SAP130

General Information

Gene Name       : SAP130
Gene ID             : ENSG00000136715.18
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SAP130)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SAP130ENSG00000136715.1810.5813.9612.27ENCSR000AEF
HepG2SAP130ENSG00000136715.1828.7322.9125.82ENCSR985KAT
K562SAP130ENSG00000136715.1820.2222.1221.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SAP130 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SAP130 RNA is bound by 24 proteins.  







eCLIP assay for SAP130 is not avaliable on ENCORE database.





24 proteins are bound to SAP130 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2128699054128699153-3'-UTR,intron-Distal3.012756.83987K562YBX3
chr2128699413128699518-3'-UTR,intron-Distal5.5569110.53672K562FAM120A
chr2128698941128699011-3'-UTR,intron-Distal3.304175.38711K562YBX3
chr2128698814128698891-3'-UTR,intron-Distal5.343839.81639K562PUM2
chr2128784773128784858-5'-UTR,intron-Distal4.636175.63094K562GTF2F1
chr2128785528128785645-5'-UTR,intron-Distal,intron-Proximal3.180204.39129HepG2NCBP2
chr2128784762128784889-5'-UTR,intron-Distal,intron-Proximal3.083186.98206HepG2PRPF4
chr2128754020128754064-CDS,intron-Distal3.068093.10464K562IGF2BP2
chr2128767854128767968-CDS,intron-Distal,intron-Proximal3.153045.34387HepG2IGF2BP1
chr2128775212128775283-CDS,intron-Distal,intron-Proximal3.940996.04280HepG2PRPF8
chr2128750780128750836-CDS,intron-Distal4.759197.34329K562IGF2BP2
chr2128772376128772428-CDS,intron-Distal,intron-Proximal3.149355.39278K562ZNF622
chr2128770700128770728-CDS,intron-Distal3.976003.98716K562IGF2BP1
chr2128753933128754010-CDS,intron-Distal3.450694.41952K562IGF2BP1
chr2128699961128700005-CDS,intron-Distal,intron-Proximal4.752464.02817HepG2PRPF8
chr2128703099128703146-CDS,intron-Distal,intron-Proximal3.588803.55754HepG2U2AF2
chr2128753933128754020-CDS,intron-Distal4.035517.01305K562IGF2BP2
chr2128712620128712697-CDS,intron-Distal4.810804.77733K562IGF2BP2
chr2128750773128750836-CDS,intron-Distal5.182496.93935HepG2IGF2BP1
chr2128767892128767967-CDS,intron-Distal,intron-Proximal3.919437.48557K562IGF2BP1
chr2128767932128767992-CDS,intron-Distal,intron-Proximal3.360595.11990K562AQR
chr2128753928128753986-CDS,intron-Distal3.650163.15019HepG2IGF2BP1
chr2128712750128712807-CDS,intron-Distal4.082383.51789K562IGF2BP2
chr2128744508128744562-CDS,intron-Distal,intron-Proximal3.616373.95921HepG2U2AF2
chr2128757945128758024-CDS,intron-Distal3.990517.49884K562YBX3
chr2128750774128750848-CDS,intron-Distal3.670505.48238K562IGF2BP1
chr2128783787128783852-CDS,intron-Distal3.313853.69775K562YBX3
chr2128774068128774147-CDS,intron-Distal,intron-Proximal3.453704.28285K562AQR
chr2128712733128712813-CDS,intron-Distal4.645245.59872HepG2IGF2BP1
chr2128770529128770607-CDS,intron-Distal,intron-Proximal3.407154.28285K562AQR
chr2128757884128757926-CDS,intron-Distal3.943053.31982HepG2IGF2BP1
chr2128747378128747431-CDS,intron-Distal4.236274.61859K562IGF2BP1
chr2128712668128712733-CDS,intron-Distal4.104016.59648HepG2IGF2BP1
chr2128747102128747164-CDS,intron-Distal,intron-Proximal5.400198.38577HepG2PRPF8
chr2128747251128747301-CDS,intron-Distal3.718564.79276K562ZNF622
chr2128770559128770611-CDS,intron-Distal,intron-Proximal4.133027.08947HepG2PRPF8
chr2128774172128774244-intron-Distal,intron-Proximal3.827803.45805K562KHSRP
chr2128785378128785465-intron-Distal4.016307.10319HepG2CSTF2T
chr2128785225128785308-intron-Distal4.709183.13028HepG2FAM120A
chr2128738620128738709-intron-Distal4.037123.30705HepG2GTF2F1
chr2128738416128738500-intron-Distal4.251136.40934HepG2HNRNPM
chr2128762181128762263-intron-Distal4.333804.05848HepG2QKI
chr2128738649128738718-intron-Distal4.606894.46189K562GTF2F1
chr2128785370128785470-intron-Distal4.756674.46189K562GTF2F1
chr2128785161128785204-intron-Distal3.808133.43867K562CSTF2T
chr2128785376128785467-intron-Distal4.220395.16644HepG2FAM120A
chr2128705289128705442-intron-Distal3.109904.66424HepG2HNRNPL
chr2128784403128784457-intron-Distal4.922713.62726K562DROSHA
chr2128704529128704634-intron-Distal5.9138212.52551K562PTBP1
chr2128785353128785458-intron-Distal4.603955.27179K562EWSR1
chr2128758981128759035-intron-Distal5.5368012.16319HepG2QKI
chr2128785370128785417-intron-Distal3.363163.94360HepG2GTF2F1
chr2128738823128738898-intron-Distal5.4401710.32927K562GTF2F1
chr2128738836128738907-intron-Distal4.519414.79286HepG2PRPF4
chr2128759035128759070-intron-Distal4.182273.16986HepG2QKI
chr2128780899128781023-intron-Distal3.939887.26542HepG2ILF3
chr2128750957128751016-intron-Distal,intron-Proximal4.587524.08582K562SMNDC1
chr2128738822128738897-intron-Distal4.105604.48935K562CSTF2T
chr2128774250128774353-intron-Distal4.223783.48768HepG2KHSRP
chr2128784413128784491-intron-Distal3.797745.34741HepG2NKRF
chr2128738836128738911-intron-Distal5.2971013.48337HepG2FAM120A
chr2128784391128784515-intron-Distal5.196629.54146K562CSTF2T
chr2128784590128784643-intron-Distal3.247833.72734HepG2CSTF2T
chr2128739336128739383-intron-Distal4.814183.41584HepG2FAM120A
chr2128785373128785481-intron-Distal5.071067.90577HepG2PRPF4
chr2128738819128738902-intron-Distal4.831416.40009HepG2GTF2F1
chr2128704541128704625-intron-Distal4.4913814.63885HepG2PTBP1
chr2128784393128784494-intron-Distal3.071603.20905HepG2DROSHA
chr2128738828128738893-intron-Distal3.548855.16304HepG2CSTF2T
chr2128785386128785470-intron-Distal5.3319314.49820HepG2EFTUD2
chr2128785372128785427-intron-Distal4.183343.70058K562CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SAP130 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SAP130 is not available on ENCORE database.

  • 84 RBPs can affect the levels of SAP130.  








The Knockdown/knockout RNA-Seq assay for SAP130 is not available on ENCORE database.





84 RBPs can affect the gene expression of SAP130 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SAP130ENSG00000136715.13745.762801210.75300-0.699106.098205.34350HepG2AKAP1
SAP130ENSG00000136715.131355.320501713.80320-0.338604.439203.60570HepG2AUH
SAP130ENSG00000136715.13580.95460938.83380-0.692405.833404.58090HepG2BCLAF1
SAP130ENSG00000136715.131250.352302334.21620-0.900608.783907.78960HepG2BOP1
SAP130ENSG00000136715.131044.984801621.73150-0.6341010.002208.67220HepG2CALR
SAP130ENSG00000136715.131382.335802143.00250-0.632503.673802.89240HepG2CPSF6
SAP130ENSG00000136715.131154.930401589.88670-0.461106.680605.76500HepG2CELF1
SAP130ENSG00000136715.131395.446701709.34840-0.292704.071803.20030HepG2DAZAP1
SAP130ENSG00000136715.131120.06520965.116100.214702.043001.31700HepG2DDX19B
SAP130ENSG00000136715.13795.388501087.52670-0.451305.108303.56910HepG2DDX1
SAP130ENSG00000136715.13924.833901159.80540-0.326601.935501.40340HepG2DDX3X
SAP130ENSG00000136715.13682.116901062.31450-0.639105.119904.10800HepG2DDX55
SAP130ENSG00000136715.131472.469302433.51530-0.724804.513403.27450HepG2DDX59
SAP130ENSG00000136715.131162.084701685.48720-0.536505.005503.67590HepG2DDX5
SAP130ENSG00000136715.13691.90820996.30710-0.526003.648102.94700HepG2DDX6
SAP130ENSG00000136715.13749.501801028.52760-0.456604.063102.89010HepG2DHX30
SAP130ENSG00000136715.13708.90870988.86630-0.480203.015801.85220HepG2AGO1
SAP130ENSG00000136715.13651.99500957.76400-0.554804.374903.63920HepG2EIF2S1
SAP130ENSG00000136715.13816.006101149.08160-0.493803.690501.65190HepG2EIF3H
SAP130ENSG00000136715.131152.782301686.52370-0.548909.973208.57730HepG2EIF4G1
SAP130ENSG00000136715.131171.025701615.55550-0.464304.266703.26960HepG2EIF4G2
SAP130ENSG00000136715.131213.455301967.70870-0.6974017.2708015.97910HepG2ETF1
SAP130ENSG00000136715.131331.135301067.933300.317701.978901.38980HepG2FXR1
SAP130ENSG00000136715.131036.01280791.805400.387702.684301.80080HepG2GEMIN5
SAP130ENSG00000136715.131650.964302429.43800-0.557304.517803.71280HepG2GPKOW
SAP130ENSG00000136715.131063.105901571.02220-0.563409.769608.20970HepG2HNRNPA2B1
SAP130ENSG00000136715.13956.025601197.52730-0.324902.315201.67530HepG2HNRNPC
SAP130ENSG00000136715.131318.036401544.47820-0.228702.541501.85310HepG2HNRNPF
SAP130ENSG00000136715.131336.014701557.03400-0.220902.367301.73740HepG2HNRNPL
SAP130ENSG00000136715.131548.210302318.44140-0.582604.640603.84660HepG2HNRNPLL
SAP130ENSG00000136715.131404.840701189.607500.239802.482001.90700HepG2HNRNPU
SAP130ENSG00000136715.131270.624201520.85900-0.259302.335501.66800HepG2IGF2BP1
SAP130ENSG00000136715.131241.076001555.62990-0.325903.011402.16780HepG2MSI2
SAP130ENSG00000136715.13634.79280903.72660-0.509604.621202.78240HepG2NIP7
SAP130ENSG00000136715.131412.878701694.99550-0.262602.272701.58170HepG2NOL12
SAP130ENSG00000136715.13748.210501205.33150-0.687904.863003.51630HepG2PCBP2
SAP130ENSG00000136715.13618.26870819.49250-0.406502.447301.68610HepG2PRPF8
SAP130ENSG00000136715.131200.34280971.878700.304503.040502.47250HepG2PTBP1
SAP130ENSG00000136715.13889.939701618.06870-0.8625014.7075013.47890HepG2PUF60
SAP130ENSG00000136715.131388.533901717.70650-0.306904.519403.80180HepG2PUM1
SAP130ENSG00000136715.131424.172601716.41750-0.269302.231101.62620HepG2PUM2
SAP130ENSG00000136715.131275.625501052.483000.277302.406801.81770HepG2QKI
SAP130ENSG00000136715.131201.908201644.63340-0.452406.579005.86160HepG2RBM22
SAP130ENSG00000136715.131465.643201081.574300.438306.320105.55750HepG2NELFE
SAP130ENSG00000136715.131266.615301007.400000.330203.825503.11670HepG2RECQL
SAP130ENSG00000136715.131039.993001663.94730-0.678009.801208.64780HepG2RPLP0
SAP130ENSG00000136715.13793.260401142.69620-0.526602.949501.97630HepG2RPS10
SAP130ENSG00000136715.131043.44440865.314900.270001.834901.32420HepG2RPS19
SAP130ENSG00000136715.13533.89970810.64790-0.602504.332503.37210HepG2RRP9
SAP130ENSG00000136715.131465.703702294.90150-0.646805.550404.57810HepG2SF3B1
SAP130ENSG00000136715.131214.825401551.58880-0.353005.157304.24760HepG2SLBP
SAP130ENSG00000136715.13798.751901186.54180-0.570903.884702.73330HepG2SMNDC1
SAP130ENSG00000136715.131470.197602553.44360-0.796405.326704.23190HepG2SNRNP70
SAP130ENSG00000136715.131289.536601857.54060-0.5265011.3627010.53470HepG2SRFBP1
SAP130ENSG00000136715.131785.646701056.107800.7576019.7100018.68970HepG2SRSF1
SAP130ENSG00000136715.131087.509901597.67320-0.5549010.096009.00190HepG2SRSF5
SAP130ENSG00000136715.131132.884901517.43710-0.421606.870605.85510HepG2SRSF7
SAP130ENSG00000136715.131091.07630859.225200.344504.164603.51320HepG2SRSF9
SAP130ENSG00000136715.131369.268201612.76360-0.236102.585802.08480HepG2SSB
SAP130ENSG00000136715.13888.471101283.81740-0.531003.224901.89590HepG2STAU1
SAP130ENSG00000136715.13707.359701086.92970-0.619703.854802.42620HepG2SUB1
SAP130ENSG00000136715.13554.997601057.51850-0.930109.982108.83010HepG2SUPV3L1
SAP130ENSG00000136715.131200.77970949.352400.338902.822302.25660HepG2TAF15
SAP130ENSG00000136715.13467.80760708.81800-0.599504.285403.08130HepG2TFIP11
SAP130ENSG00000136715.13721.973801155.79800-0.678909.922709.07940HepG2TIAL1
SAP130ENSG00000136715.13810.756901166.26740-0.524605.675404.92020HepG2TRIM56
SAP130ENSG00000136715.13639.793401673.39010-1.3871023.2307020.87750HepG2UBE2L3
SAP130ENSG00000136715.13425.11680624.70920-0.555303.975403.06560HepG2UCHL5
SAP130ENSG00000136715.131295.263801679.53000-0.374805.907704.94810HepG2UPF1
SAP130ENSG00000136715.13741.964001041.01090-0.488603.643602.82070HepG2XRN2
SAP130ENSG00000136715.131186.454801650.41210-0.476209.587308.46420HepG2ZC3H8
SAP130ENSG00000136715.131052.537101847.16130-0.8114028.3773027.09470HepG2ZNF622
SAP130ENSG00000136715.131170.41840933.158100.326702.232501.30320K562CCAR1
SAP130ENSG00000136715.131631.835301927.09890-0.239902.044201.36150K562CPSF6
SAP130ENSG00000136715.13899.59130660.391400.445804.927603.88100K562EIF3G
SAP130ENSG00000136715.131390.322101839.88010-0.404204.052203.09500K562GPKOW
SAP130ENSG00000136715.131109.009001745.68230-0.654509.466108.04300K562GRSF1
SAP130ENSG00000136715.131542.596002484.78240-0.687805.172504.10030K562HSPD1
SAP130ENSG00000136715.131376.346201088.936100.337802.737801.35850K562LARP7
SAP130ENSG00000136715.132444.507201973.429800.308702.817901.89860K562MBNL1
SAP130ENSG00000136715.131497.329301784.03220-0.252802.762401.95410K562MTPAP
SAP130ENSG00000136715.131328.546902080.18190-0.646905.123003.95050K562PPIG
SAP130ENSG00000136715.131934.296702388.49100-0.304302.190701.46580K562PUF60
SAP130ENSG00000136715.131968.108902489.23710-0.338903.954402.80240K562PUM2
SAP130ENSG00000136715.131883.120801603.948200.231401.941701.42960K562RBM15
SAP130ENSG00000136715.131206.48410919.949000.391103.651902.51360K562RCC2
SAP130ENSG00000136715.13810.70270650.502800.317503.255001.53620K562RPS10
SAP130ENSG00000136715.131933.051001413.113700.451902.698401.63180K562SAFB
SAP130ENSG00000136715.131200.811101955.87290-0.7038014.5474012.78590K562SF3A3
SAP130ENSG00000136715.131096.01240872.097000.329602.317301.39720K562SRFBP1
SAP130ENSG00000136715.131218.22800918.139200.407903.662002.85450K562SRSF1
SAP130ENSG00000136715.13769.380701012.60300-0.396302.769001.56290K562XRN2
SAP130ENSG00000136715.131412.653901715.38300-0.280102.143801.39450K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SAP130 is not available on ENCORE database.





4 RBPs can affect the splicing of SAP130 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESAP130ENSG00000136715.13chr2-128750760128750882128747137128747440128753923128754144-0.067000.002490.02634excludedK562AQR
SESAP130ENSG00000136715.13chr2-128735558128735663128712559128712918128744358128744536-0.219000.000120.00290excludedK562PUS1
SESAP130ENSG00000136715.13chr2-1287355581287356631287125591287129181287443581287445360.300000.000330.01801includedHepG2MATR3
SESAP130ENSG00000136715.13chr2-128735558128735663128712559128712918128744358128744536-0.177000.004170.09725excludedK562UTP18
A3SSSAP130ENSG00000136715.13chr2-1287539231287541441287539231287540651287573141287574610.070000.000040.00041longerK562AQR
A3SSSAP130ENSG00000136715.13chr2-1287573141287575461287573141287574191287576291287577200.109000.000000.00000longerK562AQR
A3SSSAP130ENSG00000136715.13chr2-1287355581287357161287355581287356631287443581287445330.102000.004170.02466longerK562AQR
A3SSSAP130ENSG00000136715.13chr2-1286999971287002091286999971287001111287030291287031330.095000.000000.00000longerK562AQR
MXESAP130ENSG00000136715.13chr2-1287507601287508821287539231287541721287471371287474401287573141287574190.078000.001290.011351includedK562AQR
MXESAP130ENSG00000136715.13chr2-1287507601287508821287539231287541441287471371287474401287573141287574190.088000.000340.003571includedK562AQR
MXESAP130ENSG00000136715.13chr2-1287507601287508821287539231287541031287471371287474401287573141287574190.071000.001310.011571includedK562AQR
MXESAP130ENSG00000136715.13chr2-1287507601287508821287539231287540981287471371287474401287573141287574190.109000.000050.000611includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SAP130 is not avaliable on ENCORE database.