RING1

General Information

Gene Name       : RING1
Gene ID             : ENSG00000204227.4
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RING1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RING1ENSG00000204227.47.0811.479.28ENCSR000AEF
HepG2RING1ENSG00000204227.436.6322.3529.49ENCSR985KAT
K562RING1ENSG00000204227.432.8129.7431.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RING1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RING1 RNA is bound by 25 proteins.  







eCLIP assay for RING1 is not avaliable on ENCORE database.





25 proteins are bound to RING1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63318024833180296+3'-UTR3.660117.12906HepG2U2AF2
chr63318033733180400+3'-UTR6.108795.13070K562PUM2
chr63318023233180294+3'-UTR3.657486.18296HepG2U2AF1
chr63317654133176679+5'-UTR,CDS,intron-Proximal3.591697.35825K562DDX3X
chr63317630333176329+5'-UTR4.181274.17587HepG2DDX3X
chr63317630033176416+5'-UTR5.0381211.77860K562DDX3X
chr63317654333176600+5'-UTR3.427206.49759HepG2DDX3X
chr63317927033179353+CDS,intron-Proximal4.3138412.89733K562EFTUD2
chr63317926833179351+CDS,intron-Proximal3.435354.23685HepG2CDC40
chr63317999733180083+CDS,intron-Proximal3.897587.62589K562PTBP1
chr63317967133179722+CDS3.255415.36952HepG2GTF2F1
chr63318002433180110+CDS,intron-Proximal4.860016.76879K562U2AF2
chr63317903233179076+CDS4.3234015.35644HepG2PRPF4
chr63317916833179248+CDS4.064885.76824HepG2CDC40
chr63317899133179077+CDS3.526184.61081K562GTF2F1
chr63317902833179081+CDS4.6434210.18833HepG2EFTUD2
chr63317892333178969+CDS,intron-Proximal3.598118.36543HepG2U2AF2
chr63317741033177501+CDS4.043663.69113K562LIN28B
chr63317997033180082+CDS,intron-Distal,intron-Proximal4.2768418.48769HepG2PTBP1
chr63317955833179612+CDS4.428593.48187K562RBM15
chr63317915333179196+CDS3.996906.87708HepG2EFTUD2
chr63317919733179251+CDS5.3183420.10760HepG2PRPF4
chr63317965133179749+CDS3.739758.72457K562RBM15
chr63317974633179778+CDS4.531789.41951HepG2PPIG
chr63317966833179715+CDS3.763576.03664K562GTF2F1
chr63317944533179507+CDS,intron-Proximal5.197027.19196HepG2SF3B4
chr63317913633179206+CDS4.239256.83823K562DDX24
chr63317965933179713+CDS3.956667.09030K562SF3B4
chr63317776233177867+CDS3.357618.08507HepG2GRWD1
chr63317977633179810+CDS,intron-Proximal4.888895.65342K562AQR
chr63317899233179032+CDS3.512509.73722HepG2PRPF4
chr63317914033179167+CDS4.312569.49794HepG2PRPF4
chr63317967533179736+CDS3.430663.44687K562SRSF1
chr63317919733179240+CDS3.991934.76561K562GEMIN5
chr63317892233178974+CDS,intron-Proximal3.794297.45960K562U2AF2
chr63317920333179266+CDS3.832677.87052K562GTF2F1
chr63317965333179724+CDS3.131264.18590HepG2RBM15
chr63317966533179721+CDS5.3507321.49121HepG2PRPF4
chr63317898933179079+CDS3.026137.02731HepG2FAM120A
chr63317913933179189+CDS3.794217.78072K562GTF2F1
chr63317772133177762+CDS3.645325.14253HepG2GRWD1
chr63317916733179196+CDS4.8340213.90432HepG2PRPF4
chr63317892333178970+CDS,intron-Proximal4.555115.12844K562U2AF1
chr63317915633179243+CDS3.497454.39249K562RBFOX2
chr63317999433180121+CDS,intron-Proximal4.5491245.84257HepG2U2AF2
chr63317917333179242+CDS3.403483.01032HepG2LARP4
chr63317967633179707+CDS3.259093.40321HepG2GRWD1
chr63317763533177712+CDS,intron-Proximal4.132403.79177K562SMNDC1
chr63317974833179807+CDS,intron-Proximal3.3102017.99336HepG2PRPF8
chr63317966833179719+CDS3.462515.82980HepG2FASTKD2
chr63318007533180102+CDS5.4309610.41518HepG2PPIG
chr63317900133179067+CDS3.897005.20093K562DDX24
chr63317761633177734+CDS,intron-Proximal3.170064.47384HepG2AQR
chr63317919633179245+CDS3.582368.81681HepG2EFTUD2
chr63317914933179191+CDS4.716295.56287HepG2GTF2F1
chr63317966733179729+CDS3.6947015.47743HepG2PPIG
chr63317966533179729+CDS3.138014.96230HepG2SRSF1
chr63317881933178931+intron-Distal,intron-Proximal3.401584.08064K562KHSRP
chr63317945733179505+intron-Proximal5.230168.54916K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RING1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RING1 is not available on ENCORE database.

  • 76 RBPs can affect the levels of RING1.  








The Knockdown/knockout RNA-Seq assay for RING1 is not available on ENCORE database.





76 RBPs can affect the gene expression of RING1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RING1ENSG00000204227.41257.09560912.856100.461503.292802.26760HepG2ABCF1
RING1ENSG00000204227.41951.454301163.086600.746507.700006.85970HepG2AKAP1
RING1ENSG00000204227.41041.39710833.498400.321203.109702.30200HepG2AKAP8L
RING1ENSG00000204227.41286.16790962.295200.418402.975602.16130HepG2ASCC1
RING1ENSG00000204227.41082.523101306.70280-0.271502.564301.89970HepG2AUH
RING1ENSG00000204227.41085.21720669.965500.695705.257803.95920HepG2BCCIP
RING1ENSG00000204227.4453.634601006.68690-1.1500018.7401017.39060HepG2BOP1
RING1ENSG00000204227.41323.92870914.266500.534004.768003.76730HepG2CIRBP
RING1ENSG00000204227.4970.72230829.427000.226802.042401.45880HepG2CKAP4
RING1ENSG00000204227.41123.94700833.264200.431605.581304.72910HepG2CELF1
RING1ENSG00000204227.41126.29530895.849700.330204.433503.53010HepG2DAZAP1
RING1ENSG00000204227.41274.03610957.273800.412302.610202.01020HepG2DDX6
RING1ENSG00000204227.41073.99840793.682500.436305.396804.50830HepG2DKC1
RING1ENSG00000204227.4804.29220559.078300.524603.282702.28600HepG2EEF2
RING1ENSG00000204227.4876.51230692.433400.340002.505601.39710HepG2EIF2S2
RING1ENSG00000204227.41306.545801016.496500.362102.105801.54580HepG2EIF4A3
RING1ENSG00000204227.41887.745601500.234100.331404.480503.74930HepG2ETF1
RING1ENSG00000204227.41326.56560921.752600.525103.994103.08340HepG2FIP1L1
RING1ENSG00000204227.41196.06620951.577300.329801.907401.35010HepG2G3BP1
RING1ENSG00000204227.4606.82340404.020200.586704.260203.13660HepG2GEMIN5
RING1ENSG00000204227.4874.89420429.726301.0256014.6094013.31490HepG2HNRNPA1
RING1ENSG00000204227.4706.78130477.973600.564204.542903.66960HepG2HNRNPC
RING1ENSG00000204227.4735.01010964.11100-0.391402.775002.07620HepG2HNRNPK
RING1ENSG00000204227.41069.58540816.016000.390305.630204.69810HepG2HNRNPL
RING1ENSG00000204227.4881.85400474.814800.8931017.5187016.09650HepG2HNRNPU
RING1ENSG00000204227.4708.43530485.010600.546507.536906.39060HepG2ILF2
RING1ENSG00000204227.4626.08260470.007200.413603.580802.62930HepG2PARN
RING1ENSG00000204227.4496.71980375.281000.404402.585601.39930HepG2PKM
RING1ENSG00000204227.4564.60970423.499900.414803.282702.48540HepG2PPIL4
RING1ENSG00000204227.41086.79430924.505300.233202.088501.60060HepG2PTBP1
RING1ENSG00000204227.41177.53320900.246700.387306.158605.34690HepG2PUM1
RING1ENSG00000204227.41115.30040899.566200.310002.742002.07450HepG2PUM2
RING1ENSG00000204227.41129.81120844.975200.419005.800804.96800HepG2PUS1
RING1ENSG00000204227.4751.56000441.615100.767008.649507.63540HepG2RPS19
RING1ENSG00000204227.4988.28570669.793800.561102.164601.45160HepG2RPS2
RING1ENSG00000204227.4815.97570555.150300.555503.391402.50620HepG2RPS3A
RING1ENSG00000204227.4595.09270443.133100.425302.512101.61400HepG2SERBP1
RING1ENSG00000204227.4695.90900989.51690-0.507804.335603.46990HepG2SF3B1
RING1ENSG00000204227.4718.13690493.136400.542207.044106.09080HepG2SMN1
RING1ENSG00000204227.41006.798201416.27590-0.492308.012507.28210HepG2SRFBP1
RING1ENSG00000204227.41133.19990837.339700.436406.057705.18330HepG2SRSF5
RING1ENSG00000204227.41694.287201229.685600.462308.495807.69340HepG2SSB
RING1ENSG00000204227.41179.45070952.248000.308603.683602.98360HepG2SUCLG1
RING1ENSG00000204227.41157.44410655.722200.819707.593006.56370HepG2SUPV3L1
RING1ENSG00000204227.4681.59350903.09370-0.406003.736503.10130HepG2TAF15
RING1ENSG00000204227.41313.81290846.152100.634702.651501.60490HepG2TBRG4
RING1ENSG00000204227.4958.70890461.436601.0549016.7183015.67670HepG2TIAL1
RING1ENSG00000204227.4584.26330465.491400.327802.579402.03070HepG2TRIM56
RING1ENSG00000204227.41113.26310828.539100.426104.214203.10810HepG2TUFM
RING1ENSG00000204227.4528.16890387.319700.447402.384601.67920HepG2UCHL5
RING1ENSG00000204227.41252.84790782.651000.6787011.6523010.55760HepG2UTP3
RING1ENSG00000204227.41051.47220645.488100.703806.099905.03700HepG2XRN2
RING1ENSG00000204227.4937.78840773.857200.277102.752802.08200HepG2ZC3H8
RING1ENSG00000204227.41696.377801311.835700.370803.216501.87900K562APOBEC3C
RING1ENSG00000204227.41620.499901163.733700.477608.153707.11260K562DDX47
RING1ENSG00000204227.41290.23960974.854800.404304.851703.93540K562EIF2S2
RING1ENSG00000204227.4640.76820420.404900.607903.872102.93980K562EIF3G
RING1ENSG00000204227.4857.58610581.386800.560705.381004.23840K562EIF4A3
RING1ENSG00000204227.41405.72320822.896700.7724010.742608.95030K562FIP1L1
RING1ENSG00000204227.4801.20380604.617100.406003.838403.14320K562FXR1
RING1ENSG00000204227.4147.14530341.95300-1.216608.369107.00120K562G3BP2
RING1ENSG00000204227.41592.582601298.994300.293902.236201.55290K562GRSF1
RING1ENSG00000204227.41199.74410673.683900.8325012.7572011.55200K562HNRNPC
RING1ENSG00000204227.41314.298901051.644600.321502.637001.60900K562HNRNPL
RING1ENSG00000204227.4965.50750676.813300.512403.732202.63890K562HNRNPM
RING1ENSG00000204227.41498.868001031.878200.538508.268306.73200K562HNRNPU
RING1ENSG00000204227.41627.872301115.716700.544905.765704.63220K562HSPD1
RING1ENSG00000204227.4717.34250537.637800.415903.120902.22730K562MAGOH
RING1ENSG00000204227.4772.79400536.501300.526405.068703.77560K562MATR3
RING1ENSG00000204227.4580.08670817.47830-0.494902.832801.93840K562NAA15
RING1ENSG00000204227.41207.87870934.105900.370702.800301.97290K562PPIG
RING1ENSG00000204227.4812.18110617.495300.395302.444101.73800K562PRPF8
RING1ENSG00000204227.4791.50900604.013900.389902.469901.62140K562PSIP1
RING1ENSG00000204227.4850.14790522.371300.702508.936007.78560K562PTBP1
RING1ENSG00000204227.4717.81280500.727200.519502.793401.94900K562RBM22
RING1ENSG00000204227.4728.79370526.973700.467703.403302.17520K562NELFE
RING1ENSG00000204227.4892.81510628.900300.505403.273702.38300K562RPS19
RING1ENSG00000204227.4696.06360521.562200.416302.275001.37790K562RPS3
RING1ENSG00000204227.41066.56420758.251600.492104.823503.39240K562SAFB
RING1ENSG00000204227.4693.10830522.355300.407902.720101.70680K562SRFBP1
RING1ENSG00000204227.4909.97390512.131800.8292011.398509.97520K562SRSF1
RING1ENSG00000204227.41076.40230853.521500.334602.849102.01600K562SYNCRIP
RING1ENSG00000204227.4920.81970518.238000.829206.260905.15770K562TARDBP
RING1ENSG00000204227.4716.11140499.918200.518404.642803.54180K562TIA1
RING1ENSG00000204227.4648.09290490.740900.401102.379401.38200K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RING1 is not available on ENCORE database.





8 RBPs can affect the splicing of RING1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERING1ENSG00000204227.4chr6+331789343317932433177691331779073317950533179779-0.210000.000230.00621excludedK562SF3B4
SERING1ENSG00000204227.4chr6+331789343317932433177691331779073317950533179779-0.052000.002100.03132excludedK562PUS1
SERING1ENSG00000204227.4chr6+331789343317932433177691331779073317950533179779-0.056000.000350.01542excludedK562UTP18
SERING1ENSG00000204227.4chr6+331789343317932433177691331779073317950533179779-0.274000.000360.00852excludedK562U2AF2
SERING1ENSG00000204227.4chr6+331789343317932433177691331779073317950533179779-0.064000.000990.02758excludedK562AGGF1
A5SSRING1ENSG00000204227.4chr6+3317740233177599331774023317756333177691331779070.079000.000010.00160longerHepG2SRSF9
A5SSRING1ENSG00000204227.4chr6+3317740233177599331774023317756333177691331779070.055000.000230.02506longerHepG2SF3B4
MXERING1ENSG00000204227.4chr6+3317740233177563331776913317790733176541331766773317893433179324-0.099000.000000.000002includedHepG2U2AF2
MXERING1ENSG00000204227.4chr6+3317740233177563331776913317790733176541331766773317893433179324-0.082000.000000.000012includedHepG2RBFOX2
MXERING1ENSG00000204227.4chr6+3317740233177563331776913317790733176541331766773317893433179324-0.179000.000040.002622includedHepG2SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RING1 is not avaliable on ENCORE database.