MKLN1-AS1

General Information

Gene Name       : MKLN1-AS1
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MKLN1-AS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MKLN1-AS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MKLN1-AS1 RNA is bound by 28 proteins.  







eCLIP assay for MKLN1-AS1 is not avaliable on ENCORE database.





28 proteins are bound to MKLN1-AS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7130790773130790861-intron-Distal3.209305.27455HepG2NKRF
chr7130667217130667271-intron-Distal3.480874.35402HepG2SUGP2
chr7130629365130629437-intron-Distal3.638877.12596K562QKI
chr7130630543130630598-intron-Distal,intron-Proximal3.067874.10087HepG2BCLAF1
chr7130790557130790641-intron-Distal5.3431910.52764K562CSTF2T
chr7130793276130793346-intron-Distal5.545369.61927HepG2U2AF2
chr7130766531130766605-intron-Distal3.137963.00437HepG2HNRNPK
chr7130791359130791402-intron-Distal,intron-Proximal4.537845.18111K562CSTF2T
chr7130668805130668840-intron-Distal,intron-Proximal4.365277.09561HepG2BCLAF1
chr7130784801130784877-intron-Distal4.494566.96007HepG2XPO5
chr7130791447130791513-intron-Distal,intron-Proximal4.601308.48132HepG2RBFOX2
chr7130791006130791096-intron-Distal3.308837.41315K562CSTF2T
chr7130629627130629699-intron-Distal3.936649.27432HepG2QKI
chr7130791099130791178-intron-Distal3.003045.58549HepG2NKRF
chr7130630442130630531-intron-Distal,intron-Proximal3.741284.27261HepG2GRWD1
chr7130737177130737221-intron-Distal,intron-Proximal3.017728.60088HepG2BCLAF1
chr7130763314130763417-intron-Distal3.858964.64467HepG2HNRNPL
chr7130790568130790630-intron-Distal5.1243211.38038HepG2CSTF2T
chr7130705148130705228-intron-Distal4.478093.09122HepG2PTBP1
chr7130789639130789701-intron-Distal3.134648.94958HepG2HNRNPM
chr7130770689130770757-intron-Distal4.433635.28337HepG2HNRNPM
chr7130651415130651534-intron-Distal3.150385.67665K562HNRNPL
chr7130667217130667317-intron-Distal3.965503.33944K562MATR3
chr7130790633130790676-intron-Distal3.283744.23271HepG2HNRNPM
chr7130768819130768966-intron-Distal3.942065.28337HepG2HNRNPM
chr7130629241130629347-intron-Distal4.440584.31512K562KHSRP
chr7130739239130739311-intron-Distal5.432157.38423HepG2PCBP2
chr7130779681130779776-intron-Distal6.8338745.88382HepG2XPO5
chr7130787339130787405-intron-Distal3.456058.61584HepG2HNRNPM
chr7130635495130635562-intron-Distal3.395623.84494HepG2QKI
chr7130641738130641870-intron-Distal4.872233.96879HepG2MATR3
chr7130788501130788574-intron-Distal4.405523.97888HepG2HNRNPL
chr7130772155130772293-intron-Distal3.270423.39857HepG2HNRNPM
chr7130629160130629222-intron-Distal3.738933.01911HepG2U2AF1
chr7130668806130668843-intron-Distal,intron-Proximal3.676894.52024HepG2PPIG
chr7130659210130659256-intron-Distal4.123654.10336HepG2SUGP2
chr7130668840130668868-intron-Distal4.549088.41475HepG2BCLAF1
chr7130764672130764736-intron-Distal3.684903.11000HepG2HNRNPM
chr7130790464130790547-intron-Distal5.355888.23608HepG2HNRNPM
chr7130790574130790649-intron-Distal3.615764.63569HepG2RBFOX2
chr7130634879130634937-intron-Distal3.123504.88763HepG2SUGP2
chr7130757759130757861-intron-Distal4.545445.19234K562LIN28B
chr7130790481130790531-intron-Distal3.394933.28007HepG2NKRF
chr7130788294130788343-intron-Distal3.008643.04298HepG2HNRNPM
chr7130720060130720118-intron-Distal4.652059.41297HepG2PTBP1
chr7130641372130641418-intron-Distal4.212094.10336HepG2SUGP2
chr7130779168130779250-intron-Distal5.068336.19339K562PTBP1
chr7130635656130635718-intron-Distal3.903766.73852HepG2SUGP2
chr7130720002130720077-intron-Distal4.902825.13577HepG2U2AF2
chr7130629664130629722-intron-Distal4.651798.82644HepG2PTBP1
chr7130628805130628922-intron-Distal,intron-Proximal5.389977.22648HepG2CSTF2
chr7130706118130706179-intron-Distal3.082344.83960HepG2RBFOX2
chr7130720038130720060-intron-Distal5.0629814.30440HepG2PTBP1
chr7130791637130791729-intron-Distal4.6542311.24360HepG2CSTF2T
chr7130790554130790633-intron-Distal4.2758811.67714HepG2HNRNPM
chr7130635779130635862-intron-Distal3.595514.84827HepG2HNRNPK
chr7130790567130790606-intron-Distal3.272933.74485K562DROSHA
chr7130630460130630587-intron-Distal,intron-Proximal3.047834.00731K562UCHL5
chr7130651393130651547-intron-Distal5.5100425.83671HepG2HNRNPL
chr7130720707130720811-intron-Distal3.331394.01234HepG2HNRNPL
chr7130661918130661992-intron-Distal4.0133410.67436HepG2XPO5
chr7130733301130733354-intron-Distal5.6899311.26125HepG2HNRNPM
chr7130791130130791169-intron-Distal3.048484.63567K562DROSHA
chr7130661351130661440-intron-Distal3.805636.46902HepG2U2AF2
chr7130720009130720038-intron-Distal4.191797.32475HepG2PTBP1
chr7130787193130787259-intron-Distal3.133265.26084HepG2HNRNPM
chr7130629346130629395-intron-Distal4.355314.52298HepG2QKI
chr7130633698130633778-intron-Distal4.406535.58061HepG2SUGP2
chr7130639971130640027-intron-Distal4.430985.11328HepG2SUGP2
chr7130737041130737119-intron-Distal,intron-Proximal3.881263.02234K562KHSRP
chr7130667195130667281-intron-Distal4.136969.50668HepG2PTBP1
chr7130792505130792549-intron-Distal3.827428.27517K562RBM15
chr7130793559130793679-intron-Distal,intron-Proximal6.2819011.55015HepG2SF3A3
chr7130791078130791096-intron-Distal3.972483.84029K562DROSHA
chr7130790952130791019-intron-Distal4.3148611.41717HepG2CSTF2T
chr7130790804130790843-intron-Distal3.909654.60046HepG2CSTF2T
chr7130635115130635192-intron-Distal4.5450310.37758HepG2SUGP2
chr7130791320130791366-intron-Distal3.420823.41462K562EWSR1
chr7130791105130791189-intron-Distal3.652119.17667K562CSTF2T
chr7130789458130789534-intron-Distal4.5349915.52664HepG2HNRNPM
chr7130632815130632883-intron-Distal3.207253.23296HepG2SUGP2
chr7130633916130633980-intron-Distal3.091593.46325HepG2SUGP2
chr7130790572130790638-intron-Distal3.655018.77204HepG2XRN2
chr7130790416130790500-intron-Distal3.959683.06347K562NONO
chr7130791027130791097-intron-Distal3.168045.68238HepG2CSTF2T
chr7130720011130720095-intron-Distal5.8701811.22261K562PTBP1
chr7130790961130791002-intron-Distal3.216073.42218HepG2XRN2
chr7130640941130640983-intron-Distal3.185053.69184HepG2SUGP2
chr7130752854130752960-intron-Distal3.717765.81300HepG2HNRNPL
chr7130636351130636419-intron-Distal3.313757.69812HepG2SUGP2
chr7130639794130639840-intron-Distal4.022844.03915HepG2SUGP2
chr7130629628130629664-intron-Distal4.244266.10762HepG2PTBP1
chr7130629160130629232-intron-Distal4.3125319.62790HepG2U2AF2
chr7130792616130792673-intron-Distal4.433924.82934K562RBM15
chr7130769951130770015-intron-Distal4.146478.31041HepG2SUGP2
chr7130706179130706253-intron-Distal4.4758910.20880HepG2RBFOX2
chr7130770533130770596-intron-Distal3.558414.28420HepG2HNRNPM
chr7130684227130684280-intron-Distal4.166253.89149HepG2HNRNPK
chr7130782291130782345-intron-Distal4.600604.40618K562PTBP1
chr7130779167130779216-intron-Distal4.681037.55717HepG2PTBP1
chr7130635510130635590-intron-Distal4.5352710.58275HepG2SUGP2
chr7130641552130641600-intron-Distal4.016543.79098HepG2SUGP2
chr7130735648130735745-intron-Distal3.999813.00241HepG2SFPQ
chr7130705911130705958-intron-Distal4.049863.18939HepG2RBFOX2
chr7130770410130770483-intron-Distal3.180036.34497HepG2SUGP2
chr7130748706130748803-intron-Distal3.121703.46866HepG2U2AF2
chr7130667208130667278-intron-Distal5.017055.05386K562PTBP1
chr7130779216130779244-intron-Distal5.196885.75114HepG2PTBP1
chr7130792050130792085-intron-Distal3.054053.17504K562CSTF2T
chr7130789799130789844-intron-Distal5.6943012.96579HepG2HNRNPM
chr7130630534130630599-intron-Distal,intron-Proximal3.705877.83545HepG2PPIG
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MKLN1-AS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MKLN1-AS1 is not available on ENCORE database.

  • 80 RBPs can affect the levels of MKLN1-AS1.  








The Knockdown/knockout RNA-Seq assay for MKLN1-AS1 is not available on ENCORE database.





80 RBPs can affect the gene expression of MKLN1-AS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MKLN1-AS1ENSG00000231721.266.61880133.50780-1.002903.540402.48020HepG2ABCF1
MKLN1-AS1ENSG00000231721.258.17060114.32830-0.974803.992403.28700HepG2ACO1
MKLN1-AS1ENSG00000231721.248.71900163.99270-1.751108.869707.97690HepG2AKAP1
MKLN1-AS1ENSG00000231721.273.84350114.85340-0.637302.108901.42680HepG2AKAP8L
MKLN1-AS1ENSG00000231721.284.2580038.255501.139002.764601.86600HepG2BCLAF1
MKLN1-AS1ENSG00000231721.2131.7576053.092601.311202.892702.19240HepG2CPSF6
MKLN1-AS1ENSG00000231721.260.14760105.73060-0.813803.139602.25600HepG2DDX19B
MKLN1-AS1ENSG00000231721.232.2990076.68660-1.247503.620802.85340HepG2DDX21
MKLN1-AS1ENSG00000231721.291.74720157.10420-0.776002.797502.16860HepG2DDX3X
MKLN1-AS1ENSG00000231721.2127.4242060.293001.079502.948001.94020HepG2DDX59
MKLN1-AS1ENSG00000231721.247.90340109.37750-1.191104.646703.80920HepG2DKC1
MKLN1-AS1ENSG00000231721.242.1922093.26070-1.144303.258202.26380HepG2EEF2
MKLN1-AS1ENSG00000231721.2193.16130129.737100.574102.058301.53830HepG2EIF2S1
MKLN1-AS1ENSG00000231721.234.5508072.43130-1.067902.868901.76930HepG2EIF3G
MKLN1-AS1ENSG00000231721.256.02430111.70630-0.995603.698002.73340HepG2EWSR1
MKLN1-AS1ENSG00000231721.274.09360134.80860-0.863502.767301.99700HepG2FIP1L1
MKLN1-AS1ENSG00000231721.285.3142036.033701.243303.123701.77560HepG2FKBP4
MKLN1-AS1ENSG00000231721.276.65650142.43130-0.893803.324302.34020HepG2G3BP2
MKLN1-AS1ENSG00000231721.221.0034067.40490-1.682204.639603.47460HepG2GEMIN5
MKLN1-AS1ENSG00000231721.243.2611090.90230-1.071203.358502.23000HepG2GNB2L1
MKLN1-AS1ENSG00000231721.236.4889091.27570-1.322804.042603.28380HepG2HNRNPA1
MKLN1-AS1ENSG00000231721.2109.7254050.319601.124604.154703.29480HepG2HNRNPF
MKLN1-AS1ENSG00000231721.2338.59160152.254901.1530013.5533012.16860HepG2HNRNPL
MKLN1-AS1ENSG00000231721.2154.34950100.858200.613802.518301.94000HepG2HNRNPU
MKLN1-AS1ENSG00000231721.296.5363049.548500.962102.741102.02080HepG2IGF2BP1
MKLN1-AS1ENSG00000231721.258.64000127.98250-1.126002.779801.79580HepG2IGF2BP3
MKLN1-AS1ENSG00000231721.2103.15570169.66750-0.717902.563701.76580HepG2LARP4
MKLN1-AS1ENSG00000231721.273.27540145.49910-0.989603.563302.85530HepG2MATR3
MKLN1-AS1ENSG00000231721.290.31640148.88670-0.721202.135001.37100HepG2PABPC1
MKLN1-AS1ENSG00000231721.277.30720132.65770-0.779002.645201.93810HepG2PABPC4
MKLN1-AS1ENSG00000231721.278.68370131.74060-0.743602.846702.23430HepG2PCBP1
MKLN1-AS1ENSG00000231721.2104.04180167.97230-0.691103.143402.52140HepG2PUM1
MKLN1-AS1ENSG00000231721.284.30970167.84510-0.993403.910203.11540HepG2PUM2
MKLN1-AS1ENSG00000231721.2233.58590145.179300.686003.468602.77970HepG2QKI
MKLN1-AS1ENSG00000231721.2144.8732085.374900.762802.002801.39330HepG2RAVER1
MKLN1-AS1ENSG00000231721.2215.18340151.671800.504502.109801.34740HepG2RBM15
MKLN1-AS1ENSG00000231721.2100.09160148.70990-0.571202.115401.64670HepG2RBM22
MKLN1-AS1ENSG00000231721.262.93140149.18620-1.245306.192605.43780HepG2NELFE
MKLN1-AS1ENSG00000231721.2142.9107054.236201.397706.295405.32390HepG2RPLP0
MKLN1-AS1ENSG00000231721.227.1720073.66650-1.438904.178703.43820HepG2RPS19
MKLN1-AS1ENSG00000231721.255.5164099.03920-0.835102.272701.54240HepG2RPS2
MKLN1-AS1ENSG00000231721.268.1953033.023201.046102.012201.33170HepG2RRP9
MKLN1-AS1ENSG00000231721.270.39190160.58650-1.189902.780801.42440HepG2SF1
MKLN1-AS1ENSG00000231721.266.36360126.49350-0.930603.660002.88110HepG2SF3A3
MKLN1-AS1ENSG00000231721.239.60640145.67500-1.8789011.0302010.22260HepG2SRSF1
MKLN1-AS1ENSG00000231721.2158.9459061.172401.377505.844204.34580HepG2SRSF3
MKLN1-AS1ENSG00000231721.278.31270156.23500-0.996404.891204.09690HepG2SRSF5
MKLN1-AS1ENSG00000231721.2153.8715049.444201.6378010.156608.96970HepG2SRSF7
MKLN1-AS1ENSG00000231721.251.15700145.80920-1.511109.158308.33070HepG2SSB
MKLN1-AS1ENSG00000231721.270.15150177.67470-1.340708.729607.72890HepG2SUCLG1
MKLN1-AS1ENSG00000231721.251.6190091.02080-0.818302.433101.54710HepG2SUPT6H
MKLN1-AS1ENSG00000231721.292.61580154.59310-0.739102.735001.86680HepG2TUFM
MKLN1-AS1ENSG00000231721.2160.2547025.455202.6542019.6349017.65510HepG2UCHL5
MKLN1-AS1ENSG00000231721.2536.51510396.880800.434802.313101.71440K562AKAP8L
MKLN1-AS1ENSG00000231721.2602.63230416.456400.533003.293002.28950K562ATP5C1
MKLN1-AS1ENSG00000231721.2235.58800128.503300.874405.686503.51540K562CEBPZ
MKLN1-AS1ENSG00000231721.2219.61020131.271700.742303.748902.83650K562CPSF6
MKLN1-AS1ENSG00000231721.2241.75940147.690400.710904.210002.69640K562DDX21
MKLN1-AS1ENSG00000231721.270.77910225.07690-1.669008.673407.60000K562DDX47
MKLN1-AS1ENSG00000231721.210.6121081.87900-2.947808.722606.90100K562EIF3A
MKLN1-AS1ENSG00000231721.252.9820096.69180-0.867902.483701.50920K562EIF3D
MKLN1-AS1ENSG00000231721.230.84700111.49370-1.853809.144007.70160K562EIF3G
MKLN1-AS1ENSG00000231721.2259.38790174.777600.569502.908102.06730K562EIF4A3
MKLN1-AS1ENSG00000231721.2174.05840113.234400.620202.301101.47170K562FTO
MKLN1-AS1ENSG00000231721.244.84590181.76260-2.0190015.8295014.49270K562FXR1
MKLN1-AS1ENSG00000231721.2618.06420381.464900.696102.830401.59450K562HNRNPA2B1
MKLN1-AS1ENSG00000231721.2291.29110166.235400.809105.936104.61840K562HNRNPU
MKLN1-AS1ENSG00000231721.2615.87010421.128900.548303.534702.58980K562KIF1C
MKLN1-AS1ENSG00000231721.2195.32190107.032400.867703.412902.36370K562KRR1
MKLN1-AS1ENSG00000231721.2584.43720403.173300.535503.494902.24090K562MAK16
MKLN1-AS1ENSG00000231721.2542.24420330.688400.713404.751103.49660K562NAA15
MKLN1-AS1ENSG00000231721.2320.05800166.458100.943108.801607.57200K562NSUN2
MKLN1-AS1ENSG00000231721.2121.70290181.27390-0.574802.502201.86630K562PTBP1
MKLN1-AS1ENSG00000231721.2623.29170393.472700.663504.615103.93690K562PUS1
MKLN1-AS1ENSG00000231721.2299.16410170.209200.813503.536201.89410K562RAVER1
MKLN1-AS1ENSG00000231721.2110.49830182.92190-0.727203.301702.09520K562NELFE
MKLN1-AS1ENSG00000231721.225.3999089.51470-1.817306.517905.25340K562RPS19
MKLN1-AS1ENSG00000231721.2166.53730337.00410-1.016906.492404.87970K562RPS3
MKLN1-AS1ENSG00000231721.254.06200138.97680-1.362205.300703.79820K562SAFB
MKLN1-AS1ENSG00000231721.2198.59200119.217300.736102.939801.93580K562SF3B1
MKLN1-AS1ENSG00000231721.2153.0239088.662300.787303.127101.77900K562SLBP
MKLN1-AS1ENSG00000231721.2208.0319088.574501.231704.314701.79000K562SMNDC1
MKLN1-AS1ENSG00000231721.2701.44720350.481401.000902.979801.68850K562SNRNP200
MKLN1-AS1ENSG00000231721.267.19110177.70780-1.403208.626507.38190K562SRSF1
MKLN1-AS1ENSG00000231721.2259.74320131.784300.978807.798505.84270K562SRSF7
MKLN1-AS1ENSG00000231721.2155.0679085.087000.865803.318102.19720K562SUPV3L1
MKLN1-AS1ENSG00000231721.243.33100156.47400-1.8525011.427709.77070K562SYNCRIP
MKLN1-AS1ENSG00000231721.2250.97120176.499700.507802.636501.93560K562UPF1
MKLN1-AS1ENSG00000231721.2332.64860151.024101.139103.382302.41810K562WDR3
MKLN1-AS1ENSG00000231721.2409.91750259.911500.657202.039101.31100K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MKLN1-AS1 is not available on ENCORE database.





4 RBPs can affect the splicing of MKLN1-AS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMKLN1-AS1ENSG00000231721.2chr7-1306521471306522761306303681306305941306688111306688680.239000.000240.03679includedHepG2HNRNPM
SEMKLN1-AS1ENSG00000231721.2chr7-130652147130652276130630368130630594130668811130668868-0.207000.000000.00002excludedK562PUS1
SEMKLN1-AS1ENSG00000231721.2chr7-130652147130652276130630368130630594130668811130668868-0.153000.005020.09136excludedK562RBM15
SEMKLN1-AS1ENSG00000231721.2chr7-130652147130652276130630368130630594130668811130668868-0.163000.001650.04095excludedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MKLN1-AS1 is not avaliable on ENCORE database.