SPNS1

General Information

Gene Name       : SPNS1
Gene ID             : ENSG00000169682.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPNS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPNS1ENSG00000169682.171.584.903.24ENCSR000AEF
HepG2SPNS1ENSG00000169682.1739.2318.8629.04ENCSR985KAT
K562SPNS1ENSG00000169682.1727.9714.9621.46ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPNS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPNS1 RNA is bound by 15 proteins.  







eCLIP assay for SPNS1 is not avaliable on ENCORE database.





15 proteins are bound to SPNS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr162899570228995769+3'-UTR,CDS3.450033.27682HepG2LARP4
chr162899558528995752+3'-UTR,CDS4.313385.87389HepG2UPF1
chr162899555128995684+3'-UTR,CDS3.110076.67252HepG2LARP4
chr162899575228995820+3'-UTR,CDS3.822494.69646HepG2UPF1
chr162898640228986482+5'-UTR,CDS,intron-Distal,intron-Proximal4.0181115.69555HepG2RPS3
chr162898615928986270+5'-UTR,CDS,intron-Distal,intron-Proximal4.1426652.75985HepG2DDX3X
chr162898613028986159+5'-UTR,CDS,intron-Distal5.6407021.88064HepG2DDX3X
chr162898612528986138+5'-UTR,CDS,intron-Distal3.696704.08283K562DDX3X
chr162898650028986619+5'-UTR,CDS,intron-Proximal5.6622022.14311HepG2RPS3
chr162898627028986329+5'-UTR,intron-Distal,intron-Proximal4.4388621.94029HepG2DDX3X
chr162898649028986630+5'-UTR,CDS,intron-Proximal3.4206424.97827HepG2DDX3X
chr162898682528986916+CDS,intron-Distal,intron-Proximal3.299017.09156HepG2PRPF8
chr162899272428992814+CDS,intron-Distal,intron-Proximal4.774655.86025HepG2SF3B4
chr162899322728993304+CDS,intron-Distal3.476163.61371K562SND1
chr162899052028990590+CDS,intron-Distal4.057694.01886HepG2LIN28B
chr162899373128993865+CDS,intron-Distal3.8257511.04068HepG2PCBP2
chr162899419228994243+CDS,intron-Distal4.453163.79199HepG2PPIG
chr162899511528995275+CDS,intron-Distal3.404935.50870HepG2IGF2BP3
chr162899075728990843+CDS,intron-Distal,intron-Proximal4.5842121.19792HepG2PRPF8
chr162899422128994287+CDS,intron-Distal,intron-Proximal3.908419.09021HepG2PRPF8
chr162898934528989381+CDS,intron-Distal,intron-Proximal4.354963.49332HepG2PPIG
chr162899384928993927+CDS,intron-Distal,intron-Proximal3.992045.90868HepG2PRPF8
chr162898669628986757+CDS,intron-Proximal4.233476.81564HepG2PRPF8
chr162899462428994683+intron-Distal,intron-Proximal4.648515.93128HepG2PRPF8
chr162898994028989985+intron-Distal4.254323.55787K562PTBP1
chr162898954528989703+intron-Distal4.816117.23552K562HNRNPK
chr162898961528989689+intron-Distal4.8491010.86699HepG2PCBP2
chr162898955828989613+intron-Distal4.293133.89149HepG2HNRNPK
chr162898957228989639+intron-Distal4.952945.11777HepG2DDX59
chr162898966228989734+intron-Distal3.854873.28841HepG2PTBP1
chr162898951028989615+intron-Distal6.3389114.78401HepG2PCBP2
chr162899166428991748+intron-Distal3.375674.14989HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPNS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPNS1 is not available on ENCORE database.

  • 110 RBPs can affect the levels of SPNS1.  








The Knockdown/knockout RNA-Seq assay for SPNS1 is not available on ENCORE database.





110 RBPs can affect the gene expression of SPNS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPNS1ENSG00000169682.131306.55990969.137200.430906.060904.96580HepG2AKAP8L
SPNS1ENSG00000169682.13401.876901034.16510-1.363604.965103.92700HepG2ASCC1
SPNS1ENSG00000169682.131787.86360620.075101.5276039.2301037.45770HepG2BOP1
SPNS1ENSG00000169682.13992.71780360.154201.4627015.4536013.70940HepG2CNOT7
SPNS1ENSG00000169682.13543.77100389.857600.480004.014802.78470HepG2YBX3
SPNS1ENSG00000169682.131192.58570703.283700.761806.976105.87750HepG2DAZAP1
SPNS1ENSG00000169682.13615.51970390.383500.656806.964405.23220HepG2DDX1
SPNS1ENSG00000169682.132625.501301197.163501.1329012.7943011.54050HepG2DDX3X
SPNS1ENSG00000169682.13760.45630382.785400.9902017.1289015.52280HepG2DNAJC21
SPNS1ENSG00000169682.13766.99520379.442401.0152022.4587020.76350HepG2DNAJC2
SPNS1ENSG00000169682.131649.705901092.218400.594802.336201.74700HepG2EIF4A3
SPNS1ENSG00000169682.13464.18430693.82010-0.579906.311405.13780HepG2EIF4G1
SPNS1ENSG00000169682.13615.61020333.453900.884406.326504.63990HepG2GRSF1
SPNS1ENSG00000169682.13514.65180304.844600.755404.842602.97980HepG2HNRNPA0
SPNS1ENSG00000169682.13435.70400297.653800.549602.894901.46140HepG2HNRNPAB
SPNS1ENSG00000169682.13897.52130429.869801.061904.961604.05320HepG2HNRNPC
SPNS1ENSG00000169682.13985.48150803.179500.295002.812102.08860HepG2HNRNPF
SPNS1ENSG00000169682.131056.66440640.642000.7218015.1023013.63940HepG2HNRNPL
SPNS1ENSG00000169682.13958.60010615.775300.638405.858704.97820HepG2HNRNPLL
SPNS1ENSG00000169682.13769.87530427.026900.8502014.8909013.57560HepG2HNRNPU
SPNS1ENSG00000169682.131091.32200790.904900.464405.161704.20390HepG2IGF2BP1
SPNS1ENSG00000169682.131720.227501039.311900.726904.747103.88360HepG2IGF2BP2
SPNS1ENSG00000169682.13822.40100436.191700.9148014.2481012.72960HepG2ILF2
SPNS1ENSG00000169682.13517.49420351.163200.559302.745901.43570HepG2ILF3
SPNS1ENSG00000169682.131758.610101130.695400.637103.119602.23480HepG2LARP4
SPNS1ENSG00000169682.13792.58030520.199800.607403.117901.83100HepG2LIN28B
SPNS1ENSG00000169682.131973.655401135.327900.797706.410105.46210HepG2NCBP2
SPNS1ENSG00000169682.13948.60790697.373900.443802.323701.62550HepG2NOL12
SPNS1ENSG00000169682.13620.16140348.806700.830105.360203.39320HepG2NOLC1
SPNS1ENSG00000169682.131062.35300518.623901.034405.903604.26720HepG2NONO
SPNS1ENSG00000169682.13552.74020422.668100.387003.016302.13630HepG2PARN
SPNS1ENSG00000169682.13853.63200380.871701.1642014.9251013.28740HepG2PPIL4
SPNS1ENSG00000169682.13556.50650801.41390-0.526106.376505.25540HepG2PRPF4
SPNS1ENSG00000169682.131125.91100665.700400.7580010.274509.22380HepG2PUF60
SPNS1ENSG00000169682.131241.60990706.665600.8130021.3893020.05620HepG2PUM1
SPNS1ENSG00000169682.131155.84840706.152400.710804.162903.34850HepG2PUM2
SPNS1ENSG00000169682.131158.60540982.525400.237702.296901.72260HepG2PUS1
SPNS1ENSG00000169682.13880.255101159.73170-0.397803.981203.25060HepG2QKI
SPNS1ENSG00000169682.13549.99310333.270100.722603.124201.31250HepG2RBM14
SPNS1ENSG00000169682.131048.031001266.83290-0.273502.339701.54390HepG2RBM15
SPNS1ENSG00000169682.13964.09370398.753501.273604.025301.78190HepG2RBM17
SPNS1ENSG00000169682.131807.310201159.792500.639908.883908.07690HepG2RBM22
SPNS1ENSG00000169682.13831.331701052.55200-0.340402.630501.97050HepG2RBM25
SPNS1ENSG00000169682.131005.13640597.796400.749604.684003.37200HepG2RBM27
SPNS1ENSG00000169682.13787.82100485.440600.698503.593002.38400HepG2RCC2
SPNS1ENSG00000169682.13957.880301191.76250-0.315203.091702.52610HepG2NELFE
SPNS1ENSG00000169682.13630.05370361.936800.799605.754904.60000HepG2RPS3A
SPNS1ENSG00000169682.13782.96200380.279101.0418021.8367020.27360HepG2SAFB2
SPNS1ENSG00000169682.13504.04910340.818600.564502.765101.45680HepG2SART3
SPNS1ENSG00000169682.13749.08340385.011200.960102.778001.42250HepG2SF1
SPNS1ENSG00000169682.132094.248301210.479500.790807.551906.40320HepG2SF3A3
SPNS1ENSG00000169682.131030.55310638.293200.6910012.6416011.32880HepG2SLBP
SPNS1ENSG00000169682.13784.65670443.457400.8232015.4545014.12290HepG2SMN1
SPNS1ENSG00000169682.13776.52600344.490701.172504.224402.52810HepG2SNRNP200
SPNS1ENSG00000169682.13735.771101163.70750-0.6614011.6103010.78490HepG2SRSF1
SPNS1ENSG00000169682.131291.33720657.276500.9742025.1968023.58110HepG2SRSF5
SPNS1ENSG00000169682.13554.51750946.75440-0.7718014.6132013.52430HepG2SRSF9
SPNS1ENSG00000169682.13440.65200314.943700.484402.431301.40900HepG2STIP1
SPNS1ENSG00000169682.131256.46990747.509300.7491016.9817015.64880HepG2SUCLG1
SPNS1ENSG00000169682.13382.176101046.03840-1.4526037.6508035.88830HepG2TAF15
SPNS1ENSG00000169682.131004.62260600.295400.742808.429607.25810HepG2TARDBP
SPNS1ENSG00000169682.13600.29860376.390600.673302.486101.53500HepG2TFIP11
SPNS1ENSG00000169682.13729.10570961.11090-0.398602.589801.77890HepG2TIA1
SPNS1ENSG00000169682.13939.24800414.890201.1787023.2872022.10090HepG2TIAL1
SPNS1ENSG00000169682.131018.42990418.648601.2824036.1420034.39380HepG2TRIM56
SPNS1ENSG00000169682.131165.09860650.353400.841105.110403.88430HepG2TUFM
SPNS1ENSG00000169682.13802.216201094.70940-0.448503.690102.96840HepG2U2AF1
SPNS1ENSG00000169682.131200.11900688.383700.801802.705701.87800HepG2UBE2L3
SPNS1ENSG00000169682.13674.76410331.709301.024407.357906.11280HepG2UCHL5
SPNS1ENSG00000169682.131322.177501103.403900.260902.475401.47550HepG2UTP18
SPNS1ENSG00000169682.131194.341901036.430700.204501.864601.35220HepG2UTP3
SPNS1ENSG00000169682.13567.33130324.203700.807205.770804.18670HepG2XPO5
SPNS1ENSG00000169682.131888.821201180.655000.6778020.9095019.74990HepG2ZNF622
SPNS1ENSG00000169682.13889.25830636.074400.483304.832804.11760K562AGGF1
SPNS1ENSG00000169682.13967.57630698.991600.469004.444703.12880K562AKAP8
SPNS1ENSG00000169682.13994.20430661.874500.586903.640002.88760K562AKAP8L
SPNS1ENSG00000169682.131131.36060853.495900.406503.418802.03300K562APOBEC3C
SPNS1ENSG00000169682.13622.84890453.867500.456503.821602.22090K562BCCIP
SPNS1ENSG00000169682.13650.06960438.584700.567606.123304.67530K562BCLAF1
SPNS1ENSG00000169682.13700.12760533.816100.391202.481701.49480K562CCAR1
SPNS1ENSG00000169682.13989.70010760.110200.380703.661202.27730K562CCDC124
SPNS1ENSG00000169682.13399.23450282.038200.501202.959201.63140K562CIRBP
SPNS1ENSG00000169682.13445.97070332.731800.422502.750001.69680K562CSTF2
SPNS1ENSG00000169682.13981.465101189.70280-0.277602.604801.65900K562CELF1
SPNS1ENSG00000169682.13593.39460449.979800.399002.875801.81410K562DDX3X
SPNS1ENSG00000169682.13972.88340810.662400.263102.092501.45220K562EIF2S2
SPNS1ENSG00000169682.13532.02130410.377200.374402.571501.32930K562EWSR1
SPNS1ENSG00000169682.13917.57040647.844500.502104.390203.30600K562FIP1L1
SPNS1ENSG00000169682.13779.09360488.912600.672108.921407.90800K562FXR1
SPNS1ENSG00000169682.1322.82580105.58230-2.209605.374404.31430K562G3BP2
SPNS1ENSG00000169682.13542.28060405.158600.420502.556701.79200K562GPKOW
SPNS1ENSG00000169682.131442.578901080.228400.417204.003203.09690K562GRSF1
SPNS1ENSG00000169682.13716.28410532.862800.426702.507601.62360K562HNRNPM
SPNS1ENSG00000169682.13585.36240263.323501.152403.144502.02630K562IGF2BP2
SPNS1ENSG00000169682.13413.40640633.24490-0.615202.785701.36130K562ILF2
SPNS1ENSG00000169682.13631.07260438.147200.526304.028602.09600K562LSM11
SPNS1ENSG00000169682.13487.34510276.569300.817208.109206.63440K562MAGOH
SPNS1ENSG00000169682.13393.36150275.981800.511203.375302.34310K562MATR3
SPNS1ENSG00000169682.13982.11860786.845900.319702.634501.75100K562MBNL1
SPNS1ENSG00000169682.13649.86130424.518400.614202.285101.40250K562PABPN1
SPNS1ENSG00000169682.13956.39500735.433700.378902.766001.94530K562PPIG
SPNS1ENSG00000169682.13579.33980440.206900.396102.299401.48130K562PSIP1
SPNS1ENSG00000169682.13575.26200268.717301.0980015.4859013.98040K562PTBP1
SPNS1ENSG00000169682.131163.76390656.324000.826206.028905.26500K562PUS1
SPNS1ENSG00000169682.13776.22480639.550100.279302.092701.56370K562RBM15
SPNS1ENSG00000169682.13423.31340257.573100.716602.637301.81810K562RBM22
SPNS1ENSG00000169682.13448.39550251.157100.836106.920504.53870K562RBM34
SPNS1ENSG00000169682.13589.91410401.867500.553702.255101.36490K562RCC2
SPNS1ENSG00000169682.13864.91660631.346000.454002.453901.43840K562SAFB
SPNS1ENSG00000169682.13211.36730109.634400.947005.895004.61250K562SF3B4
SPNS1ENSG00000169682.13102.67940171.61160-0.741003.138601.43280K562SND1
SPNS1ENSG00000169682.13622.14370380.935300.707606.312304.59000K562SRFBP1
SPNS1ENSG00000169682.13375.60440263.452000.511602.978102.24730K562SRSF1
SPNS1ENSG00000169682.13403.71850248.858800.697905.218803.69380K562SRSF5
SPNS1ENSG00000169682.13554.29200850.01100-0.616805.677403.68530K562SSRP1
SPNS1ENSG00000169682.13571.58830777.44360-0.443803.036801.71690K562STAU1
SPNS1ENSG00000169682.13632.29380266.588701.2459016.7462014.71110K562TARDBP
SPNS1ENSG00000169682.13540.29950257.165901.0710013.3268011.41070K562TIA1
SPNS1ENSG00000169682.13461.85040252.455500.871303.952302.61220K562TRA2A
SPNS1ENSG00000169682.13725.64560450.046200.689104.649303.34920K562TRIM56
SPNS1ENSG00000169682.1352.06060105.57750-1.020003.271802.40010K562U2AF2
SPNS1ENSG00000169682.131319.047501022.175800.367804.836203.91450K562UPF1
SPNS1ENSG00000169682.13640.67000874.64570-0.449104.041302.97740K562WDR3
SPNS1ENSG00000169682.13738.03910909.51510-0.301403.041002.15530K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPNS1 is not available on ENCORE database.





14 RBPs can affect the splicing of SPNS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.198000.000000.00000excludedHepG2RBM22
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.265000.000000.00000excludedHepG2U2AF1
SESPNS1ENSG00000169682.13chr16+2899322128993377289927902899293628993676289938660.059000.003210.06830includedHepG2HNRNPK
SESPNS1ENSG00000169682.13chr16+289932212899337728992775289929362899367628993866-0.479000.000000.00000excludedHepG2U2AF2
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.141000.000290.00430excludedK562AQR
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.123000.000020.00068excludedK562PUS1
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.159000.000110.01288excludedHepG2IGF2BP3
SESPNS1ENSG00000169682.13chr16+289951062899527828994427289946112899552528995869-0.144000.000060.00470excludedHepG2PCBP1
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.102000.000440.01824excludedK562UTP18
SESPNS1ENSG00000169682.13chr16+289932212899337728992775289929362899367628993866-0.159000.000020.00146excludedK562HNRNPU
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.097000.000870.02464excludedK562RBM15
SESPNS1ENSG00000169682.13chr16+289951062899527828994512289946112899552528995864-0.128000.001200.06943excludedHepG2SRSF9
SESPNS1ENSG00000169682.13chr16+289932212899337728992790289929362899367628993866-0.189000.000000.00002excludedK562HNRNPC
RISPNS1ENSG00000169682.13chr16+2899058028990792289905802899062728990725289907920.065000.004080.04437includedK562UTP18
MXESPNS1ENSG00000169682.13chr16+28993221289933772899367628993866289927902899293628994177289942430.082000.002780.047901includedHepG2FTO
MXESPNS1ENSG00000169682.13chr16+2899322128993377289936762899378228992790289929362899417728994243-0.199000.000020.000342includedK562AQR
MXESPNS1ENSG00000169682.13chr16+2899322128993377289936762899386628992790289929362899417728994243-0.135000.007340.049292includedK562AQR
MXESPNS1ENSG00000169682.13chr16+2899322128993377289936762899386628992790289929362899417728994243-0.091000.000570.005082includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPNS1 is not avaliable on ENCORE database.