PTPRU

General Information

Gene Name       : PTPRU
Gene ID             : ENSG00000060656.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTPRU)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPRUENSG00000060656.190.070.180.12ENCSR000AEF
HepG2PTPRUENSG00000060656.1945.1112.2528.68ENCSR985KAT
K562PTPRUENSG00000060656.191.240.881.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPRU is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTPRU RNA is bound by 21 proteins.  







eCLIP assay for PTPRU is not avaliable on ENCORE database.





21 proteins are bound to PTPRU RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12965276729652952+3'-UTR6.1716336.36859HepG2UPF1
chr12965234329652366+3'-UTR4.543805.64948HepG2UPF1
chr12965319829653261+3'-UTR5.0803816.34518HepG2UPF1
chr12965289429652957+3'-UTR3.908175.09002HepG2FAM120A
chr12965279529652897+3'-UTR3.7764213.71754HepG2DDX55
chr12965276729652824+3'-UTR4.358049.26660HepG2AKAP1
chr12965214729652207+3'-UTR,CDS4.282409.32514HepG2UPF1
chr12965286329652949+3'-UTR3.333337.93458HepG2STAU2
chr12965220729652259+3'-UTR5.167769.25213HepG2UPF1
chr12965267929652767+3'-UTR6.4972421.61956HepG2UPF1
chr12965313829653198+3'-UTR5.8566515.42180HepG2UPF1
chr12965322029653249+3'-UTR3.247323.58777HepG2DDX55
chr12965282629652914+3'-UTR3.490496.16969HepG2LARP4
chr12965267529652757+3'-UTR4.6251612.51074HepG2AKAP1
chr12965313129653259+3'-UTR5.6836612.33273K562UPF1
chr12965299029653037+3'-UTR3.942786.36332HepG2UPF1
chr12965313029653193+3'-UTR3.9490910.74067HepG2AKAP1
chr12965282429652935+3'-UTR4.6803015.39562HepG2AKAP1
chr12965321429653262+3'-UTR4.5607910.03265HepG2AKAP1
chr12965312929653247+3'-UTR3.2403410.65066HepG2LARP4
chr12956315229563230+5'-UTR,CDS,intron-Proximal4.8921216.80562HepG2DDX3X
chr12956305029563152+5'-UTR6.0240827.97203HepG2DDX3X
chr12965165729651731+CDS,intron-Proximal4.406473.95187HepG2AQR
chr12963129829631360+CDS3.550705.30777HepG2PPIG
chr12964425829644319+CDS,intron-Proximal5.011146.71475HepG2LIN28B
chr12963055529630594+CDS,intron-Proximal4.683715.93128HepG2PRPF8
chr12958179629581832+CDS3.270003.32039HepG2PPIG
chr12958702529587139+CDS,intron-Proximal3.466294.10684HepG2AQR
chr12961847629618513+CDS3.575513.59112HepG2PPIG
chr12965028929650355+CDS,intron-Proximal5.015195.68502HepG2PRPF8
chr12958178629581844+CDS,intron-Proximal4.861229.03779HepG2DDX3X
chr12964443029644492+CDS,intron-Proximal3.502424.83899HepG2PRPF8
chr12960659229606655+CDS,intron-Proximal4.091935.80295HepG2PPIG
chr12958663529586691+intron-Distal,intron-Proximal4.353933.13028HepG2FAM120A
chr12960976929609907+intron-Distal4.7309317.96537HepG2HNRNPK
chr12960957029609652+intron-Distal5.303039.77805HepG2HNRNPK
chr12957259429572632+intron-Distal4.899286.34754HepG2RBFOX2
chr12957266629572787+intron-Distal4.388275.13416HepG2DROSHA
chr12957226929572335+intron-Distal5.2092619.14156HepG2RBFOX2
chr12956413229564193+intron-Distal3.869223.52163HepG2IGF2BP1
chr12957702729577137+intron-Distal4.354394.80665HepG2QKI
chr12960976829609878+intron-Distal6.2612816.72145HepG2DDX59
chr12956484529564987+intron-Distal3.437838.17012HepG2CSTF2T
chr12957234729572427+intron-Distal4.907164.72138HepG2DROSHA
chr12957257729572666+intron-Distal5.367776.55621HepG2DROSHA
chr12960965229609769+intron-Distal4.2014911.83825HepG2HNRNPK
chr12958689329587011+intron-Distal4.947498.32512HepG2PRPF4
chr12957249929572564+intron-Distal6.1523815.67571HepG2RBFOX2
chr12960963329609708+intron-Distal4.409216.20526HepG2DDX59
chr12956399129564062+intron-Distal3.383543.85040HepG2IGF2BP1
chr12957147329571504+intron-Distal3.873053.14375HepG2RBFOX2
chr12957353329573669+intron-Distal5.154769.07158HepG2RBFOX2
chr12960989329609975+intron-Distal4.973859.96448HepG2DDX59
chr12957267829572761+intron-Distal5.2177019.14156HepG2RBFOX2
chr12957197329572068+intron-Distal4.6610610.35072HepG2RBFOX2
chr12961006129610130+intron-Distal4.277704.74496HepG2DDX59
chr12957241429572499+intron-Distal5.4376921.62069HepG2RBFOX2
chr12956399529564041+intron-Distal5.954147.30436HepG2DKC1
chr12957210129572221+intron-Distal6.0400013.43272HepG2RBFOX2
chr12958631329586366+intron-Proximal4.312884.07325HepG2SF3B4
chr12960951229609552+intron-Proximal3.638934.24164HepG2DDX59
chr12964981829649874+intron-Proximal4.040486.57490HepG2SF3B4
chr12963788229637951+intron-Proximal4.021563.50006HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTPRU is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPRU is not available on ENCORE database.

  • 88 RBPs can affect the levels of PTPRU.  








The Knockdown/knockout RNA-Seq assay for PTPRU is not available on ENCORE database.





88 RBPs can affect the gene expression of PTPRU :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPRUENSG00000060656.152910.636902114.152100.461203.712802.62840HepG2ABCF1
PTPRUENSG00000060656.151485.633701038.950400.515903.150202.09090HepG2ADAR
PTPRUENSG00000060656.15758.131101334.25970-0.815509.125907.84500HepG2CALR
PTPRUENSG00000060656.15849.676401500.66820-0.820605.543604.47190HepG2CIRBP
PTPRUENSG00000060656.151254.86680668.002000.909505.351603.92510HepG2CSTF2
PTPRUENSG00000060656.15613.428401090.85410-0.830504.342002.50290HepG2CSTF2T
PTPRUENSG00000060656.15748.334601173.53130-0.649106.363405.38340HepG2DDX21
PTPRUENSG00000060656.15741.839301149.49150-0.631804.277503.13090HepG2DDX24
PTPRUENSG00000060656.15449.73770995.26950-1.146002.968501.63520HepG2DDX27
PTPRUENSG00000060656.151288.784901696.90500-0.396903.326702.22550HepG2DDX5
PTPRUENSG00000060656.152279.630601571.368200.536703.579802.88500HepG2DDX6
PTPRUENSG00000060656.15884.442101036.98570-0.229602.249101.64860HepG2DNAJC2
PTPRUENSG00000060656.15769.347001145.33290-0.574105.393904.16360HepG2EIF3D
PTPRUENSG00000060656.151124.144601443.76420-0.361004.237803.24430HepG2EIF4G1
PTPRUENSG00000060656.151995.372801383.013200.528706.050604.86790HepG2EIF4G2
PTPRUENSG00000060656.151888.806302340.53110-0.309402.855502.24630HepG2ETF1
PTPRUENSG00000060656.15740.138701118.91160-0.596203.809102.49690HepG2FASTKD2
PTPRUENSG00000060656.151361.133402134.62350-0.649204.946003.94360HepG2FIP1L1
PTPRUENSG00000060656.151137.336501561.89120-0.457602.502401.86770HepG2G3BP1
PTPRUENSG00000060656.151350.403201019.732700.405103.132302.17340HepG2GEMIN5
PTPRUENSG00000060656.15827.271801056.15650-0.352402.468601.85580HepG2HNRNPA1
PTPRUENSG00000060656.151061.798501344.89220-0.341003.826702.75390HepG2HNRNPA2B1
PTPRUENSG00000060656.15732.288701174.80880-0.681907.205406.12710HepG2HNRNPC
PTPRUENSG00000060656.152265.894701582.715900.517604.808903.90930HepG2HNRNPK
PTPRUENSG00000060656.15788.582101284.96590-0.704407.930106.92550HepG2HNRNPLL
PTPRUENSG00000060656.151131.025401472.34740-0.380503.104102.09880HepG2HNRNPM
PTPRUENSG00000060656.152094.206201167.039400.8435027.0133025.28190HepG2HNRNPU
PTPRUENSG00000060656.152004.354501538.708400.381304.651403.73440HepG2IGF2BP1
PTPRUENSG00000060656.151036.092501192.08700-0.202301.951601.32280HepG2ILF2
PTPRUENSG00000060656.151596.87280971.905700.716303.070301.79960HepG2KHDRBS1
PTPRUENSG00000060656.15907.591501597.03550-0.815304.723403.37830HepG2KHSRP
PTPRUENSG00000060656.151272.275401684.84120-0.405201.922801.37050HepG2MAGOH
PTPRUENSG00000060656.151126.370701726.90810-0.616506.266605.09530HepG2MSI2
PTPRUENSG00000060656.151129.486101451.02700-0.361403.138702.32810HepG2NOL12
PTPRUENSG00000060656.15841.782401543.57620-0.874805.597304.58260HepG2PABPC4
PTPRUENSG00000060656.15931.592401155.13180-0.310303.221502.31480HepG2PARN
PTPRUENSG00000060656.151082.439301706.79790-0.6570014.9532013.72410HepG2PCBP1
PTPRUENSG00000060656.151479.594601040.900700.507304.119903.23710HepG2PPIL4
PTPRUENSG00000060656.15945.110101432.33090-0.5998011.319709.90900HepG2PRPF4
PTPRUENSG00000060656.151370.423001736.72550-0.341704.973304.28480HepG2PTBP1
PTPRUENSG00000060656.151839.971401385.169100.409504.421103.68800HepG2PUF60
PTPRUENSG00000060656.151754.119301470.461100.254403.915103.23630HepG2PUM1
PTPRUENSG00000060656.15836.737701880.92760-1.1686033.6886031.89820HepG2QKI
PTPRUENSG00000060656.15424.174301089.33600-1.360705.484504.51220HepG2RAVER1
PTPRUENSG00000060656.15820.014901956.22420-1.2543042.7992041.23150HepG2RBM22
PTPRUENSG00000060656.15903.471301707.05850-0.9180018.0039016.38160HepG2RBM25
PTPRUENSG00000060656.151395.411601932.81300-0.470008.330907.48370HepG2NELFE
PTPRUENSG00000060656.152419.083101683.182600.523206.724405.72590HepG2RPLP0
PTPRUENSG00000060656.151759.818901114.589800.658809.769108.70120HepG2RPS19
PTPRUENSG00000060656.151607.370701133.218600.504202.508501.74460HepG2RPS2
PTPRUENSG00000060656.151316.948101039.282600.341504.612903.81570HepG2SAFB2
PTPRUENSG00000060656.15839.974601118.45820-0.413103.274902.24890HepG2SERBP1
PTPRUENSG00000060656.152037.56450936.587401.121303.896202.22390HepG2SF1
PTPRUENSG00000060656.151836.83760910.044801.013103.022501.49510HepG2SFPQ
PTPRUENSG00000060656.151810.870901328.249500.447109.521408.34370HepG2SLBP
PTPRUENSG00000060656.151125.592502209.43610-0.9730037.2539035.96510HepG2SRFBP1
PTPRUENSG00000060656.151194.149101887.32870-0.6604015.6729014.74380HepG2SRSF1
PTPRUENSG00000060656.152502.590701367.704200.8716026.3209024.66680HepG2SRSF5
PTPRUENSG00000060656.151268.798801535.43910-0.275203.303402.71100HepG2SRSF9
PTPRUENSG00000060656.152265.682101918.231400.240102.930902.40680HepG2SSB
PTPRUENSG00000060656.152485.693401661.126200.581405.471903.73800HepG2SSRP1
PTPRUENSG00000060656.151807.718001555.412400.216802.722002.10430HepG2SUCLG1
PTPRUENSG00000060656.151104.000401558.76620-0.497706.462905.19170HepG2TIA1
PTPRUENSG00000060656.152329.124001133.884601.0384028.9205027.61890HepG2TIAL1
PTPRUENSG00000060656.151716.580001144.141200.5852012.6475011.56780HepG2TRIM56
PTPRUENSG00000060656.151083.680701825.62350-0.752405.342204.48520HepG2U2AF1
PTPRUENSG00000060656.151418.586901794.91640-0.339503.346102.20720HepG2UTP18
PTPRUENSG00000060656.15801.190701685.98970-1.0734018.6727017.32700HepG2UTP3
PTPRUENSG00000060656.15909.382901920.60450-1.0786017.5871016.50240HepG2ZNF622
PTPRUENSG00000060656.15288.45960149.197900.951007.771706.88870K562AGGF1
PTPRUENSG00000060656.15167.54410103.318900.697302.687601.59800K562CPEB4
PTPRUENSG00000060656.15269.48320167.039800.689904.674803.48920K562DKC1
PTPRUENSG00000060656.1519.23810107.36830-2.4805012.8299011.62420K562FXR1
PTPRUENSG00000060656.157.1906038.40670-2.417204.672303.70010K562G3BP2
PTPRUENSG00000060656.15120.9214042.884501.495406.417605.21200K562GPKOW
PTPRUENSG00000060656.15216.5450082.382901.394208.578007.23010K562GRSF1
PTPRUENSG00000060656.15225.33250116.572300.950706.233404.88240K562HNRNPU
PTPRUENSG00000060656.15386.02300184.560901.0645011.095709.07510K562MBNL1
PTPRUENSG00000060656.15167.27860102.457100.707103.144702.28350K562MTPAP
PTPRUENSG00000060656.15220.03070113.839900.950606.401505.32970K562NSUN2
PTPRUENSG00000060656.15255.2973067.734401.9141017.1183014.45540K562PSIP1
PTPRUENSG00000060656.15237.15070156.911900.595703.036302.03300K562PUM2
PTPRUENSG00000060656.15101.28950153.94210-0.603901.837301.37660K562PUS1
PTPRUENSG00000060656.15207.62140150.013100.468801.996801.47800K562RBM15
PTPRUENSG00000060656.15127.7712056.513001.176802.598601.80900K562RPS19
PTPRUENSG00000060656.15207.7421085.444801.281603.854301.97930K562SBDS
PTPRUENSG00000060656.15309.31550133.900701.207805.425003.32880K562SFPQ
PTPRUENSG00000060656.15119.2765056.990501.065404.246502.65350K562SLBP
PTPRUENSG00000060656.15154.4267073.605301.068904.442003.05710K562SRSF4
PTPRUENSG00000060656.1541.1686080.38840-0.965402.717901.90670K562SYNCRIP
PTPRUENSG00000060656.15131.4526057.197901.200403.484802.55030K562TIA1
PTPRUENSG00000060656.15133.4233065.153101.034004.093802.93890K562TIAL1
PTPRUENSG00000060656.1548.43960101.69650-1.070003.094601.41000K562XRCC6
PTPRUENSG00000060656.15198.51980112.553600.818604.372503.24660K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPRU is not available on ENCORE database.





2 RBPs can affect the splicing of PTPRU :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPTPRUENSG00000060656.15chr1+296379672963805629638014296380562963725529637292-0.099000.002370.05349shorterHepG2U2AF2
A5SSPTPRUENSG00000060656.15chr1+2963796729638065296379672963805629638154296382710.174000.000540.07455longerHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPRU is not avaliable on ENCORE database.