TMEM57

General Information

Gene Name       : TMEM57
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM57)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM57 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM57 RNA is bound by 17 proteins.  







eCLIP assay for TMEM57 is not avaliable on ENCORE database.





17 proteins are bound to TMEM57 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12582618825826307+3'-UTR4.4836112.82485K562FAM120A
chr12582619625826314+3'-UTR5.206347.60978K562UPF1
chr12582618025826242+3'-UTR3.680893.61688HepG2FAM120A
chr12582499225825026+3'-UTR3.816063.15006K562RBM15
chr12575741025757604+5'-UTR,CDS3.2117112.85699K562DDX3X
chr12575743125757471+5'-UTR4.5640410.02475HepG2DDX3X
chr12575753625757590+5'-UTR3.274203.49263HepG2DDX3X
chr12575747125757536+5'-UTR5.7067416.00434HepG2DDX3X
chr12577528425775338+CDS,intron-Distal,intron-Proximal3.346425.18801K562U2AF1
chr12577528725775359+CDS,intron-Distal,intron-Proximal3.411099.46736K562U2AF2
chr12581221025812268+CDS3.7476212.28783K562UCHL5
chr12581222025812287+CDS,intron-Proximal5.651579.78817HepG2BCLAF1
chr12581803025818084+CDS,intron-Proximal3.433923.93112K562RBM15
chr12581226925812334+CDS,intron-Proximal3.407515.36110K562AQR
chr12581217725812288+CDS,intron-Proximal4.397727.44395K562TRA2A
chr12581572525815766+CDS3.193364.89070K562UCHL5
chr12581064025810725+CDS3.041356.29223K562UCHL5
chr12581222125812287+CDS,intron-Proximal3.433578.41511K562ZNF622
chr12581807325818086+CDS,intron-Proximal3.861684.64775K562SF3B4
chr12578324225783302+CDS,intron-Distal4.502194.46921K562RBM15
chr12578491825785022+CDS,intron-Distal3.235626.87198K562RBM15
chr12581566325815673+CDS,intron-Proximal3.913305.42720K562UCHL5
chr12578311825783171+CDS,intron-Distal,intron-Proximal3.121405.61685K562AQR
chr12581570825815770+CDS5.5848710.96424K562ZNF622
chr12581055625810634+CDS,intron-Proximal3.180393.73051K562SF3B4
chr12581792025818009+CDS3.503985.63425HepG2BCLAF1
chr12581226825812287+CDS,intron-Proximal4.4005312.69640K562UCHL5
chr12578512925785187+CDS,intron-Distal3.720393.87469HepG2BCLAF1
chr12578313025783224+CDS,intron-Distal,intron-Proximal3.584437.39702K562RBM15
chr12575780025757887+intron-Distal3.913335.26179K562XRN2
chr12577787025777900+intron-Distal4.637656.94732K562KHSRP
chr12577512225775160+intron-Distal3.871546.62503K562KHSRP
chr12578293925782986+intron-Distal4.536355.85529K562RBM15
chr12580570225805787+intron-Distal4.382984.93238K562QKI
chr12577790025777953+intron-Distal3.315375.57010K562KHSRP
chr12580569625805823+intron-Distal4.810664.85866HepG2QKI
chr12578539525785573+intron-Distal,intron-Proximal3.032128.07535K562PRPF8
chr12578547525785551+intron-Distal,intron-Proximal3.751809.94478K562KHSRP
chr12578282825782898+intron-Distal4.497225.40397K562LIN28B
chr12575955025759625+intron-Distal3.466225.40624K562KHSRP
chr12577563225775678+intron-Distal4.388404.71391K562U2AF2
chr12578021825780374+intron-Distal3.516898.87792K562KHSRP
chr12581039425810474+intron-Distal5.069206.02529K562SF3B4
chr12577516025775268+intron-Distal,intron-Proximal3.391219.07887K562KHSRP
chr12576169025761763+intron-Distal3.570194.56724K562KHSRP
chr12575962525759694+intron-Distal4.626425.91698K562KHSRP
chr12581578425815827+intron-Proximal5.060865.69951K562AQR
chr12581076525810809+intron-Proximal5.167366.44303K562AQR
chr12581808625818121+intron-Proximal3.959785.04653K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM57 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM57 is not available on ENCORE database.

  • 100 RBPs can affect the levels of TMEM57.  








The Knockdown/knockout RNA-Seq assay for TMEM57 is not available on ENCORE database.





100 RBPs can affect the gene expression of TMEM57 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM57ENSG00000204178.5722.392601302.68740-0.850608.794807.90740HepG2AKAP1
TMEM57ENSG00000204178.5562.26880725.75880-0.368203.358202.52310HepG2AKAP8L
TMEM57ENSG00000204178.5543.485801077.86470-0.9879012.7117011.13370HepG2ASCC1
TMEM57ENSG00000204178.51022.21220811.237400.333403.223002.49150HepG2AUH
TMEM57ENSG00000204178.51304.94860755.652900.7881010.844909.76220HepG2BOP1
TMEM57ENSG00000204178.51084.21310800.139000.438204.256203.32390HepG2CALR
TMEM57ENSG00000204178.5779.361601024.04560-0.393902.663701.90440HepG2CIRBP
TMEM57ENSG00000204178.5391.39890629.27210-0.685003.771602.87260HepG2CNOT7
TMEM57ENSG00000204178.51038.59370693.718900.582105.503104.56400HepG2CPSF6
TMEM57ENSG00000204178.5247.77170365.15240-0.559502.931301.82710HepG2CSTF2
TMEM57ENSG00000204178.5474.40650601.15290-0.341602.024101.43330HepG2DDX21
TMEM57ENSG00000204178.5739.50000588.006200.330602.144301.35090HepG2DDX24
TMEM57ENSG00000204178.5904.493701247.87650-0.464303.522102.82550HepG2DDX3X
TMEM57ENSG00000204178.51199.08640863.377300.473804.159902.92670HepG2DDX5
TMEM57ENSG00000204178.5762.933801071.95040-0.490603.348502.67590HepG2DDX6
TMEM57ENSG00000204178.5393.82050537.21540-0.448004.293703.51410HepG2DNAJC2
TMEM57ENSG00000204178.5795.798201030.49320-0.372902.408301.85360HepG2EIF2S1
TMEM57ENSG00000204178.5384.92000572.73650-0.573304.794303.35180HepG2FASTKD2
TMEM57ENSG00000204178.5821.576301149.01650-0.483903.827003.02360HepG2FXR1
TMEM57ENSG00000204178.5593.647201065.88230-0.844409.110107.93750HepG2G3BP1
TMEM57ENSG00000204178.5896.607801131.56940-0.335802.134101.35760HepG2G3BP2
TMEM57ENSG00000204178.5475.24090689.65340-0.537206.400804.99400HepG2HDGF
TMEM57ENSG00000204178.5416.54790547.15710-0.393502.372001.77030HepG2HNRNPA1
TMEM57ENSG00000204178.5712.813901079.30010-0.598505.818604.83440HepG2HNRNPK
TMEM57ENSG00000204178.5699.07430847.93980-0.278502.532201.88520HepG2HNRNPL
TMEM57ENSG00000204178.51025.79580750.433700.450803.341202.65640HepG2HNRNPLL
TMEM57ENSG00000204178.5501.29820604.59850-0.270301.865801.35890HepG2HNRNPU
TMEM57ENSG00000204178.5702.575701183.07810-0.751807.666106.63670HepG2NCBP2
TMEM57ENSG00000204178.5988.60130665.426100.571005.228504.21430HepG2NSUN2
TMEM57ENSG00000204178.5792.082201028.62050-0.377004.384703.65030HepG2PCBP1
TMEM57ENSG00000204178.5662.19530539.251400.296202.111601.46080HepG2PPIL4
TMEM57ENSG00000204178.5627.307201046.62770-0.7385014.0612013.01480HepG2PTBP1
TMEM57ENSG00000204178.5755.42630935.42430-0.308303.151702.52860HepG2PUM1
TMEM57ENSG00000204178.5511.36950735.78210-0.524906.543305.66720HepG2PUS1
TMEM57ENSG00000204178.5585.012001133.59220-0.9544018.3801016.96940HepG2QKI
TMEM57ENSG00000204178.51051.28100778.478300.433304.806004.17050HepG2RBM22
TMEM57ENSG00000204178.5745.926801164.82290-0.6430010.812409.87360HepG2NELFE
TMEM57ENSG00000204178.5737.675801084.82580-0.556408.381807.39590HepG2RECQL
TMEM57ENSG00000204178.5976.55460757.298500.366702.816402.12800HepG2RPLP0
TMEM57ENSG00000204178.5642.95980538.414500.255901.857901.31310HepG2SAFB2
TMEM57ENSG00000204178.5962.06510742.762800.373102.594901.91040HepG2SF3B1
TMEM57ENSG00000204178.5781.847401089.73220-0.479006.441505.60100HepG2SF3B4
TMEM57ENSG00000204178.5517.18000627.87020-0.279802.262001.67090HepG2SMN1
TMEM57ENSG00000204178.51133.30170826.460400.455402.236601.53750HepG2SNRNP70
TMEM57ENSG00000204178.51071.43270879.266900.285102.831202.32560HepG2SRFBP1
TMEM57ENSG00000204178.5580.814301137.42100-0.9696022.4758021.40620HepG2SRSF1
TMEM57ENSG00000204178.5731.24240870.05550-0.250801.851401.32510HepG2SRSF5
TMEM57ENSG00000204178.5804.14260989.46710-0.299202.904202.27070HepG2SUCLG1
TMEM57ENSG00000204178.5933.37420713.976400.386502.984502.01120HepG2SUPT6H
TMEM57ENSG00000204178.5576.080001022.29300-0.8275014.8108013.66660HepG2TAF15
TMEM57ENSG00000204178.5740.24340939.41730-0.343802.786001.94740HepG2TIA1
TMEM57ENSG00000204178.5450.59800587.43470-0.382602.638502.14800HepG2TIAL1
TMEM57ENSG00000204178.51372.35520904.605700.601205.789304.89790HepG2U2AF1
TMEM57ENSG00000204178.5233.87310341.77000-0.547302.689001.94080HepG2UCHL5
TMEM57ENSG00000204178.51297.421001022.705400.343204.440303.59120HepG2UPF1
TMEM57ENSG00000204178.5819.19850987.38350-0.269402.317901.75870HepG2UTP3
TMEM57ENSG00000204178.5403.03850569.47690-0.498702.519201.82500HepG2XRN2
TMEM57ENSG00000204178.51603.569601124.781700.5115011.4532010.52720HepG2ZNF622
TMEM57ENSG00000204178.52096.966901349.773800.635507.710606.81190K562AQR
TMEM57ENSG00000204178.51578.46430976.740300.692408.318406.76640K562BOP1
TMEM57ENSG00000204178.51910.838901359.507500.491002.539301.52930K562CNOT7
TMEM57ENSG00000204178.51324.042901038.548400.350303.106902.27480K562CPSF6
TMEM57ENSG00000204178.52616.200601953.487400.421303.869502.70530K562CELF1
TMEM57ENSG00000204178.52184.790101416.976900.6246014.7014013.31540K562DDX47
TMEM57ENSG00000204178.51007.25950644.670000.643706.615205.15650K562EFTUD2
TMEM57ENSG00000204178.5761.99730484.434000.653403.310902.20220K562EIF3A
TMEM57ENSG00000204178.5967.21800690.282800.486603.395602.24050K562EIF3D
TMEM57ENSG00000204178.51109.83160732.906900.598506.569005.31240K562EIF4A3
TMEM57ENSG00000204178.5866.87950660.013900.393203.858802.45710K562EIF4B
TMEM57ENSG00000204178.51448.357501165.925800.312802.310101.53470K562FIP1L1
TMEM57ENSG00000204178.51472.031201056.711500.478104.465103.37610K562FMR1
TMEM57ENSG00000204178.51195.57110895.664100.416603.073402.10430K562FTO
TMEM57ENSG00000204178.51003.74150762.190800.397104.158803.43930K562FXR1
TMEM57ENSG00000204178.51171.57620809.897400.532503.543002.72080K562G3BP2
TMEM57ENSG00000204178.51390.510601042.311100.415705.134803.60910K562GLRX3
TMEM57ENSG00000204178.51311.88760991.552700.403803.511202.62050K562GPKOW
TMEM57ENSG00000204178.5974.74100714.507200.448003.720303.04130K562HNRNPC
TMEM57ENSG00000204178.51849.473801241.140200.575303.055401.55230K562ILF2
TMEM57ENSG00000204178.52005.623901696.152300.241702.196201.47170K562KIF1C
TMEM57ENSG00000204178.51216.10600846.676600.522303.494502.43020K562KRR1
TMEM57ENSG00000204178.51204.78410983.033500.293402.304001.46860K562MATR3
TMEM57ENSG00000204178.51330.55160967.868300.459004.666503.50840K562METAP2
TMEM57ENSG00000204178.52231.076401693.718900.397404.223602.83070K562MSI2
TMEM57ENSG00000204178.51085.00960731.863800.568006.875404.97360K562NCBP2
TMEM57ENSG00000204178.52392.295801737.958600.460905.417803.27530K562NOL12
TMEM57ENSG00000204178.51801.694501306.090500.464002.444501.30330K562PABPC1
TMEM57ENSG00000204178.51122.47290876.448400.356802.667601.70700K562PCBP2
TMEM57ENSG00000204178.51712.771901233.704500.473203.944202.95070K562PCBP3
TMEM57ENSG00000204178.5929.90010697.713000.414303.419101.80990K562PHF6
TMEM57ENSG00000204178.51361.89830946.305100.525106.690105.45480K562POLR2G
TMEM57ENSG00000204178.51020.27530627.337200.701507.373006.15160K562PRPF8
TMEM57ENSG00000204178.51168.33580956.953700.287802.269901.66030K562PTBP1
TMEM57ENSG00000204178.52352.519501733.712800.440204.108603.12060K562PUF60
TMEM57ENSG00000204178.52197.249801843.832700.252902.527101.50890K562PUM1
TMEM57ENSG00000204178.51900.908101544.386100.299603.292502.65440K562RBM15
TMEM57ENSG00000204178.5991.36150767.856300.368502.831701.48590K562RBM25
TMEM57ENSG00000204178.5864.52610639.040000.435902.765801.94970K562RPS19
TMEM57ENSG00000204178.51258.34150871.729400.529505.153503.18300K562SDAD1
TMEM57ENSG00000204178.5849.44570536.845100.661904.273702.29270K562SERBP1
TMEM57ENSG00000204178.51774.043501201.471400.562107.535606.24100K562SF3A3
TMEM57ENSG00000204178.51421.03790943.021600.591505.214103.85690K562SF3B1
TMEM57ENSG00000204178.51047.78340841.833600.315602.580701.75770K562SF3B4
TMEM57ENSG00000204178.52173.885601249.353300.799003.786202.26450K562SNRNP200
TMEM57ENSG00000204178.51516.711701230.937000.301104.049802.93780K562SRPK2
TMEM57ENSG00000204178.51359.313401077.137800.335603.171201.54360K562SRSF9
TMEM57ENSG00000204178.5989.94270607.445300.704506.659905.03050K562SUPV3L1
TMEM57ENSG00000204178.51251.94890949.152500.399404.120803.11290K562SYNCRIP
TMEM57ENSG00000204178.51170.50210784.697000.576804.799503.28110K562U2AF1
TMEM57ENSG00000204178.51381.92970810.537900.7696013.4427011.65500K562U2AF2
TMEM57ENSG00000204178.5859.84740642.882400.419402.939701.88330K562UCHL5
TMEM57ENSG00000204178.51677.565401148.763000.5462011.9400010.32580K562WDR43
TMEM57ENSG00000204178.51909.282901520.541800.328302.836001.96060K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM57 is not available on ENCORE database.





6 RBPs can affect the splicing of TMEM57 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM57ENSG00000204178.5chr1+257831432578332225780749257808732578488125785383-0.131000.000210.09799excludedK562TAF15
SETMEM57ENSG00000204178.5chr1+257831432578332225780749257808732578488125785383-0.117000.000880.01899excludedK562SF3B4
SETMEM57ENSG00000204178.5chr1+257831432578332225780749257808732578488125785383-0.169000.000000.00000excludedK562AQR
SETMEM57ENSG00000204178.5chr1+257831432578332225780749257808732578488125785383-0.215000.000000.00000excludedK562U2AF1
SETMEM57ENSG00000204178.5chr1+257831432578332225780749257808732578488125785383-0.121000.000210.00546excludedK562U2AF2
A3SSTMEM57ENSG00000204178.5chr1+2581787425818075258179002581807525815663258157840.093000.000000.00000longerK562AQR
MXETMEM57ENSG00000204178.5chr1+25784881257853832581060625810765257831432578332225812103258122860.181000.005700.052421includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM57 is not avaliable on ENCORE database.