ISOC2

General Information

Gene Name       : ISOC2
Gene ID             : ENSG00000063241.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ISOC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ISOC2ENSG00000063241.72.9416.429.68ENCSR000AEF
HepG2ISOC2ENSG00000063241.764.7317.4741.10ENCSR985KAT
K562ISOC2ENSG00000063241.784.6835.5060.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ISOC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ISOC2 RNA is bound by 11 proteins.  







eCLIP assay for ISOC2 is not avaliable on ENCORE database.





11 proteins are bound to ISOC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195596436755964437-3'-UTR,intron-Distal4.9826113.02031K562UPF1
chr195596436855964554-3'-UTR,intron-Distal4.557315.85041HepG2AKAP1
chr195596441055964508-3'-UTR,intron-Distal3.910237.03532HepG2UPF1
chr195596780955967857-3'-UTR,CDS,intron-Distal,intron-Proximal3.8386410.11483K562DDX3X
chr195596436955964416-3'-UTR,intron-Distal4.270828.50867K562PABPC4
chr195596443755964538-3'-UTR,intron-Distal4.6994310.99442K562UPF1
chr195596459255964643-3'-UTR,intron-Distal3.238657.19943K562YBX3
chr195596773655967857-3'-UTR,CDS,intron-Distal,intron-Proximal3.906607.91814HepG2DDX3X
chr195596437055964420-3'-UTR,intron-Distal3.282973.01032HepG2LARP4
chr195596460255964755-3'-UTR,CDS,intron-Distal4.9065519.57800HepG2LARP4
chr195596455455964698-3'-UTR,CDS,intron-Distal3.015323.20150HepG2AKAP1
chr195596452955964666-3'-UTR,intron-Distal4.428494.68979HepG2UPF1
chr195596442055964498-3'-UTR,intron-Distal3.482253.01032HepG2LARP4
chr195597290455972982-5'-UTR,intron-Distal,intron-Proximal6.3886116.92762HepG2DDX3X
chr195597287755972904-5'-UTR,intron-Distal5.105274.66990HepG2DDX3X
chr195597293155973004-5'-UTR,intron-Distal,intron-Proximal3.539539.54233K562PABPC4
chr195597287755972945-5'-UTR,intron-Distal,intron-Proximal4.5045617.48324K562DDX3X
chr195597294555973006-5'-UTR,intron-Distal,intron-Proximal6.0469818.35064K562DDX3X
chr195596718355967212-CDS,intron-Distal,intron-Proximal3.012753.50044K562YBX3
chr195596473055964746-CDS,intron-Distal3.078275.58482K562YBX3
chr195596774555967843-CDS,intron-Distal3.097275.40972K562PABPC4
chr195596635755966436-CDS,intron-Distal,intron-Proximal3.245976.69895HepG2LARP4
chr195596774755967819-CDS,intron-Distal3.478059.92538K562YBX3
chr195596695055967033-CDS,intron-Distal,intron-Proximal4.513029.61639HepG2PRPF8
chr195596672455966906-CDS,intron-Distal,intron-Proximal4.914386.20726K562HNRNPK
chr195596771755967809-CDS,intron-Distal3.070445.85620K562DDX3X
chr195596771455967745-CDS,intron-Distal,intron-Proximal3.929066.92152K562PABPC4
chr195596771455967747-CDS,intron-Distal,intron-Proximal4.966298.97367K562YBX3
chr195596645855966474-CDS,intron-Distal,intron-Proximal3.800253.15159HepG2LARP4
chr195596660055966726-CDS,intron-Distal,intron-Proximal3.503713.39477K562BUD13
chr195596662655966701-CDS,intron-Distal,intron-Proximal4.977257.26512HepG2LARP4
chr195596767955967747-CDS,intron-Distal,intron-Proximal3.013065.24055HepG2PRPF8
chr195596631455966360-CDS,intron-Distal,intron-Proximal4.623634.13847K562AQR
chr195597231955972390-intron-Distal4.520413.23168HepG2DDX59
chr195597280655972878-intron-Distal5.374888.34710K562AQR
chr195597231755972430-intron-Distal4.211384.33150K562HNRNPK
chr195596675655966955-intron-Distal,intron-Proximal4.6345110.43576HepG2HNRNPK
chr195597220055972276-intron-Distal4.466614.83379HepG2HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ISOC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ISOC2 is not available on ENCORE database.

  • 98 RBPs can affect the levels of ISOC2.  








The Knockdown/knockout RNA-Seq assay for ISOC2 is not available on ENCORE database.





98 RBPs can affect the gene expression of ISOC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ISOC2ENSG00000063241.3121.26600316.28170-1.383003.743502.50670HepG2AATF
ISOC2ENSG00000063241.3523.84840810.08260-0.628909.559208.56810HepG2ACO1
ISOC2ENSG00000063241.3736.731701118.00570-0.601702.958302.41050HepG2AKAP1
ISOC2ENSG00000063241.3241.07520475.87100-0.9811012.1344010.97270HepG2CELF1
ISOC2ENSG00000063241.3780.85130511.717800.609608.799207.59180HepG2DAZAP1
ISOC2ENSG00000063241.31385.837101070.798000.372002.424001.83450HepG2DDX3X
ISOC2ENSG00000063241.391.05630420.58130-2.207605.474104.11390HepG2DDX59
ISOC2ENSG00000063241.3497.24680313.762300.664207.805706.78170HepG2DNAJC2
ISOC2ENSG00000063241.3422.11180951.61800-1.172805.809504.83710HepG2EIF4B
ISOC2ENSG00000063241.3719.87240483.578800.573904.590803.55870HepG2EIF4G2
ISOC2ENSG00000063241.3696.147101193.99640-0.7783016.1990014.94190HepG2ETF1
ISOC2ENSG00000063241.3468.63410311.592500.588704.298402.81520HepG2FAM120A
ISOC2ENSG00000063241.3532.29800944.75890-0.827702.920902.13020HepG2FIP1L1
ISOC2ENSG00000063241.3505.24960914.66960-0.856305.340004.42920HepG2G3BP1
ISOC2ENSG00000063241.3609.54360971.43150-0.672403.688402.65120HepG2G3BP2
ISOC2ENSG00000063241.3363.27620218.701900.732004.023102.35230HepG2HNRNPA0
ISOC2ENSG00000063241.3764.69880459.192300.735707.877906.74630HepG2HNRNPF
ISOC2ENSG00000063241.3608.80970466.147800.385103.298802.56760HepG2HNRNPL
ISOC2ENSG00000063241.3491.63310353.128600.477304.161103.42980HepG2HNRNPU
ISOC2ENSG00000063241.3894.70290452.162500.984506.052205.02310HepG2IGF2BP1
ISOC2ENSG00000063241.3537.09950360.708800.574306.523805.44570HepG2ILF2
ISOC2ENSG00000063241.31306.74800986.681500.405202.667002.02300HepG2MAGOH
ISOC2ENSG00000063241.3422.41020764.20170-0.855305.253804.16660HepG2MSI2
ISOC2ENSG00000063241.3402.85510271.957700.566803.081901.58950HepG2NIP7
ISOC2ENSG00000063241.3757.50510332.899801.186105.527403.53280HepG2NOLC1
ISOC2ENSG00000063241.3379.16500236.205600.682702.600901.74690HepG2PABPC1
ISOC2ENSG00000063241.3261.93710349.53370-0.416202.435901.63680HepG2PARN
ISOC2ENSG00000063241.3413.27210288.219200.519803.412302.04540HepG2PKM
ISOC2ENSG00000063241.3501.71610314.962100.671606.805705.69080HepG2PPIL4
ISOC2ENSG00000063241.3636.52310979.73960-0.622209.333708.44620HepG2PTBP1
ISOC2ENSG00000063241.3883.08650484.362200.8664011.4252010.32490HepG2PUF60
ISOC2ENSG00000063241.3691.667501061.06930-0.617408.193307.20680HepG2QKI
ISOC2ENSG00000063241.3145.50700327.33300-1.169702.406001.74560HepG2RAVER1
ISOC2ENSG00000063241.3574.63680883.42400-0.620507.438506.12700HepG2RBM15
ISOC2ENSG00000063241.3833.42160997.95640-0.259902.003301.54370HepG2RBM22
ISOC2ENSG00000063241.3712.21850962.99350-0.435202.628601.96890HepG2RBM25
ISOC2ENSG00000063241.3592.68460362.742200.708204.803803.47760HepG2RBM27
ISOC2ENSG00000063241.3562.43810294.564800.933006.539904.90270HepG2RCC2
ISOC2ENSG00000063241.3511.863201090.35110-1.0910025.1991023.89180HepG2NELFE
ISOC2ENSG00000063241.3574.853501015.52300-0.8210014.3891013.15310HepG2RECQL
ISOC2ENSG00000063241.3497.81650334.505500.573502.197601.48010HepG2RPS2
ISOC2ENSG00000063241.3446.58000259.654400.782204.845003.78420HepG2RPS3A
ISOC2ENSG00000063241.3679.18520314.475201.110809.049807.99040HepG2SAFB2
ISOC2ENSG00000063241.3387.25740244.503300.663303.688202.18160HepG2SART3
ISOC2ENSG00000063241.3390.33030246.527000.662803.071401.43440HepG2SBDS
ISOC2ENSG00000063241.3666.031101020.02460-0.614907.301606.41390HepG2SF3B4
ISOC2ENSG00000063241.3807.84390464.401300.798609.940708.73880HepG2SLBP
ISOC2ENSG00000063241.3647.17770334.908400.950305.190203.85310HepG2SMNDC1
ISOC2ENSG00000063241.3207.81980441.13180-1.085902.766601.98570HepG2SNRNP70
ISOC2ENSG00000063241.3715.940101127.14850-0.6548011.5517010.71740HepG2SRFBP1
ISOC2ENSG00000063241.3505.070301064.68920-1.0759025.0886023.97600HepG2SRSF1
ISOC2ENSG00000063241.3684.63630478.221600.517605.498504.65960HepG2SRSF5
ISOC2ENSG00000063241.3766.25930451.178900.764007.679406.61540HepG2SRSF7
ISOC2ENSG00000063241.3300.47110866.18520-1.5274042.5929040.93500HepG2SRSF9
ISOC2ENSG00000063241.3843.73110978.62040-0.214001.742101.31210HepG2SSB
ISOC2ENSG00000063241.3281.67360956.99650-1.7645048.5920046.61700HepG2TAF15
ISOC2ENSG00000063241.3473.78040879.33640-0.8922013.6627011.84460HepG2TIA1
ISOC2ENSG00000063241.3445.64410343.120800.377102.192101.73690HepG2TIAL1
ISOC2ENSG00000063241.3602.62800346.198400.7996011.2702010.24560HepG2TRIM56
ISOC2ENSG00000063241.3792.02010473.180300.743003.850702.80090HepG2TUFM
ISOC2ENSG00000063241.3526.76590744.28570-0.498704.046003.34150HepG2UTP3
ISOC2ENSG00000063241.3437.69650232.586200.912106.416404.74930HepG2XPO5
ISOC2ENSG00000063241.3558.22590714.35940-0.355802.083801.48800HepG2ZC3H8
ISOC2ENSG00000063241.3599.83210847.85670-0.499304.008703.38320HepG2ZNF622
ISOC2ENSG00000063241.31391.50520870.255900.6770013.9272012.75710K562AGGF1
ISOC2ENSG00000063241.3757.09110591.816200.355203.165701.53250K562AKAP1
ISOC2ENSG00000063241.31391.81050956.310200.541304.335503.04470K562AKAP8
ISOC2ENSG00000063241.31771.00080905.548300.967603.497602.75920K562AKAP8L
ISOC2ENSG00000063241.3850.149401284.55360-0.595505.954205.15040K562AQR
ISOC2ENSG00000063241.31407.23210950.152300.566509.087907.30870K562ATP5C1
ISOC2ENSG00000063241.3805.44950490.901300.714305.809104.40300K562BCLAF1
ISOC2ENSG00000063241.31004.51510705.671400.509302.284701.34330K562CCAR1
ISOC2ENSG00000063241.31260.760701039.979200.277602.392401.31100K562CCDC124
ISOC2ENSG00000063241.3638.02110918.09740-0.525003.273801.62310K562CEBPZ
ISOC2ENSG00000063241.31453.137001062.213400.452003.317502.09770K562CPEB4
ISOC2ENSG00000063241.31056.435201723.66430-0.706304.451803.20440K562CELF1
ISOC2ENSG00000063241.3956.93550607.959400.654309.532906.82530K562DDX6
ISOC2ENSG00000063241.31181.66030974.387800.278102.720401.85510K562DKC1
ISOC2ENSG00000063241.3327.68510191.422400.775505.479504.37290K562EIF3G
ISOC2ENSG00000063241.3792.10220564.169900.489505.268103.60160K562EIF4B
ISOC2ENSG00000063241.31130.45540750.239700.591405.878604.60920K562FIP1L1
ISOC2ENSG00000063241.3254.02720504.41620-0.989603.213801.98290K562FKBP4
ISOC2ENSG00000063241.3810.26960651.508600.314502.545301.95950K562FXR1
ISOC2ENSG00000063241.321.64640153.77900-2.8287018.1877015.93780K562G3BP2
ISOC2ENSG00000063241.31422.967501017.042500.484402.320901.58750K562HSPD1
ISOC2ENSG00000063241.3718.41510299.316401.263003.882002.58250K562IGF2BP2
ISOC2ENSG00000063241.3547.09200314.186700.800105.488904.29040K562MAGOH
ISOC2ENSG00000063241.31225.66240919.922100.413903.521402.26200K562MAK16
ISOC2ENSG00000063241.31637.864701076.551500.605309.211607.36040K562MBNL1
ISOC2ENSG00000063241.3729.29050394.179800.887504.824802.98110K562NONO
ISOC2ENSG00000063241.31075.550101252.27750-0.219502.366401.67210K562NSUN2
ISOC2ENSG00000063241.31154.75360735.930000.649802.751401.76430K562PABPN1
ISOC2ENSG00000063241.31804.46460851.797201.082909.297007.55560K562PPIG
ISOC2ENSG00000063241.3568.57880305.280700.897106.533405.54600K562PTBP1
ISOC2ENSG00000063241.31185.825901626.77130-0.456102.602201.56910K562PUM1
ISOC2ENSG00000063241.31246.11930898.001800.472603.218502.64060K562PUS1
ISOC2ENSG00000063241.31324.09710875.011900.597509.267208.20470K562RBM15
ISOC2ENSG00000063241.3839.50440474.830200.822007.829706.16110K562RCC2
ISOC2ENSG00000063241.31248.10990780.215000.677704.085702.76050K562SAFB
ISOC2ENSG00000063241.3939.744601235.69850-0.395002.110701.39190K562SF3A3
ISOC2ENSG00000063241.3905.57320450.089801.0085012.078209.53010K562SRFBP1
ISOC2ENSG00000063241.3473.61630299.319800.661903.216902.45970K562SRSF1
ISOC2ENSG00000063241.3839.11060315.622301.410607.372505.52610K562SRSF4
ISOC2ENSG00000063241.3509.53380282.791500.849305.492203.92180K562SRSF5
ISOC2ENSG00000063241.356.26370150.95130-1.423803.213801.59710K562TAF15
ISOC2ENSG00000063241.3574.46940302.838500.923605.863504.80730K562TARDBP
ISOC2ENSG00000063241.3683.26420292.146301.2257017.2780015.08310K562TIA1
ISOC2ENSG00000063241.3540.59560286.901800.913905.386303.74560K562TRA2A
ISOC2ENSG00000063241.3927.28290531.746400.802205.930804.42910K562TRIM56
ISOC2ENSG00000063241.361.32840153.94020-1.327707.632406.29290K562U2AF2
ISOC2ENSG00000063241.3919.473601136.16970-0.305302.369301.55730K562WDR3
ISOC2ENSG00000063241.3909.343201181.49670-0.377705.170504.04460K562WDR43
ISOC2ENSG00000063241.3677.08010405.708300.738803.385002.00430K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ISOC2 is not available on ENCORE database.





13 RBPs can affect the splicing of ISOC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.249000.005010.07592excludedK562SRSF1
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.395000.000000.00005excludedHepG2U2AF1
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.293000.009460.08728excludedHepG2U2AF2
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.200000.001260.04713excludedK562FXR1
SEISOC2ENSG00000063241.3chr19-5596700255967212559666265596674555967715559678560.181000.002040.08816includedHepG2PTBP1
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559667455596771555967856-0.343000.003650.06389excludedK562U2AF1
SEISOC2ENSG00000063241.3chr19-5596700255967212559666265596669755967715559678560.194000.000640.01768includedHepG2SRSF1
SEISOC2ENSG00000063241.3chr19-5596700255967212559666265596669755967715559678560.189000.000000.00048includedHepG2SSB
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.255000.000000.00005excludedHepG2PCBP1
SEISOC2ENSG00000063241.3chr19-5596700255967212559666265596669755967715559678560.278000.000000.00395includedHepG2NOL12
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.227000.000010.00125excludedHepG2SF3B4
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559667455596771555967856-0.275000.000220.05521excludedHepG2FUBP3
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.374000.000000.00011excludedHepG2SRSF9
SEISOC2ENSG00000063241.3chr19-559670025596721255966626559666975596771555967856-0.248000.001290.02388excludedK562HNRNPC
A3SSISOC2ENSG00000063241.3chr19-559666265596674555966626559666975596700255967212-0.269000.000120.09384shorterHepG2NOL12
A3SSISOC2ENSG00000063241.3chr19-5596662655966745559666265596669755967002559672120.291000.001350.03394longerHepG2U2AF2
A3SSISOC2ENSG00000063241.3chr19-5596662655966745559666265596669755967002559672120.115000.003740.02236longerK562AQR
A3SSISOC2ENSG00000063241.3chr19-5596662655966745559666265596669755967002559672120.331000.000040.00857longerK562HNRNPC
A3SSISOC2ENSG00000063241.3chr19-559666265596674555966626559666975596771555967856-0.203000.000030.00734shorterHepG2PCBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ISOC2 is not avaliable on ENCORE database.