SH2D4A

General Information

Gene Name       : SH2D4A
Gene ID             : ENSG00000104611.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SH2D4A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SH2D4AENSG00000104611.110.000.080.04ENCSR000AEF
HepG2SH2D4AENSG00000104611.117.7014.8511.28ENCSR985KAT
K562SH2D4AENSG00000104611.110.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SH2D4A is not avaliable on ENCORE database.



Proteins bound to RNA
  • SH2D4A RNA is bound by 5 proteins.  







eCLIP assay for SH2D4A is not avaliable on ENCORE database.





5 proteins are bound to SH2D4A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr81917136619171529+5'-UTR,intron-Distal,intron-Proximal4.665536.37401HepG2RBFOX2
chr81921877219218842+CDS,intron-Proximal4.872825.68196HepG2BCLAF1
chr81921986319219943+intron-Distal3.862743.10834HepG2CSTF2
chr81922133219221416+intron-Distal3.314455.79202HepG2U2AF2
chr81922151219221582+intron-Proximal4.110003.56713HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SH2D4A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SH2D4A is not available on ENCORE database.

  • 94 RBPs can affect the levels of SH2D4A.  








The Knockdown/knockout RNA-Seq assay for SH2D4A is not available on ENCORE database.





94 RBPs can affect the gene expression of SH2D4A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SH2D4AENSG00000104611.7344.36070587.41650-0.770505.212403.96090HepG2ABCF1
SH2D4AENSG00000104611.7551.38510264.073101.0620010.554509.09180HepG2ASCC1
SH2D4AENSG00000104611.7303.44770604.27450-0.9938015.0930013.71580HepG2AUH
SH2D4AENSG00000104611.7244.00940334.70920-0.456002.222501.38650HepG2BCCIP
SH2D4AENSG00000104611.7117.17650475.76250-2.0216023.8997022.41720HepG2BOP1
SH2D4AENSG00000104611.7368.49770629.57410-0.772706.942905.79260HepG2CALR
SH2D4AENSG00000104611.7404.47820978.81270-1.2750015.1947013.06400HepG2CCAR1
SH2D4AENSG00000104611.7480.86120385.868300.317402.190901.58820HepG2CKAP4
SH2D4AENSG00000104611.7142.18140269.26460-0.921304.288503.33050HepG2CNOT7
SH2D4AENSG00000104611.7451.96910627.93270-0.474404.761903.82940HepG2DAZAP1
SH2D4AENSG00000104611.7255.97550356.94350-0.479703.667902.72640HepG2DDX19B
SH2D4AENSG00000104611.7220.28940398.85670-0.856507.100406.06540HepG2DDX21
SH2D4AENSG00000104611.7199.54680390.13970-0.967308.980807.36380HepG2DDX24
SH2D4AENSG00000104611.7185.36540307.87420-0.732003.801102.32220HepG2DDX27
SH2D4AENSG00000104611.7207.92870305.72020-0.556102.574201.96870HepG2DDX3X
SH2D4AENSG00000104611.7179.24560329.11540-0.876705.546704.49720HepG2DDX55
SH2D4AENSG00000104611.7243.71010513.79050-1.076006.709605.19210HepG2DDX5
SH2D4AENSG00000104611.7216.38360411.79360-0.928308.366406.75740HepG2DHX30
SH2D4AENSG00000104611.7166.44480369.24120-1.1495012.5911011.36150HepG2DKC1
SH2D4AENSG00000104611.7143.69230426.93710-1.5710023.2117021.39180HepG2DNAJC21
SH2D4AENSG00000104611.7323.25870443.61470-0.456602.270701.43400HepG2EEF2
SH2D4AENSG00000104611.7152.09590252.46210-0.731103.494702.83290HepG2EIF2S1
SH2D4AENSG00000104611.7229.78670376.54090-0.712505.517304.06410HepG2EIF3G
SH2D4AENSG00000104611.7546.61970271.657901.008607.313806.22500HepG2EIF4B
SH2D4AENSG00000104611.7380.75920619.59770-0.702507.982306.69860HepG2EIF4G1
SH2D4AENSG00000104611.7275.97060593.51630-1.1048012.5049010.85680HepG2EIF4G2
SH2D4AENSG00000104611.7415.42560593.19310-0.513902.444401.71700HepG2FIP1L1
SH2D4AENSG00000104611.7188.00770273.90700-0.542902.809401.53000HepG2FKBP4
SH2D4AENSG00000104611.7274.02570178.929400.614803.150602.31560HepG2FUBP3
SH2D4AENSG00000104611.7467.45000281.525300.731405.161104.23620HepG2FXR1
SH2D4AENSG00000104611.7168.65360320.62290-0.926806.311704.96210HepG2GEMIN5
SH2D4AENSG00000104611.7201.29370408.77930-1.022008.786706.95420HepG2GNB2L1
SH2D4AENSG00000104611.7188.51620495.05240-1.3929014.5326013.17880HepG2GPKOW
SH2D4AENSG00000104611.7408.65620249.249400.713203.786102.48110HepG2GRSF1
SH2D4AENSG00000104611.7287.13950368.46860-0.359802.178501.30380HepG2HDGF
SH2D4AENSG00000104611.7233.77660431.02790-0.882707.339706.36220HepG2HNRNPA1
SH2D4AENSG00000104611.7203.31820479.45740-1.2377013.2798011.86530HepG2HNRNPC
SH2D4AENSG00000104611.7115.64260233.23190-1.012105.655703.51500HepG2HNRNPD
SH2D4AENSG00000104611.7335.13700442.16130-0.399802.657701.95350HepG2HNRNPF
SH2D4AENSG00000104611.7477.87040264.471000.853406.958005.88630HepG2HNRNPK
SH2D4AENSG00000104611.7681.21900571.962100.252101.984601.40200HepG2HNRNPL
SH2D4AENSG00000104611.7328.40010476.28610-0.536404.849504.06510HepG2HNRNPU
SH2D4AENSG00000104611.7288.30540435.40420-0.594804.432603.53430HepG2IGF2BP1
SH2D4AENSG00000104611.7136.46830265.43150-0.959805.725204.78800HepG2IGF2BP2
SH2D4AENSG00000104611.7128.17630262.49250-1.034105.729703.77010HepG2ILF3
SH2D4AENSG00000104611.7414.485701033.33470-1.3179016.6280014.62400HepG2LARP4
SH2D4AENSG00000104611.7308.20220420.47940-0.448202.612901.43840HepG2LIN28B
SH2D4AENSG00000104611.7174.52100480.28260-1.4605016.3299014.55450HepG2MSI2
SH2D4AENSG00000104611.7369.69530622.66320-0.752108.347407.04560HepG2NOL12
SH2D4AENSG00000104611.7211.71690418.94460-0.984607.919306.69920HepG2NSUN2
SH2D4AENSG00000104611.777.97490246.08900-1.6581010.394908.64280HepG2PABPC1
SH2D4AENSG00000104611.7499.43170266.275200.9073011.5937010.48860HepG2PCBP1
SH2D4AENSG00000104611.7219.59300531.95820-1.2765010.849408.63300HepG2PRPF6
SH2D4AENSG00000104611.7133.53300253.74240-0.926205.575904.47220HepG2PRPF8
SH2D4AENSG00000104611.7369.92440270.954700.449102.633502.09760HepG2PTBP1
SH2D4AENSG00000104611.7247.37060594.41980-1.2648016.8894015.58750HepG2PUF60
SH2D4AENSG00000104611.7852.78950631.041900.434406.095605.28640HepG2PUM1
SH2D4AENSG00000104611.7409.16020630.55670-0.624005.645404.70010HepG2PUM2
SH2D4AENSG00000104611.7149.24320293.42990-0.975407.264606.32380HepG2QKI
SH2D4AENSG00000104611.7404.56230585.95300-0.534404.346203.30130HepG2RBM15
SH2D4AENSG00000104611.7155.31920579.86150-1.9005037.1309035.65590HepG2RBM22
SH2D4AENSG00000104611.7194.45120301.53850-0.632903.765003.15260HepG2NELFE
SH2D4AENSG00000104611.7437.90290280.856700.640705.508304.67500HepG2RECQL
SH2D4AENSG00000104611.7214.55270476.29310-1.1505012.5364011.26820HepG2RPLP0
SH2D4AENSG00000104611.7314.44670479.63700-0.609103.039802.05170HepG2RPS10
SH2D4AENSG00000104611.7176.09620350.41050-0.992708.583507.57290HepG2RPS19
SH2D4AENSG00000104611.7266.14200445.44340-0.743005.688204.56550HepG2RPS2
SH2D4AENSG00000104611.7161.03160270.32460-0.747303.578402.66770HepG2RPS3A
SH2D4AENSG00000104611.7335.03360454.72320-0.440702.494601.47560HepG2RPS5
SH2D4AENSG00000104611.7370.23150250.989600.560702.258201.54080HepG2RRP9
SH2D4AENSG00000104611.7211.27110424.14290-1.0055012.3812011.16620HepG2SAFB2
SH2D4AENSG00000104611.7222.69790351.67090-0.659103.803302.69860HepG2SERBP1
SH2D4AENSG00000104611.7317.61630459.24790-0.532002.766302.09220HepG2SF3A3
SH2D4AENSG00000104611.7255.64690654.94210-1.3572027.1186025.96990HepG2SRFBP1
SH2D4AENSG00000104611.7352.99010503.21370-0.511502.466301.52710HepG2SRSF3
SH2D4AENSG00000104611.7306.54610434.40360-0.502903.753702.96120HepG2SRSF7
SH2D4AENSG00000104611.7367.88720239.547900.618805.220704.50490HepG2SRSF9
SH2D4AENSG00000104611.7277.32110568.66210-1.0360015.9417014.91900HepG2SSB
SH2D4AENSG00000104611.7517.68370297.622800.798506.142704.32860HepG2SSRP1
SH2D4AENSG00000104611.7189.47500396.38830-1.064906.807904.97810HepG2STAU1
SH2D4AENSG00000104611.7525.98640667.48350-0.343701.851901.32440HepG2SUCLG1
SH2D4AENSG00000104611.7147.57440327.58770-1.150408.421207.34760HepG2SUPV3L1
SH2D4AENSG00000104611.7181.36940264.67300-0.545302.858302.28900HepG2TAF15
SH2D4AENSG00000104611.7317.84860460.61050-0.535203.383202.59100HepG2TARDBP
SH2D4AENSG00000104611.7154.62090462.73130-1.5814023.2780022.09240HepG2TIAL1
SH2D4AENSG00000104611.7371.63410466.94250-0.329402.167601.65620HepG2TRIM56
SH2D4AENSG00000104611.7262.74500614.79540-1.2264011.659309.89890HepG2UBE2L3
SH2D4AENSG00000104611.7258.10430407.28320-0.658105.980105.01630HepG2UPF1
SH2D4AENSG00000104611.7157.17010299.86030-0.932005.242803.83680HepG2UPF2
SH2D4AENSG00000104611.7250.16670393.21520-0.652405.337204.55060HepG2UTP3
SH2D4AENSG00000104611.7113.25780242.12720-1.096206.438304.76860HepG2XPO5
SH2D4AENSG00000104611.7380.06960537.02150-0.498702.452701.45610HepG2XRCC6
SH2D4AENSG00000104611.7184.02440474.01420-1.3650022.4017020.82250HepG2ZC3H8
SH2D4AENSG00000104611.7214.28470447.93290-1.0638015.2253014.19920HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SH2D4A is not available on ENCORE database.





4 RBPs can affect the splicing of SH2D4A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESH2D4AENSG00000104611.7chr8+192147131921479419192196191923681921871319218825-0.221000.004540.04912excludedHepG2U2AF2
SESH2D4AENSG00000104611.7chr8+1921471319214794191921961919236819218713192188250.365000.000130.03964includedHepG2EFTUD2
SESH2D4AENSG00000104611.7chr8+1921471319214794191921961919236819218713192188250.396000.001540.03618includedHepG2SRSF1
SESH2D4AENSG00000104611.7chr8+1921471319214794191921961919236819218713192188250.374000.000090.02919includedHepG2EIF3D

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SH2D4A is not avaliable on ENCORE database.