HECTD3

General Information

Gene Name       : HECTD3
Gene ID             : ENSG00000126107.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HECTD3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HECTD3ENSG00000126107.1413.0614.9714.02ENCSR000AEF
HepG2HECTD3ENSG00000126107.1420.2314.1117.17ENCSR985KAT
K562HECTD3ENSG00000126107.1430.4629.5129.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HECTD3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HECTD3 RNA is bound by 16 proteins.  







eCLIP assay for HECTD3 is not avaliable on ENCORE database.





16 proteins are bound to HECTD3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14546826545468312-3'-UTR,intron-Distal3.538906.37005K562UPF1
chr14546827645468384-3'-UTR,intron-Distal3.821295.89669K562HNRNPK
chr14546868145468816-3'-UTR,intron-Distal3.161426.98442K562IGF2BP1
chr14546875645468797-3'-UTR,intron-Distal3.695865.21358K562TIA1
chr14546867945468811-3'-UTR,intron-Distal3.8670718.54601K562UPF1
chr14546853145468589-3'-UTR,intron-Distal3.857583.22721K562YBX3
chr14546876645468804-3'-UTR,intron-Distal5.054055.39854K562PTBP1
chr14546827745468324-3'-UTR,intron-Distal5.084414.57427HepG2PCBP2
chr14546866645468804-3'-UTR,intron-Distal4.997247.98718HepG2UPF1
chr14546867845468760-3'-UTR,intron-Distal3.234803.34573K562IGF2BP2
chr14546826045468352-3'-UTR,intron-Distal3.152254.00349K562FAM120A
chr14546833445468427-3'-UTR,intron-Distal3.9316710.92054K562UPF1
chr14546825345468299-3'-UTR,intron-Distal4.206664.21358HepG2U2AF2
chr14546841545468493-3'-UTR,intron-Distal4.0778110.01488HepG2PCBP2
chr14546992745469986-CDS,intron-Distal4.289333.71613K562UCHL5
chr14547482845474879-CDS,intron-Distal3.718565.14848K562ZNF622
chr14547027045470346-CDS,intron-Distal,intron-Proximal3.922863.39325K562SRSF1
chr14547027145470354-CDS,intron-Distal,intron-Proximal4.587265.29868K562UCHL5
chr14547482745474884-CDS,intron-Distal4.173683.49905HepG2PPIG
chr14547498345475043-CDS,intron-Distal,intron-Proximal4.103883.86479HepG2PRPF8
chr14547515845475204-intron-Distal,intron-Proximal4.939614.24111K562EFTUD2
chr14547558545475652-intron-Distal,intron-Proximal3.554954.58287K562PRPF8
chr14547103345471169-intron-Distal4.369944.80949K562HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HECTD3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HECTD3 is not available on ENCORE database.

  • 93 RBPs can affect the levels of HECTD3.  








The Knockdown/knockout RNA-Seq assay for HECTD3 is not available on ENCORE database.





93 RBPs can affect the gene expression of HECTD3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HECTD3ENSG00000126107.10820.31590687.652800.254402.127101.57960HepG2ACO1
HECTD3ENSG00000126107.101053.06820690.764500.608209.773408.43850HepG2AKAP8L
HECTD3ENSG00000126107.10906.97840678.404900.418802.777301.99180HepG2ASCC1
HECTD3ENSG00000126107.101186.06780964.839000.297703.085202.36610HepG2AUH
HECTD3ENSG00000126107.101684.36440985.380200.773405.657304.83840HepG2BOP1
HECTD3ENSG00000126107.101079.55710755.448800.514904.856803.24560HepG2BUD13
HECTD3ENSG00000126107.10861.25390680.643400.339402.623101.87150HepG2CALR
HECTD3ENSG00000126107.101321.74040644.535701.0360015.3834013.73200HepG2CIRBP
HECTD3ENSG00000126107.10992.81980687.360100.530407.653106.65230HepG2CKAP4
HECTD3ENSG00000126107.101136.39340753.266700.593107.162306.21980HepG2CELF1
HECTD3ENSG00000126107.10957.43820809.797800.241502.591401.86930HepG2DAZAP1
HECTD3ENSG00000126107.10770.76130511.438100.591603.890402.53230HepG2DDX1
HECTD3ENSG00000126107.10730.28910512.019300.512204.095003.28530HepG2DDX21
HECTD3ENSG00000126107.101592.42390785.396401.0196014.8533013.51820HepG2DDX3X
HECTD3ENSG00000126107.101022.89910587.519200.799906.073304.98120HepG2DDX55
HECTD3ENSG00000126107.101887.104401027.309000.877206.232104.79510HepG2DDX59
HECTD3ENSG00000126107.101209.77150838.244000.529205.040103.70660HepG2DDX5
HECTD3ENSG00000126107.101047.15200674.739800.634005.199204.37770HepG2DDX6
HECTD3ENSG00000126107.101052.50210657.860300.6779011.3608010.18260HepG2DKC1
HECTD3ENSG00000126107.10655.98040497.168200.399801.895701.33740HepG2DNAJC2
HECTD3ENSG00000126107.10739.56450487.029300.602604.533203.37830HepG2EEF2
HECTD3ENSG00000126107.10544.59360405.965000.423702.392301.36310HepG2EFTUD2
HECTD3ENSG00000126107.101049.33180648.576200.694006.736805.83800HepG2EIF2S1
HECTD3ENSG00000126107.10592.31060395.331000.583203.508302.49690HepG2EIF3D
HECTD3ENSG00000126107.101245.12790716.720200.796708.113007.02210HepG2EIF4A3
HECTD3ENSG00000126107.101562.544101107.785000.496108.014907.08300HepG2ETF1
HECTD3ENSG00000126107.101322.808601018.384000.377202.094001.42010HepG2FIP1L1
HECTD3ENSG00000126107.10784.23740549.577000.512902.842201.71350HepG2FUS
HECTD3ENSG00000126107.101082.61310723.239600.581905.082404.16480HepG2FXR1
HECTD3ENSG00000126107.10551.73180351.982900.648405.043603.83170HepG2GEMIN5
HECTD3ENSG00000126107.101399.852701025.626100.448703.344302.64480HepG2GPKOW
HECTD3ENSG00000126107.10844.88650656.424700.364003.770002.64350HepG2HDGF
HECTD3ENSG00000126107.10932.38800744.299200.324903.204802.20900HepG2HNRNPA2B1
HECTD3ENSG00000126107.10961.92130679.426800.501504.109403.27230HepG2HNRNPK
HECTD3ENSG00000126107.101842.40540978.764000.9125012.4909011.27940HepG2HNRNPLL
HECTD3ENSG00000126107.101678.07670681.894801.2991024.4424022.68610HepG2IGF2BP2
HECTD3ENSG00000126107.101349.016701010.393900.416902.517801.72670HepG2LARP4
HECTD3ENSG00000126107.101017.25510723.492600.491503.681602.92590HepG2MAGOH
HECTD3ENSG00000126107.101254.35420823.965900.606206.835005.61930HepG2MSI2
HECTD3ENSG00000126107.101522.68300744.650001.0319014.4878013.11240HepG2NCBP2
HECTD3ENSG00000126107.10512.22170842.18040-0.717405.173003.21710HepG2NKRF
HECTD3ENSG00000126107.10978.57650663.099300.561404.568803.65280HepG2PABPC4
HECTD3ENSG00000126107.10501.36630721.79320-0.525706.073604.97550HepG2PRPF4
HECTD3ENSG00000126107.101002.06390716.646300.483504.731204.05820HepG2PTBP1
HECTD3ENSG00000126107.101147.39360766.576700.581806.989406.09820HepG2PUF60
HECTD3ENSG00000126107.101072.19450813.178900.398804.133403.32100HepG2PUM2
HECTD3ENSG00000126107.101389.22560700.398000.9879029.4246027.80310HepG2PUS1
HECTD3ENSG00000126107.10956.37900776.012100.301402.502201.90300HepG2QKI
HECTD3ENSG00000126107.10767.50750501.825600.612902.944502.21870HepG2RAVER1
HECTD3ENSG00000126107.101415.480601034.901100.451705.043303.92860HepG2RBM15
HECTD3ENSG00000126107.101155.85300925.899000.319903.084802.54590HepG2RBM22
HECTD3ENSG00000126107.101450.37080918.966400.658207.847406.78810HepG2RPLP0
HECTD3ENSG00000126107.10627.40910384.703600.705606.784205.86950HepG2RPS19
HECTD3ENSG00000126107.10791.23060575.684200.458702.895302.07900HepG2RPS2
HECTD3ENSG00000126107.10668.17380498.190400.423402.517201.89790HepG2SAFB2
HECTD3ENSG00000126107.10601.45590386.064000.639504.943203.69780HepG2SERBP1
HECTD3ENSG00000126107.101511.22670933.108700.695505.620704.63920HepG2SF3A3
HECTD3ENSG00000126107.101011.36830756.940700.418005.499404.66050HepG2SRSF5
HECTD3ENSG00000126107.101249.36360907.954900.460406.932006.19060HepG2SSB
HECTD3ENSG00000126107.101123.61310860.800600.384304.689903.91730HepG2SUCLG1
HECTD3ENSG00000126107.10818.92660584.825500.485602.626001.96500HepG2SUPV3L1
HECTD3ENSG00000126107.101645.13640953.702300.786504.642303.73610HepG2TARDBP
HECTD3ENSG00000126107.101089.05310543.449801.0028013.3309012.37290HepG2TIAL1
HECTD3ENSG00000126107.10797.01170548.481000.539104.192603.52680HepG2TRIM56
HECTD3ENSG00000126107.101096.77720616.191100.831702.249801.37040HepG2U2AF2
HECTD3ENSG00000126107.101233.28370792.847900.637305.848404.60030HepG2UBE2L3
HECTD3ENSG00000126107.101224.01600827.525300.5646010.132808.94340HepG2UPF1
HECTD3ENSG00000126107.101090.19500850.575900.358003.552702.38200HepG2UTP18
HECTD3ENSG00000126107.102267.41910910.118601.3168074.4890072.66680HepG2ZNF622
HECTD3ENSG00000126107.102440.971102115.737800.206202.423601.88700K562AGGF1
HECTD3ENSG00000126107.101744.567202435.81070-0.481505.394404.62190K562AQR
HECTD3ENSG00000126107.101274.943101016.467000.326803.878901.39950K562ASCC1
HECTD3ENSG00000126107.103250.766501985.385600.7113010.425908.68170K562BOP1
HECTD3ENSG00000126107.103070.577002528.401500.280203.007901.77110K562CCDC124
HECTD3ENSG00000126107.101577.685101182.700800.415603.839902.31870K562CIRBP
HECTD3ENSG00000126107.101343.414101086.203800.306503.400201.91830K562DDX27
HECTD3ENSG00000126107.101390.815001054.022500.399904.125202.81760K562DDX3X
HECTD3ENSG00000126107.102913.567802485.021000.229402.863402.20080K562DDX47
HECTD3ENSG00000126107.102002.218302368.96040-0.242702.515001.68390K562DKC1
HECTD3ENSG00000126107.101676.890601245.606200.428802.574101.34390K562EEF2
HECTD3ENSG00000126107.101453.699101157.812100.328204.096502.60570K562EIF2S1
HECTD3ENSG00000126107.101397.306201782.89210-0.351604.470903.58440K562EIF2S2
HECTD3ENSG00000126107.101156.03940855.988100.433404.649003.62870K562EIF3G
HECTD3ENSG00000126107.102366.641702870.09460-0.278303.498902.44430K562EIF4G2
HECTD3ENSG00000126107.101491.432301145.221600.381004.067003.35450K562FXR1
HECTD3ENSG00000126107.10350.61740695.57870-0.988306.764205.55150K562G3BP2
HECTD3ENSG00000126107.101668.126301984.63200-0.250602.466001.39440K562GLRX3
HECTD3ENSG00000126107.102654.566302015.648300.397104.238203.26100K562GPKOW
HECTD3ENSG00000126107.101321.353701749.81760-0.405202.762501.69110K562HNRNPA1
HECTD3ENSG00000126107.101710.788101104.088300.631705.819004.09880K562IGF2BP2
HECTD3ENSG00000126107.101445.440901122.768700.364303.132001.84540K562IGF2BP3
HECTD3ENSG00000126107.101730.862801350.879500.357503.232401.70330K562LARP7
HECTD3ENSG00000126107.101367.522401099.599600.314502.876901.62280K562NCBP2
HECTD3ENSG00000126107.10646.521601301.46660-1.009406.328803.21940K562NFX1
HECTD3ENSG00000126107.102571.955902318.315500.149701.981201.33650K562NSUN2
HECTD3ENSG00000126107.102284.676601126.826801.0196025.3686023.44000K562PTBP1
HECTD3ENSG00000126107.102710.834303330.82960-0.297103.351402.17290K562PUM1
HECTD3ENSG00000126107.102464.462303263.55490-0.405206.807705.28300K562PUM2
HECTD3ENSG00000126107.104233.452602183.264700.955206.010905.24770K562PUS1
HECTD3ENSG00000126107.102443.158702127.301200.199601.873301.36840K562RBM15
HECTD3ENSG00000126107.102781.327702253.055100.303802.997801.32460K562RBM17
HECTD3ENSG00000126107.101369.27690954.701700.520203.008001.95950K562RPS3
HECTD3ENSG00000126107.102061.799001687.246200.289102.475001.45420K562SAFB
HECTD3ENSG00000126107.101691.851101104.732100.614809.025007.75640K562SRSF1
HECTD3ENSG00000126107.101908.916002593.56890-0.442202.660901.33390K562SSRP1
HECTD3ENSG00000126107.101584.128301133.516400.482803.822302.61400K562SUPV3L1
HECTD3ENSG00000126107.101780.153501117.918300.671107.633906.39010K562TARDBP
HECTD3ENSG00000126107.101477.757101078.395900.454405.100103.93720K562TIA1
HECTD3ENSG00000126107.101703.900001203.172000.501904.607803.37660K562TIAL1
HECTD3ENSG00000126107.101417.560501058.565000.421203.780302.47050K562TRA2A
HECTD3ENSG00000126107.10459.54890673.64780-0.551802.987501.84480K562U2AF1
HECTD3ENSG00000126107.103144.825502458.165400.355306.838805.76540K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HECTD3 is not available on ENCORE database.





25 RBPs can affect the splicing of HECTD3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHECTD3ENSG00000126107.10chr1-454714654547155545470271454704784547166845471896-0.079000.000490.01160excludedK562SRSF1
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.161000.000000.00009excludedK562PRPF8
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.308000.000040.00133excludedHepG2U2AF1
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.304000.000950.01358excludedHepG2U2AF2
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.129000.000000.00001excludedK562AQR
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.078000.001350.09150excludedK562SUPV3L1
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.113000.000050.00520excludedK562EFTUD2
SEHECTD3ENSG00000126107.10chr1-454714654547155545470271454704784547166845471788-0.065000.001060.06603excludedK562HNRNPL
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.088000.003020.04851excludedK562U2AF2
SEHECTD3ENSG00000126107.10chr1-454756574547579345475239454753554547587245475965-0.193000.000040.00122excludedK562HNRNPC
A3SSHECTD3ENSG00000126107.10chr1-4547289045472988454728904547294345473084454732340.081000.000040.00035longerK562AQR
A3SSHECTD3ENSG00000126107.10chr1-4546991945470118454699194547004945470271454705150.101000.000000.00000longerK562AQR
A3SSHECTD3ENSG00000126107.10chr1-4547174445471805454717444547178845472363454724670.084000.000080.00071longerK562AQR
A3SSHECTD3ENSG00000126107.10chr1-4547481545474956454748154547489845475040454751540.109000.000000.00000longerK562AQR
A3SSHECTD3ENSG00000126107.10chr1-4547027145470508454702714547047845471465454715250.159000.000000.00000longerK562AQR
A3SSHECTD3ENSG00000126107.10chr1-4547391145474011454739114547399345474207454743730.173000.000000.00004longerK562AQR
A5SSHECTD3ENSG00000126107.10chr1-454714654547178845471668454717884547027145470478-0.114000.000520.03329shorterK562SRSF1
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.286000.000140.00351includedK562SF3B4
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.286000.000320.00861includedHepG2PCBP2
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.105000.000180.00154includedK562PUS1
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.256000.000280.00470includedHepG2SF3A3
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.495000.000000.00000includedHepG2PRPF8
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.350000.000000.00000includedK562PRPF8
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.148000.000400.01174includedHepG2IGF2BP3
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.181000.000010.00100includedHepG2MATR3
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.286000.000020.00245includedHepG2HNRNPA1
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.138000.000130.00194includedK562AKAP8L
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.092000.011560.09468includedK562RBM15
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.113000.001410.02629includedHepG2G3BP1
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.143000.000200.00685includedHepG2KHSRP
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.363000.000000.00007includedHepG2TIAL1
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.079000.011200.09346includedHepG2NCBP2
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.241000.000150.00189includedHepG2SF3B4
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.150000.001870.03308includedHepG2FUBP3
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.161000.000040.00080includedHepG2HNRNPK
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.117000.000810.01213includedK562UTP18
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.347000.000000.00000includedK562EFTUD2
RIHECTD3ENSG00000126107.10chr1-4547146545471788454714654547155545471668454717880.330000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HECTD3 is not avaliable on ENCORE database.