UBE2O

General Information

Gene Name       : UBE2O
Gene ID             : ENSG00000175931.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: UBE2O)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBE2OENSG00000175931.126.3512.309.32ENCSR000AEF
HepG2UBE2OENSG00000175931.1239.1618.1128.63ENCSR985KAT
K562UBE2OENSG00000175931.1218.3816.4717.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UBE2O is not avaliable on ENCORE database.



Proteins bound to RNA
  • UBE2O RNA is bound by 36 proteins.  







eCLIP assay for UBE2O is not avaliable on ENCORE database.





36 proteins are bound to UBE2O RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177438580074385898-3'-UTR,intron-Distal,intron-Proximal3.535966.94069K562PABPC4
chr177438648474386585-3'-UTR,intron-Distal3.764078.82905K562UPF1
chr177438616474386204-3'-UTR,intron-Distal3.413853.37083K562UPF1
chr177438623274386293-3'-UTR,intron-Distal3.648524.81659HepG2UPF1
chr177438663874386753-3'-UTR,intron-Distal4.8819415.35482HepG2UPF1
chr177438562574385721-3'-UTR,intron-Distal5.2285312.07925K562PUM2
chr177438651874386598-3'-UTR,intron-Distal3.710075.56003HepG2AKAP1
chr177438650874386589-3'-UTR,intron-Distal5.3670410.35090HepG2UPF1
chr177438656574386599-3'-UTR,intron-Distal3.117995.34378K562YBX3
chr177438651174386578-3'-UTR,intron-Distal3.512213.55142K562METAP2
chr177438589574385970-3'-UTR,intron-Distal6.3918626.59053K562PUM2
chr177438578974385848-3'-UTR,intron-Distal,intron-Proximal3.305583.50315HepG2UPF1
chr177438578174385879-3'-UTR,intron-Distal,intron-Proximal3.182543.44854HepG2LARP4
chr177438581174385873-3'-UTR,intron-Distal,intron-Proximal3.274556.69575HepG2DDX55
chr177438651974386572-3'-UTR,intron-Distal3.661274.59929HepG2RBM15
chr177438687474386957-3'-UTR,intron-Distal3.331706.41369HepG2PCBP2
chr177438588774385971-3'-UTR,intron-Distal3.146694.07923K562UPF1
chr177438614974386213-3'-UTR,intron-Distal4.387683.95192HepG2UPF1
chr177438626974386324-3'-UTR,intron-Distal3.325455.32141K562UPF1
chr177438602774386073-3'-UTR,intron-Distal4.463624.56348K562UPF1
chr177438665474386723-3'-UTR,intron-Distal4.087513.98590HepG2AKAP1
chr177439452674394575-CDS,intron-Distal,intron-Proximal3.181135.90285HepG2PRPF8
chr177439176274391811-CDS,intron-Distal,intron-Proximal3.964655.05356HepG2PRPF8
chr177438768574387777-CDS,intron-Distal,intron-Proximal3.413703.81705HepG2SF3B4
chr177439550074395536-CDS,intron-Distal,intron-Proximal3.911089.78274K562AQR
chr177439235974392418-CDS,intron-Distal4.724605.60278HepG2FXR2
chr177439562874395660-CDS,intron-Distal4.097814.04622HepG2GRWD1
chr177440159574401634-CDS,intron-Distal3.352103.69481K562UCHL5
chr177439506374395128-CDS,intron-Distal,intron-Proximal5.124754.97857HepG2AQR
chr177439552874395561-CDS,intron-Distal,intron-Proximal3.611695.30777HepG2PPIG
chr177439387974393946-CDS,intron-Distal,intron-Proximal3.134686.17838K562ZNF622
chr177439559974395654-CDS,intron-Distal3.321423.47314HepG2G3BP1
chr177439870374398743-CDS,intron-Distal,intron-Proximal3.014005.54641HepG2PPIG
chr177439389574393939-CDS,intron-Distal3.487204.41784HepG2GRWD1
chr177439720274397256-CDS,intron-Distal,intron-Proximal3.960407.37475HepG2U2AF2
chr177439712174397168-CDS,intron-Distal3.033765.44739HepG2GRWD1
chr177439223774392283-CDS,intron-Distal4.105413.73331K562RBM15
chr177439227274392501-CDS,intron-Distal3.356687.67473K562ZNF800
chr177439232774392427-CDS,intron-Distal3.583538.95550HepG2GRWD1
chr177439876574398781-CDS,intron-Distal,intron-Proximal3.935465.24452HepG2PPIG
chr177439256574392643-CDS,intron-Distal3.271154.04703HepG2FXR2
chr177439241974392660-CDS,intron-Distal3.9709811.83934HepG2G3BP1
chr177439807574398148-CDS,intron-Distal,intron-Proximal3.274915.11245K562AQR
chr177439388574393932-CDS,intron-Distal,intron-Proximal3.236253.50786HepG2G3BP1
chr177439709474397152-CDS,intron-Distal3.286937.63733HepG2PPIG
chr177439247474392537-CDS,intron-Distal4.937926.66343K562FMR1
chr177438747674387568-CDS,intron-Distal4.267633.98353K562RBM15
chr177439277474392834-CDS,intron-Distal3.390173.97184HepG2G3BP1
chr177439228474392458-CDS,intron-Distal3.049009.46124HepG2PPIG
chr177444918374449218-CDS,intron-Distal5.491933.73688K562GEMIN5
chr177439227574392332-CDS,intron-Distal3.813524.49347K562UCHL5
chr177439552474395600-CDS,intron-Distal,intron-Proximal3.567924.59873K562UCHL5
chr177438742474387550-CDS,intron-Distal4.349318.14334HepG2RBM15
chr177439265874392774-CDS,intron-Distal4.8875314.07362K562UCHL5
chr177439494874394966-CDS,intron-Distal3.877083.79347HepG2GRWD1
chr177438707474387151-CDS,intron-Distal4.240404.46921K562RBM15
chr177439653274396593-CDS,intron-Distal3.411895.76403K562UCHL5
chr177439268474392731-CDS,intron-Distal4.091703.96931HepG2G3BP1
chr177439662174396689-CDS,intron-Distal,intron-Proximal5.367674.90235K562SF3B4
chr177439234974392437-CDS,intron-Distal4.6679911.10249K562UCHL5
chr177439654374396590-CDS,intron-Distal3.986976.91167HepG2GRWD1
chr177440151674401599-CDS,intron-Distal,intron-Proximal3.269267.39618HepG2PRPF8
chr177439599674396071-CDS,intron-Distal,intron-Proximal4.730498.63544HepG2SF3A3
chr177439595174396019-CDS,intron-Distal,intron-Proximal3.239885.12722K562BUD13
chr177439222174392264-CDS,intron-Distal3.927923.11149HepG2G3BP1
chr177440157874401650-CDS,intron-Distal,intron-Proximal3.525335.71175HepG2BUD13
chr177439631274396365-CDS,intron-Distal3.725985.99043HepG2GRWD1
chr177439437674394434-CDS,intron-Distal3.041734.50748HepG2GRWD1
chr177439388274393935-CDS,intron-Distal,intron-Proximal3.497667.64107HepG2PPIG
chr177440159674401650-CDS,intron-Distal4.0755110.42618HepG2PPIG
chr177439247774392539-CDS,intron-Distal3.445905.62598K562FXR2
chr177439615674396230-CDS,intron-Distal,intron-Proximal5.308245.69951K562AQR
chr177439231574392407-CDS,intron-Distal3.2467510.60417HepG2BUD13
chr177439581174395874-CDS,intron-Distal,intron-Proximal4.796736.78401HepG2GRWD1
chr177438750174387520-CDS,intron-Distal3.898113.60441HepG2GRWD1
chr177440124874401306-CDS,intron-Distal,intron-Proximal3.303687.02084HepG2PRPF8
chr177441221774412278-intron-Distal4.063099.60323HepG2HNRNPL
chr177439663774396713-intron-Distal,intron-Proximal4.429715.54524HepG2SF3B4
chr177443184074432024-intron-Distal4.058413.07980HepG2HNRNPM
chr177442429474424401-intron-Distal4.449996.25977K562SAFB2
chr177439613374396196-intron-Distal,intron-Proximal3.956125.84589K562EFTUD2
chr177442590374426123-intron-Distal4.4045511.92176K562SAFB2
chr177441227874412303-intron-Distal3.261485.31122HepG2HNRNPL
chr177444747574447548-intron-Distal3.202994.54315HepG2HNRNPL
chr177444747974447552-intron-Distal3.904004.02823K562HNRNPL
chr177441222874412281-intron-Distal5.668969.70777K562AGGF1
chr177444359274443652-intron-Distal4.215654.13641K562TARDBP
chr177444421874444287-intron-Distal3.058923.63132HepG2HNRNPC
chr177439729774397382-intron-Distal,intron-Proximal3.555283.04890HepG2UCHL5
chr177442374974423819-intron-Distal4.997286.81402HepG2HLTF
chr177439209674392157-intron-Distal,intron-Proximal3.813246.15459HepG2GRWD1
chr177444704974447106-intron-Distal3.325853.50045HepG2SFPQ
chr177442823374428314-intron-Distal3.778225.89423HepG2HNRNPM
chr177441230374412348-intron-Distal4.4541510.74543HepG2HNRNPL
chr177439546774395500-intron-Distal,intron-Proximal6.0215612.64691K562AQR
chr177439487474394918-intron-Distal,intron-Proximal5.269436.69228HepG2PRPF8
chr177441218374412342-intron-Distal5.9676816.30531K562HNRNPL
chr177440140274401470-intron-Distal,intron-Proximal4.443474.28193HepG2AQR
chr177442587074426029-intron-Distal4.1327010.59173HepG2HLTF
chr177440314174403346-intron-Distal4.009453.30664K562NONO
chr177444871574448772-intron-Distal3.679973.06347K562NONO
chr177442420774424232-intron-Distal4.039733.55983HepG2HLTF
chr177444228274442358-intron-Distal3.238363.39857HepG2HNRNPM
chr177442315674423245-intron-Distal4.147804.37667K562SAFB2
chr177444714274447212-intron-Distal3.097414.53269HepG2HNRNPM
chr177439857374398630-intron-Distal,intron-Proximal4.432636.67793HepG2EFTUD2
chr177439704774397073-intron-Distal,intron-Proximal4.942345.65342K562AQR
chr177439611474396167-intron-Distal,intron-Proximal4.889204.90235K562SF3B4
chr177439616174396208-intron-Distal,intron-Proximal5.545838.95390HepG2RBM22
chr177439507374395137-intron-Distal,intron-Proximal3.632763.81705HepG2SF3B4
chr177442871774428779-intron-Distal3.566387.15089HepG2HNRNPM
chr177442432174424377-intron-Distal4.475094.15056HepG2HLTF
chr177440141574401477-intron-Distal,intron-Proximal3.507495.00060HepG2SF3B4
chr177442602974426098-intron-Distal3.184015.33504HepG2HLTF
chr177441223274412288-intron-Distal3.915824.11570HepG2AGGF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UBE2O is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UBE2O is not available on ENCORE database.

  • 87 RBPs can affect the levels of UBE2O.  








The Knockdown/knockout RNA-Seq assay for UBE2O is not available on ENCORE database.





87 RBPs can affect the gene expression of UBE2O :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UBE2OENSG00000175931.8859.062401316.40550-0.615806.055804.53370HepG2AATF
UBE2OENSG00000175931.81384.364102232.36920-0.689404.104702.97270HepG2ABCF1
UBE2OENSG00000175931.81242.368301723.60600-0.472302.348401.62220HepG2ASCC1
UBE2OENSG00000175931.81020.983401375.97150-0.430502.659001.90220HepG2CALR
UBE2OENSG00000175931.81657.164202108.38160-0.347406.478105.53800HepG2CKAP4
UBE2OENSG00000175931.81523.712901220.597300.319903.496502.35030HepG2YBX3
UBE2OENSG00000175931.82446.253602030.323200.268803.463702.76180HepG2CELF1
UBE2OENSG00000175931.81717.421301950.40310-0.183502.039301.31420HepG2DDX19B
UBE2OENSG00000175931.81157.867401450.98510-0.325602.509301.86030HepG2DDX21
UBE2OENSG00000175931.81082.745901421.06900-0.392303.147002.17100HepG2DDX24
UBE2OENSG00000175931.8819.530201341.66630-0.711204.121202.93990HepG2DDX59
UBE2OENSG00000175931.82577.063901714.715700.587705.461104.61880HepG2DDX6
UBE2OENSG00000175931.81322.546302017.63080-0.6093013.7866012.51210HepG2DKC1
UBE2OENSG00000175931.81025.461501589.65790-0.632407.030905.63220HepG2EEF2
UBE2OENSG00000175931.8956.538901325.01580-0.470104.163102.79940HepG2EFTUD2
UBE2OENSG00000175931.82383.666901647.723300.532605.235604.43500HepG2EIF2S1
UBE2OENSG00000175931.8788.535201290.32610-0.710508.074006.60460HepG2EIF3D
UBE2OENSG00000175931.81016.060801371.00050-0.432203.892002.63780HepG2EIF3G
UBE2OENSG00000175931.82507.838001773.234000.500003.354302.60060HepG2EIF4B
UBE2OENSG00000175931.81770.264002153.73520-0.282903.327902.42500HepG2EIF4G1
UBE2OENSG00000175931.82155.582402843.50180-0.399607.914906.98770HepG2ETF1
UBE2OENSG00000175931.81694.290602060.71880-0.282502.485301.69280HepG2EWSR1
UBE2OENSG00000175931.81719.913702253.96700-0.390102.144501.46310HepG2FIP1L1
UBE2OENSG00000175931.81150.685901704.40060-0.566803.581602.82890HepG2G3BP1
UBE2OENSG00000175931.8821.537201148.83260-0.483803.923502.84260HepG2GEMIN5
UBE2OENSG00000175931.81051.144801339.14770-0.349401.912901.37460HepG2GPKOW
UBE2OENSG00000175931.8897.485401397.09900-0.638503.230001.72260HepG2HLTF
UBE2OENSG00000175931.81624.574602006.24770-0.304403.820102.74770HepG2HNRNPA2B1
UBE2OENSG00000175931.81222.174801554.61340-0.347102.245801.38790HepG2HNRNPM
UBE2OENSG00000175931.81645.413201365.666100.268703.402602.59560HepG2ILF2
UBE2OENSG00000175931.81541.839801927.76190-0.322305.515304.09100HepG2KIF1C
UBE2OENSG00000175931.81935.627502589.48050-0.419902.825201.98750HepG2LARP4
UBE2OENSG00000175931.8833.406701350.35650-0.696204.187002.90600HepG2METAP2
UBE2OENSG00000175931.81169.055001823.37630-0.641305.561104.44900HepG2MSI2
UBE2OENSG00000175931.82280.925101322.509700.786204.615503.44890HepG2PABPC1
UBE2OENSG00000175931.81064.578301323.32660-0.313903.517002.57300HepG2PARN
UBE2OENSG00000175931.82256.581201768.525600.351505.738804.91540HepG2PCBP1
UBE2OENSG00000175931.8849.221801067.08960-0.329502.937101.66680HepG2PKM
UBE2OENSG00000175931.8609.255301033.39000-0.762308.570307.23380HepG2PRPF8
UBE2OENSG00000175931.81649.109902066.33320-0.325402.830202.22770HepG2PUF60
UBE2OENSG00000175931.82630.459702191.924200.263002.628701.97400HepG2PUM2
UBE2OENSG00000175931.81566.631302148.04330-0.455409.646108.61300HepG2PUS1
UBE2OENSG00000175931.81033.058901598.71280-0.630008.309207.22450HepG2RPLP0
UBE2OENSG00000175931.8749.925001255.66810-0.7436011.031409.90270HepG2RPS19
UBE2OENSG00000175931.81143.264201416.55480-0.309202.336201.59680HepG2RPS2
UBE2OENSG00000175931.81649.890401190.610600.470609.171408.10660HepG2SAFB2
UBE2OENSG00000175931.8825.270801260.06250-0.610606.653605.20760HepG2SERBP1
UBE2OENSG00000175931.82299.376701981.413400.214603.168802.42590HepG2SLBP
UBE2OENSG00000175931.81076.298601955.58130-0.8615025.6858024.56410HepG2SRSF1
UBE2OENSG00000175931.81848.331701591.015800.216202.534902.00120HepG2SRSF9
UBE2OENSG00000175931.81896.172102330.47670-0.297504.570803.94500HepG2SSB
UBE2OENSG00000175931.81612.992502320.29300-0.5246012.7431011.57190HepG2SUCLG1
UBE2OENSG00000175931.8706.095201333.93780-0.9178011.8186010.58180HepG2SUPV3L1
UBE2OENSG00000175931.81323.388501757.90190-0.409605.292704.55860HepG2TAF15
UBE2OENSG00000175931.8848.351601298.97840-0.614608.890708.08620HepG2TIAL1
UBE2OENSG00000175931.81625.061201310.740100.310002.187001.67380HepG2TRIM56
UBE2OENSG00000175931.8724.093401025.23700-0.501703.454701.70240HepG2TROVE2
UBE2OENSG00000175931.81863.076502167.63500-0.218401.902901.30550HepG2UPF1
UBE2OENSG00000175931.8705.127001393.62090-0.9829030.5512028.77930HepG2ZC3H8
UBE2OENSG00000175931.82822.903202383.972100.243703.082502.51430HepG2ZNF622
UBE2OENSG00000175931.82421.978901737.143600.4794010.367009.35910K562AGGF1
UBE2OENSG00000175931.82422.034901807.601200.422004.797203.92980K562AKAP8L
UBE2OENSG00000175931.82775.728802081.238900.415304.379103.67280K562AQR
UBE2OENSG00000175931.81452.617301188.068600.289902.847801.51190K562BCCIP
UBE2OENSG00000175931.81505.344101104.576000.446503.663602.60120K562EFTUD2
UBE2OENSG00000175931.8785.55290618.118900.345702.714801.92520K562EIF3G
UBE2OENSG00000175931.81655.675701261.292900.392403.765002.81200K562EIF4A3
UBE2OENSG00000175931.81623.784201311.697200.307803.591602.91610K562FXR1
UBE2OENSG00000175931.8204.72610568.46860-1.473405.729304.62860K562G3BP2
UBE2OENSG00000175931.81101.10330877.925600.326702.379901.64130K562GPKOW
UBE2OENSG00000175931.81162.019801573.79010-0.437603.912102.96940K562HSPD1
UBE2OENSG00000175931.81435.26800927.057900.630504.697703.21440K562IGF2BP2
UBE2OENSG00000175931.81236.34340942.718100.391103.391402.03650K562IGF2BP3
UBE2OENSG00000175931.82328.290401918.230500.279402.719201.90190K562KIF1C
UBE2OENSG00000175931.81326.34270973.744100.445704.616503.52490K562MAGOH
UBE2OENSG00000175931.81310.95590971.684000.432004.418903.22700K562MATR3
UBE2OENSG00000175931.82189.526301859.421800.235703.823902.96250K562NSUN2
UBE2OENSG00000175931.81663.475001087.080700.613602.631501.67160K562PABPN1
UBE2OENSG00000175931.81147.45960946.095100.278302.117901.52370K562PTBP1
UBE2OENSG00000175931.83285.862302714.131300.275702.511801.73470K562PUF60
UBE2OENSG00000175931.82460.802601746.636300.494403.246002.61200K562RBM15
UBE2OENSG00000175931.81116.99210906.887800.300502.055801.33590K562RBM22
UBE2OENSG00000175931.81208.67240954.425500.340602.386901.38710K562NELFE
UBE2OENSG00000175931.81685.05580994.131400.761203.078701.78830K562SF1
UBE2OENSG00000175931.82350.607701834.854200.357305.138304.05360K562SF3A3
UBE2OENSG00000175931.8911.66240590.400000.626702.957102.07200K562SF3B4
UBE2OENSG00000175931.81900.605101211.910700.649102.577101.33840K562SFPQ
UBE2OENSG00000175931.8419.81290567.59180-0.435102.947201.31460K562SND1
UBE2OENSG00000175931.81222.05500876.157000.479904.471003.08160K562SRSF5
UBE2OENSG00000175931.81527.69550938.607500.702706.876205.71320K562TARDBP
UBE2OENSG00000175931.81252.21630905.428300.467705.075403.91590K562TIA1
UBE2OENSG00000175931.81278.69020888.813600.524605.310303.69180K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UBE2O is not available on ENCORE database.





6 RBPs can affect the splicing of UBE2O :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUBE2OENSG00000175931.8chr17-743878367438789474385877743876947438799074388194-0.153000.000460.01073excludedHepG2U2AF1
A3SSUBE2OENSG00000175931.8chr17-7439387974393972743938797439396974394335743944640.123000.000550.06422longerK562FXR1
A3SSUBE2OENSG00000175931.8chr17-7439455274394724743945527439466574394917743950720.151000.000000.00000longerK562AQR
A3SSUBE2OENSG00000175931.8chr17-7439802774398273743980277439820874398682743987220.139000.000010.00011longerK562AQR
A3SSUBE2OENSG00000175931.8chr17-7439652174396737743965217439663174397091743972350.086000.000110.00096longerK562AQR
A5SSUBE2OENSG00000175931.8chr17-743878367438806374387990743880637438553174387694-0.242000.000800.06409shorterHepG2U2AF1
RIUBE2OENSG00000175931.8chr17-7438783674388063743878367438789474387990743880630.062000.000100.00130includedHepG2SF3B4
RIUBE2OENSG00000175931.8chr17-7438783674388063743878367438789474387990743880630.055000.000390.00885includedHepG2SRSF9
RIUBE2OENSG00000175931.8chr17-7438783674388063743878367438789474387990743880630.058000.009710.07830includedK562EFTUD2
RIUBE2OENSG00000175931.8chr17-7438783674388063743878367438789474387990743880630.085000.000030.00026includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UBE2O is not avaliable on ENCORE database.