PDCD2

General Information

Gene Name       : PDCD2
Gene ID             : ENSG00000071994.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PDCD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PDCD2ENSG00000071994.1073.2666.3569.81ENCSR000AEF
HepG2PDCD2ENSG00000071994.1063.3793.7178.54ENCSR985KAT
K562PDCD2ENSG00000071994.10200.19213.66206.93ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PDCD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PDCD2 RNA is bound by 17 proteins.  







eCLIP assay for PDCD2 is not avaliable on ENCORE database.





17 proteins are bound to PDCD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6170886557170886610-3'-UTR,intron-Distal,intron-Proximal3.536249.93746K562YBX3
chr6170890702170890823-3'-UTR,intron-Distal,intron-Proximal4.965979.00511HepG2CSTF2
chr6170886785170886792-3'-UTR,CDS,intron-Distal3.454336.18351K562YBX3
chr6170886743170886747-3'-UTR,CDS,intron-Distal3.6521117.84906K562YBX3
chr6170891182170891236-3'-UTR,intron-Distal3.659696.54748K562PABPC4
chr6170892544170892594-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.239115.47926K562AQR
chr6170887708170887757-3'-UTR,CDS,intron-Distal4.777345.95026HepG2U2AF2
chr6170887953170887991-3'-UTR,CDS,intron-Distal,intron-Proximal3.262906.22806K562PABPC4
chr6170886304170886422-3'-UTR,intron-Distal4.0843420.03168K562PUM2
chr6170886775170886785-3'-UTR,CDS,intron-Distal3.8988019.47013K562YBX3
chr6170886274170886346-3'-UTR,intron-Distal5.329636.73016HepG2SUB1
chr6170887504170887583-3'-UTR,intron-Distal,intron-Proximal,polyA_site3.032543.11628K562KHSRP
chr6170886305170886355-3'-UTR,intron-Distal4.7755113.44822K562PABPC4
chr6170886467170886539-3'-UTR,intron-Distal,intron-Proximal5.419927.71888HepG2SUB1
chr6170888002170888059-3'-UTR,CDS,intron-Distal,intron-Proximal4.7404917.58217K562LIN28B
chr6170892268170892339-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.009054.62757K562SF3B4
chr6170891166170891260-3'-UTR,intron-Distal3.789573.47315HepG2CSTF2
chr6170886754170886774-3'-UTR,CDS,intron-Distal3.7916519.52640K562YBX3
chr6170886268170886341-3'-UTR,intron-Distal3.535409.09662K562YBX3
chr6170886747170886754-3'-UTR,CDS,intron-Distal3.6220517.08567K562YBX3
chr6170886355170886425-3'-UTR,intron-Distal,intron-Proximal4.0538214.90696K562PABPC4
chr6170893642170893711-5'-UTR,CDS,intron-Distal,intron-Proximal3.189674.07582K562GEMIN5
chr6170893649170893715-5'-UTR,CDS,intron-Distal,intron-Proximal4.4700418.84037K562DDX3X
chr6170892749170892810-5'-UTR,CDS,intron-Distal,intron-Proximal4.087783.01090HepG2CDC40
chr6170893616170893711-5'-UTR,CDS,intron-Distal,intron-Proximal5.3733152.74924HepG2DDX3X
chr6170893653170893710-5'-UTR,CDS,intron-Distal,intron-Proximal4.221035.97538K562DHX30
chr6170893538170893642-CDS,intron-Distal,intron-Proximal3.9531712.40707K562GEMIN5
chr6170893337170893412-CDS,intron-Distal,intron-Proximal3.6364913.01942HepG2PRPF8
chr6170893529170893624-CDS,intron-Distal,intron-Proximal3.1979113.40198K562DHX30
chr6170893514170893616-CDS,intron-Distal,intron-Proximal3.9686627.04041HepG2DDX3X
chr6170893460170893514-CDS,intron-Distal,intron-Proximal3.266836.72797HepG2DDX3X
chr6170893445170893518-CDS,intron-Distal,intron-Proximal4.265975.00225K562GEMIN5
chr6170893492170893576-CDS,intron-Distal,intron-Proximal4.237505.13929K562PCBP1
chr6170893527170893649-CDS,intron-Distal,intron-Proximal4.0709226.98506K562DDX3X
chr6170893377170893387-intron-Distal,intron-Proximal5.0053518.60307K562AQR
chr6170893349170893377-intron-Distal,intron-Proximal5.7259121.81762K562AQR
chr6170893329170893349-intron-Distal,intron-Proximal5.6807921.23371K562AQR
chr6170892523170892567-intron-Distal,intron-Proximal5.101976.98483K562RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PDCD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PDCD2 is not available on ENCORE database.

  • 86 RBPs can affect the levels of PDCD2.  








The Knockdown/knockout RNA-Seq assay for PDCD2 is not available on ENCORE database.





86 RBPs can affect the gene expression of PDCD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PDCD2ENSG00000071994.62500.699501789.700000.482503.873303.25950HepG2AKAP1
PDCD2ENSG00000071994.61462.056102018.91540-0.465608.476807.38480HepG2AUH
PDCD2ENSG00000071994.6702.535501008.46280-0.521503.930702.87700HepG2BCLAF1
PDCD2ENSG00000071994.61038.544901670.04870-0.685305.924104.47060HepG2CCAR1
PDCD2ENSG00000071994.61365.203301128.201700.275003.402702.67900HepG2CKAP4
PDCD2ENSG00000071994.6878.339801297.79450-0.563203.170902.34910HepG2CNOT7
PDCD2ENSG00000071994.6754.123001243.90520-0.722008.527207.37670HepG2CPSF6
PDCD2ENSG00000071994.61480.838701875.44150-0.340805.879304.85550HepG2DAZAP1
PDCD2ENSG00000071994.61239.274801043.690300.247702.707301.88200HepG2DDX19B
PDCD2ENSG00000071994.6796.451001141.11510-0.518803.731802.84920HepG2DDX55
PDCD2ENSG00000071994.61034.870001472.59240-0.508903.832903.11600HepG2DDX6
PDCD2ENSG00000071994.6870.404401064.94230-0.291002.617601.92900HepG2DNAJC21
PDCD2ENSG00000071994.6885.351901055.51570-0.253602.637801.99900HepG2DNAJC2
PDCD2ENSG00000071994.6939.092901415.81110-0.592305.566504.74290HepG2EIF2S1
PDCD2ENSG00000071994.6997.428001564.72100-0.649605.964605.02870HepG2EIF4A3
PDCD2ENSG00000071994.6807.217101523.31650-0.916208.805207.61410HepG2EIF4B
PDCD2ENSG00000071994.61254.634401772.40470-0.498405.178404.08410HepG2EIF4G2
PDCD2ENSG00000071994.61071.893401464.40970-0.450203.349402.62200HepG2G3BP1
PDCD2ENSG00000071994.6866.477901410.10700-0.702607.064706.07320HepG2GPKOW
PDCD2ENSG00000071994.6955.067901195.89190-0.324402.348801.70490HepG2HNRNPC
PDCD2ENSG00000071994.61276.681901545.18800-0.275402.820002.09530HepG2HNRNPF
PDCD2ENSG00000071994.61205.11990940.921000.356903.092402.08850HepG2HNRNPM
PDCD2ENSG00000071994.61247.221001521.57890-0.286902.303901.64150HepG2IGF2BP1
PDCD2ENSG00000071994.61129.768201488.58760-0.397902.918102.22810HepG2IGF2BP2
PDCD2ENSG00000071994.61125.471201579.03570-0.488504.097403.30150HepG2MAGOH
PDCD2ENSG00000071994.61358.769501103.728300.299802.393701.63790HepG2MSI2
PDCD2ENSG00000071994.6709.991201047.86120-0.561602.487101.45580HepG2NONO
PDCD2ENSG00000071994.6961.191901193.17740-0.311901.967601.33190HepG2NSUN2
PDCD2ENSG00000071994.61040.922801447.63520-0.475803.831402.99310HepG2PABPC4
PDCD2ENSG00000071994.61170.032701473.70080-0.332903.788503.17080HepG2PTBP1
PDCD2ENSG00000071994.61108.146601775.22850-0.6799010.199609.15350HepG2PUF60
PDCD2ENSG00000071994.6923.474001149.46860-0.315803.695503.00520HepG2PUS1
PDCD2ENSG00000071994.61170.380101596.07740-0.447605.808604.95110HepG2QKI
PDCD2ENSG00000071994.61861.694301130.220300.719904.528503.63840HepG2RAVER1
PDCD2ENSG00000071994.61489.825101937.42390-0.379005.090804.44220HepG2RBM22
PDCD2ENSG00000071994.61186.083501448.53410-0.288402.325601.70200HepG2RBM25
PDCD2ENSG00000071994.6993.986401302.33310-0.389802.126901.42470HepG2RPS3A
PDCD2ENSG00000071994.61359.054401702.16210-0.324804.986204.08720HepG2SLBP
PDCD2ENSG00000071994.61071.400001433.15400-0.419702.551401.59370HepG2SRSF3
PDCD2ENSG00000071994.61450.176601899.89150-0.389706.505505.78090HepG2SSB
PDCD2ENSG00000071994.6711.47210920.86850-0.372202.839601.88690HepG2SUPT6H
PDCD2ENSG00000071994.6781.923601135.95660-0.538804.074103.27710HepG2SUPV3L1
PDCD2ENSG00000071994.6932.958301154.37860-0.307202.591902.10530HepG2TIAL1
PDCD2ENSG00000071994.6995.150601164.66750-0.226902.038801.54060HepG2TRIM56
PDCD2ENSG00000071994.61405.999701734.31890-0.302802.643601.79060HepG2TUFM
PDCD2ENSG00000071994.6906.08610671.040500.433103.058102.26190HepG2UCHL5
PDCD2ENSG00000071994.6721.585201129.56730-0.6465011.9071010.64230HepG2UPF1
PDCD2ENSG00000071994.61390.018101090.556100.349904.414803.68690HepG2UTP3
PDCD2ENSG00000071994.61022.431301242.31080-0.281003.492802.89830HepG2ZNF622
PDCD2ENSG00000071994.64644.578106558.81430-0.497904.279203.57980K562AQR
PDCD2ENSG00000071994.63506.462704219.95950-0.267203.681702.12200K562BCCIP
PDCD2ENSG00000071994.63414.367004078.03240-0.256304.236903.03240K562BCLAF1
PDCD2ENSG00000071994.62610.810403404.33030-0.382903.606302.61180K562BOP1
PDCD2ENSG00000071994.63933.075705589.54240-0.507102.789901.72240K562CNOT7
PDCD2ENSG00000071994.62533.123603619.71220-0.515008.265106.89740K562CPSF6
PDCD2ENSG00000071994.62570.424403093.79540-0.267403.097101.97260K562CSTF2
PDCD2ENSG00000071994.67767.841705647.513800.459808.381007.32710K562DDX47
PDCD2ENSG00000071994.64965.436804024.606300.303003.006902.08710K562DKC1
PDCD2ENSG00000071994.62502.725103470.67840-0.471703.260401.86110K562EEF2
PDCD2ENSG00000071994.62322.479103353.55000-0.530006.190604.77950K562EFTUD2
PDCD2ENSG00000071994.63701.954405392.95930-0.5428013.6059012.19810K562EIF2S2
PDCD2ENSG00000071994.63469.998002855.092400.281303.483502.59640K562EIF3G
PDCD2ENSG00000071994.62024.569902633.29630-0.379303.922502.94750K562EIF4A3
PDCD2ENSG00000071994.61772.159502371.33250-0.420205.444203.74260K562EIF4B
PDCD2ENSG00000071994.61879.985202298.53730-0.290003.310601.87100K562EWSR1
PDCD2ENSG00000071994.62590.134703683.10230-0.507906.239404.93970K562FMR1
PDCD2ENSG00000071994.62315.520903121.81830-0.431003.973602.86290K562FTO
PDCD2ENSG00000071994.64330.387302738.500500.6610018.7733017.30790K562FXR1
PDCD2ENSG00000071994.62520.433903455.88020-0.455405.677504.54450K562GPKOW
PDCD2ENSG00000071994.62412.140203483.30380-0.530108.213807.23430K562HNRNPC
PDCD2ENSG00000071994.65376.999903896.320200.464604.371803.18450K562HNRNPM
PDCD2ENSG00000071994.62796.860803533.13280-0.337102.801701.34040K562LIN28B
PDCD2ENSG00000071994.62495.357203373.34760-0.434905.568904.30010K562METAP2
PDCD2ENSG00000071994.62892.572303714.18430-0.360702.866602.01910K562PCBP3
PDCD2ENSG00000071994.62230.339202848.92780-0.353204.207203.21730K562POLR2G
PDCD2ENSG00000071994.62245.351503123.18210-0.476106.182104.75250K562PSIP1
PDCD2ENSG00000071994.67081.692808599.01480-0.280104.010902.85140K562PUM2
PDCD2ENSG00000071994.62617.716803209.37060-0.294003.365401.36950K562QKI
PDCD2ENSG00000071994.62407.779502849.66900-0.243102.341601.43340K562RCC2
PDCD2ENSG00000071994.62318.807302912.43130-0.328803.176101.35040K562RECQL
PDCD2ENSG00000071994.63051.464302538.395100.265502.335501.34740K562SAFB
PDCD2ENSG00000071994.62622.763003286.86200-0.325602.276801.40410K562SF3B1
PDCD2ENSG00000071994.61834.283302701.39250-0.558507.574505.63410K562SRFBP1
PDCD2ENSG00000071994.63987.399704621.98030-0.213102.797601.85790K562SRPK2
PDCD2ENSG00000071994.62979.804203524.82890-0.242302.173801.53880K562SRSF1
PDCD2ENSG00000071994.62545.302703328.61000-0.387103.874102.59460K562SRSF5
PDCD2ENSG00000071994.62027.307003160.08170-0.640406.423104.82790K562SUPV3L1
PDCD2ENSG00000071994.63581.273602857.518700.325603.948702.96560K562SYNCRIP
PDCD2ENSG00000071994.62605.559503567.64000-0.453404.797603.85560K562TARDBP
PDCD2ENSG00000071994.62470.444103441.31730-0.478207.126005.71310K562TIA1
PDCD2ENSG00000071994.62286.991003003.95820-0.393403.375902.33760K562TIAL1
PDCD2ENSG00000071994.62726.649303376.28510-0.308302.703101.62660K562TRA2A
PDCD2ENSG00000071994.62486.863103191.50690-0.359903.467402.38730K562TRIM56
PDCD2ENSG00000071994.62432.939602871.18330-0.238902.247701.52440K562U2AF2
PDCD2ENSG00000071994.62508.085003344.34590-0.415103.846702.62730K562UCHL5
PDCD2ENSG00000071994.63423.399004848.17560-0.5020011.183809.86000K562UPF1
PDCD2ENSG00000071994.63083.331704148.46440-0.428104.454303.33130K562WDR3
PDCD2ENSG00000071994.64881.830504313.690300.178402.520301.71000K562WDR43
PDCD2ENSG00000071994.62692.317103405.14540-0.338902.665601.48670K562XRN2
PDCD2ENSG00000071994.65783.248107389.60370-0.353602.583001.75510K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PDCD2 is not available on ENCORE database.





6 RBPs can affect the splicing of PDCD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPDCD2ENSG00000071994.6chr6-170887944170888058170886523170886805170892144170892276-0.233000.006570.06585excludedHepG2U2AF2
SEPDCD2ENSG00000071994.6chr6-1708890891708891931708879441708880581708921441708922760.062000.003130.06216includedHepG2SRSF1
SEPDCD2ENSG00000071994.6chr6-170889089170889193170887944170888058170892144170892276-0.101000.000790.05724excludedHepG2TIAL1
SEPDCD2ENSG00000071994.6chr6-1708890891708891931708879441708880581708921441708922760.080000.000490.03610includedHepG2SRSF9
A3SSPDCD2ENSG00000071994.6chr6-1708875691708877841708875691708877441708879441708880580.140000.000000.00001longerK562AQR
MXEPDCD2ENSG00000071994.6chr6-1708890891708891931708921441708922761708879441708880581708925921708928350.059000.001700.098501includedK562HNRNPL

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PDCD2 is not avaliable on ENCORE database.