143119.8747.34080937.55520-0.327102.428501.44700K562CSTF2
CD53ENSG00000143119.81726.364402673.97730-0.6313011.577909.66470K562CELF1
CD53ENSG00000143119.81718.317801271.336500.434604.827203.39900K562DDX3X
CD53ENSG00000143119.81085.847901350.50820-0.314703.697102.95860K562DDX47
CD53ENSG00000143119.8505.099001066.98050-1.0789011.965509.51680K562EEF2
CD53ENSG00000143119.82210.298701000.801201.1430030.2220028.30840K562EIF2S2
CD53ENSG00000143119.8648.589601062.35680-0.7119010.996009.39620K562EIF3G
CD53ENSG00000143119.81329.22620917.663200.534404.246902.12170K562FAM120A
CD53ENSG00000143119.82082.59830960.101201.1170018.1098015.84830K562FMR1
CD53ENSG00000143119.81593.44340813.835700.9692014.2152012.00710K562FTO
CD53ENSG00000143119.81175.94880939.210500.324202.685701.36840K562FUS
CD53ENSG00000143119.8415.030901381.26350-1.7347063.3481060.72570K562FXR1
CD53ENSG00000143119.8794.621801005.56140-0.339703.152001.93140K562GLRX3
CD53ENSG00000143119.81690.89430900.718600.9085016.0165014.06330K562GPKOW
CD53ENSG00000143119.8797.677301437.07620-0.8493015.1780012.97830K562HNRNPA1
CD53ENSG00000143119.8824.470201071.81700-0.378503.144202.51340K562HNRNPC
CD53ENSG00000143119.8553.52480792.83540-0.518404.750402.30380K562HNRNPH1
CD53ENSG00000143119.81867.694701220.433300.613804.687703.27190K562HNRNPL
CD53ENSG00000143119.8888.736801591.47310-0.8405018.3766016.18320K562HNRNPU
CD53ENSG00000143119.81163.833801650.82360-0.504304.243801.84900K562KHSRP
CD53ENSG00000143119.83131.508102505.198600.321804.050701.66980K562CCAR2
CD53ENSG00000143119.81180.27560769.259400.617503.321102.28910K562KRR1
CD53ENSG00000143119.8685.869101087.31070-0.664806.555004.14120K562LIN28B
CD53ENSG00000143119.8655.217301715.90680-1.3889037.2182033.92220K562MAGOH
CD53ENSG00000143119.8736.989001712.42140-1.2163030.5197027.52150K562MATR3
CD53ENSG00000143119.81354.27160879.227300.623107.949606.42210K562METAP2
CD53ENSG00000143119.8845.361701057.20890-0.322603.420402.52590K562MTPAP
CD53ENSG00000143119.81890.022601326.333200.510907.133105.19230K562NCBP2
CD53ENSG00000143119.81443.882501174.697700.297604.181203.28480K562NSUN2
CD53ENSG00000143119.81057.362801677.30730-0.6657010.781808.13280K562PCBP1
CD53ENSG00000143119.8876.234601526.72700-0.8011012.4371010.28360K562PCBP2
CD53ENSG00000143119.8284.78250958.41990-1.7508031.9526029.38690K562PCBP3
CD53ENSG00000143119.81771.131202234.74070-0.335403.245301.69470K562PNPT1
CD53ENSG00000143119.8181.67060735.14120-2.0167046.1736043.41800K562POLR2G
CD53ENSG00000143119.81532.71720937.883700.708504.255403.20760K562PPIG
CD53ENSG00000143119.8394.102401003.24030-1.3480022.1599020.03470K562PRPF8
CD53ENSG00000143119.81138.162601667.11300-0.550607.661306.59270K562PTBP1
CD53ENSG00000143119.81206.026702372.97960-0.9764018.9714016.76240K562PUF60
CD53ENSG00000143119.83844.561002523.854600.6071013.0844010.70930K562PUM1
CD53ENSG00000143119.84841.547502473.063100.9691038.5056035.43950K562PUM2
CD53ENSG00000143119.81750.286301046.895600.741404.082803.44210K562PUS1
CD53ENSG00000143119.81035.306301598.54690-0.626707.936206.41630K562RBM22
CD53ENSG00000143119.8790.306401046.32480-0.404804.063802.15840K562RPS10
CD53ENSG00000143119.8604.232901021.97030-0.758206.877405.57730K562RPS19
CD53ENSG00000143119.8633.94510906.34600-0.515703.861902.65470K562RPS3
CD53ENSG00000143119.8535.234201025.83370-0.938608.695406.40910K562RRP9
CD53ENSG00000143119.8186.84580655.02720-1.8097032.3704029.55610K562SAFB
CD53ENSG00000143119.8324.28760677.22270-1.0624013.3296010.47270K562SDAD1
CD53ENSG00000143119.8333.29470858.53790-1.3651010.122807.47100K562SERBP1
CD53ENSG00000143119.81748.877801159.062000.5934010.820509.28100K562SF3A3
CD53ENSG00000143119.8609.988601528.27780-1.3251037.1540033.74880K562SF3B4
CD53ENSG00000143119.8654.48640831.32600-0.345102.291701.37680K562SRFBP1
CD53ENSG00000143119.8659.469101187.47810-0.8485020.7962018.60140K562SRPK2
CD53ENSG00000143119.81051.991701634.32970-0.635609.419308.12440K562SRSF1
CD53ENSG00000143119.8692.37300874.93420-0.337602.369601.40610K562SRSF4
CD53ENSG00000143119.8400.18620836.76890-1.0642018.6833015.14260K562SRSF9
CD53ENSG00000143119.81389.627301095.837500.342603.777302.24850K562SSB
CD53ENSG00000143119.8240.64740737.36520-1.6155033.0458030.57040K562SYNCRIP
CD53ENSG00000143119.81203.188601654.04150-0.459104.295103.40690K562TARDBP
CD53ENSG00000143119.81032.660001595.51160-0.627709.207007.59920K562TIA1
CD53ENSG00000143119.81114.110801565.68760-0.490905.095803.52340K562TRA2A
CD53ENSG00000143119.8373.14060696.78670-0.901007.986705.09600K562TRNAU1AP
CD53ENSG00000143119.81002.164201424.69560-0.507504.105702.71540K562U2AF1
CD53ENSG00000143119.81168.844201471.33620-0.332003.184702.32430K562U2AF2
CD53ENSG00000143119.85353.700702675.328901.0007028.5257025.17880K562UBE2L3
CD53ENSG00000143119.81348.757601028.115000.391503.095402.01340K562UCHL5
CD53ENSG00000143119.83651.890701245.553401.55180100.7059097.62040K562UPF1
CD53ENSG00000143119.81101.014601525.39830-0.470405.408903.07600K562UPF2
CD53ENSG00000143119.81379.269301065.786400.371902.842301.95380K562WDR3
CD53ENSG00000143119.8515.919301108.25540-1.1031031.5270029.23150K562WDR43
CD53ENSG00000143119.81317.18250609.785801.111006.294103.63470K562XPO5
CD53ENSG00000143119.82396.782201410.714800.7646010.575708.76040K562ZC3H8
CD53ENSG00000143119.8464.46180784.03930-0.755409.436906.31260K562ZNF800
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CD53 is not available on ENCORE database.





17 RBPs can affect the splicing of CD53 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECD53ENSG00000143119.8chr1+111440430111440514111437581111437677111441745111442550-0.286000.000030.00116excludedK562SF3B4
SECD53ENSG00000143119.8chr1+111436948111437023111434966111435155111441745111442550-0.188000.000670.02765excludedK562PRPF8
SECD53ENSG00000143119.8chr1+111440430111440514111437581111437677111441745111442198-0.270000.000000.00034excludedK562AKAP8L
SECD53ENSG00000143119.8chr1+111436948111437023111434966111435155111441745111442550-0.227000.000000.00001excludedK562PUS1
SECD53ENSG00000143119.8chr1+111436948111437023111434966111435155111441745111442550-0.134000.001630.07294excludedK562EFTUD2
SECD53ENSG00000143119.8chr1+1114375811114376771114349661114351551114417451114424730.469000.000010.00034includedK562U2AF1
SECD53ENSG00000143119.8chr1+111440430111440514111437581111437677111441745111442198-0.185000.000630.01551excludedK562U2AF1
SECD53ENSG00000143119.8chr1+111440430111440514111437581111437677111441745111442198-0.164000.000210.02233excludedK562HNRNPUL1
SECD53ENSG00000143119.8chr1+111436948111437023111434966111435155111441745111442550-0.171000.000430.01787excludedK562UTP18
SECD53ENSG00000143119.8chr1+1114375811114376771114349661114351551114417451114424730.474000.000000.00020includedK562U2AF2
SECD53ENSG00000143119.8chr1+111436948111437023111434966111435155111437581111437677-0.157000.000000.00000excludedK562U2AF2
SECD53ENSG00000143119.8chr1+111439274111439355111437581111437677111441745111442550-0.422000.000020.00069excludedK562U2AF2
SECD53ENSG00000143119.8chr1+111440430111440514111437581111437677111441745111442198-0.377000.000000.00000excludedK562RBM15
SECD53ENSG00000143119.8chr1+111436948111437023111434966111435155111441745111442198-0.160000.000630.01926excludedK562AGGF1
SECD53ENSG00000143119.8chr1+111434966111435155111434013111434093111441745111442136-0.057000.000690.03404excludedK562HNRNPK
SECD53ENSG00000143119.8chr1+111440430111440514111437581111437677111441745111442198-0.152000.000470.07445excludedK562NPM1
SECD53ENSG00000143119.8chr1+111440430111440514111439274111439355111441745111442198-0.110000.000130.00343excludedK562HNRNPC
A3SSCD53ENSG00000143119.8chr1+1114349411114351551114349661114351551114340131114340930.085000.000000.00000longerK562AQR
MXECD53ENSG00000143119.8chr1+111439274111439355111440430111440514111437581111437677111441745111442550-0.174000.000340.006812includedK562U2AF2
MXECD53ENSG00000143119.8chr1+1114340131114340931114349661114351551114157741114158701114369481114370230.122000.000040.004081includedK562TAF15
MXECD53ENSG00000143119.8chr1+111439274111439355111440430111440514111437581111437677111441745111442550-0.093000.001000.030942includedK562PPIL4
MXECD53ENSG00000143119.8chr1+1114392741114393551114404301114405141114375811114376771114417451114425500.101000.006140.071011includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CD53 is not avaliable on ENCORE database.