TBC1D17

General Information

Gene Name       : TBC1D17
Gene ID             : ENSG00000104946.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TBC1D17)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBC1D17ENSG00000104946.125.467.396.42ENCSR000AEF
HepG2TBC1D17ENSG00000104946.1211.576.879.22ENCSR985KAT
K562TBC1D17ENSG00000104946.128.425.857.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBC1D17 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBC1D17 RNA is bound by 13 proteins.  







eCLIP assay for TBC1D17 is not avaliable on ENCORE database.





13 proteins are bound to TBC1D17 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195038611550386150+3'-UTR,CDS,intron-Proximal4.402355.32242HepG2PABPN1
chr195038450450384566+3'-UTR,CDS,intron-Proximal3.500084.88100K562AQR
chr195039149050391571+3'-UTR,CDS3.577817.01634HepG2PABPN1
chr195038613150386182+3'-UTR,CDS,intron-Proximal4.784526.35567HepG2PRPF8
chr195038448050384563+3'-UTR,CDS,intron-Proximal4.390044.82767HepG2SF3B4
chr195038447650384602+3'-UTR,CDS,intron-Proximal5.361685.40008K562SF3B4
chr195038559350385648+3'-UTR,CDS3.412705.86107HepG2PPIG
chr195038611550386142+3'-UTR,CDS4.895155.56813HepG2PPIG
chr195038258950382688+5'-UTR,CDS,intron-Distal3.250703.78281HepG2SRSF1
chr195038346150383559+5'-UTR,CDS,intron-Proximal3.731404.44625HepG2SF3B4
chr195038365850383673+5'-UTR,CDS,intron-Proximal4.140146.80869K562AQR
chr195038263750382722+5'-UTR,intron-Distal4.902275.68196HepG2BCLAF1
chr195038275150382792+5'-UTR,intron-Distal,intron-Proximal5.469288.04585HepG2PRPF8
chr195038365750383667+5'-UTR,CDS,intron-Proximal3.773994.51097HepG2PRPF8
chr195038262950382680+5'-UTR,intron-Distal3.507524.93175HepG2GRWD1
chr195039138850391446+CDS,intron-Proximal5.374888.34710K562AQR
chr195039100450391084+CDS3.577817.01634HepG2PABPN1
chr195038144650381498+CDS,intron-Distal4.262459.56105HepG2PPIG
chr195038252650382601+CDS,intron-Distal,intron-Proximal4.220583.71613K562UCHL5
chr195038626250386312+CDS3.517716.13978HepG2PPIG
chr195038175450381808+CDS,intron-Proximal4.482155.42152HepG2GRWD1
chr195038791550387980+CDS,intron-Proximal4.635185.90013HepG2PABPN1
chr195039097350390998+CDS,intron-Proximal3.356846.82013HepG2PPIG
chr195038146850381500+CDS,intron-Distal,intron-Proximal4.033764.23295HepG2GRWD1
chr195039108150391137+CDS,intron-Proximal3.472747.54792HepG2PRPF8
chr195038175350381813+CDS,intron-Proximal4.4925110.10144HepG2PPIG
chr195039079850390829+CDS3.367163.77473HepG2PABPN1
chr195039079150390816+CDS3.954626.98305HepG2PPIG
chr195038146050381499+CDS,intron-Distal,intron-Proximal4.094593.43980K562ZNF622
chr195038135950381499+CDS,intron-Distal,intron-Proximal4.671756.14390HepG2NCBP2
chr195038685050386909+CDS,intron-Proximal4.355647.08280K562SF3B4
chr195039081650390831+CDS,intron-Proximal3.999727.55042HepG2PPIG
chr195038633150386377+CDS,intron-Proximal5.199635.65342K562AQR
chr195038140650381446+CDS,intron-Distal3.930964.41267HepG2PPIG
chr195038799450388051+CDS,intron-Proximal4.398278.11807HepG2PRPF8
chr195038182650381868+CDS,intron-Proximal4.2172611.70689HepG2PRPF8
chr195038194850381993+intron-Distal4.023583.73926K562RBM15
chr195039121150391379+intron-Distal,intron-Proximal4.181383.91671HepG2RBFOX2
chr195038679650386907+intron-Distal,intron-Proximal3.333523.59805HepG2SF3B4
chr195038425650384358+intron-Distal4.081813.36385K562UCHL5
chr195038207950382119+intron-Distal4.305053.81597K562RBM15
chr195039085250390893+intron-Proximal3.837775.05356HepG2PRPF8
chr195039109150391134+intron-Proximal4.017064.88100K562AQR
chr195038366750383705+intron-Proximal3.646256.41344HepG2PRPF8
chr195038762850387702+intron-Proximal3.624067.26133HepG2PRPF8
chr195038367450383712+intron-Proximal4.895799.04436K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBC1D17 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBC1D17 is not available on ENCORE database.

  • 95 RBPs can affect the levels of TBC1D17.  








The Knockdown/knockout RNA-Seq assay for TBC1D17 is not available on ENCORE database.





95 RBPs can affect the gene expression of TBC1D17 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBC1D17ENSG00000104946.6524.74050305.880700.778506.786805.31150HepG2ADAR
TBC1D17ENSG00000104946.6844.63470574.264300.556507.313106.13090HepG2AKAP8L
TBC1D17ENSG00000104946.6840.49350574.217100.549504.156703.20250HepG2ASCC1
TBC1D17ENSG00000104946.6798.91530668.545600.256901.928901.33670HepG2AUH
TBC1D17ENSG00000104946.6540.57970351.022300.622803.572702.50890HepG2BCCIP
TBC1D17ENSG00000104946.6761.49180438.164200.797308.604107.61800HepG2BOP1
TBC1D17ENSG00000104946.6742.26710539.184900.461103.241001.91410HepG2BUD13
TBC1D17ENSG00000104946.6827.57950545.561300.601104.911003.89660HepG2CIRBP
TBC1D17ENSG00000104946.6947.45530571.449300.7293014.2109012.94760HepG2CKAP4
TBC1D17ENSG00000104946.6642.43720378.190700.764304.477403.50060HepG2CNOT7
TBC1D17ENSG00000104946.6702.15500402.242000.803608.011606.89330HepG2CPSF6
TBC1D17ENSG00000104946.6734.30790566.193800.375003.803702.95790HepG2DAZAP1
TBC1D17ENSG00000104946.6462.11310314.102500.556904.303902.88300HepG2DDX1
TBC1D17ENSG00000104946.6472.87170328.153200.527003.531802.77290HepG2DDX21
TBC1D17ENSG00000104946.61048.45920664.741100.657305.413504.56440HepG2DDX3X
TBC1D17ENSG00000104946.6732.47610542.929200.431902.989201.94310HepG2DDX5
TBC1D17ENSG00000104946.6703.79630546.862600.363903.053302.34580HepG2DKC1
TBC1D17ENSG00000104946.6485.50640307.984500.656506.297305.27040HepG2DNAJC21
TBC1D17ENSG00000104946.6400.49910305.316300.391402.792802.13830HepG2DNAJC2
TBC1D17ENSG00000104946.6996.02270548.934000.859407.632906.68420HepG2EIF2S1
TBC1D17ENSG00000104946.6816.44240606.520600.428702.429001.82840HepG2EIF4A3
TBC1D17ENSG00000104946.6983.54910590.754300.735303.754402.95950HepG2EIF4B
TBC1D17ENSG00000104946.61157.41400767.606000.592408.958707.98130HepG2ETF1
TBC1D17ENSG00000104946.6953.55820567.817900.747807.048406.00940HepG2G3BP1
TBC1D17ENSG00000104946.61262.13470455.927301.4689024.7300023.02670HepG2GPKOW
TBC1D17ENSG00000104946.6482.23490310.935700.633004.580803.77760HepG2HNRNPA1
TBC1D17ENSG00000104946.6458.40150345.875500.406302.142701.52310HepG2HNRNPC
TBC1D17ENSG00000104946.6606.81230428.964500.500305.194504.24920HepG2HNRNPF
TBC1D17ENSG00000104946.61102.44610435.103901.3412022.4814020.96080HepG2HNRNPLL
TBC1D17ENSG00000104946.6465.64610343.587500.438503.440402.77220HepG2HNRNPU
TBC1D17ENSG00000104946.6653.93560422.411200.630406.624105.54650HepG2IGF2BP1
TBC1D17ENSG00000104946.61241.94420577.108801.1056016.3937014.91540HepG2IGF2BP2
TBC1D17ENSG00000104946.61060.49260692.809300.614103.678502.72180HepG2LARP4
TBC1D17ENSG00000104946.6841.68890612.520200.458403.006002.32320HepG2MAGOH
TBC1D17ENSG00000104946.6683.26640443.848700.622302.185101.33150HepG2MTPAP
TBC1D17ENSG00000104946.61121.26530630.352600.830808.840707.74390HepG2NCBP2
TBC1D17ENSG00000104946.6455.45920298.346700.610202.953001.45350HepG2NOLC1
TBC1D17ENSG00000104946.6604.79830316.934900.932205.043903.54080HepG2NONO
TBC1D17ENSG00000104946.6542.85290385.835800.492502.986702.20990HepG2NSUN2
TBC1D17ENSG00000104946.6565.45330345.764600.709503.591902.57070HepG2PABPC1
TBC1D17ENSG00000104946.6781.63120561.156900.478003.193902.41980HepG2PABPC4
TBC1D17ENSG00000104946.6867.09820577.940300.585208.193707.24000HepG2PCBP1
TBC1D17ENSG00000104946.6518.06600351.231300.560602.852701.79560HepG2PCBP2
TBC1D17ENSG00000104946.6427.60540306.449700.480503.540002.71640HepG2PPIL4
TBC1D17ENSG00000104946.6589.36940435.593800.436103.818102.92270HepG2PRPF4
TBC1D17ENSG00000104946.61181.68730535.935901.1406021.5009020.05030HepG2PUF60
TBC1D17ENSG00000104946.6777.47180568.502400.451503.924503.12880HepG2PUM2
TBC1D17ENSG00000104946.6794.01830582.211800.447505.227004.42920HepG2PUS1
TBC1D17ENSG00000104946.6806.67120578.026700.480704.227203.40870HepG2RBM25
TBC1D17ENSG00000104946.6534.80540654.47530-0.291301.937201.46640HepG2NELFE
TBC1D17ENSG00000104946.6552.76190333.052100.730803.447402.39270HepG2RPS10
TBC1D17ENSG00000104946.6403.09400298.225400.434602.326101.75700HepG2RPS19
TBC1D17ENSG00000104946.6597.43110380.062000.652404.020703.05570HepG2RPS3A
TBC1D17ENSG00000104946.6434.09450305.969900.504502.776802.13150HepG2SAFB2
TBC1D17ENSG00000104946.61474.93910893.238500.723405.978804.96360HepG2SF3A3
TBC1D17ENSG00000104946.6635.55630430.640700.561404.216303.36190HepG2SF3B1
TBC1D17ENSG00000104946.6527.12180272.458100.952002.882001.53860HepG2SNRNP200
TBC1D17ENSG00000104946.6753.93510479.172700.653803.651002.74930HepG2SNRNP70
TBC1D17ENSG00000104946.6463.03660639.06930-0.464804.154803.60420HepG2SRSF1
TBC1D17ENSG00000104946.6749.80670529.153300.502705.597704.75310HepG2SRSF5
TBC1D17ENSG00000104946.6523.80060421.431000.313602.333101.68970HepG2SRSF7
TBC1D17ENSG00000104946.6420.47330519.92420-0.306302.084501.59150HepG2SRSF9
TBC1D17ENSG00000104946.61312.25570629.126001.0605030.7246029.43580HepG2SSB
TBC1D17ENSG00000104946.6524.03990330.715200.664004.311302.90500HepG2STIP1
TBC1D17ENSG00000104946.6761.76280343.567901.1486011.9300010.68800HepG2SUPV3L1
TBC1D17ENSG00000104946.6357.37430574.44390-0.684707.177406.34730HepG2TAF15
TBC1D17ENSG00000104946.6860.25790424.212001.019908.849007.65630HepG2TARDBP
TBC1D17ENSG00000104946.6351.93170230.278800.611803.120402.06420HepG2TFIP11
TBC1D17ENSG00000104946.6697.33440333.795501.0628016.4719015.43550HepG2TIAL1
TBC1D17ENSG00000104946.6586.35080336.848100.7996011.2028010.18050HepG2TRIM56
TBC1D17ENSG00000104946.6962.53150621.687200.630505.549604.67670HepG2U2AF1
TBC1D17ENSG00000104946.61152.84700316.572501.864508.833306.97400HepG2U2AF2
TBC1D17ENSG00000104946.6364.31120202.953000.843906.163105.02020HepG2UCHL5
TBC1D17ENSG00000104946.6986.66290792.166700.316703.360502.60350HepG2UPF1
TBC1D17ENSG00000104946.6595.35790314.591100.920205.998504.48030HepG2UPF2
TBC1D17ENSG00000104946.6591.82010764.80480-0.369903.143102.51150HepG2UTP3
TBC1D17ENSG00000104946.6547.59880340.439200.685604.343902.96410HepG2XPO5
TBC1D17ENSG00000104946.6589.18580338.205000.800706.248205.17310HepG2XRN2
TBC1D17ENSG00000104946.6602.24500429.872900.486305.003104.14450HepG2ZC3H8
TBC1D17ENSG00000104946.61244.52600871.230800.514409.811808.94050HepG2ZNF622
TBC1D17ENSG00000104946.6840.42680585.462200.521403.591302.43540K562AKAP8
TBC1D17ENSG00000104946.6713.43620554.377600.363802.513901.89060K562AKAP8L
TBC1D17ENSG00000104946.6672.87360486.350900.468203.369902.73520K562AQR
TBC1D17ENSG00000104946.6329.18580238.260200.466302.572401.32070K562BCCIP
TBC1D17ENSG00000104946.6389.99020243.864200.677304.548203.12520K562CCAR1
TBC1D17ENSG00000104946.6353.66380249.352400.504102.556901.32660K562CIRBP
TBC1D17ENSG00000104946.6415.28790301.996200.459502.809901.75980K562DDX3X
TBC1D17ENSG00000104946.6428.83610326.161500.394702.086401.34610K562FIP1L1
TBC1D17ENSG00000104946.670.18360164.52110-1.229105.904504.78550K562G3BP2
TBC1D17ENSG00000104946.6434.89370241.976500.845707.030205.76250K562GPKOW
TBC1D17ENSG00000104946.6591.11460411.959000.520804.675903.50750K562HNRNPU
TBC1D17ENSG00000104946.6327.31970442.19070-0.434002.351001.61320K562HSPD1
TBC1D17ENSG00000104946.6445.42580232.751700.936306.955605.03020K562IGF2BP2
TBC1D17ENSG00000104946.6303.49020206.692400.554102.179201.36160K562KRR1
TBC1D17ENSG00000104946.6349.23110239.059200.546703.502001.97510K562PCBP1
TBC1D17ENSG00000104946.6298.97690217.540600.458602.186001.32160K562PCBP2
TBC1D17ENSG00000104946.6471.06330614.09200-0.382502.743701.31010K562PNPT1
TBC1D17ENSG00000104946.6465.26950693.68410-0.576205.982604.35800K562PUM1
TBC1D17ENSG00000104946.6277.27170170.984200.697303.860202.84490K562SF3B4
TBC1D17ENSG00000104946.6677.62710397.168500.770603.041701.64450K562SFPQ
TBC1D17ENSG00000104946.6309.26750207.286200.577102.298601.38210K562SRFBP1
TBC1D17ENSG00000104946.6372.55000232.908300.677604.274603.40130K562SRSF1
TBC1D17ENSG00000104946.6209.16230321.15080-0.618603.974102.98690K562SYNCRIP
TBC1D17ENSG00000104946.6347.88890227.360400.613503.981902.97470K562TIA1
TBC1D17ENSG00000104946.6418.35850244.892600.772503.676802.55690K562TRIM56
TBC1D17ENSG00000104946.6235.44280164.631900.516002.461801.70320K562U2AF2
TBC1D17ENSG00000104946.6635.49180514.253300.305302.303001.64370K562UPF1
TBC1D17ENSG00000104946.6566.67540440.031900.364802.274901.48050K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBC1D17 is not available on ENCORE database.





10 RBPs can affect the splicing of TBC1D17 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETBC1D17ENSG00000104946.6chr19+5038266250382761503817545038182950383535503836590.293000.000010.00025includedK562SF3B4
SETBC1D17ENSG00000104946.6chr19+5038266250382761503817545038182950383535503836590.123000.000760.04920includedHepG2RBM22
SETBC1D17ENSG00000104946.6chr19+503862295038633350386020503861495038690750387002-0.455000.000000.00001excludedHepG2U2AF1
SETBC1D17ENSG00000104946.6chr19+503862295038633350386020503861495038690750387002-0.327000.000580.00885excludedHepG2U2AF2
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.117000.000940.01165includedK562AQR
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.121000.000430.03243includedHepG2FTO
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.059000.000730.08562includedK562LARP4
SETBC1D17ENSG00000104946.6chr19+5038266250382761503817545038182950383535503836590.166000.000020.00413includedHepG2DDX6
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.126000.000020.00122includedHepG2SF3A3
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.279000.000260.03973includedK562RBM22
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.126000.006620.08965includedK562U2AF2
SETBC1D17ENSG00000104946.6chr19+5038257950382761503817545038182950383535503836590.209000.002070.07023includedK562SF3B1
A3SSTBC1D17ENSG00000104946.6chr19+503914135039157450391487503915745039097450391091-0.054000.000050.00210shorterHepG2U2AF2
A5SSTBC1D17ENSG00000104946.6chr19+5038353550383701503835355038365950384524503847320.156000.004380.06494longerK562AQR
RITBC1D17ENSG00000104946.6chr19+5038776850388015503877685038781650387915503880150.066000.000000.00008includedHepG2RBM22
RITBC1D17ENSG00000104946.6chr19+5038776850388015503877685038781650387915503880150.063000.000390.00282includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBC1D17 is not avaliable on ENCORE database.