ZC3H4

General Information

Gene Name       : ZC3H4
Gene ID             : ENSG00000130749.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ZC3H4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ZC3H4ENSG00000130749.918.7926.3922.59ENCSR000AEF
HepG2ZC3H4ENSG00000130749.913.799.8811.84ENCSR985KAT
K562ZC3H4ENSG00000130749.924.2322.6723.45ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ZC3H4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ZC3H4 RNA is bound by 19 proteins.  







eCLIP assay for ZC3H4 is not avaliable on ENCORE database.





19 proteins are bound to ZC3H4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194756939247569457-3'-UTR,intron-Distal3.563633.88337HepG2FXR2
chr194756935747569458-3'-UTR,intron-Distal6.9423830.83659K562PUM2
chr194756935747569430-3'-UTR,intron-Distal5.185129.81732K562TIA1
chr194756749447567588-3'-UTR,intron-Distal5.3719022.08556K562PUM2
chr194756746847567546-3'-UTR,intron-Distal3.721623.07287K562TIA1
chr194756758847567671-3'-UTR,intron-Distal6.2133628.10411K562PUM2
chr194758839947588472-CDS,intron-Distal,intron-Proximal5.489366.41139HepG2EFTUD2
chr194757556147575618-CDS,intron-Distal,intron-Proximal4.027314.98250K562AQR
chr194759775847597839-CDS,intron-Distal,intron-Proximal4.7183210.38007K562UCHL5
chr194759717147597241-CDS,intron-Distal,intron-Proximal3.704036.65114HepG2PRPF8
chr194757228547572359-CDS,intron-Distal,intron-Proximal4.618604.48002K562AQR
chr194758823547588327-CDS,intron-Distal,intron-Proximal3.648764.98422K562PRPF8
chr194758857947588658-CDS,intron-Distal,intron-Proximal5.150356.81136K562ZNF622
chr194759724247597320-CDS,intron-Distal3.713114.49887K562ZNF622
chr194757045247570605-CDS,intron-Distal5.345384.97123HepG2PCBP2
chr194757106447571121-CDS,intron-Distal3.824693.11282HepG2G3BP1
chr194759721747597328-CDS,intron-Distal,intron-Proximal4.092496.15459HepG2GRWD1
chr194759783947597865-CDS,intron-Distal,intron-Proximal4.250033.01428K562UCHL5
chr194759776847597839-CDS,intron-Distal,intron-Proximal3.396927.91657HepG2PPIG
chr194758831247588377-CDS,intron-Distal,intron-Proximal3.086854.50547K562PUM1
chr194757498747575077-CDS,intron-Distal,intron-Proximal3.482528.98788HepG2PRPF8
chr194758864147588674-CDS,intron-Distal,intron-Proximal4.081106.21592K562PUM1
chr194759728947597332-CDS,intron-Distal4.492744.42734K562UCHL5
chr194758834647588414-CDS,intron-Distal,intron-Proximal5.129395.86954K562UCHL5
chr194759766947597756-CDS,intron-Distal,intron-Proximal3.282515.10493HepG2AQR
chr194759322347593324-CDS,intron-Distal,intron-Proximal5.5444311.02908K562UCHL5
chr194758766847587712-CDS,intron-Distal3.434833.95937K562UCHL5
chr194759327047593321-CDS,intron-Distal,intron-Proximal3.286365.28705K562PUM1
chr194757237147572448-CDS,intron-Distal4.812384.56100HepG2FXR2
chr194759341347593449-CDS,intron-Distal,intron-Proximal3.825643.18234K562BUD13
chr194759327547593318-CDS,intron-Distal,intron-Proximal3.302113.31745K562ZNF622
chr194759768747597759-CDS,intron-Distal,intron-Proximal4.354863.34184HepG2GRWD1
chr194759777447597867-CDS,intron-Distal,intron-Proximal3.831466.15582K562GRWD1
chr194758831147588346-CDS,intron-Distal,intron-Proximal3.693013.73423K562UCHL5
chr194759724747597336-CDS,intron-Distal3.013545.89894K562ZNF800
chr194757501247575036-CDS,intron-Distal,intron-Proximal3.842334.52312K562AQR
chr194758861747588672-CDS,intron-Distal,intron-Proximal3.360074.56136K562GRWD1
chr194759321947593307-CDS,intron-Distal,intron-Proximal3.277625.54641HepG2PPIG
chr194758831047588336-CDS,intron-Distal,intron-Proximal3.783793.12746HepG2GRWD1
chr194759322147593270-CDS,intron-Distal,intron-Proximal3.392924.14939K562PUM1
chr194759766247597805-CDS,intron-Distal,intron-Proximal4.518239.19326K562ZNF622
chr194758964047589690-CDS,intron-Distal,intron-Proximal4.756355.79198K562PUM1
chr194758859047588670-CDS,intron-Distal,intron-Proximal4.321407.16955K562UCHL5
chr194758958347589653-CDS,intron-Distal,intron-Proximal3.463793.96535HepG2AQR
chr194759322547593275-CDS,intron-Distal,intron-Proximal3.821185.47804K562ZNF622
chr194758825747588317-CDS,intron-Distal,intron-Proximal4.234824.89208K562AQR
chr194757513047575246-CDS,intron-Distal5.041526.56513K562FXR2
chr194757235047572394-CDS,intron-Distal4.161094.07072K562UCHL5
chr194758544047585489-CDS,intron-Distal,intron-Proximal4.342094.23295HepG2GRWD1
chr194758826947588332-CDS,intron-Distal,intron-Proximal3.588365.43815HepG2PRPF8
chr194761616447616242-intron-Distal3.618525.47443HepG2PCBP2
chr194760571947605912-intron-Distal5.372609.32107HepG2HNRNPM
chr194757912647579196-intron-Distal5.8929714.79964HepG2HNRNPM
chr194757950347579601-intron-Distal3.286385.09409K562TARDBP
chr194760069847600738-intron-Distal4.058413.07980HepG2HNRNPM
chr194757920447579235-intron-Distal4.522753.53404K562HNRNPM
chr194757914047579204-intron-Distal5.9605813.42189K562HNRNPM
chr194757919647579234-intron-Distal5.254578.05797HepG2HNRNPM
chr194757221747572285-intron-Distal,intron-Proximal3.623633.43550K562AQR
chr194757945647579538-intron-Distal3.716973.06347K562NONO
chr194760361347603731-intron-Distal4.552385.37406HepG2HNRNPM
chr194757498847575012-intron-Distal,intron-Proximal4.888895.65342K562AQR
chr194761419347614251-intron-Distal,intron-Proximal4.151576.65517HepG2U2AF2
chr194761112447611201-intron-Distal4.834686.95924HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ZC3H4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ZC3H4 is not available on ENCORE database.

  • 108 RBPs can affect the levels of ZC3H4.  








The Knockdown/knockout RNA-Seq assay for ZC3H4 is not available on ENCORE database.





108 RBPs can affect the gene expression of ZC3H4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ZC3H4ENSG00000130749.5834.80170692.416900.269702.356401.78820HepG2ACO1
ZC3H4ENSG00000130749.5795.955801004.98880-0.336403.150202.42400HepG2AUH
ZC3H4ENSG00000130749.5430.43170556.77060-0.371302.335701.62300HepG2CALR
ZC3H4ENSG00000130749.5852.39850692.275100.300102.958702.27580HepG2CKAP4
ZC3H4ENSG00000130749.5982.60560758.738900.372902.980401.83610HepG2CPSF7
ZC3H4ENSG00000130749.5431.43360329.002000.390902.534001.85640HepG2DNAJC21
ZC3H4ENSG00000130749.5437.50410326.141500.423703.402402.69270HepG2DNAJC2
ZC3H4ENSG00000130749.5748.18500439.464100.767506.807805.42730HepG2EEF2
ZC3H4ENSG00000130749.5708.01470504.957400.487502.847602.24670HepG2EIF2S1
ZC3H4ENSG00000130749.5880.69050698.903500.333402.448001.35120HepG2EIF2S2
ZC3H4ENSG00000130749.5884.72730557.943400.665005.209404.33400HepG2EIF4A3
ZC3H4ENSG00000130749.51015.64480543.415400.902204.776003.88790HepG2EIF4B
ZC3H4ENSG00000130749.5441.46370318.875600.469203.137401.88090HepG2FAM120A
ZC3H4ENSG00000130749.5850.46450563.225500.594404.779503.88590HepG2FXR1
ZC3H4ENSG00000130749.5750.30090522.324800.522403.528602.78180HepG2G3BP1
ZC3H4ENSG00000130749.5719.90820554.710000.376002.129101.35390HepG2G3BP2
ZC3H4ENSG00000130749.5564.41090369.475200.611202.596501.92260HepG2HNRNPC
ZC3H4ENSG00000130749.5755.57340530.039300.511406.857805.84060HepG2HNRNPL
ZC3H4ENSG00000130749.5575.63880367.031400.649203.699503.00850HepG2HNRNPU
ZC3H4ENSG00000130749.5755.66080530.878600.509303.473602.72520HepG2IGF2BP2
ZC3H4ENSG00000130749.5483.24260374.907900.366103.063902.29570HepG2ILF2
ZC3H4ENSG00000130749.5397.02290262.802100.595103.165201.87390HepG2KHDRBS1
ZC3H4ENSG00000130749.5561.60870387.353800.535803.544902.25850HepG2LARP7
ZC3H4ENSG00000130749.5972.02540563.423400.786708.037006.93100HepG2MAGOH
ZC3H4ENSG00000130749.5993.22210566.530600.809907.603106.59700HepG2MATR3
ZC3H4ENSG00000130749.5952.45540577.009200.723006.573305.40270HepG2NOL12
ZC3H4ENSG00000130749.5589.26840350.680000.748704.521702.70640HepG2NOLC1
ZC3H4ENSG00000130749.5483.99010252.034600.941305.480104.20150HepG2PABPC1
ZC3H4ENSG00000130749.5458.16780295.001500.635105.194403.53010HepG2PKM
ZC3H4ENSG00000130749.5475.06200327.360100.537104.544903.62220HepG2PPIL4
ZC3H4ENSG00000130749.5725.06190516.854900.488204.781804.10540HepG2PTBP1
ZC3H4ENSG00000130749.5808.20200550.825800.553005.397304.59990HepG2PUF60
ZC3H4ENSG00000130749.51002.05200584.749300.7770012.0767011.02170HepG2PUM1
ZC3H4ENSG00000130749.5877.65260584.307600.586805.529804.59580HepG2PUM2
ZC3H4ENSG00000130749.5562.77630335.040100.748103.937301.84410HepG2RBM14
ZC3H4ENSG00000130749.5769.66820467.101100.720406.044404.57180HepG2RBM27
ZC3H4ENSG00000130749.5914.58890575.209500.668909.448208.55670HepG2NELFE
ZC3H4ENSG00000130749.5696.86270535.730300.379303.212902.55510HepG2RECQL
ZC3H4ENSG00000130749.5584.53340738.30690-0.336902.188101.57150HepG2RPLP0
ZC3H4ENSG00000130749.5549.46230347.131900.662405.694304.84820HepG2RPS19
ZC3H4ENSG00000130749.5433.45390276.941500.646203.487802.58800HepG2RPS3A
ZC3H4ENSG00000130749.5418.77270326.848900.357402.324401.72560HepG2SAFB2
ZC3H4ENSG00000130749.5403.29960260.786600.628903.394801.95340HepG2SART3
ZC3H4ENSG00000130749.51078.24600820.493700.394003.046602.30700HepG2SF3B1
ZC3H4ENSG00000130749.5805.39420538.111700.581707.084206.20770HepG2SF3B4
ZC3H4ENSG00000130749.5577.87490381.146300.600307.137406.18010HepG2SMN1
ZC3H4ENSG00000130749.5922.74350543.888300.7625013.6928012.44570HepG2SRSF5
ZC3H4ENSG00000130749.5389.03530240.934100.691204.126902.76100HepG2STIP1
ZC3H4ENSG00000130749.51015.90890618.526800.7158014.2817013.04780HepG2SUCLG1
ZC3H4ENSG00000130749.5381.32080504.85430-0.404902.790202.22760HepG2TAF15
ZC3H4ENSG00000130749.5361.19790463.89110-0.361002.171901.42920HepG2TIA1
ZC3H4ENSG00000130749.5565.25310359.831300.651507.689806.82740HepG2TRIM56
ZC3H4ENSG00000130749.5808.32310538.171700.586806.123404.75370HepG2TUFM
ZC3H4ENSG00000130749.51715.00220795.818901.1076019.9147018.17920HepG2U2AF1
ZC3H4ENSG00000130749.51402.24450799.667800.810202.196101.32920HepG2U2AF2
ZC3H4ENSG00000130749.5904.682801071.54870-0.244202.531902.00230HepG2ZNF622
ZC3H4ENSG00000130749.5369.72830749.17980-1.0188011.7135010.63990K562AGGF1
ZC3H4ENSG00000130749.5271.18890397.27730-0.550804.525002.55790K562AKAP1
ZC3H4ENSG00000130749.5606.05740823.13530-0.441703.217602.13810K562AKAP8
ZC3H4ENSG00000130749.5485.78080779.53090-0.682307.029205.94860K562AKAP8L
ZC3H4ENSG00000130749.51810.525001110.895900.704608.836906.52970K562APOBEC3C
ZC3H4ENSG00000130749.5605.50630817.86910-0.433702.400601.55470K562ATP5C1
ZC3H4ENSG00000130749.5381.53250657.42300-0.785007.159505.73370K562BOP1
ZC3H4ENSG00000130749.5674.14640412.802900.707506.691404.87470K562CCAR1
ZC3H4ENSG00000130749.5605.71570819.25020-0.435703.936702.12030K562CEBPZ
ZC3H4ENSG00000130749.5447.35470698.99000-0.643906.808305.56980K562CPSF6
ZC3H4ENSG00000130749.51157.753601547.47420-0.418602.403601.49610K562CELF1
ZC3H4ENSG00000130749.5283.08740402.49560-0.507703.389302.22090K562DDX3X
ZC3H4ENSG00000130749.5669.48000462.136500.534603.920402.29190K562DHX30
ZC3H4ENSG00000130749.5599.29580838.98550-0.485402.274501.49130K562DKC1
ZC3H4ENSG00000130749.5897.45250553.271900.697706.931405.43330K562EFTUD2
ZC3H4ENSG00000130749.5705.28520419.890300.748104.351103.06450K562EIF3A
ZC3H4ENSG00000130749.5789.81360420.483100.909404.749103.67370K562EIF4A3
ZC3H4ENSG00000130749.51565.117401258.900100.314003.329602.30190K562EIF4G2
ZC3H4ENSG00000130749.5299.69480454.41570-0.600503.697402.36750K562FKBP4
ZC3H4ENSG00000130749.5506.02010711.28190-0.491203.607902.62600K562FMR1
ZC3H4ENSG00000130749.5248.55590369.46920-0.571903.782202.17980K562FUS
ZC3H4ENSG00000130749.5950.79910437.280301.1205023.4537021.81220K562FXR1
ZC3H4ENSG00000130749.5285.41290401.61500-0.492803.006401.50470K562G3BP1
ZC3H4ENSG00000130749.5971.237601301.17600-0.421905.129003.60390K562GLRX3
ZC3H4ENSG00000130749.51117.672101359.65240-0.282701.961001.31890K562GRSF1
ZC3H4ENSG00000130749.5576.75190795.50030-0.463902.852301.76300K562HNRNPA1
ZC3H4ENSG00000130749.5853.14470523.725400.703908.066507.09660K562HNRNPC
ZC3H4ENSG00000130749.51756.018301186.683100.565302.492001.49510K562HNRNPL
ZC3H4ENSG00000130749.5775.946201423.58640-0.8755011.368009.78230K562HSPD1
ZC3H4ENSG00000130749.5461.74240827.36340-0.841404.795803.65480K562KIF1C
ZC3H4ENSG00000130749.5370.56840569.90080-0.621003.567102.49210K562KRR1
ZC3H4ENSG00000130749.5698.12000441.476900.661007.039705.67440K562MAGOH
ZC3H4ENSG00000130749.5562.19810791.92040-0.494304.168702.76680K562MAK16
ZC3H4ENSG00000130749.5699.38200440.570200.666607.189405.61040K562MATR3
ZC3H4ENSG00000130749.5990.506101368.01290-0.465807.194605.94230K562MTPAP
ZC3H4ENSG00000130749.5387.03190649.64290-0.747203.558202.52930K562NAA15
ZC3H4ENSG00000130749.5977.234101520.00710-0.6373016.8830015.25020K562NSUN2
ZC3H4ENSG00000130749.5248.03800799.59600-1.688702.438601.52320K562PABPN1
ZC3H4ENSG00000130749.5558.93050392.791800.508803.605002.49160K562PCBP2
ZC3H4ENSG00000130749.5899.955701191.82670-0.405203.029502.16610K562PPIG
ZC3H4ENSG00000130749.51005.61950538.400200.9012010.871009.37030K562PRPF8
ZC3H4ENSG00000130749.5783.61830428.927900.8693012.3869011.03310K562PTBP1
ZC3H4ENSG00000130749.52243.142901373.612500.707406.516505.26500K562PUF60
ZC3H4ENSG00000130749.5276.98320773.25690-1.4811013.4521012.30040K562PUS1
ZC3H4ENSG00000130749.5744.34270440.365400.757204.393701.94160K562RBFOX2
ZC3H4ENSG00000130749.5443.39700753.27640-0.764605.986505.14050K562RBM15
ZC3H4ENSG00000130749.5602.38470411.250800.550604.412103.31970K562RBM22
ZC3H4ENSG00000130749.598.44870165.45250-0.749003.065901.65880K562RBM25
ZC3H4ENSG00000130749.5714.98900400.921600.834508.707005.99680K562RBM34
ZC3H4ENSG00000130749.5736.80180432.785000.767507.905505.98960K562NELFE
ZC3H4ENSG00000130749.5513.85210271.709700.919207.154805.44770K562RPS3
ZC3H4ENSG00000130749.51069.12770662.594900.690105.175003.69480K562SAFB
ZC3H4ENSG00000130749.5934.295701499.82660-0.682805.756104.61230K562SF3A3
ZC3H4ENSG00000130749.5260.24620181.381100.520802.790501.93130K562SF3B4
ZC3H4ENSG00000130749.5575.31510420.500500.452103.134002.38530K562SRSF1
ZC3H4ENSG00000130749.5497.92330262.244800.924908.589706.60160K562SRSF4
ZC3H4ENSG00000130749.5601.28120840.31410-0.482905.473903.81210K562SRSF7
ZC3H4ENSG00000130749.5947.700901260.11830-0.411103.104601.76710K562STAU1
ZC3H4ENSG00000130749.51088.60220745.797000.545506.456605.19430K562SYNCRIP
ZC3H4ENSG00000130749.5741.92460425.556300.801808.582607.24830K562TARDBP
ZC3H4ENSG00000130749.5715.09780410.501800.800709.932308.26720K562TIA1
ZC3H4ENSG00000130749.51167.668801611.69400-0.464908.376407.21000K562UPF1
ZC3H4ENSG00000130749.5836.228501379.07850-0.7217010.976709.17850K562WDR3
ZC3H4ENSG00000130749.51209.982201434.06220-0.245102.831801.97620K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ZC3H4 is not available on ENCORE database.





8 RBPs can affect the splicing of ZC3H4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEZC3H4ENSG00000130749.5chr19-4761415147614213475976454759786547615404476155040.298000.000900.01917includedK562SRSF1
SEZC3H4ENSG00000130749.5chr19-475723484757260047567443475711264757503447575378-0.492000.000450.01083excludedK562SRSF1
SEZC3H4ENSG00000130749.5chr19-4761415147614213475976454759786547615404476155040.455000.000000.00761includedHepG2LARP7
SEZC3H4ENSG00000130749.5chr19-475723484757260047567443475711264757503447575378-0.442000.000000.00002excludedK562AQR
SEZC3H4ENSG00000130749.5chr19-4761415147614213475976454759786547615404476155040.380000.000010.01071includedHepG2LIN28B
SEZC3H4ENSG00000130749.5chr19-475723484757260047567443475711264757503447575378-0.705000.000000.00000excludedHepG2SRSF1
SEZC3H4ENSG00000130749.5chr19-4761415147614213475976454759786547615404476155040.388000.000030.06007includedHepG2NIP7
SEZC3H4ENSG00000130749.5chr19-4761415147614213475976454759786547615404476155040.244000.000660.02912includedK562PTBP1
SEZC3H4ENSG00000130749.5chr19-475723484757260047567443475711264757503447575378-0.410000.007090.09075excludedK562HNRNPC
A3SSZC3H4ENSG00000130749.5chr19-4759327547593503475932754759344647597226475974120.063000.012800.06529longerK562AQR
MXEZC3H4ENSG00000130749.5chr19-47589640475897954759322347593446475885744758867147597226475973370.196000.000370.009291includedK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ZC3H4 is not avaliable on ENCORE database.