RB1

General Information

Gene Name       : RB1
Gene ID             : ENSG00000139687.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RB1ENSG00000139687.156.696.986.84ENCSR000AEF
HepG2RB1ENSG00000139687.159.5321.6515.59ENCSR985KAT
K562RB1ENSG00000139687.1512.2214.2313.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RB1 RNA is bound by 14 proteins.  







eCLIP assay for RB1 is not avaliable on ENCORE database.





14 proteins are bound to RB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr134905588849055979+3'-UTR5.020586.28020HepG2FUBP3
chr134893415248934265+3'-UTR,CDS,intron-Proximal3.391509.52893HepG2BCLAF1
chr134905456749054669+3'-UTR3.155357.99848K562PUM2
chr134893695248937006+3'-UTR,CDS4.980335.23259HepG2BCLAF1
chr134887794348878110+5'-UTR,CDS3.512814.84203K562DDX3X
chr134887802648878143+5'-UTR,CDS3.878443.33043HepG2NCBP2
chr134887794448878016+5'-UTR3.621786.05537HepG2DDX3X
chr134895111148951172+CDS,intron-Proximal3.680176.60490HepG2BCLAF1
chr134891921548919224+CDS,intron-Distal,intron-Proximal4.337623.89826HepG2BCLAF1
chr134893906948939110+CDS,intron-Proximal3.395364.74886HepG2BCLAF1
chr134895555348955610+CDS,intron-Proximal5.103884.68690HepG2PRPF8
chr134891673348916850+CDS,intron-Distal,intron-Proximal4.9038716.00085HepG2BCLAF1
chr134891930548919334+CDS,intron-Distal3.191534.34695HepG2BCLAF1
chr134892310948923148+CDS,intron-Distal3.872825.35703HepG2BCLAF1
chr134888150648881541+CDS,intron-Distal3.788664.51739HepG2BCLAF1
chr134892196048921975+CDS,intron-Distal,intron-Proximal3.526883.87469HepG2BCLAF1
chr134891673348916851+CDS,intron-Distal,intron-Proximal4.419195.64870K562DDX24
chr134888753948887586+intron-Distal3.770023.16028HepG2SUGP2
chr134894401348944130+intron-Distal4.918775.89032HepG2QKI
chr134904573049045819+intron-Distal3.864283.93850HepG2CSTF2
chr134887853148878598+intron-Distal3.810005.55220K562CSTF2T
chr134889847148898534+intron-Distal3.952555.08047HepG2QKI
chr134898024148980399+intron-Distal4.423174.66266K562TARDBP
chr134896375448963828+intron-Distal3.556583.12080HepG2XPO5
chr134896514548965201+intron-Distal4.478053.91475K562PTBP1
chr134889262448892735+intron-Distal3.965753.29248HepG2SUGP2
chr134896405248964102+intron-Distal4.411833.37054HepG2XPO5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RB1 is not available on ENCORE database.

  • 111 RBPs can affect the levels of RB1.  








The Knockdown/knockout RNA-Seq assay for RB1 is not available on ENCORE database.





111 RBPs can affect the gene expression of RB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RB1ENSG00000139687.91607.872701084.583700.567905.885904.37920HepG2AATF
RB1ENSG00000139687.91063.330701359.99790-0.355002.339801.42060HepG2ADAR
RB1ENSG00000139687.9699.783601280.92000-0.872203.868001.89650HepG2APOBEC3C
RB1ENSG00000139687.91118.335401531.88650-0.454003.665702.76430HepG2ASCC1
RB1ENSG00000139687.9668.554601339.11980-1.002207.364505.79580HepG2BCCIP
RB1ENSG00000139687.91220.928201900.42170-0.638308.399707.42600HepG2BOP1
RB1ENSG00000139687.91272.464901627.75300-0.355303.178902.35750HepG2CALR
RB1ENSG00000139687.91072.128901455.38310-0.440903.535602.66860HepG2CIRBP
RB1ENSG00000139687.9959.822501744.73100-0.8622011.4055010.11700HepG2CPSF6
RB1ENSG00000139687.91011.752301358.43300-0.425102.743301.64230HepG2CPSF7
RB1ENSG00000139687.91059.220901394.61620-0.396904.147002.89540HepG2YBX3
RB1ENSG00000139687.91338.248301706.51950-0.350704.819204.01450HepG2CELF1
RB1ENSG00000139687.9742.796501835.21320-1.3049042.0316039.81640HepG2DAZAP1
RB1ENSG00000139687.9883.156001235.99110-0.484908.533907.21230HepG2DDX19B
RB1ENSG00000139687.91374.792501773.55570-0.367402.587901.98110HepG2DDX3X
RB1ENSG00000139687.9819.330101316.55860-0.684305.137504.12300HepG2DDX55
RB1ENSG00000139687.91166.673301546.65970-0.406803.462502.34130HepG2DDX5
RB1ENSG00000139687.9827.070201320.86800-0.675408.198706.60570HepG2DHX30
RB1ENSG00000139687.9916.346601278.59250-0.480606.316505.37250HepG2DKC1
RB1ENSG00000139687.91047.897501369.52770-0.386204.232703.37820HepG2DNAJC21
RB1ENSG00000139687.91044.860501357.26130-0.377403.488102.77030HepG2DNAJC2
RB1ENSG00000139687.91030.542101464.60490-0.507104.355803.62130HepG2EIF2S1
RB1ENSG00000139687.9825.176201618.67030-0.9720012.3111010.99330HepG2EIF4A3
RB1ENSG00000139687.91188.933601575.79320-0.406402.226201.60550HepG2EIF4B
RB1ENSG00000139687.91889.460402180.23780-0.206502.111001.57120HepG2ETF1
RB1ENSG00000139687.9856.593401305.90220-0.608407.782406.38750HepG2EWSR1
RB1ENSG00000139687.91131.157501514.87170-0.421403.000902.30950HepG2G3BP1
RB1ENSG00000139687.91559.987401977.89890-0.342402.242301.66180HepG2GPKOW
RB1ENSG00000139687.9841.638601537.88090-0.8697013.9207012.48010HepG2HNRNPC
RB1ENSG00000139687.9983.925501533.53680-0.640207.264206.17260HepG2HNRNPK
RB1ENSG00000139687.91031.653501671.82550-0.6965014.5567013.12020HepG2HNRNPL
RB1ENSG00000139687.91038.939701539.89620-0.567705.377504.46390HepG2IGF2BP2
RB1ENSG00000139687.9668.452401444.87570-1.112004.678803.40760HepG2IGF2BP3
RB1ENSG00000139687.91270.740901560.52280-0.296403.134602.35850HepG2ILF2
RB1ENSG00000139687.9883.906401337.17210-0.597203.921702.32060HepG2ILF3
RB1ENSG00000139687.91096.908401548.75610-0.497703.262702.16210HepG2KHSRP
RB1ENSG00000139687.91013.877301221.64430-0.268903.153902.06700HepG2KIF1C
RB1ENSG00000139687.91932.775002643.64640-0.451903.069402.19150HepG2LARP4
RB1ENSG00000139687.91195.414701633.40680-0.450403.582402.83540HepG2MAGOH
RB1ENSG00000139687.91277.119401681.33930-0.396702.804202.16720HepG2NCBP2
RB1ENSG00000139687.91242.810901819.77830-0.550209.298607.92580HepG2NOL12
RB1ENSG00000139687.91308.063801673.58090-0.355502.840002.08130HepG2NSUN2
RB1ENSG00000139687.9821.746401253.55310-0.609303.292702.31910HepG2PABPC1
RB1ENSG00000139687.9869.103101497.54420-0.785009.250507.94890HepG2PABPC4
RB1ENSG00000139687.91250.179501512.25070-0.274602.618801.79150HepG2PARN
RB1ENSG00000139687.91084.147401461.22920-0.430606.584905.70950HepG2PCBP1
RB1ENSG00000139687.9730.947901362.61210-0.8985015.2285013.57130HepG2PPIL4
RB1ENSG00000139687.9517.590001191.19730-1.2025034.2766032.17400HepG2PRPF4
RB1ENSG00000139687.9769.938901016.02190-0.400102.114101.40350HepG2PRPF8
RB1ENSG00000139687.91865.167201486.825600.327004.260503.61330HepG2PTBP1
RB1ENSG00000139687.91394.682401737.05840-0.316702.922202.31240HepG2PUF60
RB1ENSG00000139687.91292.155801842.58220-0.511905.137704.23720HepG2PUM2
RB1ENSG00000139687.91667.117201361.235300.292303.928603.21930HepG2PUS1
RB1ENSG00000139687.91044.384901605.05190-0.620003.078502.03140HepG2RBM27
RB1ENSG00000139687.9926.212401303.36640-0.492802.449601.45310HepG2RCC2
RB1ENSG00000139687.9834.066201015.50530-0.284001.909601.39090HepG2RPS19
RB1ENSG00000139687.9864.365801480.40290-0.776305.159404.08630HepG2RPS2
RB1ENSG00000139687.9761.646101360.53390-0.8370015.5827014.23980HepG2SAFB2
RB1ENSG00000139687.91440.174701868.35080-0.375503.244102.48520HepG2SF3B1
RB1ENSG00000139687.91243.194301665.37740-0.421807.616206.54090HepG2SLBP
RB1ENSG00000139687.91053.118501586.66950-0.591308.746907.70470HepG2SMN1
RB1ENSG00000139687.92302.791801615.787100.5110011.0510010.24280HepG2SRSF1
RB1ENSG00000139687.91318.535501714.98080-0.379304.662803.88600HepG2SRSF5
RB1ENSG00000139687.91646.031201950.50090-0.244903.669702.97090HepG2SUCLG1
RB1ENSG00000139687.9780.952501124.76790-0.526303.790102.70230HepG2SUPT6H
RB1ENSG00000139687.9909.778401310.73070-0.526803.263802.53630HepG2SUPV3L1
RB1ENSG00000139687.9978.911201452.27200-0.569109.277608.34680HepG2TAF15
RB1ENSG00000139687.9790.168801839.46990-1.2191022.6192020.92680HepG2TARDBP
RB1ENSG00000139687.9582.60730878.60810-0.592703.693602.56150HepG2TFIP11
RB1ENSG00000139687.91081.591601484.67860-0.457005.227204.58510HepG2TIAL1
RB1ENSG00000139687.9851.452001497.71920-0.8148014.4071013.26210HepG2TRIM56
RB1ENSG00000139687.9898.427501796.02180-0.9993014.4764012.52930HepG2UBE2L3
RB1ENSG00000139687.9488.40510774.36890-0.664904.756903.75550HepG2UCHL5
RB1ENSG00000139687.9657.026101200.53630-0.869705.184303.78630HepG2UPF2
RB1ENSG00000139687.91010.381101324.67400-0.390705.269204.48730HepG2UTP3
RB1ENSG00000139687.9859.075501233.13490-0.521503.356602.14030HepG2XPO5
RB1ENSG00000139687.92216.883501469.162200.593404.207002.64410HepG2XRCC5
RB1ENSG00000139687.9562.398401290.26710-1.1980010.895009.47100HepG2XRN2
RB1ENSG00000139687.91575.675601175.562200.422507.499406.48230HepG2ZC3H8
RB1ENSG00000139687.91248.815301509.00730-0.273003.734903.12470HepG2ZNF622
RB1ENSG00000139687.91137.026101450.87340-0.351704.667003.96390K562AGGF1
RB1ENSG00000139687.91276.710801594.16040-0.320402.752301.77410K562AKAP8
RB1ENSG00000139687.91073.991101509.66750-0.491205.398604.46910K562AKAP8L
RB1ENSG00000139687.9983.144501900.90310-0.9512018.2819015.29270K562APOBEC3C
RB1ENSG00000139687.91179.699601775.99560-0.590207.161706.28760K562AQR
RB1ENSG00000139687.91297.890501583.94420-0.287402.759201.84700K562ATP5C1
RB1ENSG00000139687.91110.219001454.13210-0.389303.973603.03410K562CPSF6
RB1ENSG00000139687.9595.81900759.13040-0.349502.719501.67000K562CSTF2
RB1ENSG00000139687.9626.14910880.21820-0.491404.581303.19080K562DDX3X
RB1ENSG00000139687.9654.56190892.43810-0.447203.207201.77480K562DDX6
RB1ENSG00000139687.91304.401801624.71120-0.316803.212102.25950K562DKC1
RB1ENSG00000139687.9817.84760972.30830-0.249602.076701.37950K562EIF3G
RB1ENSG00000139687.9504.08500919.63210-0.8674011.588909.87400K562EIF4A3
RB1ENSG00000139687.9615.50610828.19890-0.428204.124302.66390K562EIF4B
RB1ENSG00000139687.9734.63170926.96930-0.335502.660301.42020K562EXOSC5
RB1ENSG00000139687.91046.136901386.41330-0.406303.567902.59550K562FIP1L1
RB1ENSG00000139687.91390.61150998.553100.477703.091702.33670K562G3BP2
RB1ENSG00000139687.91083.009601795.14480-0.729108.031306.73140K562GRSF1
RB1ENSG00000139687.9927.626901306.60040-0.494203.233601.88770K562HNRNPK
RB1ENSG00000139687.9940.437401653.96490-0.8145014.1871011.69560K562HNRNPL
RB1ENSG00000139687.9792.842001140.32970-0.524304.133202.97960K562HNRNPM
RB1ENSG00000139687.9913.789501307.28810-0.516603.389302.20980K562IGF2BP2
RB1ENSG00000139687.9942.277401329.99750-0.497202.968801.72260K562IGF2BP3
RB1ENSG00000139687.9843.486601374.67140-0.704605.266504.09710K562MAGOH
RB1ENSG00000139687.91375.989901794.90550-0.383404.194503.03790K562MBNL1
RB1ENSG00000139687.91093.281201330.03640-0.282803.708502.85880K562NSUN2
RB1ENSG00000139687.9597.78800870.36720-0.542004.752402.67270K562NUSAP1
RB1ENSG00000139687.9906.457501223.25650-0.432402.707001.73840K562PCBP2
RB1ENSG00000139687.91576.083301179.100300.418603.126302.24130K562PCBP3
RB1ENSG00000139687.91176.10000904.401200.378903.697002.76440K562POLR2G
RB1ENSG00000139687.91034.316001573.83160-0.605607.131605.69880K562PPIG
RB1ENSG00000139687.9595.34190784.30160-0.397702.072001.41850K562PRPF8
RB1ENSG00000139687.9484.35930792.65530-0.710606.882105.34110K562PSIP1
RB1ENSG00000139687.93084.198602500.200500.302802.357501.37900K562PUM1
RB1ENSG00000139687.91185.608401497.40510-0.336802.838502.28990K562PUS1
RB1ENSG00000139687.91076.370301458.80580-0.438603.621202.95590K562RBM15
RB1ENSG00000139687.9936.302201281.02330-0.452302.426901.64230K562RBM22
RB1ENSG00000139687.9757.063501013.98850-0.421603.582301.63940K562RECQL
RB1ENSG00000139687.9653.237901055.67960-0.692502.719901.53260K562SF1
RB1ENSG00000139687.91077.521201312.43470-0.284502.690501.88630K562SF3A3
RB1ENSG00000139687.9769.519901038.39180-0.432304.433103.34050K562SF3B4
RB1ENSG00000139687.9533.27920759.60900-0.510402.923601.87630K562SUPV3L1
RB1ENSG00000139687.9863.058601325.15160-0.618603.849303.00870K562TARDBP
RB1ENSG00000139687.9944.513601278.20980-0.436502.220201.49350K562TIA1
RB1ENSG00000139687.9937.677901253.86710-0.419202.510801.48060K562TRA2A
RB1ENSG00000139687.9729.81560968.00370-0.407502.568201.52070K562U2AF1
RB1ENSG00000139687.9760.413501206.71870-0.666209.060307.43720K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RB1 is not available on ENCORE database.





1 RBPs can affect the splicing of RB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERB1ENSG00000139687.9chr13+490514904905154049050814490509794905413349054783-0.074000.000030.00068excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RB1 is not avaliable on ENCORE database.