NBN

General Information

Gene Name       : NBN
Gene ID             : ENSG00000104320.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NBN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NBNENSG00000104320.1351.7739.1745.47ENCSR000AEF
HepG2NBNENSG00000104320.139.1721.9115.54ENCSR985KAT
K562NBNENSG00000104320.1327.1729.9428.55ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NBN is not avaliable on ENCORE database.



Proteins bound to RNA
  • NBN RNA is bound by 14 proteins.  







eCLIP assay for NBN is not avaliable on ENCORE database.





14 proteins are bound to NBN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr89094577590945831-3'-UTR,intron-Distal4.775763.27332K562DDX6
chr89096575990965886-3'-UTR,CDS,intron-Distal3.395938.76551K562ZNF622
chr89094583190945875-3'-UTR,intron-Distal4.205343.35973HepG2FUBP3
chr89094714190947203-3'-UTR,intron-Distal3.378083.67697K562YBX3
chr89094722190947280-3'-UTR,intron-Distal3.343594.46957K562TIA1
chr89096760490967655-3'-UTR,CDS,intron-Distal3.238524.91034K562YBX3
chr89094681290946906-3'-UTR,intron-Distal3.712047.08510K562FAM120A
chr89094665290946712-3'-UTR,intron-Distal3.846467.06377K562YBX3
chr89094580490945881-3'-UTR,intron-Distal5.058414.23616K562CPEB4
chr89099296290993097-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.254077.95223HepG2BCLAF1
chr89099675590996860-5'-UTR,CDS,intron-Distal,intron-Proximal3.324807.98234K562DDX3X
chr89099494990995026-5'-UTR,CDS,intron-Distal,intron-Proximal3.236296.20049K562YBX3
chr89098271390982749-5'-UTR,CDS,intron-Distal,intron-Proximal3.920635.96588K562ZNF622
chr89098259690982703-5'-UTR,CDS,intron-Distal,intron-Proximal3.7227410.62851K562UCHL5
chr89098264990982706-5'-UTR,CDS,intron-Distal,intron-Proximal4.377103.71570HepG2BCLAF1
chr89098274990982786-5'-UTR,CDS,intron-Distal,intron-Proximal3.481174.44630K562ZNF622
chr89098260790982713-5'-UTR,CDS,intron-Distal,intron-Proximal3.501219.28987K562ZNF622
chr89099663890996715-intron-Distal,intron-Proximal3.153345.47630K562TIA1
chr89099313590993184-intron-Distal,intron-Proximal4.811915.40008K562SF3B4
chr89095139290951458-intron-Distal4.368884.74221HepG2PTBP1
chr89099673390996753-intron-Distal,intron-Proximal4.234823.11721K562AQR
chr89095138490951464-intron-Distal3.550835.02233K562PTBP1
chr89099029190990375-intron-Distal,intron-Proximal3.689603.06150K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NBN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NBN is not available on ENCORE database.

  • 95 RBPs can affect the levels of NBN.  








The Knockdown/knockout RNA-Seq assay for NBN is not available on ENCORE database.





95 RBPs can affect the gene expression of NBN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NBNENSG00000104320.91406.41900865.089300.701006.450005.67530HepG2AKAP1
NBNENSG00000104320.91013.452001263.84880-0.318503.555002.79400HepG2AUH
NBNENSG00000104320.9579.88120843.67240-0.540903.366402.33420HepG2BCCIP
NBNENSG00000104320.9656.62990962.95870-0.552405.216304.42640HepG2BOP1
NBNENSG00000104320.9772.053501103.65580-0.515502.195601.33610HepG2CCAR1
NBNENSG00000104320.9392.22170884.03320-1.1724016.6065015.08820HepG2CPSF6
NBNENSG00000104320.9758.315701066.99740-0.492707.885606.73010HepG2DAZAP1
NBNENSG00000104320.9680.289701003.88980-0.561402.733101.76120HepG2DDX59
NBNENSG00000104320.9425.25050711.78360-0.743105.638304.78400HepG2DDX6
NBNENSG00000104320.9447.60130605.65980-0.436302.989001.97470HepG2DHX30
NBNENSG00000104320.9373.63550622.46480-0.7364010.994609.79230HepG2DNAJC2
NBNENSG00000104320.9679.54380498.462400.447002.602201.70530HepG2EEF2
NBNENSG00000104320.9422.82700684.37720-0.694705.507204.68690HepG2EIF2S1
NBNENSG00000104320.9540.49230736.32560-0.446102.131401.52500HepG2EIF4B
NBNENSG00000104320.91139.602701451.04660-0.348604.035103.33290HepG2ETF1
NBNENSG00000104320.9376.90960707.86360-0.909308.838207.68440HepG2G3BP1
NBNENSG00000104320.9655.916501002.07860-0.611405.062904.21340HepG2GPKOW
NBNENSG00000104320.9485.18420633.95090-0.385802.434701.82620HepG2HNRNPA1
NBNENSG00000104320.9424.94250705.17820-0.730705.461404.51430HepG2HNRNPC
NBNENSG00000104320.9526.92620900.84870-0.7737012.5987011.21660HepG2HNRNPF
NBNENSG00000104320.9490.89690971.94840-0.9855023.7756022.00120HepG2HNRNPL
NBNENSG00000104320.9560.73900956.30580-0.770108.115107.10010HepG2HNRNPLL
NBNENSG00000104320.9560.65500887.08880-0.662007.644406.49640HepG2IGF2BP1
NBNENSG00000104320.9464.26480715.54770-0.624109.059007.80930HepG2ILF2
NBNENSG00000104320.9496.84490648.87820-0.385203.773202.58390HepG2KIF1C
NBNENSG00000104320.9632.66580418.545100.596003.417702.02520HepG2KRR1
NBNENSG00000104320.9996.38420763.238600.384502.465501.84600HepG2MAGOH
NBNENSG00000104320.9492.83690767.53950-0.639104.093603.34070HepG2MATR3
NBNENSG00000104320.9777.173701058.03330-0.445104.807603.80360HepG2NOL12
NBNENSG00000104320.9515.02780699.77510-0.442202.699901.98590HepG2PABPC4
NBNENSG00000104320.9903.35770683.329800.402604.285203.55900HepG2PCBP1
NBNENSG00000104320.9466.51100624.79830-0.421503.562002.73620HepG2PPIL4
NBNENSG00000104320.9427.18180600.32690-0.490904.737403.75470HepG2PRPF4
NBNENSG00000104320.9920.54440695.292300.404804.438603.78100HepG2PTBP1
NBNENSG00000104320.9795.377801009.98950-0.344602.572901.99570HepG2PUF60
NBNENSG00000104320.91463.112001072.153200.448408.486007.56650HepG2PUM1
NBNENSG00000104320.91008.995601212.81080-0.265402.220501.74270HepG2RBM22
NBNENSG00000104320.9988.70090773.811300.353503.313402.73240HepG2NELFE
NBNENSG00000104320.9600.58590970.28450-0.692007.537306.49240HepG2RPLP0
NBNENSG00000104320.9499.12080308.700600.693104.122203.14610HepG2RPS3A
NBNENSG00000104320.9490.06700623.82410-0.348202.913702.25680HepG2SAFB2
NBNENSG00000104320.9729.990301053.18890-0.528802.883302.08470HepG2SNRNP70
NBNENSG00000104320.91037.228801369.83290-0.401305.744905.09610HepG2SRFBP1
NBNENSG00000104320.91799.61970755.607701.2519046.0327044.61320HepG2SRSF1
NBNENSG00000104320.9592.90840885.01940-0.577906.859705.84480HepG2SRSF7
NBNENSG00000104320.9496.10450614.71370-0.309302.481501.95240HepG2SRSF9
NBNENSG00000104320.91439.659901134.112600.344104.888304.10310HepG2SUCLG1
NBNENSG00000104320.9600.82290422.547700.507702.729801.41410HepG2SUGP2
NBNENSG00000104320.9611.57810825.76680-0.433202.418801.78110HepG2SUPV3L1
NBNENSG00000104320.9414.61400679.12650-0.711909.058608.13940HepG2TAF15
NBNENSG00000104320.9312.07500932.21350-1.5788029.3939027.51340HepG2TARDBP
NBNENSG00000104320.9422.67140680.58660-0.687207.159206.42340HepG2TIAL1
NBNENSG00000104320.9389.11640686.77120-0.8196013.0077011.91160HepG2TRIM56
NBNENSG00000104320.91025.39190665.680100.623204.574603.77700HepG2U2AF1
NBNENSG00000104320.9243.41120487.81880-1.002909.426808.02840HepG2UCHL5
NBNENSG00000104320.9396.29400756.19930-0.932206.465404.88510HepG2UPF2
NBNENSG00000104320.9869.13320713.465800.284602.295001.73850HepG2UTP3
NBNENSG00000104320.9523.97350812.87620-0.633504.916403.95850HepG2XRN2
NBNENSG00000104320.9441.68430592.46460-0.423703.967003.18680HepG2ZC3H8
NBNENSG00000104320.92832.085202330.548900.281104.270403.59190K562AGGF1
NBNENSG00000104320.92044.932003117.38680-0.608308.608207.66580K562AQR
NBNENSG00000104320.93098.750602544.466400.284203.608702.55330K562ATP5C1
NBNENSG00000104320.91314.961801722.69250-0.389604.010003.06720K562CPSF6
NBNENSG00000104320.91059.596801341.93700-0.340803.071801.95330K562CSTF2
NBNENSG00000104320.95786.523704457.236900.376405.814404.40240K562CELF1
NBNENSG00000104320.93188.311402766.639100.204602.538401.91050K562DDX47
NBNENSG00000104320.93031.930002609.494200.216402.420201.60860K562DKC1
NBNENSG00000104320.91193.559501519.33850-0.348202.119701.31980K562EFTUD2
NBNENSG00000104320.91988.716702344.39900-0.237402.323001.65550K562EIF2S2
NBNENSG00000104320.91130.664201712.87460-0.599206.041804.21940K562EIF4B
NBNENSG00000104320.94371.755903625.082800.270103.990302.86510K562EIF4G2
NBNENSG00000104320.91561.444702138.95310-0.454004.785703.64930K562FIP1L1
NBNENSG00000104320.91319.175101752.83110-0.410103.695102.70270K562FMR1
NBNENSG00000104320.93171.197601971.078100.685904.680803.70720K562G3BP2
NBNENSG00000104320.91192.571001644.73400-0.463804.885203.83290K562GPKOW
NBNENSG00000104320.92555.242603124.36920-0.290102.143201.47250K562GRSF1
NBNENSG00000104320.9955.607201440.76720-0.592307.545306.60610K562HNRNPC
NBNENSG00000104320.91885.456002500.32920-0.407204.688603.27220K562HNRNPL
NBNENSG00000104320.91849.189602351.23940-0.346502.217701.32810K562IGF2BP2
NBNENSG00000104320.93267.911702573.563900.344503.377402.45560K562KIF1C
NBNENSG00000104320.91766.190502467.37820-0.482304.133802.98860K562MATR3
NBNENSG00000104320.91173.786001605.44950-0.451804.804103.62970K562METAP2
NBNENSG00000104320.91914.691502150.14880-0.167302.125601.46270K562NSUN2
NBNENSG00000104320.91227.120801658.62450-0.434703.508002.57110K562PCBP3
NBNENSG00000104320.9902.231201272.22290-0.495805.967004.79460K562POLR2G
NBNENSG00000104320.91855.785602428.17750-0.387803.621402.66380K562PPIG
NBNENSG00000104320.9911.958301291.80410-0.502304.834103.59380K562PSIP1
NBNENSG00000104320.95159.320604206.959600.294303.545602.32790K562PUM1
NBNENSG00000104320.93522.733204122.05670-0.226702.611701.67870K562PUM2
NBNENSG00000104320.93508.322002404.947200.544706.696005.89380K562PUS1
NBNENSG00000104320.92867.972902343.286500.291403.575002.91480K562RBM15
NBNENSG00000104320.91300.705801713.57200-0.397702.325101.41700K562RPS3
NBNENSG00000104320.91417.769001133.577100.322602.639101.58390K562SAFB
NBNENSG00000104320.91658.821702121.75120-0.355104.612703.58260K562SF3A3
NBNENSG00000104320.91222.361601564.24910-0.355802.331401.44690K562SF3B1
NBNENSG00000104320.91507.693802050.10360-0.443405.828104.55500K562SF3B4
NBNENSG00000104320.9843.587001117.30680-0.405403.332802.18170K562SRFBP1
NBNENSG00000104320.91258.366401654.49720-0.394803.281302.11880K562SRSF4
NBNENSG00000104320.91025.722101431.87220-0.481303.030701.96530K562SUPV3L1
NBNENSG00000104320.91842.444001276.070900.529807.759506.37280K562SYNCRIP
NBNENSG00000104320.91764.059902383.14910-0.434002.995502.25980K562TARDBP
NBNENSG00000104320.91882.430802298.74290-0.288202.005801.31570K562TIA1
NBNENSG00000104320.9999.533001320.02060-0.401203.488702.40370K562TRIM56
NBNENSG00000104320.92633.083301911.210200.462203.010001.85810K562U2AF1
NBNENSG00000104320.92513.728101973.669500.348804.126903.14740K562U2AF2
NBNENSG00000104320.91929.131002279.85380-0.241002.954702.21150K562UPF1
NBNENSG00000104320.91608.750001950.79000-0.278102.376901.56350K562WDR3
NBNENSG00000104320.92410.797402028.656700.248903.660502.69660K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NBN is not available on ENCORE database.





17 RBPs can affect the splicing of NBN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENBNENSG00000104320.9chr8-9099418090994230909936029099375190994949909950830.167000.001250.02513includedK562SRSF1
SENBNENSG00000104320.9chr8-9099256690992656909904479099055190992961909931210.088000.000000.00006includedK562SRSF1
SENBNENSG00000104320.9chr8-909936029099375190992961909931219099494990995083-0.070000.002710.04659excludedK562SRSF1
SENBNENSG00000104320.9chr8-9099256690992656909904479099055190992961909931210.077000.000050.06199includedK562RPS3
SENBNENSG00000104320.9chr8-909492539094930390945563909478409095548090955594-0.073000.000540.01261excludedK562SF3B4
SENBNENSG00000104320.9chr8-909941809099423090993602909937519099494990995083-0.171000.001560.04450excludedK562AKAP8L
SENBNENSG00000104320.9chr8-909936029099375190992961909931219099494990995083-0.079000.005200.04801excludedK562AQR
SENBNENSG00000104320.9chr8-909941809099423090993602909937519099494990995083-0.165000.000990.01692excludedK562PUS1
SENBNENSG00000104320.9chr8-909600519096012090945711909478409096547190965919-0.238000.001840.02815excludedK562PUS1
SENBNENSG00000104320.9chr8-909929619099312190990447909905519099360290993751-0.105000.001290.07119excludedHepG2FTO
SENBNENSG00000104320.9chr8-909600519096012090958367909585239096547190965919-0.088000.001060.02370excludedK562U2AF1
SENBNENSG00000104320.9chr8-909904479099055190983400909835189099296190993121-0.067000.002280.04401excludedK562U2AF1
SENBNENSG00000104320.9chr8-909941809099423090993602909937519099494990995083-0.175000.000200.01925excludedK562HNRNPL
SENBNENSG00000104320.9chr8-909936029099375190992961909931219099494990995083-0.077000.001710.09314excludedK562HNRNPUL1
SENBNENSG00000104320.9chr8-909941809099423090993602909937519099494990995083-0.163000.001810.05299excludedK562UTP18
SENBNENSG00000104320.9chr8-909936029099375190992961909931219099494990995083-0.117000.002850.04644excludedK562U2AF2
SENBNENSG00000104320.9chr8-909600519096012090958367909585239096547190965919-0.121000.000050.00167excludedK562U2AF2
SENBNENSG00000104320.9chr8-909904479099055190983400909835189099296190993121-0.059000.005640.07965excludedK562U2AF2
SENBNENSG00000104320.9chr8-909936029099375190992961909931219099494990995083-0.095000.000140.00797excludedK562TARDBP
SENBNENSG00000104320.9chr8-909936029099375190992961909931219099494990995083-0.131000.001440.03590excludedK562RBM15
SENBNENSG00000104320.9chr8-9099256690992656909904479099055190992961909931210.059000.000190.01063includedK562PTBP1
SENBNENSG00000104320.9chr8-9099418090994230909936029099375190994949909950830.228000.001940.03311includedK562HNRNPC
A3SSNBNENSG00000104320.9chr8-9095836790958596909583679095852390960051909601430.059000.000100.00085longerK562AQR
A3SSNBNENSG00000104320.9chr8-909929619099312190992961909930809099360290993751-0.073000.000120.09432shorterK562IGF2BP2
A3SSNBNENSG00000104320.9chr8-909929619099312190992961909930809099360290993751-0.063000.000680.05810shorterK562SRSF1
MXENBNENSG00000104320.9chr8-9099296190993121909936029099375190983400909835189099494990995083-0.199000.000540.020682includedK562RBM15
MXENBNENSG00000104320.9chr8-9099296190993121909936029099375190983400909835189099494990995083-0.231000.000400.009762includedK562U2AF1
MXENBNENSG00000104320.9chr8-9095548090955594909600519096012090945711909478409096547190965919-0.167000.003600.054542includedK562PUS1
MXENBNENSG00000104320.9chr8-90958367909585239096005190960143909554809095559490965471909659190.055000.004820.034821includedK562AQR
MXENBNENSG00000104320.9chr8-9099296190993121909936029099375190983400909835189099494990995083-0.140000.003020.023592includedK562AQR
MXENBNENSG00000104320.9chr8-9099296190993121909936029099375190983400909835189099494990995083-0.225000.000170.003822includedK562U2AF2
MXENBNENSG00000104320.9chr8-9099296190993121909936029099375190983400909835189099494990995083-0.143000.001120.029132includedK562TARDBP
MXENBNENSG00000104320.9chr8-9097095290971082909766379097673590967510909677839098259190982785-0.087000.001900.035172includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NBN is not avaliable on ENCORE database.