TFG

General Information

Gene Name       : TFG
Gene ID             : ENSG00000114354.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TFG)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TFGENSG00000114354.1364.8071.0767.94ENCSR000AEF
HepG2TFGENSG00000114354.1368.3493.2580.80ENCSR985KAT
K562TFGENSG00000114354.1379.0296.0387.53ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TFG is not avaliable on ENCORE database.



Proteins bound to RNA
  • TFG RNA is bound by 33 proteins.  







eCLIP assay for TFG is not avaliable on ENCORE database.





33 proteins are bound to TFG RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3100467618100467666+3'-UTR4.8227315.18786HepG2SUB1
chr3100467764100467802+3'-UTR4.7142417.94032K562PUM2
chr3100467534100467619+3'-UTR3.682515.99919HepG2DDX55
chr3100467713100467793+3'-UTR3.440083.23424HepG2FUBP3
chr3100428986100429078+5'-UTR,intron-Distal5.0939128.80940K562RBFOX2
chr3100428764100428876+5'-UTR,intron-Distal,intron-Proximal5.6180512.35127HepG2PRPF4
chr3100428902100428962+5'-UTR,intron-Distal3.302935.12435HepG2PRPF4
chr3100428332100428410+5'-UTR,intron-Distal,intron-Proximal3.579469.45243K562CSTF2T
chr3100428923100428977+5'-UTR,intron-Distal3.430663.40641HepG2GTF2F1
chr3100428762100428892+5'-UTR,intron-Distal,intron-Proximal6.9885920.22085K562GTF2F1
chr3100428759100428830+5'-UTR,intron-Distal,intron-Proximal5.8625051.03512HepG2FAM120A
chr3100428492100428511+5'-UTR,intron-Distal3.347759.01971K562YBX3
chr3100428764100428850+5'-UTR,intron-Distal,intron-Proximal5.9018233.97570K562RBFOX2
chr3100428760100428852+5'-UTR,intron-Distal,intron-Proximal3.662753.48042HepG2NKRF
chr3100428949100429032+5'-UTR,intron-Distal4.083375.10749K562FTO
chr3100428510100428568+5'-UTR,intron-Distal,intron-Proximal4.809067.35577K562PUM2
chr3100428841100428900+5'-UTR,intron-Distal5.238929.09450HepG2CSTF2T
chr3100428850100428894+5'-UTR,intron-Distal5.9633317.05852HepG2RBFOX2
chr3100432485100432553+5'-UTR,CDS,intron-Proximal3.159724.68144K562DDX3X
chr3100432507100432557+5'-UTR,CDS3.145367.65762K562YBX3
chr3100428876100428902+5'-UTR,intron-Distal5.4344610.24558K562CSTF2T
chr3100428850100428902+5'-UTR,intron-Distal6.2247517.19756K562RBFOX2
chr3100428849100428876+5'-UTR,intron-Distal4.6918013.44603K562CSTF2T
chr3100428925100428970+5'-UTR,intron-Distal4.996417.20890K562GTF2F1
chr3100428843100428879+5'-UTR,intron-Distal3.255413.68010HepG2GTF2F1
chr3100428975100429075+5'-UTR,intron-Distal4.3614620.07119K562CSTF2T
chr3100432484100432497+5'-UTR,intron-Proximal4.366086.47483K562PUM2
chr3100428787100428840+5'-UTR,intron-Distal4.794414.97583HepG2GTF2F1
chr3100428765100428888+5'-UTR,intron-Distal5.9238211.96005K562FAM120A
chr3100428761100428892+5'-UTR,intron-Distal,intron-Proximal5.4406249.01394K562DROSHA
chr3100428985100429066+5'-UTR,intron-Distal4.045415.76537HepG2PCBP2
chr3100428477100428565+5'-UTR,intron-Distal4.185239.06301K562DDX3X
chr3100429004100429062+5'-UTR,intron-Distal5.504018.25763HepG2RBFOX2
chr3100428847100428884+5'-UTR,intron-Distal4.6250811.82376HepG2FAM120A
chr3100428779100428847+5'-UTR,intron-Distal5.7282531.03576K562CSTF2T
chr3100428762100428849+5'-UTR,intron-Distal,intron-Proximal5.8494318.92497K562FASTKD2
chr3100428781100428880+5'-UTR,intron-Distal3.791365.80201HepG2DROSHA
chr3100428770100428888+5'-UTR,intron-Distal4.934373.71862K562DDX42
chr3100428848100428888+5'-UTR,intron-Distal4.350154.01425K562AKAP8L
chr3100428511100428561+5'-UTR,intron-Distal3.758596.85451K562YBX3
chr3100428434100428493+5'-UTR,intron-Distal5.364436.75419HepG2DDX3X
chr3100428775100428848+5'-UTR,intron-Distal3.6347210.22208K562AKAP8L
chr3100428920100428965+5'-UTR,intron-Distal3.834819.07337HepG2FAM120A
chr3100428910100428973+5'-UTR,intron-Distal5.3003819.97307HepG2RBFOX2
chr3100428464100428492+5'-UTR,intron-Distal3.746379.88356K562YBX3
chr3100429004100429054+5'-UTR,intron-Distal4.883555.63094K562GTF2F1
chr3100428973100429004+5'-UTR,intron-Distal5.257389.61270HepG2RBFOX2
chr3100428378100428477+5'-UTR,intron-Distal3.221537.39484K562DDX3X
chr3100432497100432554+5'-UTR,CDS4.0299213.98238K562PUM2
chr3100428760100428850+5'-UTR,intron-Distal,intron-Proximal5.8959162.20119HepG2RBFOX2
chr3100428592100428642+5'-UTR,intron-Distal,intron-Proximal3.656576.90022HepG2RBFOX2
chr3100428920100428968+5'-UTR,intron-Distal4.151517.48189HepG2CSTF2T
chr3100428780100428841+5'-UTR,intron-Distal4.6894413.53287HepG2CSTF2T
chr3100428503100428565+5'-UTR,intron-Distal6.7472011.95715HepG2DDX3X
chr3100428902100428986+5'-UTR,intron-Distal6.7464432.39184K562RBFOX2
chr3100428849100428907+5'-UTR,intron-Distal3.142333.54287K562HNRNPU
chr3100428925100428975+5'-UTR,intron-Distal5.9030416.97304K562CSTF2T
chr3100428830100428847+5'-UTR,intron-Distal4.4498315.90032HepG2FAM120A
chr3100438820100438902+CDS3.7711810.64917HepG2BCLAF1
chr3100463676100463763+CDS,intron-Proximal4.656255.59066HepG2IGF2BP1
chr3100432633100432694+CDS4.100168.17198K562LIN28B
chr3100463757100463776+CDS,intron-Proximal4.331943.74511K562IGF2BP1
chr3100463675100463764+CDS,intron-Proximal3.779816.96130K562IGF2BP2
chr3100447620100447706+CDS,intron-Proximal4.005967.73111HepG2GRWD1
chr3100447699100447745+CDS,intron-Proximal3.475904.41130K562AQR
chr3100466992100467069+CDS,intron-Proximal3.685117.41930K562IGF2BP1
chr3100447652100447664+CDS5.648699.93069K562IGF2BP1
chr3100432618100432712+CDS3.4782710.65310HepG2BCLAF1
chr3100447555100447620+CDS,intron-Proximal3.314703.79741HepG2GRWD1
chr3100466997100467159+CDS3.089969.25777K562IGF2BP2
chr3100463764100463810+CDS,intron-Proximal5.157478.26505HepG2PRPF8
chr3100463774100463795+CDS,intron-Proximal3.114673.49168K562AQR
chr3100467165100467257+CDS4.782657.48557K562IGF2BP1
chr3100467186100467248+CDS3.035826.10994K562IGF2BP2
chr3100467102100467160+CDS3.382555.15873HepG2IGF2BP1
chr3100463644100463702+CDS,intron-Proximal4.684459.27512K562GPKOW
chr3100432619100432691+CDS3.515505.31167HepG2GRWD1
chr3100455418100455464+CDS,intron-Proximal3.737664.54534K562IGF2BP2
chr3100438813100438879+CDS,intron-Proximal3.598513.04123K562LIN28B
chr3100432557100432583+CDS3.169647.87605K562YBX3
chr3100455468100455553+CDS,intron-Proximal3.587506.44105HepG2IGF2BP1
chr3100463617100463720+CDS,intron-Proximal4.5928513.13232K562SF3B4
chr3100455534100455598+CDS,intron-Proximal3.8000410.64040HepG2PRPF8
chr3100447612100447698+CDS3.7555911.46750HepG2BCLAF1
chr3100455464100455559+CDS,intron-Proximal5.0552013.59476K562IGF2BP2
chr3100451350100451403+CDS,intron-Proximal3.393063.57974K562IGF2BP1
chr3100466995100467102+CDS3.7564411.03641HepG2IGF2BP1
chr3100467168100467254+CDS4.195256.34884HepG2IGF2BP1
chr3100447664100447702+CDS5.9646414.34960K562IGF2BP1
chr3100453475100453578+intron-Distal3.204803.39857HepG2HNRNPM
chr3100462155100462201+intron-Distal4.199065.56048K562KHSRP
chr3100448276100448363+intron-Distal3.526488.26817K562KHSRP
chr3100451574100451653+intron-Distal,intron-Proximal5.156595.82778K562PRPF8
chr3100447748100447893+intron-Distal,intron-Proximal3.114144.65130K562PRPF8
chr3100448827100448896+intron-Distal4.999146.83215HepG2U2AF2
chr3100450080100450177+intron-Distal3.441773.07751K562KHSRP
chr3100448224100448272+intron-Distal3.119493.31157HepG2KHSRP
chr3100448738100448799+intron-Distal3.812535.18845HepG2U2AF2
chr3100466781100466872+intron-Distal3.844266.57673K562KHSRP
chr3100452185100452237+intron-Distal4.038095.95946K562KHSRP
chr3100462133100462154+intron-Distal3.017593.69044K562KHSRP
chr3100447768100447828+intron-Distal,intron-Proximal3.758623.19904K562TIA1
chr3100462104100462133+intron-Distal3.119844.46008K562KHSRP
chr3100452512100452644+intron-Distal3.426095.21690HepG2HNRNPM
chr3100462082100462104+intron-Distal3.625065.96041K562KHSRP
chr3100452145100452200+intron-Distal3.903383.31110K562TIA1
chr3100448729100448822+intron-Distal3.106595.82594K562KHSRP
chr3100452367100452427+intron-Distal3.260653.96958K562KHSRP
chr3100433933100434032+intron-Distal4.873619.11780K562QKI
chr3100433959100434031+intron-Distal5.302779.03229HepG2QKI
chr3100461969100462082+intron-Distal4.666779.20471K562KHSRP
chr3100463795100463818+intron-Proximal3.812114.49024K562AQR
chr3100451524100451551+intron-Proximal6.177245.35117HepG2PRPF8
chr3100455352100455412+intron-Proximal5.2597810.67905HepG2SF3B4
chr3100451539100451613+intron-Proximal4.710739.63817K562TIA1
chr3100455350100455401+intron-Proximal5.7661230.79701K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TFG is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TFG is not available on ENCORE database.

  • 66 RBPs can affect the levels of TFG.  








The Knockdown/knockout RNA-Seq assay for TFG is not available on ENCORE database.





66 RBPs can affect the gene expression of TFG :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TFGENSG00000114354.81492.732801697.25730-0.185201.894101.37340HepG2ACO1
TFGENSG00000114354.8881.985802475.13660-1.4887028.4118026.92200HepG2AKAP1
TFGENSG00000114354.81253.911201705.28190-0.443607.320506.13770HepG2AKAP8L
TFGENSG00000114354.82003.735102836.35210-0.501306.562504.50410HepG2ATP5C1
TFGENSG00000114354.81977.909502505.46900-0.341105.575504.65950HepG2AUH
TFGENSG00000114354.82644.939503388.57400-0.357403.238102.59710HepG2BOP1
TFGENSG00000114354.82256.931602554.69130-0.178802.205201.53180HepG2DAZAP1
TFGENSG00000114354.8982.073601569.74770-0.6766017.7095016.02830HepG2DDX19B
TFGENSG00000114354.81786.256701358.027800.395303.689602.91530HepG2DDX21
TFGENSG00000114354.81207.517801606.39960-0.411802.713901.94600HepG2DDX55
TFGENSG00000114354.81467.287801736.63870-0.243102.354801.69960HepG2DNAJC21
TFGENSG00000114354.82120.469202876.62430-0.440008.826707.85490HepG2ETF1
TFGENSG00000114354.81198.867602025.16650-0.756408.911207.75300HepG2G3BP1
TFGENSG00000114354.82882.298103526.73360-0.291101.876401.34180HepG2GPKOW
TFGENSG00000114354.81053.605901463.67940-0.474302.730801.62650HepG2GRSF1
TFGENSG00000114354.81567.718301950.20240-0.315002.611701.93610HepG2HNRNPC
TFGENSG00000114354.81944.642602327.10100-0.259004.202903.38510HepG2HNRNPL
TFGENSG00000114354.81424.270001937.30840-0.443808.344007.33160HepG2HNRNPU
TFGENSG00000114354.81655.317602058.50180-0.314502.164701.55930HepG2IGF2BP2
TFGENSG00000114354.81775.103802196.18670-0.307101.872001.34780HepG2MATR3
TFGENSG00000114354.82044.671502533.23150-0.309103.524302.66400HepG2NOL12
TFGENSG00000114354.81849.411002281.81390-0.303104.329403.38610HepG2PRPF4
TFGENSG00000114354.82226.572502567.07220-0.205302.943602.33610HepG2PUM1
TFGENSG00000114354.81963.078602245.24740-0.193802.089101.60510HepG2NELFE
TFGENSG00000114354.81581.698502091.05920-0.402806.937306.02610HepG2RECQL
TFGENSG00000114354.81741.594502727.42930-0.6471010.128508.96130HepG2RPLP0
TFGENSG00000114354.8938.257301637.44170-0.8034010.700308.62720HepG2RPS5
TFGENSG00000114354.83648.039202551.004900.516003.793202.99860HepG2SF3A3
TFGENSG00000114354.82779.526003331.40610-0.261301.970101.36870HepG2SF3B1
TFGENSG00000114354.81540.893302011.93210-0.384807.955206.95410HepG2SMN1
TFGENSG00000114354.82953.202102192.426900.429709.100408.35360HepG2SRSF1
TFGENSG00000114354.81611.408102387.67100-0.5673013.1745011.94420HepG2SRSF5
TFGENSG00000114354.81450.271001783.62110-0.298504.254503.59790HepG2SRSF9
TFGENSG00000114354.82739.715802357.768900.216502.806602.29150HepG2SSB
TFGENSG00000114354.82232.742502715.40990-0.282404.719103.94480HepG2SUCLG1
TFGENSG00000114354.82760.321502143.100100.365003.936102.82640HepG2SUPT6H
TFGENSG00000114354.8960.769901970.52610-1.0363030.7484029.14880HepG2TAF15
TFGENSG00000114354.81759.062302500.74500-0.507604.543203.45200HepG2UBE2L3
TFGENSG00000114354.8705.08550944.68180-0.422002.908902.13240HepG2UCHL5
TFGENSG00000114354.81859.765302251.87880-0.276004.441803.62200HepG2ZC3H8
TFGENSG00000114354.83295.798802488.153900.4055011.1952010.27710HepG2ZNF622
TFGENSG00000114354.85735.143704063.770300.4969012.8887011.76140K562AGGF1
TFGENSG00000114354.84410.536703252.200200.439405.206404.44560K562AQR
TFGENSG00000114354.82025.373201613.976000.327502.567201.55990K562CCAR1
TFGENSG00000114354.82879.356903681.34590-0.354506.477804.74610K562CPEB4
TFGENSG00000114354.85535.770804549.871300.282903.873502.81500K562DKC1
TFGENSG00000114354.83450.230703986.68240-0.208502.528301.62650K562EIF4G2
TFGENSG00000114354.82778.827102176.076800.352602.728001.61120K562FKBP4
TFGENSG00000114354.82018.394002316.18690-0.198501.893201.37390K562FXR1
TFGENSG00000114354.82063.302502979.93180-0.530307.996206.69980K562GRSF1
TFGENSG00000114354.82045.328302506.40310-0.293302.704102.11270K562HNRNPC
TFGENSG00000114354.85443.345304487.376000.278502.925002.07460K562KIF1C
TFGENSG00000114354.82223.598902703.90880-0.282102.470301.67320K562MAGOH
TFGENSG00000114354.82139.096402698.45040-0.335103.540902.48320K562MATR3
TFGENSG00000114354.81660.678102768.97750-0.7376013.9470012.30120K562MTPAP
TFGENSG00000114354.84802.484903523.601500.446603.434902.42990K562NAA15
TFGENSG00000114354.81844.489302405.84180-0.383303.874302.71260K562PCBP2
TFGENSG00000114354.82113.708502621.00830-0.310302.302601.57230K562POLR2G
TFGENSG00000114354.88160.045504193.148700.960408.786507.86750K562PUS1
TFGENSG00000114354.85990.360204085.976500.551905.678804.85420K562RBM15
TFGENSG00000114354.82082.469302519.07990-0.274602.145401.40990K562RBM22
TFGENSG00000114354.82635.374102050.356000.362004.264303.02920K562RCC2
TFGENSG00000114354.82070.594402650.90590-0.356402.983101.84360K562NELFE
TFGENSG00000114354.85279.219302662.534100.987402.582401.43550K562SF1
TFGENSG00000114354.83703.454603035.749800.286703.976803.00860K562SF3A3
TFGENSG00000114354.85804.234703059.654200.923602.740201.51770K562SNRNP200
TFGENSG00000114354.82841.014902161.483400.394303.324602.29240K562TIAL1
TFGENSG00000114354.83094.349502296.323700.430205.121503.73720K562TRIM56
TFGENSG00000114354.83686.804902972.642400.310505.142803.39820K562TROVE2
TFGENSG00000114354.82850.419302185.414200.383202.798301.69820K562U2AF1
TFGENSG00000114354.83679.816903262.268200.173702.061901.43580K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TFG is not available on ENCORE database.





3 RBPs can affect the splicing of TFG :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETFGENSG00000114354.8chr3+1004298141004299121004283151004285651004324861004327130.160000.000000.00041includedHepG2HNRNPL
SETFGENSG00000114354.8chr3+1004298141004299121004283151004285651004324861004327130.066000.000020.00356includedK562HNRNPL
SETFGENSG00000114354.8chr3+1004298141004299121004283151004285651004324861004327130.271000.000000.00019includedK562HNRNPC
A5SSTFGENSG00000114354.8chr3+1004554191004555601004554191004555481004636761004637750.115000.001590.02761longerK562AQR
MXETFGENSG00000114354.8chr3+1004324861004327131004475551004477021004282041004282751004513511004515160.061000.000530.005231includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TFG is not avaliable on ENCORE database.