TRMT6

General Information

Gene Name       : TRMT6
Gene ID             : ENSG00000089195.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TRMT6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TRMT6ENSG00000089195.1424.3624.1724.27ENCSR000AEF
HepG2TRMT6ENSG00000089195.1421.2133.7527.48ENCSR985KAT
K562TRMT6ENSG00000089195.1414.0014.3314.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TRMT6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TRMT6 RNA is bound by 3 proteins.  







eCLIP assay for TRMT6 is not avaliable on ENCORE database.





3 proteins are bound to TRMT6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2059245985924662-3'-UTR,CDS,intron-Distal4.256603.06595HepG2BCLAF1
chr2059309625931069-5'-UTR,CDS,intron-Distal,intron-Proximal4.030313.12746HepG2GRWD1
chr2059270525927158-5'-UTR,CDS,intron-Distal4.521634.23295HepG2GRWD1
chr2059309975931158-5'-UTR,CDS,intron-Distal,intron-Proximal3.487144.09778HepG2NCBP2
chr2059225925922664-CDS,intron-Distal,intron-Proximal3.484023.28366HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TRMT6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TRMT6 is not available on ENCORE database.

  • 101 RBPs can affect the levels of TRMT6.  








The Knockdown/knockout RNA-Seq assay for TRMT6 is not available on ENCORE database.





101 RBPs can affect the gene expression of TRMT6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TRMT6ENSG00000089195.10790.31080465.428900.7638012.9584011.84590HepG2ACO1
TRMT6ENSG00000089195.101641.69340562.095201.5462026.7859025.32980HepG2AKAP1
TRMT6ENSG00000089195.10651.03930465.093900.485103.098902.26770HepG2ASCC1
TRMT6ENSG00000089195.10405.96870579.97210-0.514602.577301.70820HepG2BCLAF1
TRMT6ENSG00000089195.101722.366801342.386900.359503.123902.49210HepG2BOP1
TRMT6ENSG00000089195.10948.52570736.830300.364302.962702.16690HepG2CALR
TRMT6ENSG00000089195.10745.09400465.325500.6791010.521709.39580HepG2CKAP4
TRMT6ENSG00000089195.10594.49030393.008300.597002.679201.92720HepG2CNOT7
TRMT6ENSG00000089195.10720.674101232.39940-0.774109.332208.14230HepG2CPSF6
TRMT6ENSG00000089195.10616.76780430.454000.518806.112704.94180HepG2DDX19B
TRMT6ENSG00000089195.10964.18320538.460400.840408.883407.81660HepG2DDX3X
TRMT6ENSG00000089195.10330.32160462.51160-0.485602.410101.82980HepG2DDX6
TRMT6ENSG00000089195.10295.14940504.19070-0.772508.361007.19080HepG2DNAJC21
TRMT6ENSG00000089195.10349.52480499.73310-0.515805.152404.30680HepG2DNAJC2
TRMT6ENSG00000089195.10704.26960489.609400.524403.591702.55040HepG2EEF2
TRMT6ENSG00000089195.10623.12290408.167700.610304.722903.27260HepG2EFTUD2
TRMT6ENSG00000089195.10324.21100444.66040-0.455802.242901.70350HepG2EIF2S1
TRMT6ENSG00000089195.10718.82330554.774100.373602.848401.66010HepG2EIF2S2
TRMT6ENSG00000089195.10639.52350397.456700.686105.724604.45800HepG2EIF3D
TRMT6ENSG00000089195.10820.15830478.432200.777505.576204.62210HepG2EIF4B
TRMT6ENSG00000089195.10445.24700733.50060-0.720207.188105.90220HepG2EIF4G2
TRMT6ENSG00000089195.10704.00500454.805200.630204.094003.07900HepG2EWSR1
TRMT6ENSG00000089195.10545.60360355.221600.619005.733804.00860HepG2FAM120A
TRMT6ENSG00000089195.10844.94180576.228600.552103.213002.00780HepG2FUS
TRMT6ENSG00000089195.10731.45180495.768100.561004.063303.23610HepG2FXR1
TRMT6ENSG00000089195.10900.270801397.06190-0.634005.882404.97220HepG2GPKOW
TRMT6ENSG00000089195.10627.959101078.03000-0.7797014.4508012.98540HepG2HNRNPF
TRMT6ENSG00000089195.10674.47110465.650600.534403.909803.09270HepG2HNRNPK
TRMT6ENSG00000089195.10595.03800707.06180-0.248902.076301.48130HepG2HNRNPL
TRMT6ENSG00000089195.10643.838601333.23810-1.0502015.8779014.54210HepG2HNRNPLL
TRMT6ENSG00000089195.10868.13190509.518600.7687010.464108.82880HepG2HNRNPM
TRMT6ENSG00000089195.10749.69350528.813100.503402.962801.68720HepG2HSPD1
TRMT6ENSG00000089195.10583.019901061.56190-0.8646013.5805012.10180HepG2IGF2BP1
TRMT6ENSG00000089195.101016.76070438.701901.212606.000504.57860HepG2IGF2BP3
TRMT6ENSG00000089195.10328.78390425.45900-0.371902.639701.64120HepG2KIF1C
TRMT6ENSG00000089195.10648.78630446.970300.537504.052002.67000HepG2LARP7
TRMT6ENSG00000089195.10717.33940495.941000.532403.678002.92260HepG2MAGOH
TRMT6ENSG00000089195.101261.65650498.725501.3389020.1200018.54720HepG2MATR3
TRMT6ENSG00000089195.10778.05490415.976500.903306.009804.50950HepG2METAP2
TRMT6ENSG00000089195.10970.53680597.758700.699109.096707.70660HepG2MSI2
TRMT6ENSG00000089195.101001.054001359.63960-0.441702.482101.56730HepG2MTPAP
TRMT6ENSG00000089195.10781.80640510.480300.614904.739703.92350HepG2NCBP2
TRMT6ENSG00000089195.10855.693601182.14070-0.466204.005903.11060HepG2NSUN2
TRMT6ENSG00000089195.10628.03910453.150200.470803.442701.64390HepG2NUP35
TRMT6ENSG00000089195.10480.66120297.132300.693803.545801.72980HepG2PA2G4
TRMT6ENSG00000089195.10708.53680556.728200.347802.925602.05700HepG2PARN
TRMT6ENSG00000089195.10617.97150448.776000.461404.240903.51750HepG2PCBP1
TRMT6ENSG00000089195.10449.26660328.686300.450803.011601.72630HepG2PKM
TRMT6ENSG00000089195.10391.85580501.65780-0.356402.396801.70640HepG2PPIL4
TRMT6ENSG00000089195.10929.14740573.465200.696102.578301.39720HepG2PRPF6
TRMT6ENSG00000089195.10574.32290456.632500.330702.198701.70010HepG2PTBP1
TRMT6ENSG00000089195.10580.12970734.68910-0.340802.317201.76510HepG2PUF60
TRMT6ENSG00000089195.101204.91890779.885100.6275013.0238011.93760HepG2PUM1
TRMT6ENSG00000089195.101495.95130526.455701.5066015.8901014.33950HepG2RAVER1
TRMT6ENSG00000089195.101036.82980732.923300.500305.222304.08840HepG2RBM15
TRMT6ENSG00000089195.101588.62700845.089200.9105021.5794020.40940HepG2RBM22
TRMT6ENSG00000089195.10731.88720538.978200.441302.705501.72290HepG2RBM27
TRMT6ENSG00000089195.10614.34680437.674500.489102.705101.65880HepG2RCC2
TRMT6ENSG00000089195.10731.25830508.199600.524905.379604.66540HepG2NELFE
TRMT6ENSG00000089195.10843.404301161.15190-0.461303.994503.19830HepG2RPLP0
TRMT6ENSG00000089195.10745.96060386.741500.9476012.5801011.38390HepG2RPS19
TRMT6ENSG00000089195.10742.93930507.412000.550004.112402.78850HepG2RPS5
TRMT6ENSG00000089195.10685.51570500.898900.452602.918602.11430HepG2RRP9
TRMT6ENSG00000089195.10405.81840500.88470-0.303602.035801.47000HepG2SAFB2
TRMT6ENSG00000089195.10586.75910388.157600.596004.544103.35370HepG2SERBP1
TRMT6ENSG00000089195.101207.66570766.240500.656305.090304.15690HepG2SF3A3
TRMT6ENSG00000089195.10500.52980704.41150-0.493005.824204.86850HepG2SLBP
TRMT6ENSG00000089195.10944.17280496.244400.9279017.4827016.50880HepG2SRSF1
TRMT6ENSG00000089195.10956.23010725.374700.398504.313103.56210HepG2SRSF5
TRMT6ENSG00000089195.10599.327501059.09410-0.8214015.6754014.25490HepG2SRSF7
TRMT6ENSG00000089195.10630.09730828.70830-0.395304.292503.68330HepG2SSB
TRMT6ENSG00000089195.10644.53330446.015800.531105.024104.30550HepG2TAF15
TRMT6ENSG00000089195.10912.455101299.38520-0.510004.881803.95710HepG2TARDBP
TRMT6ENSG00000089195.10298.55470551.40710-0.8851012.5732011.49710HepG2TRIM56
TRMT6ENSG00000089195.101541.25110631.653901.2868014.0636012.61110HepG2U2AF1
TRMT6ENSG00000089195.101619.63550656.067101.3037047.9030045.86540HepG2UTP3
TRMT6ENSG00000089195.10893.69160578.925200.626304.047902.76860HepG2XRCC6
TRMT6ENSG00000089195.10411.74720635.51690-0.626208.020906.97650HepG2ZC3H8
TRMT6ENSG00000089195.10997.70300747.361700.416705.876205.15720HepG2ZNF622
TRMT6ENSG00000089195.10430.75880280.366800.619504.324002.81090K562AARS
TRMT6ENSG00000089195.101000.47660593.765700.752603.821502.32960K562APOBEC3C
TRMT6ENSG00000089195.10898.92060572.560000.650704.552503.83410K562AQR
TRMT6ENSG00000089195.10411.69770599.85530-0.543002.510401.76160K562CPSF6
TRMT6ENSG00000089195.10977.38910630.422300.632509.802708.66610K562DDX47
TRMT6ENSG00000089195.10387.78090181.947101.091606.147204.60780K562EIF3A
TRMT6ENSG00000089195.10513.40670270.109800.926504.289903.30960K562EIF3G
TRMT6ENSG00000089195.10242.65700147.738600.715803.918102.94470K562EIF4A3
TRMT6ENSG00000089195.10431.27940660.92670-0.615904.107903.06100K562FIP1L1
TRMT6ENSG00000089195.10587.85320153.641401.9358039.8722037.71900K562FXR1
TRMT6ENSG00000089195.10205.65900371.37940-0.852603.242201.89120K562HNRNPA2B1
TRMT6ENSG00000089195.10355.93330220.799900.688804.090702.54800K562HNRNPK
TRMT6ENSG00000089195.10802.80030543.575900.562504.074202.93070K562HNRNPM
TRMT6ENSG00000089195.10379.68420232.304600.708704.389803.32630K562MAGOH
TRMT6ENSG00000089195.10356.57750231.852100.620904.376503.19210K562MATR3
TRMT6ENSG00000089195.101021.13900735.903100.472504.626002.66680K562NOL12
TRMT6ENSG00000089195.10138.63830325.02510-1.229205.523503.98970K562PABPN1
TRMT6ENSG00000089195.10523.21160750.21650-0.519902.565701.78090K562PPIG
TRMT6ENSG00000089195.10660.74720269.956101.2913016.5772014.72140K562PRPF8
TRMT6ENSG00000089195.10461.11850225.689201.0307012.1596010.81770K562PTBP1
TRMT6ENSG00000089195.101053.97140734.184100.521502.792701.97340K562PUF60
TRMT6ENSG00000089195.101100.57080780.673700.495406.383504.70770K562PUM1
TRMT6ENSG00000089195.10147.11330280.94150-0.933303.213102.63560K562PUS1
TRMT6ENSG00000089195.10328.05450216.476700.599603.677302.69660K562RBM22
TRMT6ENSG00000089195.10334.11500227.791300.552502.578801.52810K562NELFE
TRMT6ENSG00000089195.10481.47940275.017100.807905.827804.63680K562RPS19
TRMT6ENSG00000089195.10269.85150153.960500.809502.645401.66800K562RPS3
TRMT6ENSG00000089195.10523.11080309.844300.755506.811605.12410K562SAFB
TRMT6ENSG00000089195.10298.32800221.236700.431202.035401.41850K562SRSF1
TRMT6ENSG00000089195.10231.56240408.38520-0.818502.870701.41020K562SUPT6H
TRMT6ENSG00000089195.10724.58830348.780101.0547016.2802014.31570K562SYNCRIP
TRMT6ENSG00000089195.10324.48330223.936000.535002.875502.15570K562TARDBP
TRMT6ENSG00000089195.10152.55430281.07420-0.881605.569204.11520K562TRIM56
TRMT6ENSG00000089195.10457.50880773.40100-0.757404.965102.98940K562TRIP6
TRMT6ENSG00000089195.10331.35780176.991400.904607.658106.31490K562U2AF2
TRMT6ENSG00000089195.10325.54180521.29060-0.679203.872303.03440K562UPF1
TRMT6ENSG00000089195.10305.50840446.06120-0.546002.873201.97990K562WDR3
TRMT6ENSG00000089195.10556.42830264.657601.072006.414903.77600K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TRMT6 is not available on ENCORE database.





3 RBPs can affect the splicing of TRMT6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETRMT6ENSG00000089195.10chr20-592188859219915921698592178559225965922676-0.388000.000070.00197excludedHepG2U2AF1
SETRMT6ENSG00000089195.10chr20-592545059255605924807592489959270515927157-0.081000.004760.04465excludedK562AQR
A3SSTRMT6ENSG00000089195.10chr20-592188859219915921888592191959225965922682-0.341000.001940.04528shorterHepG2U2AF2
A3SSTRMT6ENSG00000089195.10chr20-5924472592471759244725924677592480759249370.128000.000130.00113longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-5925450592557859254505925560592705159272040.087000.000180.00151longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-5924807592496859248075924899592545059255780.115000.000150.00123longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-5922596592278659225965922682592307359234320.100000.000000.00001longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-5923320592351759233205923432592420459243620.132000.000010.00010longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-5927051592726759270515927179593092359311600.074000.001270.00862longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-5921888592202959218885921991592259659227860.155000.000750.00537longerK562AQR
A3SSTRMT6ENSG00000089195.10chr20-592188859219915921888592191959225965922682-0.478000.000000.00007shorterHepG2U2AF1
A5SSTRMT6ENSG00000089195.10chr20-5924472592467759245935924677592420459243290.091000.005570.07905longerK562AQR
MXETRMT6ENSG00000089195.10chr20-59248075924899592545059255605924593592467759270515927179-0.155000.017130.097212includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TRMT6 is not avaliable on ENCORE database.