PIK3C3

General Information

Gene Name       : PIK3C3
Gene ID             : ENSG00000078142.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PIK3C3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PIK3C3ENSG00000078142.1221.5918.1019.84ENCSR000AEF
HepG2PIK3C3ENSG00000078142.1227.8034.2731.04ENCSR985KAT
K562PIK3C3ENSG00000078142.1228.4223.9926.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PIK3C3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PIK3C3 RNA is bound by 15 proteins.  







eCLIP assay for PIK3C3 is not avaliable on ENCORE database.





15 proteins are bound to PIK3C3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr183956777439567825+3'-UTR,CDS,intron-Proximal4.881366.04243HepG2BCLAF1
chr183962961139629695+3'-UTR,intron-Distal,intron-Proximal5.087288.68064HepG2QKI
chr183956782539567863+3'-UTR,CDS,intron-Proximal3.533783.28366HepG2BCLAF1
chr183962949139629585+3'-UTR,CDS,intron-Proximal3.796396.81385HepG2BCLAF1
chr183966113439661266+3'-UTR4.139076.65960HepG2BCLAF1
chr183961775939617788+5'-UTR,CDS,intron-Proximal4.783824.34038HepG2BCLAF1
chr183953520839535325+5'-UTR,CDS,intron-Proximal3.480186.46814K562ZNF622
chr183960740639607475+5'-UTR,CDS,intron-Proximal3.460647.42278HepG2BCLAF1
chr183961767739617742+5'-UTR,CDS3.337624.74886HepG2BCLAF1
chr183964468339644731+5'-UTR,CDS,intron-Proximal3.566613.91876HepG2U2AF2
chr183957662739576696+CDS,intron-Proximal3.998595.79432HepG2BCLAF1
chr183955032839550424+CDS,intron-Proximal3.675934.25541HepG2GRWD1
chr183958432039584418+CDS4.045148.19556HepG2BCLAF1
chr183957042039570526+CDS,intron-Proximal4.026888.51432HepG2BCLAF1
chr183955036939550421+CDS,intron-Proximal4.258644.16554HepG2PPIG
chr183960928839609371+CDS,intron-Proximal3.817306.81385HepG2BCLAF1
chr183959345439593523+CDS3.531207.02567HepG2BCLAF1
chr183953760739537727+CDS,intron-Distal,intron-Proximal3.619485.99043HepG2GRWD1
chr183955035739550461+CDS,intron-Proximal3.287286.62505K562UCHL5
chr183960747539607518+CDS,intron-Proximal5.319366.58593HepG2BCLAF1
chr183958440639584504+CDS3.916525.80935K562ZNF622
chr183955029039550423+CDS,intron-Proximal3.346409.52893HepG2BCLAF1
chr183958445439584511+CDS,intron-Proximal4.127824.21087HepG2GRWD1
chr183960060139600667+CDS,intron-Proximal3.522244.74886HepG2BCLAF1
chr183958426539584344+CDS,intron-Proximal5.311916.40247K562SF3B4
chr183954247839542624+CDS,intron-Proximal3.704814.95675K562SRSF1
chr183954245339542574+CDS,intron-Proximal3.6602510.10467HepG2BCLAF1
chr183964742839647479+CDS,intron-Proximal3.554104.09885HepG2BCLAF1
chr183954245339542610+CDS,intron-Proximal3.568028.64848K562UCHL5
chr183955028839550369+CDS,intron-Proximal3.478933.86355HepG2PPIG
chr183958441839584516+CDS,intron-Proximal3.611848.66838HepG2BCLAF1
chr183958433939584406+CDS4.607365.59615K562ZNF622
chr183953528139535326+CDS,intron-Proximal3.593114.09885HepG2BCLAF1
chr183953753439537600+CDS,intron-Distal,intron-Proximal3.113903.55800HepG2BCLAF1
chr183957589739575953+CDS3.826265.35703HepG2BCLAF1
chr183959340539593508+CDS,intron-Proximal4.144954.23295HepG2GRWD1
chr183955036739550444+CDS,intron-Proximal3.181236.73886K562ZNF622
chr183958434939584454+CDS3.533765.28199HepG2GRWD1
chr183953763239537727+CDS,intron-Distal,intron-Proximal3.310058.50351HepG2BCLAF1
chr183961379639613910+CDS4.215669.98400HepG2BCLAF1
chr183964265339642764+intron-Distal3.414544.23286HepG2QKI
chr183956267039562840+intron-Distal3.230423.07751K562KHSRP
chr183958457539584662+intron-Distal,intron-Proximal4.283404.85626K562TARDBP
chr183954365939543765+intron-Distal4.381265.91698K562KHSRP
chr183955354539553604+intron-Distal3.316623.73266K562KHSRP
chr183961903739619162+intron-Distal3.263504.54315HepG2HNRNPL
chr183956132139561446+intron-Distal4.302894.92751K562HLTF
chr183959760439597726+intron-Distal4.046344.31512K562KHSRP
chr183959952739599646+intron-Distal4.620983.62238HepG2MATR3
chr183955311139553265+intron-Distal3.141717.22304K562KHSRP
chr183962526439625370+intron-Distal3.964556.90077HepG2PTBP1
chr183962527639625366+intron-Distal4.573034.67693K562PTBP1
chr183955673239556868+intron-Distal4.192434.19590K562HLTF
chr183956105539561151+intron-Distal3.829426.83037K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PIK3C3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PIK3C3 is not available on ENCORE database.

  • 81 RBPs can affect the levels of PIK3C3.  








The Knockdown/knockout RNA-Seq assay for PIK3C3 is not available on ENCORE database.





81 RBPs can affect the gene expression of PIK3C3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PIK3C3ENSG00000078142.71096.004801279.67860-0.223502.214101.65750HepG2ACO1
PIK3C3ENSG00000078142.72322.050601863.701400.317101.919801.46730HepG2AKAP1
PIK3C3ENSG00000078142.71977.314901528.015000.371805.631804.71160HepG2AUH
PIK3C3ENSG00000078142.71281.74600892.134300.522705.371804.57190HepG2BOP1
PIK3C3ENSG00000078142.71264.20680869.161600.540402.828202.05430HepG2CNOT7
PIK3C3ENSG00000078142.71358.956801634.03190-0.265903.850202.99930HepG2DAZAP1
PIK3C3ENSG00000078142.7717.774201233.85960-0.7816011.021809.77250HepG2DDX21
PIK3C3ENSG00000078142.71228.595001533.50140-0.319801.831701.31840HepG2DDX6
PIK3C3ENSG00000078142.7754.245201049.56240-0.476707.574106.56760HepG2DNAJC2
PIK3C3ENSG00000078142.71157.167301474.34100-0.349502.373801.82230HepG2EIF2S1
PIK3C3ENSG00000078142.7742.31460954.98340-0.363402.988201.76690HepG2EIF2S2
PIK3C3ENSG00000078142.7912.503901165.02980-0.352503.123101.97980HepG2EIF3G
PIK3C3ENSG00000078142.71095.852001629.39210-0.572304.747603.91360HepG2EIF4A3
PIK3C3ENSG00000078142.7948.122001586.30440-0.742506.159405.16320HepG2EIF4B
PIK3C3ENSG00000078142.7816.749301250.58370-0.614607.856206.45530HepG2EWSR1
PIK3C3ENSG00000078142.7995.80880755.835500.397702.781301.50840HepG2FKBP4
PIK3C3ENSG00000078142.71051.101701439.46660-0.453602.623301.53590HepG2FUS
PIK3C3ENSG00000078142.71163.691001643.77040-0.498304.408303.54940HepG2FXR1
PIK3C3ENSG00000078142.7652.588201069.12620-0.712208.641007.59360HepG2HNRNPA1
PIK3C3ENSG00000078142.7433.962701189.18260-1.4543030.0452028.05060HepG2HNRNPC
PIK3C3ENSG00000078142.71118.634801543.88520-0.464804.278503.42560HepG2HNRNPK
PIK3C3ENSG00000078142.7523.25040877.05840-0.745209.389207.81590HepG2HNRNPM
PIK3C3ENSG00000078142.7547.054201181.32210-1.1106030.9563029.11300HepG2HNRNPU
PIK3C3ENSG00000078142.71229.936801550.12190-0.333802.289501.66860HepG2IGF2BP2
PIK3C3ENSG00000078142.7997.712101206.68530-0.274403.598202.77210HepG2ILF2
PIK3C3ENSG00000078142.7969.818001169.86310-0.270603.105702.02720HepG2KIF1C
PIK3C3ENSG00000078142.71167.253101712.01680-0.552604.032103.02610HepG2LARP4
PIK3C3ENSG00000078142.7939.861101189.44670-0.339802.358701.31590HepG2LARP7
PIK3C3ENSG00000078142.7975.771701644.34330-0.752908.779307.62350HepG2MAGOH
PIK3C3ENSG00000078142.71120.092801653.58200-0.562004.791803.97890HepG2MATR3
PIK3C3ENSG00000078142.7882.594201692.56190-0.9394012.6663011.36660HepG2NCBP2
PIK3C3ENSG00000078142.71249.611801597.29890-0.354204.802104.03760HepG2PCBP1
PIK3C3ENSG00000078142.71032.18970835.689600.304602.952702.15670HepG2PRPF4
PIK3C3ENSG00000078142.7987.852301625.33720-0.7184016.5117015.39000HepG2PTBP1
PIK3C3ENSG00000078142.71175.769801546.66670-0.395602.931302.32070HepG2PUF60
PIK3C3ENSG00000078142.71460.941001641.80160-0.168401.901401.38950HepG2PUM1
PIK3C3ENSG00000078142.7894.417101303.45360-0.5433010.090309.03930HepG2PUS1
PIK3C3ENSG00000078142.71317.059401760.22530-0.418405.301404.47760HepG2QKI
PIK3C3ENSG00000078142.71825.318701466.286700.315903.679103.10390HepG2RBM22
PIK3C3ENSG00000078142.71191.242801597.53840-0.423404.466803.62670HepG2RBM25
PIK3C3ENSG00000078142.71026.167001434.25420-0.483003.875602.68760HepG2RBM27
PIK3C3ENSG00000078142.7831.027801164.67530-0.487003.767902.52950HepG2RCC2
PIK3C3ENSG00000078142.71176.035001808.82280-0.6211012.8841011.87580HepG2NELFE
PIK3C3ENSG00000078142.71204.678801684.71150-0.483908.290207.30780HepG2RECQL
PIK3C3ENSG00000078142.7936.930101322.80710-0.497604.240403.25790HepG2RPS2
PIK3C3ENSG00000078142.7998.473101350.25090-0.435403.343102.15930HepG2RPS5
PIK3C3ENSG00000078142.7872.421101052.03290-0.270102.716702.07670HepG2SAFB2
PIK3C3ENSG00000078142.71289.17040877.071700.555605.826604.83570HepG2SF3B1
PIK3C3ENSG00000078142.71352.919301692.13950-0.322804.112303.41490HepG2SF3B4
PIK3C3ENSG00000078142.7848.447401226.87060-0.5321010.435209.31670HepG2SMN1
PIK3C3ENSG00000078142.72667.239201656.139400.6874022.1592021.09450HepG2SRFBP1
PIK3C3ENSG00000078142.71466.222801766.24620-0.268603.189902.69170HepG2SRSF1
PIK3C3ENSG00000078142.71334.669701527.04410-0.194301.896701.36500HepG2SRSF5
PIK3C3ENSG00000078142.71224.791601736.72460-0.503808.692207.69280HepG2SUCLG1
PIK3C3ENSG00000078142.71189.203101587.62330-0.416905.471804.72890HepG2TAF15
PIK3C3ENSG00000078142.7968.417501458.75400-0.591008.171406.74680HepG2TIA1
PIK3C3ENSG00000078142.7832.462701147.95990-0.463605.137704.49990HepG2TIAL1
PIK3C3ENSG00000078142.7925.206701320.37780-0.513103.049301.50590HepG2TRA2A
PIK3C3ENSG00000078142.7975.119501158.13090-0.248102.383001.85190HepG2TRIM56
PIK3C3ENSG00000078142.71200.068601510.94070-0.332303.088402.16020HepG2TUFM
PIK3C3ENSG00000078142.7378.06640534.04760-0.498302.863002.09140HepG2UCHL5
PIK3C3ENSG00000078142.7993.984701368.64030-0.461407.580006.51770HepG2UPF1
PIK3C3ENSG00000078142.7837.542201321.37290-0.6578012.8447011.69530HepG2UTP3
PIK3C3ENSG00000078142.71008.032901446.19430-0.520703.323702.15930HepG2XRCC6
PIK3C3ENSG00000078142.7664.57500889.86490-0.421202.306101.63860HepG2XRN2
PIK3C3ENSG00000078142.7984.62360824.715600.255602.423801.78880HepG2ZC3H8
PIK3C3ENSG00000078142.71494.838101911.99420-0.355103.379902.00490K562APOBEC3C
PIK3C3ENSG00000078142.7766.296101089.03990-0.507105.419404.32940K562CPSF6
PIK3C3ENSG00000078142.72114.633702664.45190-0.333403.953102.77740K562CELF1
PIK3C3ENSG00000078142.7789.258701007.39140-0.352103.345602.01090K562DDX21
PIK3C3ENSG00000078142.7853.748501106.80580-0.374504.093903.24480K562EIF2S2
PIK3C3ENSG00000078142.7651.75750911.77060-0.484304.647703.62780K562EIF3G
PIK3C3ENSG00000078142.71649.126502166.87630-0.393905.631404.31350K562EIF4G2
PIK3C3ENSG00000078142.7833.104301108.03770-0.411403.239302.30830K562FMR1
PIK3C3ENSG00000078142.7823.902501039.77930-0.335702.454501.70430K562GPKOW
PIK3C3ENSG00000078142.7319.14120884.26450-1.4703028.2144026.38700K562HNRNPC
PIK3C3ENSG00000078142.7949.870201233.55660-0.377003.982802.90400K562HNRNPU
PIK3C3ENSG00000078142.7626.358401014.93460-0.696308.412006.83240K562METAP2
PIK3C3ENSG00000078142.7574.92460780.45870-0.440902.711401.43740K562NONO
PIK3C3ENSG00000078142.7934.544901114.92490-0.254602.732501.98970K562NSUN2
PIK3C3ENSG00000078142.71677.178402226.53840-0.408805.075803.21300K562PNPT1
PIK3C3ENSG00000078142.7587.68900792.82900-0.432003.066502.10910K562PSIP1
PIK3C3ENSG00000078142.71822.358502364.21040-0.375603.668802.73190K562PUF60
PIK3C3ENSG00000078142.72075.185002514.81630-0.277202.973101.86270K562PUM1
PIK3C3ENSG00000078142.71982.645902463.91220-0.313504.070602.89940K562PUM2
PIK3C3ENSG00000078142.71747.286101177.050300.569806.323005.54060K562PUS1
PIK3C3ENSG00000078142.7928.272401379.57500-0.571603.216901.55850K562SBDS
PIK3C3ENSG00000078142.7888.008601154.42820-0.378502.513001.51930K562SRSF5
PIK3C3ENSG00000078142.7910.913301237.30040-0.441803.701502.87880K562TARDBP
PIK3C3ENSG00000078142.7880.493401193.49340-0.438804.356003.29360K562TIA1
PIK3C3ENSG00000078142.7637.88110810.09840-0.344802.236301.39890K562TRIM56
PIK3C3ENSG00000078142.7978.003801182.18350-0.273502.682701.97480K562UPF1
PIK3C3ENSG00000078142.7877.617701051.94980-0.261402.534901.72200K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PIK3C3 is not available on ENCORE database.





6 RBPs can affect the splicing of PIK3C3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPIK3C3ENSG00000078142.7chr18+396137893961392139609288396094053961765539617781-0.137000.000000.00001excludedHepG2U2AF2
SEPIK3C3ENSG00000078142.7chr18+396378463963801539629494396295693964470339644794-0.266000.000300.00437excludedK562AQR
SEPIK3C3ENSG00000078142.7chr18+396137893961392139609288396094053961765539617781-0.074000.006290.05622excludedK562AQR
SEPIK3C3ENSG00000078142.7chr18+396206403962070539618744396188143962369639623781-0.162000.000260.00391excludedK562AQR
SEPIK3C3ENSG00000078142.7chr18+3956490839565071395502903955042039567775395678390.185000.000000.00036includedK562LARP4
SEPIK3C3ENSG00000078142.7chr18+3956490839565071395502903955042039567775395678390.166000.000050.01859includedK562SBDS
SEPIK3C3ENSG00000078142.7chr18+3956490839565071395502903955042039567775395678390.163000.000000.00067includedK562HNRNPUL1
SEPIK3C3ENSG00000078142.7chr18+395375343953772339535220395353243954245339542597-0.055000.000280.01397excludedK562TARDBP
A3SSPIK3C3ENSG00000078142.7chr18+3964464739644794396447033964479439637846396380150.069000.015730.07782longerK562AQR
A3SSPIK3C3ENSG00000078142.7chr18+3962062139620705396206403962070539618744396188140.160000.000370.00285longerK562AQR
A3SSPIK3C3ENSG00000078142.7chr18+3957582039575958395758533957595839573233395733050.066000.000410.00311longerK562AQR
A5SSPIK3C3ENSG00000078142.7chr18+3961765539617886396176553961778439618744396188140.228000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PIK3C3 is not avaliable on ENCORE database.