SIPA1

General Information

Gene Name       : SIPA1
Gene ID             : ENSG00000213445.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SIPA1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIPA1ENSG00000213445.93.0710.886.98ENCSR000AEF
HepG2SIPA1ENSG00000213445.98.863.866.36ENCSR985KAT
K562SIPA1ENSG00000213445.921.6610.4516.05ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIPA1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIPA1 RNA is bound by 9 proteins.  







eCLIP assay for SIPA1 is not avaliable on ENCORE database.





9 proteins are bound to SIPA1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116540827065408354+3'-UTR,5'-UTR,intron-Proximal5.067218.03975K562BUD13
chr116540837565408458+3'-UTR,5'-UTR,CDS4.571164.15208K562RBM15
chr116540827065408323+3'-UTR,5'-UTR,intron-Proximal3.912383.48187K562RBM15
chr116541829665418376+3'-UTR8.2564129.20897K562PUM2
chr116540565365405698+5'-UTR,intron-Proximal3.533644.88100K562AQR
chr116540567765405734+5'-UTR,intron-Proximal3.601914.44431K562BUD13
chr116541745465417521+CDS4.073673.20743HepG2PPIG
chr116540973165409783+CDS3.831783.01428K562UCHL5
chr116541375265413833+CDS4.629444.32860K562METAP2
chr116541480165414873+CDS,intron-Proximal3.383787.00923K562SF3B4
chr116540993265409967+CDS,intron-Proximal3.182693.06971K562YBX3
chr116540845865408505+CDS3.406284.38249K562RBM15
chr116541259865412644+CDS,intron-Proximal5.027315.69951K562AQR
chr116540876965408832+CDS4.547763.81597K562RBM15
chr116541456665414638+intron-Distal,intron-Proximal3.669675.24705K562BUD13
chr116541798465418036+intron-Proximal5.162135.13952K562SF3B4
chr116541327965413320+intron-Proximal4.560864.09264K562AQR
chr116541513765415203+intron-Proximal5.181376.22530K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIPA1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIPA1 is not available on ENCORE database.

  • 104 RBPs can affect the levels of SIPA1.  








The Knockdown/knockout RNA-Seq assay for SIPA1 is not available on ENCORE database.





104 RBPs can affect the gene expression of SIPA1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIPA1ENSG00000213445.4470.99390207.390801.1833017.8447016.58650HepG2ACO1
SIPA1ENSG00000213445.441.1506095.86000-1.220004.227803.02290HepG2ADAR
SIPA1ENSG00000213445.4356.47410109.805701.698708.958008.06140HepG2AKAP1
SIPA1ENSG00000213445.4270.11640165.731700.704603.459402.30210HepG2AKAP8
SIPA1ENSG00000213445.4335.30170208.374500.686205.381104.34550HepG2AKAP8L
SIPA1ENSG00000213445.4186.0591090.833201.034402.709901.93300HepG2ASCC1
SIPA1ENSG00000213445.4213.2318096.782901.139504.435003.24740HepG2BCCIP
SIPA1ENSG00000213445.4123.12210190.80770-0.632002.492401.92110HepG2BOP1
SIPA1ENSG00000213445.4152.67190207.35690-0.441701.959301.38720HepG2CKAP4
SIPA1ENSG00000213445.4320.05620201.229200.669403.905102.59820HepG2CPSF7
SIPA1ENSG00000213445.4307.41240125.497401.2924013.7906012.57010HepG2CELF1
SIPA1ENSG00000213445.447.0920086.49210-0.877102.339901.70910HepG2DDX21
SIPA1ENSG00000213445.429.0951084.73930-1.542305.234803.97140HepG2DDX24
SIPA1ENSG00000213445.4265.72080105.138801.337505.646404.78260HepG2DDX3X
SIPA1ENSG00000213445.4171.26970105.782100.695102.729301.38410HepG2DDX52
SIPA1ENSG00000213445.4272.4024095.173701.517008.619807.33650HepG2DDX55
SIPA1ENSG00000213445.4104.70630167.88810-0.681202.666101.67080HepG2DDX5
SIPA1ENSG00000213445.4532.0797090.426602.5567010.170809.06790HepG2DDX6
SIPA1ENSG00000213445.452.2292093.09780-0.833902.402801.48860HepG2DHX30
SIPA1ENSG00000213445.476.33370198.41970-1.378209.920008.79940HepG2DKC1
SIPA1ENSG00000213445.4190.2924096.522000.979205.894904.90150HepG2DNAJC21
SIPA1ENSG00000213445.4172.9543095.679800.854004.893804.06600HepG2DNAJC2
SIPA1ENSG00000213445.4194.3068086.819901.162103.526302.86120HepG2EIF2S1
SIPA1ENSG00000213445.4113.77940211.67580-0.895604.692803.31030HepG2ESF1
SIPA1ENSG00000213445.4506.56310246.749701.037607.016505.84910HepG2FIP1L1
SIPA1ENSG00000213445.481.88420175.46860-1.099603.006101.94580HepG2FTO
SIPA1ENSG00000213445.4335.8061096.912401.7928015.2320013.74740HepG2FXR1
SIPA1ENSG00000213445.4200.7080089.816201.160003.715402.94780HepG2G3BP1
SIPA1ENSG00000213445.4161.6519088.159600.874602.909601.86390HepG2GNB2L1
SIPA1ENSG00000213445.4287.64830198.005600.538703.489102.40190HepG2HDGF
SIPA1ENSG00000213445.443.3418097.44680-1.168903.495402.77960HepG2HNRNPA1
SIPA1ENSG00000213445.4225.5588091.143701.307203.790802.98380HepG2HNRNPK
SIPA1ENSG00000213445.4188.16380122.889200.614503.137902.42280HepG2HNRNPL
SIPA1ENSG00000213445.4119.72280189.51110-0.662602.491701.88990HepG2HNRNPLL
SIPA1ENSG00000213445.4132.24020187.15180-0.501001.979501.35940HepG2IGF2BP1
SIPA1ENSG00000213445.4153.49510109.989000.480701.954501.32520HepG2ILF2
SIPA1ENSG00000213445.4181.1993086.423901.068004.924903.41330HepG2LARP7
SIPA1ENSG00000213445.4275.8502097.463501.500906.434305.50470HepG2MATR3
SIPA1ENSG00000213445.4308.34780133.782501.204605.689204.60350HepG2NOL12
SIPA1ENSG00000213445.4253.1430087.474801.532906.995205.23970HepG2NONO
SIPA1ENSG00000213445.492.07210168.03140-0.867903.302702.48530HepG2NSUN2
SIPA1ENSG00000213445.4175.06780106.578600.715903.375402.44860HepG2PARN
SIPA1ENSG00000213445.4149.5126087.289500.776303.301202.65040HepG2PCBP1
SIPA1ENSG00000213445.487.88030150.03980-0.771703.502702.64290HepG2PRPF4
SIPA1ENSG00000213445.4288.7535088.816501.7008017.9913016.82570HepG2PTBP1
SIPA1ENSG00000213445.4331.24010135.582701.2886016.3975015.20070HepG2PUM1
SIPA1ENSG00000213445.4241.65920135.478500.834805.232604.32380HepG2PUM2
SIPA1ENSG00000213445.4437.88720258.158900.762206.732505.47080HepG2RBM15
SIPA1ENSG00000213445.4184.86920104.222600.826702.673001.69690HepG2RBM27
SIPA1ENSG00000213445.4263.1835098.847401.4127011.7926010.82500HepG2NELFE
SIPA1ENSG00000213445.4176.8787092.057100.942104.720803.94460HepG2RECQL
SIPA1ENSG00000213445.4160.8561099.659600.690602.477001.89190HepG2RPS19
SIPA1ENSG00000213445.4160.7624096.104500.742202.216801.49650HepG2RPS2
SIPA1ENSG00000213445.4210.4282098.119401.100605.265903.77190HepG2RPS5
SIPA1ENSG00000213445.4181.0784095.890100.917105.291004.45280HepG2SAFB2
SIPA1ENSG00000213445.4245.75540145.223400.758803.695902.91290HepG2SF3A3
SIPA1ENSG00000213445.480.32800187.58370-1.223606.569205.52030HepG2SF3B1
SIPA1ENSG00000213445.4240.8370092.476301.3808010.910809.85570HepG2SF3B4
SIPA1ENSG00000213445.4182.9401075.372701.279202.962501.45200HepG2SFPQ
SIPA1ENSG00000213445.4216.45220111.820700.952806.530005.60800HepG2SMN1
SIPA1ENSG00000213445.4213.1822076.689001.474903.155002.12430HepG2SMNDC1
SIPA1ENSG00000213445.4175.3357069.417001.336703.605402.06400HepG2SNRNP200
SIPA1ENSG00000213445.472.54040208.71800-1.524707.859806.53890HepG2SNRNP70
SIPA1ENSG00000213445.4248.79200126.109300.980207.510606.54750HepG2SRSF5
SIPA1ENSG00000213445.4126.1515078.523700.683902.491901.96200HepG2SRSF9
SIPA1ENSG00000213445.442.14160249.14090-2.5636030.6201029.33200HepG2SSB
SIPA1ENSG00000213445.4146.2256081.583100.841802.447201.42120HepG2STIP1
SIPA1ENSG00000213445.4569.28520143.412401.9889046.3763044.38140HepG2SUCLG1
SIPA1ENSG00000213445.4231.4438094.719001.288805.683504.76790HepG2SUPV3L1
SIPA1ENSG00000213445.446.9169086.75030-0.886802.429101.89880HepG2TAF15
SIPA1ENSG00000213445.4188.77370105.565400.838404.852404.14870HepG2TRIM56
SIPA1ENSG00000213445.4205.83440124.785100.721902.837801.95350HepG2TUFM
SIPA1ENSG00000213445.4403.5539080.715202.3217010.043708.04410HepG2U2AF2
SIPA1ENSG00000213445.4371.66320132.092001.492403.932802.92590HepG2UBE2L3
SIPA1ENSG00000213445.4134.6689055.936401.267505.296504.24090HepG2UCHL5
SIPA1ENSG00000213445.4243.12720124.343000.967303.258302.61780HepG2UTP3
SIPA1ENSG00000213445.490.10640148.07060-0.716603.024502.32830HepG2ZC3H8
SIPA1ENSG00000213445.4254.08400141.645600.842906.143005.41160HepG2ZNF622
SIPA1ENSG00000213445.4908.77600666.352500.447505.118404.38550K562AGGF1
SIPA1ENSG00000213445.41011.69570693.369500.545001.970401.41680K562AKAP8L
SIPA1ENSG00000213445.4790.413901161.25990-0.555004.940604.19710K562AQR
SIPA1ENSG00000213445.4782.42740481.829600.699306.168404.71320K562BCLAF1
SIPA1ENSG00000213445.4984.11900796.329300.305402.381501.30180K562CCDC124
SIPA1ENSG00000213445.4472.02570301.237500.647904.091102.51950K562CIRBP
SIPA1ENSG00000213445.41371.684101778.71160-0.374904.219903.00740K562CELF1
SIPA1ENSG00000213445.41215.73030885.155500.457705.848404.03990K562DDX21
SIPA1ENSG00000213445.4291.38050177.375500.716004.500803.49620K562EIF3G
SIPA1ENSG00000213445.4887.89070645.683700.459503.761802.76230K562FIP1L1
SIPA1ENSG00000213445.418.36920111.84940-2.6062012.8091011.05140K562G3BP2
SIPA1ENSG00000213445.4618.16370472.349500.388002.398301.65630K562GPKOW
SIPA1ENSG00000213445.4658.52730281.079901.228204.018402.68630K562IGF2BP2
SIPA1ENSG00000213445.4284.67760403.31710-0.502602.162401.34840K562KRR1
SIPA1ENSG00000213445.4467.18190295.391000.661305.641204.43010K562MAGOH
SIPA1ENSG00000213445.4492.85690294.789800.741404.862803.60200K562MATR3
SIPA1ENSG00000213445.4801.016001089.25670-0.443405.683504.55130K562MTPAP
SIPA1ENSG00000213445.41418.766801210.245400.229202.694601.95720K562NSUN2
SIPA1ENSG00000213445.4941.94300733.009400.361702.586301.79740K562PPIG
SIPA1ENSG00000213445.4600.30650286.991801.0646015.0787013.59490K562PTBP1
SIPA1ENSG00000213445.41058.688301678.82600-0.6652010.874708.68200K562PUM1
SIPA1ENSG00000213445.4918.91770669.994600.455704.724903.96950K562RBM15
SIPA1ENSG00000213445.4407.41630275.183800.566002.624101.80700K562RBM22
SIPA1ENSG00000213445.4468.26080268.257100.803606.598204.25980K562RBM34
SIPA1ENSG00000213445.4457.55190262.876900.799405.252803.81180K562RPS3
SIPA1ENSG00000213445.4962.96400719.373400.420602.660301.60130K562SAFB
SIPA1ENSG00000213445.4230.52270116.232500.987807.044805.64240K562SF3B4
SIPA1ENSG00000213445.4591.21930281.349101.071207.593806.43040K562SRSF1
SIPA1ENSG00000213445.4471.67980253.741900.894307.866405.96200K562SRSF4
SIPA1ENSG00000213445.4433.55870265.716600.706205.480503.91280K562SRSF5
SIPA1ENSG00000213445.4672.60520385.666600.802302.426401.47900K562SUPV3L1
SIPA1ENSG00000213445.447.54680109.78740-1.207303.816201.98680K562TAF15
SIPA1ENSG00000213445.4772.25220284.740501.439308.286906.97650K562TARDBP
SIPA1ENSG00000213445.4612.83660274.665201.1577016.4532014.33500K562TIA1
SIPA1ENSG00000213445.4550.58830269.535701.0304011.411208.78330K562TRA2A
SIPA1ENSG00000213445.41798.665901385.485100.376405.805403.93720K562TROVE2
SIPA1ENSG00000213445.4669.23210408.358600.712602.492401.53030K562UCHL5
SIPA1ENSG00000213445.41082.932501283.25010-0.244902.432801.75820K562UPF1
SIPA1ENSG00000213445.4898.789401141.84320-0.345304.347003.30460K562WDR43
SIPA1ENSG00000213445.4736.54840416.104000.823703.627702.17770K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIPA1 is not available on ENCORE database.





1 RBPs can affect the splicing of SIPA1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESIPA1ENSG00000213445.4chr11+6540660665406722654056066540565365408301654087000.241000.000480.07494includedK562UPF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SIPA1 is not avaliable on ENCORE database.