JTB

General Information

Gene Name       : JTB
Gene ID             : ENSG00000143543.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: JTB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878JTBENSG00000143543.1436.4958.4947.49ENCSR000AEF
HepG2JTBENSG00000143543.1449.5544.9847.27ENCSR985KAT
K562JTBENSG00000143543.1497.0872.5484.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for JTB is not avaliable on ENCORE database.



Proteins bound to RNA
  • JTB RNA is bound by 19 proteins.  







eCLIP assay for JTB is not avaliable on ENCORE database.





19 proteins are bound to JTB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1153947025153947065-3'-UTR,intron-Distal,intron-Proximal4.952179.84602K562PABPC4
chr1153947096153947141-3'-UTR,intron-Distal,intron-Proximal3.170033.81856K562IGF2BP1
chr1153947148153947235-3'-UTR,CDS,intron-Distal,intron-Proximal3.333545.23541HepG2YBX3
chr1153947034153947103-3'-UTR,intron-Distal,intron-Proximal3.228584.06768K562NOLC1
chr1153947029153947100-3'-UTR,intron-Distal,intron-Proximal4.320679.91456HepG2SUB1
chr1153949735153949845-5'-UTR,intron-Distal5.0452345.37810HepG2DDX3X
chr1153949487153949552-5'-UTR,CDS,intron-Distal,intron-Proximal4.127657.97087HepG2XPO5
chr1153949980153950039-5'-UTR,intron-Distal3.380933.82830HepG2LARP4
chr1153950062153950130-5'-UTR,intron-Distal,intron-Proximal3.9663112.63060K562DDX3X
chr1153950014153950121-5'-UTR,intron-Distal,intron-Proximal5.4119057.90253HepG2DDX3X
chr1153949572153949649-5'-UTR,CDS,intron-Distal,intron-Proximal3.266446.15266HepG2PRPF8
chr1153949457153949519-5'-UTR,CDS,intron-Distal,intron-Proximal4.4909811.08359K562AQR
chr1153949354153949396-5'-UTR,intron-Distal,intron-Proximal3.983074.04622HepG2GRWD1
chr1153949615153949647-5'-UTR,CDS,intron-Distal,intron-Proximal3.801575.56912HepG2AQR
chr1153949356153949410-5'-UTR,intron-Distal,intron-Proximal3.181198.18935K562BUD13
chr1153949312153949392-5'-UTR,intron-Distal,intron-Proximal4.065453.95991K562U2AF2
chr1153949445153949513-5'-UTR,CDS,intron-Distal,intron-Proximal3.238934.65237HepG2U2AF2
chr1153949442153949457-5'-UTR,CDS,intron-Distal,intron-Proximal6.1233123.38793K562AQR
chr1153949366153949443-5'-UTR,intron-Distal,intron-Proximal3.604414.86939K562EFTUD2
chr1153949409153949444-5'-UTR,intron-Distal,intron-Proximal3.825887.85990HepG2PRPF8
chr1153949427153949520-5'-UTR,CDS,intron-Distal,intron-Proximal4.5465210.38579HepG2AQR
chr1153949933153950014-5'-UTR,intron-Distal,intron-Proximal4.5577750.66053HepG2DDX3X
chr1153949841153949914-5'-UTR,intron-Distal,intron-Proximal5.5871512.85380K562RBM15
chr1153949442153949566-5'-UTR,CDS,intron-Distal,intron-Proximal4.5219521.19110HepG2EFTUD2
chr1153950020153950062-5'-UTR,intron-Distal3.9948713.18532K562DDX3X
chr1153949410153949446-5'-UTR,intron-Distal,intron-Proximal3.508715.59104K562BUD13
chr1153949407153949414-5'-UTR,intron-Distal,intron-Proximal6.0062521.77166K562AQR
chr1153949414153949442-5'-UTR,intron-Distal,intron-Proximal6.1530725.00748K562AQR
chr1153949367153949396-5'-UTR,intron-Distal,intron-Proximal4.3402710.81562K562AQR
chr1153950071153950115-5'-UTR,intron-Distal,intron-Proximal5.502944.56463K562GEMIN5
chr1153949244153949294-5'-UTR,CDS,intron-Distal,intron-Proximal3.901375.75388HepG2BUD13
chr1153949182153949294-5'-UTR,CDS,intron-Distal,intron-Proximal4.2584512.81671K562SF3B4
chr1153949677153949731-5'-UTR,CDS,intron-Distal5.1013526.79204HepG2DDX3X
chr1153949934153950020-5'-UTR,intron-Distal,intron-Proximal4.8202722.08593K562DDX3X
chr1153949197153949297-5'-UTR,CDS,intron-Distal,intron-Proximal5.372468.90499HepG2AQR
chr1153949444153949502-5'-UTR,CDS,intron-Distal,intron-Proximal3.9429110.32093HepG2PRPF8
chr1153949396153949407-5'-UTR,intron-Distal,intron-Proximal4.292568.79285K562AQR
chr1153949468153949539-5'-UTR,CDS,intron-Distal,intron-Proximal3.456127.52067K562EFTUD2
chr1153949200153949291-5'-UTR,CDS,intron-Distal,intron-Proximal3.043908.72081K562BUD13
chr1153950074153950121-5'-UTR,intron-Distal,intron-Proximal4.635105.38274HepG2NCBP2
chr1153947180153947193-CDS,intron-Distal4.3116232.18117K562YBX3
chr1153947174153947272-CDS,intron-Distal3.198327.95442HepG2GRWD1
chr1153949191153949276-CDS,intron-Distal,intron-Proximal4.3507226.91592K562AQR
chr1153947193153947227-CDS,intron-Distal4.0977452.09073K562YBX3
chr1153947161153947168-CDS,intron-Distal3.437315.38711K562YBX3
chr1153947173153947180-CDS,intron-Distal3.6843117.63090K562YBX3
chr1153948354153948436-CDS,intron-Distal,intron-Proximal3.031524.21220K562SMNDC1
chr1153947218153947247-CDS,intron-Distal4.136113.98353K562RBM15
chr1153948350153948432-CDS,intron-Distal,intron-Proximal3.7738916.37801K562SF3B4
chr1153948265153948277-intron-Distal,intron-Proximal4.973856.22530K562AQR
chr1153949566153949639-intron-Distal,intron-Proximal6.1503324.13081HepG2EFTUD2
chr1153949572153949615-intron-Distal,intron-Proximal4.604434.28193HepG2AQR
chr1153949552153949621-intron-Distal,intron-Proximal4.9526121.24993HepG2XPO5
chr1153949551153949628-intron-Distal,intron-Proximal4.950807.63242K562EFTUD2
chr1153949586153949642-intron-Distal,intron-Proximal3.134819.16958K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for JTB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for JTB is not available on ENCORE database.

  • 76 RBPs can affect the levels of JTB.  








The Knockdown/knockout RNA-Seq assay for JTB is not available on ENCORE database.





76 RBPs can affect the gene expression of JTB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
JTBENSG00000143543.101166.46600912.824400.353602.247001.53550HepG2ASCC1
JTBENSG00000143543.10924.880101115.66010-0.270602.540401.87800HepG2AUH
JTBENSG00000143543.10368.07240583.94790-0.665902.276101.43040HepG2BCCIP
JTBENSG00000143543.10371.93150256.028000.538603.003202.38260HepG2BOP1
JTBENSG00000143543.10261.51000355.27810-0.442102.480201.74690HepG2CALR
JTBENSG00000143543.10375.87800574.21110-0.611302.032301.35900HepG2DDX55
JTBENSG00000143543.10157.54360266.90810-0.760602.883001.88510HepG2DDX59
JTBENSG00000143543.10395.42840964.33110-1.2861017.3162015.72610HepG2EIF4A3
JTBENSG00000143543.101078.81980846.573600.349602.425801.66050HepG2EIF4G2
JTBENSG00000143543.10394.70880572.55350-0.536604.044703.10180HepG2FUBP3
JTBENSG00000143543.10669.53860823.25220-0.298202.440901.55540HepG2HNRNPA2B1
JTBENSG00000143543.10159.99250254.24860-0.668203.145302.47930HepG2HNRNPLL
JTBENSG00000143543.10347.30330493.62830-0.507202.241501.69020HepG2HNRNPU
JTBENSG00000143543.10186.08290421.90080-1.181007.597405.60690HepG2HSPD1
JTBENSG00000143543.10540.11060861.20740-0.673102.215201.34450HepG2IGF2BP3
JTBENSG00000143543.10732.17570521.947800.488202.795601.96100HepG2LARP4
JTBENSG00000143543.10325.50360501.06740-0.622302.529501.37340HepG2LIN28B
JTBENSG00000143543.10565.53280978.95540-0.791607.402906.40920HepG2MATR3
JTBENSG00000143543.10666.89120888.25740-0.413503.786802.89340HepG2NOL12
JTBENSG00000143543.10655.18170940.02040-0.520807.171306.37120HepG2PTBP1
JTBENSG00000143543.10629.868601018.12440-0.692809.941908.86090HepG2QKI
JTBENSG00000143543.10314.26790530.67230-0.755807.718106.38860HepG2RBM15
JTBENSG00000143543.10833.330101070.63300-0.361503.573803.00560HepG2RBM22
JTBENSG00000143543.10740.58180923.99100-0.319202.352401.72500HepG2RBM25
JTBENSG00000143543.10693.069201046.17550-0.594108.846307.97940HepG2NELFE
JTBENSG00000143543.10716.93290974.32840-0.442605.306904.48770HepG2RECQL
JTBENSG00000143543.10778.02000978.73230-0.331103.254002.61930HepG2SF3B4
JTBENSG00000143543.10931.219101209.23180-0.376904.772804.16620HepG2SRFBP1
JTBENSG00000143543.10573.624801021.56430-0.8326015.9707015.03370HepG2SRSF1
JTBENSG00000143543.10620.66790831.07950-0.421204.884204.18920HepG2SRSF9
JTBENSG00000143543.10677.08620843.72880-0.317402.418001.63470HepG2TIA1
JTBENSG00000143543.10641.65660876.83170-0.450502.580201.77170HepG2UBE2L3
JTBENSG00000143543.10512.24420337.535500.601702.697701.94840HepG2UCHL5
JTBENSG00000143543.10549.21940457.827400.262501.822501.35320HepG2ZNF622
JTBENSG00000143543.102082.372901542.534700.432807.561006.68830K562AGGF1
JTBENSG00000143543.102274.622201694.950100.424304.266102.99020K562AKAP8
JTBENSG00000143543.102401.088401605.061900.581006.384805.36150K562AKAP8L
JTBENSG00000143543.102106.141603059.18490-0.538505.051504.30150K562AQR
JTBENSG00000143543.102301.991801684.067400.450807.002105.45620K562ATP5C1
JTBENSG00000143543.10909.928101438.63920-0.6609012.500509.69340K562BCCIP
JTBENSG00000143543.10477.97610719.71390-0.590505.091103.56190K562CCAR1
JTBENSG00000143543.102847.106703509.35660-0.301704.035002.84850K562CELF1
JTBENSG00000143543.101730.000801452.978800.251702.798602.14230K562DDX47
JTBENSG00000143543.10519.96820805.67540-0.631805.759303.71270K562DHX30
JTBENSG00000143543.102116.175101727.257700.292903.435902.44540K562DKC1
JTBENSG00000143543.10511.35820773.95360-0.597905.405703.52160K562DNAJC21
JTBENSG00000143543.10490.86210732.09100-0.576702.877201.84950K562EIF3A
JTBENSG00000143543.101245.43920971.380100.358403.761402.84350K562EIF3G
JTBENSG00000143543.101037.145601488.69610-0.521405.765204.58610K562EIF4A3
JTBENSG00000143543.10829.683001079.35520-0.379503.370101.95400K562EXOSC5
JTBENSG00000143543.101425.428301078.736800.402002.701001.86280K562FIP1L1
JTBENSG00000143543.10506.85750712.04400-0.490403.462502.50240K562FMR1
JTBENSG00000143543.10440.67590603.51310-0.453702.669101.77140K562FTO
JTBENSG00000143543.10865.049001135.44090-0.392402.697501.30280K562GEMIN5
JTBENSG00000143543.103206.987302512.862200.351803.156202.35150K562GRSF1
JTBENSG00000143543.101634.172601993.21870-0.286502.558201.52440K562HNRNPA1
JTBENSG00000143543.10738.939001090.13900-0.561003.093901.42250K562HNRNPAB
JTBENSG00000143543.10699.51000981.54000-0.488703.937403.24050K562HNRNPC
JTBENSG00000143543.101261.35860887.389500.507202.471901.59460K562HNRNPM
JTBENSG00000143543.10991.351001462.37950-0.560802.752601.95960K562HSPD1
JTBENSG00000143543.10529.25450726.74410-0.457503.240901.62940K562KHDRBS1
JTBENSG00000143543.10631.68420996.08250-0.657105.509603.29560K562LIN28B
JTBENSG00000143543.102119.883601630.553900.378503.611202.33010K562MAK16
JTBENSG00000143543.102300.639001908.259400.269702.229701.42740K562MBNL1
JTBENSG00000143543.101192.778301408.89420-0.240202.897902.13680K562NSUN2
JTBENSG00000143543.10722.983001119.24320-0.630503.792202.32230K562PABPC1
JTBENSG00000143543.101568.872101027.040300.611102.697601.72240K562PABPN1
JTBENSG00000143543.10965.281501372.93600-0.508204.251103.21890K562PCBP3
JTBENSG00000143543.10803.231401053.09530-0.390703.774502.83340K562POLR2G
JTBENSG00000143543.101927.417501224.742800.654108.692007.04060K562PPIG
JTBENSG00000143543.102750.186803244.74420-0.238603.141002.11970K562PUM2
JTBENSG00000143543.102536.874001591.890800.672209.559708.59880K562PUS1
JTBENSG00000143543.102086.751901550.966800.428005.993105.14650K562RBM15
JTBENSG00000143543.101430.758201122.571300.349902.072301.37000K562RPS19
JTBENSG00000143543.101000.108601390.28970-0.475205.422304.30920K562SF3A3
JTBENSG00000143543.10417.56740635.43020-0.605704.039102.85040K562SF3B1
JTBENSG00000143543.10526.53930792.77170-0.590405.341603.55320K562SLBP
JTBENSG00000143543.101030.756601424.38820-0.466608.243406.72500K562SRPK2
JTBENSG00000143543.10800.557001155.21990-0.529103.321201.56380K562TBRG4
JTBENSG00000143543.10881.720501109.52530-0.331502.926602.10020K562U2AF2
JTBENSG00000143543.101007.020601278.26330-0.344102.994002.08460K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for JTB is not available on ENCORE database.





37 RBPs can affect the splicing of JTB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSJTBENSG00000143543.10chr1-153949168153949489153949168153949398153949645153949882-0.097000.000020.00417shorterK562AGGF1
A3SSJTBENSG00000143543.10chr1-153949168153949489153949168153949398153949645153949882-0.122000.000000.00007shorterK562AKAP8L
A3SSJTBENSG00000143543.10chr1-153949168153949489153949168153949398153949645153949882-0.188000.000000.00000shorterK562PUS1
A3SSJTBENSG00000143543.10chr1-153949168153949489153949168153949398153949645153949882-0.120000.000050.01214shorterK562UTP18
A3SSJTBENSG00000143543.10chr1-153949168153949489153949168153949398153949645153949882-0.153000.000000.00000shorterK562RBM15
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.099000.000000.00000excludedK562APOBEC3C
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.125000.000070.00199includedK562SF3B4
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.163000.000000.00000includedK562PUS1
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.172000.000000.00002includedHepG2SF3A3
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.067000.003610.06793excludedK562HNRNPC
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.093000.000000.00000excludedK562EIF4G2
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.082000.000040.00710includedK562NSUN2
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.150000.000000.00007includedHepG2U2AF2
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.082000.000070.01296includedK562SMNDC1
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.184000.000010.00030includedHepG2PRPF8
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.136000.000950.06842includedHepG2EFTUD2
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.118000.000000.00000includedK562AGGF1
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.071000.007540.07494includedK562PRPF8
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.135000.000030.00061includedHepG2QKI
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.109000.000000.00000includedK562AKAP8L
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.086000.000390.03122includedK562WDR3
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.189000.000000.00000includedK562RBM15
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.093000.000000.00001excludedK562EIF3G
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.210000.000000.00001includedK562U2AF1
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.288000.000000.00000includedK562U2AF2
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.068000.000020.01053excludedK562PUM2
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.082000.000070.00160includedK562UTP18
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.193000.000000.00000includedK562EFTUD2
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.062000.000080.01693excludedK562PUM1
RIJTBENSG00000143543.10chr1-1539491681539494891539491681539492511539494511539494890.162000.000000.00000includedK562AQR
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.116000.000000.00000excludedK562PTBP1
RIJTBENSG00000143543.10chr1-153949168153949489153949168153949251153949451153949489-0.096000.000010.00048excludedK562FXR1
MXEJTBENSG00000143543.10chr1-1539483011539483811539491681539492511539467441539473111539494511539494890.130000.000300.067421includedK562KHDRBS1
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539483011539483811539496451539501640.093000.004140.089881includedK562UCHL5
MXEJTBENSG00000143543.10chr1-153948301153948381153949168153949251153946744153947311153949451153949489-0.116000.000300.007942includedK562PUS1
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539483011539483811539496451539501640.114000.001100.035931includedK562XRN2
MXEJTBENSG00000143543.10chr1-153949168153949251153949451153949489153948292153948381153949645153949865-0.117000.000680.027672includedHepG2TAF15
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539483011539483811539496451539501640.103000.001350.088911includedK562NONO
MXEJTBENSG00000143543.10chr1-153948301153948381153949168153949251153946744153947311153949451153949489-0.064000.015500.089892includedK562AQR
MXEJTBENSG00000143543.10chr1-153949168153949251153949451153949489153948292153948381153949645153949865-0.063000.004160.048492includedK562U2AF2
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539482921539483811539496451539498650.116000.000010.000761includedK562TARDBP
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539482921539483811539496451539498650.270000.003250.035571includedHepG2SFPQ
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539482921539483811539496451539498650.096000.000440.035981includedK562TRA2A
MXEJTBENSG00000143543.10chr1-1539483011539483811539491681539492511539467441539473111539494511539494890.171000.001210.074651includedK562RBFOX2
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539483011539483811539496451539501640.089000.001120.045101includedK562HNRNPU
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539483011539483811539496451539501640.084000.001060.050131includedK562TIA1
MXEJTBENSG00000143543.10chr1-1539483011539483811539491681539492511539467441539473111539494511539494890.186000.000000.000331includedK562DHX30
MXEJTBENSG00000143543.10chr1-1539491681539492511539494511539494891539483011539483811539496451539501640.109000.000060.004951includedK562IGF2BP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for JTB is not avaliable on ENCORE database.