LCORL

General Information

Gene Name       : LCORL
Gene ID             : ENSG00000178177.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LCORL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LCORLENSG00000178177.154.893.554.22ENCSR000AEF
HepG2LCORLENSG00000178177.152.996.284.63ENCSR985KAT
K562LCORLENSG00000178177.156.667.467.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LCORL is not avaliable on ENCORE database.



Proteins bound to RNA
  • LCORL RNA is bound by 22 proteins.  







eCLIP assay for LCORL is not avaliable on ENCORE database.





22 proteins are bound to LCORL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr41788521217885315-3'-UTR,intron-Distal4.8120514.72456K562TARDBP
chr41784703217847155-3'-UTR,intron-Distal,intron-Proximal4.575786.27552K562KHSRP
chr41788232817882435-3'-UTR,intron-Distal4.078263.75546HepG2KHSRP
chr41784695217847032-3'-UTR,intron-Distal,intron-Proximal4.166844.58794K562KHSRP
chr41791092717910989-3'-UTR,CDS,intron-Distal,intron-Proximal4.116375.60471HepG2U2AF2
chr41796461617964673-5'-UTR,CDS,intron-Distal,intron-Proximal4.223454.08604HepG2PPIG
chr41797444217974479-5'-UTR,CDS,intron-Distal,intron-Proximal4.111843.45943HepG2BCLAF1
chr41802326518023383-5'-UTR,CDS,intron-Distal,intron-Proximal3.621874.85956HepG2NCBP2
chr41796353617963653-5'-UTR,CDS,intron-Distal4.760347.71151HepG2GRWD1
chr41795692917957005-intron-Distal3.264826.81350K562MATR3
chr41795745417957512-intron-Distal3.885026.98738HepG2SUGP2
chr41786075317860912-intron-Distal3.581836.00711K562HNRNPL
chr41800737318007418-intron-Distal4.496793.85055HepG2XPO5
chr41794965317949754-intron-Distal3.811243.37631K562HNRNPL
chr41795979417959907-intron-Distal4.869744.20763HepG2U2AF2
chr41801204418012088-intron-Distal3.770053.51804HepG2HNRNPL
chr41795857717958698-intron-Distal4.925555.41368HepG2PTBP1
chr41787554617875625-intron-Distal4.048964.51328K562SAFB2
chr41795633717956473-intron-Distal4.3871214.02890HepG2SUGP2
chr41802257618022664-intron-Distal3.759864.93080K562AKAP8L
chr41796866017968747-intron-Distal3.745613.02234K562KHSRP
chr41799937017999440-intron-Distal8.0883953.26055K562QKI
chr41795674417956814-intron-Distal4.783296.75776K562MATR3
chr41800419118004258-intron-Distal3.301433.46531K562KHSRP
chr41795711017957144-intron-Distal3.992413.86809HepG2SUGP2
chr41802292618022971-intron-Distal3.876133.53896K562NONO
chr41802256618022641-intron-Distal4.223703.07008K562NONO
chr41799932517999353-intron-Distal3.405883.84727K562QKI
chr41790404917904094-intron-Distal3.398614.76345K562KHSRP
chr41795045817950533-intron-Distal3.640083.62418K562PTBP1
chr41795952617959581-intron-Distal3.048215.62143K562KHSRP
chr41801204318012078-intron-Distal3.322906.65670K562HNRNPL
chr41795640217956474-intron-Distal3.451846.70640K562MATR3
chr41802292018022983-intron-Distal3.521104.71867K562TIA1
chr41795886217958948-intron-Distal4.815326.36848HepG2SUGP2
chr41795605717956105-intron-Distal4.528264.75674K562MATR3
chr41795736717957436-intron-Distal4.631136.48506K562MATR3
chr41798372717983812-intron-Distal4.124224.45537HepG2HNRNPL
chr41787697217877083-intron-Distal4.751426.91685K562SAFB2
chr41795626317956305-intron-Distal3.482534.84410HepG2SUGP2
chr41800330418003403-intron-Distal5.5547411.80112K562KHSRP
chr41787632517876387-intron-Distal3.852383.10466K562SAFB2
chr41795902817959154-intron-Distal4.078037.55788K562MATR3
chr41802306618023121-intron-Distal4.386895.42636K562NONO
chr41799532817995393-intron-Distal4.201424.67922K562PTBP1
chr41795641317956443-intron-Distal4.328503.62238HepG2MATR3
chr41791059517910645-intron-Distal,intron-Proximal4.290805.41654K562KHSRP
chr41799932817999432-intron-Distal6.0045711.86079HepG2QKI
chr41801198418012034-intron-Distal4.6742912.76474K562AGGF1
chr41799533017995418-intron-Distal4.372343.09122HepG2PTBP1
chr41800340318003503-intron-Distal4.054997.46973K562KHSRP
chr41798876617988876-intron-Distal3.904893.50894K562SAFB2
chr41787825717878327-intron-Distal3.866233.43228K562SAFB2
chr41795685617956912-intron-Distal4.939267.55950K562MATR3
chr41802258818022654-intron-Distal3.144513.41957K562DROSHA
chr41801528518015315-intron-Distal4.406783.30425K562LIN28B
chr41795857417958700-intron-Distal4.505577.08067K562PTBP1
chr41795692417957021-intron-Distal5.154126.43853HepG2MATR3
chr41790412617904171-intron-Distal3.680014.93120K562KHSRP
chr41795875817958813-intron-Distal3.909513.45817K562MATR3
chr41801201018012044-intron-Distal4.873844.77636HepG2HNRNPL
chr41794450117944571-intron-Distal4.619353.70058HepG2XPO5
chr41794074317940818-intron-Distal3.742755.98773K562KHSRP
chr41793439017934509-intron-Distal4.086714.79278K562SAFB
chr41795665217956737-intron-Distal3.8592510.49455HepG2SUGP2
chr41793063617930690-intron-Distal5.038788.27925K562KHSRP
chr41790417117904241-intron-Distal4.278048.75974K562KHSRP
chr41793069117930737-intron-Distal4.080363.42844K562KHSRP
chr41795023817950342-intron-Distal3.624594.03284K562MATR3
chr41786861217868663-intron-Distal3.968444.21358HepG2U2AF2
chr41795947217959526-intron-Distal3.486544.08064K562KHSRP
chr41795751217957583-intron-Distal3.372256.28047HepG2SUGP2
chr41801194318012043-intron-Distal4.8758822.77814K562HNRNPL
chr41793424617934315-intron-Distal3.702483.33309K562SAFB
chr41791111817911249-intron-Distal3.452744.10408K562KHSRP
chr41793051417930601-intron-Distal4.392458.75493K562KHSRP
chr41795651117956561-intron-Distal4.742216.10726HepG2SUGP2
chr41801197318012010-intron-Distal4.397025.30852HepG2HNRNPL
chr41795721117957285-intron-Distal4.913937.82233K562MATR3
chr41787712517877187-intron-Distal3.961473.84033K562SAFB2
chr41787562517875706-intron-Distal4.647316.48449K562SAFB2
chr41794064017940743-intron-Distal3.045275.65129K562KHSRP
chr41791277517912852-intron-Distal4.258874.35360K562QKI
chr41785591817856002-intron-Distal4.745034.85866HepG2QKI
chr41795685517956919-intron-Distal3.799464.81844HepG2SUGP2
chr41791460317914647-intron-Distal3.122293.23296HepG2SUGP2
chr41787631017876362-intron-Distal3.221013.07152HepG2HLTF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LCORL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LCORL is not available on ENCORE database.

  • 80 RBPs can affect the levels of LCORL.  








The Knockdown/knockout RNA-Seq assay for LCORL is not available on ENCORE database.





80 RBPs can affect the gene expression of LCORL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LCORLENSG00000178177.10382.12190536.11090-0.488502.433501.93150HepG2AKAP1
LCORLENSG00000178177.10263.09910358.23040-0.445302.814202.04160HepG2AKAP8L
LCORLENSG00000178177.10143.72930283.63060-0.980704.756603.52930HepG2BCCIP
LCORLENSG00000178177.10304.45200401.27780-0.398402.216201.52130HepG2CALR
LCORLENSG00000178177.10346.29460514.69570-0.571702.618101.87460HepG2CNOT7
LCORLENSG00000178177.10226.58700320.52750-0.500402.965701.91240HepG2YBX3
LCORLENSG00000178177.10268.84400458.43970-0.770007.808506.83140HepG2CELF1
LCORLENSG00000178177.10146.65370285.82440-0.962706.848505.82990HepG2DDX21
LCORLENSG00000178177.10136.34760278.84730-1.032205.176204.15910HepG2DDX55
LCORLENSG00000178177.10186.71420311.94120-0.740406.377905.44680HepG2DNAJC2
LCORLENSG00000178177.10238.13320354.20560-0.572802.870901.93360HepG2EEF2
LCORLENSG00000178177.10252.45270424.12420-0.748504.918004.13940HepG2EIF2S1
LCORLENSG00000178177.10266.34540468.74850-0.815503.605702.87840HepG2EIF4A3
LCORLENSG00000178177.10340.33320494.47030-0.538902.545101.80330HepG2FIP1L1
LCORLENSG00000178177.10335.30270245.571200.449202.322201.59820HepG2FUBP3
LCORLENSG00000178177.10226.75530400.47400-0.820604.922903.45930HepG2FUS
LCORLENSG00000178177.10356.49560472.82230-0.407401.995901.40410HepG2FXR1
LCORLENSG00000178177.10301.47040438.67790-0.541102.989302.29910HepG2G3BP1
LCORLENSG00000178177.10310.13410476.44150-0.619403.207802.00280HepG2GRSF1
LCORLENSG00000178177.10317.24510248.035500.355001.950601.34160HepG2HNRNPF
LCORLENSG00000178177.10365.30400449.04650-0.297801.915401.34160HepG2HNRNPL
LCORLENSG00000178177.10168.75630351.11980-1.0570011.7184010.54330HepG2HNRNPU
LCORLENSG00000178177.10332.56070445.93000-0.423202.079101.48490HepG2IGF2BP2
LCORLENSG00000178177.10361.07340609.00650-0.754202.434001.65840HepG2LARP4
LCORLENSG00000178177.10252.48960400.36030-0.665103.784602.84200HepG2MSI2
LCORLENSG00000178177.10361.79050486.87530-0.428402.102501.54710HepG2NCBP2
LCORLENSG00000178177.10285.42600488.80920-0.776207.982106.70780HepG2NOL12
LCORLENSG00000178177.10419.20810284.943000.556903.154802.35680HepG2NSUN2
LCORLENSG00000178177.10245.22160347.56620-0.503203.337102.41510HepG2PARN
LCORLENSG00000178177.10395.26100300.154100.397002.429301.69900HepG2PRPF4
LCORLENSG00000178177.10356.98280466.60660-0.386402.175801.63800HepG2PUF60
LCORLENSG00000178177.10317.70760495.31800-0.640707.189906.32650HepG2PUM1
LCORLENSG00000178177.10254.24290363.17500-0.514503.741603.04770HepG2PUS1
LCORLENSG00000178177.10586.46630464.440000.336502.077201.32110HepG2RBM15
LCORLENSG00000178177.10388.48780507.62270-0.385902.663802.15290HepG2RBM22
LCORLENSG00000178177.10136.86570279.78640-1.031607.648206.68670HepG2RPS19
LCORLENSG00000178177.10316.10140516.74530-0.709104.402503.39240HepG2RPS3A
LCORLENSG00000178177.10143.37250280.79100-0.969706.261304.86140HepG2SERBP1
LCORLENSG00000178177.10427.62480318.112400.426702.294901.64960HepG2SF3B1
LCORLENSG00000178177.10186.51260364.67050-0.9673010.728409.59450HepG2SMN1
LCORLENSG00000178177.10256.55360372.73250-0.538902.585101.66140HepG2SMNDC1
LCORLENSG00000178177.10821.35890573.332600.518506.043305.38190HepG2SRFBP1
LCORLENSG00000178177.10255.92130460.69950-0.848109.408608.34700HepG2SRSF5
LCORLENSG00000178177.10308.01750386.15230-0.326201.966101.48600HepG2SRSF9
LCORLENSG00000178177.10191.11830330.42750-0.789903.889502.44430HepG2STAU1
LCORLENSG00000178177.10381.57800523.94780-0.457403.939103.22050HepG2SUCLG1
LCORLENSG00000178177.10567.44390392.022900.533404.532203.46970HepG2TIA1
LCORLENSG00000178177.10260.41810341.23170-0.389902.026601.58470HepG2TIAL1
LCORLENSG00000178177.10207.55260344.22500-0.729906.314405.52480HepG2TRIM56
LCORLENSG00000178177.10550.16890423.083100.378802.116901.55920HepG2U2AF1
LCORLENSG00000178177.10285.71630482.49990-0.755904.900203.76340HepG2UBE2L3
LCORLENSG00000178177.1076.37460164.02090-1.102705.125304.08330HepG2UCHL5
LCORLENSG00000178177.10343.71680461.83860-0.426203.473402.88030HepG2ZNF622
LCORLENSG00000178177.101178.57250846.091100.478106.961006.11970K562AGGF1
LCORLENSG00000178177.101149.87430929.762100.306402.313901.42760K562AKAP8
LCORLENSG00000178177.10701.183301050.30200-0.582905.969404.04090K562APOBEC3C
LCORLENSG00000178177.101249.73500923.773400.435905.530304.18650K562ATP5C1
LCORLENSG00000178177.10640.90890967.15740-0.593602.336001.37520K562CNOT7
LCORLENSG00000178177.10325.19730675.62410-1.0549014.7705012.92940K562CPSF6
LCORLENSG00000178177.101209.23340947.323500.352103.969402.89530K562DKC1
LCORLENSG00000178177.10591.50920821.62430-0.474105.432903.71090K562EIF2S1
LCORLENSG00000178177.10344.46600487.09950-0.499903.752402.83610K562EIF3G
LCORLENSG00000178177.10491.32270781.46110-0.669506.895305.60870K562EIF4A3
LCORLENSG00000178177.10921.792301190.32900-0.368803.975502.85340K562EIF4G2
LCORLENSG00000178177.10391.20900566.16300-0.533303.902702.88470K562FIP1L1
LCORLENSG00000178177.10359.59580812.68940-1.1763023.2935021.65610K562FXR1
LCORLENSG00000178177.101227.00580776.378500.660205.247904.20270K562G3BP2
LCORLENSG00000178177.10463.53360645.02660-0.476703.515002.62420K562GPKOW
LCORLENSG00000178177.10294.79440574.98180-0.9638010.589609.48390K562HNRNPC
LCORLENSG00000178177.10591.65590904.83180-0.612906.736705.01540K562HNRNPL
LCORLENSG00000178177.10296.26340465.68030-0.652504.121002.96860K562HNRNPM
LCORLENSG00000178177.10464.11950704.63200-0.602406.794605.39240K562HNRNPU
LCORLENSG00000178177.10607.58720767.59250-0.337202.101701.40500K562HSPD1
LCORLENSG00000178177.101268.89730934.298800.441504.561403.45940K562KIF1C
LCORLENSG00000178177.10635.79690936.05350-0.558003.010402.13260K562MAGOH
LCORLENSG00000178177.101110.28540894.378900.311902.350701.38720K562MAK16
LCORLENSG00000178177.10485.93320934.24450-0.943006.347404.86830K562MATR3
LCORLENSG00000178177.101362.957001046.654900.380903.663002.59260K562MBNL1
LCORLENSG00000178177.10558.49960704.75500-0.335602.848202.02800K562MTPAP
LCORLENSG00000178177.101002.19990733.632000.449902.651701.79110K562NAA15
LCORLENSG00000178177.10999.802101302.07600-0.381103.418701.74310K562NOL12
LCORLENSG00000178177.10652.87820783.01100-0.262202.235001.55750K562NSUN2
LCORLENSG00000178177.10242.95870371.04070-0.610903.399102.56570K562PRPF8
LCORLENSG00000178177.10432.98490909.39040-1.070606.946305.93030K562PTBP1
LCORLENSG00000178177.10915.542801298.71920-0.504405.577804.42120K562PUF60
LCORLENSG00000178177.101197.05580850.714900.492606.362605.48930K562RBM15
LCORLENSG00000178177.10504.35210872.32000-0.790404.914203.75450K562RBM22
LCORLENSG00000178177.10467.07150817.94830-0.808407.558305.79180K562RPS3
LCORLENSG00000178177.10255.13470361.72570-0.503602.734801.66090K562SAFB
LCORLENSG00000178177.10491.33040891.43940-0.859405.805204.78900K562SRSF1
LCORLENSG00000178177.10308.30280407.14210-0.401202.080101.36770K562SYNCRIP
LCORLENSG00000178177.10540.44810902.33790-0.739504.385503.48770K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LCORL is not available on ENCORE database.





14 RBPs can affect the splicing of LCORL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELCORLENSG00000178177.10chr4-178876901788778417842821178475241791071617910968-0.442000.000020.00145excludedK562PRPF8
SELCORLENSG00000178177.10chr4-178876901788778417842821178475241796352517963655-0.191000.001860.05064excludedK562AKAP8L
SELCORLENSG00000178177.10chr4-1796188717961934179107161791096817963525179636550.067000.000060.02708includedK562PUM1
SELCORLENSG00000178177.10chr4-1796459217964672179635251796365517974442179745080.063000.000680.08086includedK562LARP4
SELCORLENSG00000178177.10chr4-178876901788778417842821178475241791071617910968-0.388000.000010.00131excludedK562EFTUD2
SELCORLENSG00000178177.10chr4-179645921796467217963516179636551797444217974508-0.137000.000240.02196excludedK562HNRNPL
SELCORLENSG00000178177.10chr4-178876901788778417842821178475241791071617910968-0.352000.000120.00541excludedHepG2SF3A3
SELCORLENSG00000178177.10chr4-179107161791096817847119178475241796352517963655-0.141000.000470.01058excludedK562U2AF2
SELCORLENSG00000178177.10chr4-1796459217964672179635251796365517974442179745080.182000.001900.06595includedK562SF3B1
SELCORLENSG00000178177.10chr4-178876901788778417842821178475241791071617910968-0.236000.002200.08152excludedK562HNRNPK
SELCORLENSG00000178177.10chr4-1788769017887784178428211784752417910716179109680.486000.000180.01651includedHepG2SRSF9
A3SSLCORLENSG00000178177.10chr4-1788769017887808178876901788778417910716179109680.056000.015790.07808longerK562AQR
MXELCORLENSG00000178177.10chr4-1788769017887784179107161791096817882251178863751796352517963655-0.283000.001450.078462includedHepG2G3BP1
MXELCORLENSG00000178177.10chr4-17887690178877841791071617910968178822511788637517963525179636550.227000.003920.054711includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LCORL is not avaliable on ENCORE database.