ARL8B

General Information

Gene Name       : ARL8B
Gene ID             : ENSG00000134108.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ARL8B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ARL8BENSG00000134108.1258.1846.9652.57ENCSR000AEF
HepG2ARL8BENSG00000134108.1216.3630.9523.66ENCSR985KAT
K562ARL8BENSG00000134108.1257.2466.8762.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ARL8B is not avaliable on ENCORE database.



Proteins bound to RNA
  • ARL8B RNA is bound by 27 proteins.  







eCLIP assay for ARL8B is not avaliable on ENCORE database.





27 proteins are bound to ARL8B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr352216805221753+3'-UTR3.6263712.51607K562PUM2
chr352223025222350+3'-UTR5.3515119.80961K562PUM2
chr352210635221081+3'-UTR4.3753922.59135K562YBX3
chr352160895216175+3'-UTR,CDS,intron-Distal,intron-Proximal4.464709.27995K562PRPF8
chr352121335212266+3'-UTR,CDS,intron-Proximal3.196759.15507K562SF3B4
chr352211565221171+3'-UTR4.540795.54754K562IGF2BP1
chr352211435221223+3'-UTR3.3325728.99422K562UPF1
chr352220055222050+3'-UTR3.9660211.58326K562UPF1
chr352220665222116+3'-UTR3.150917.86167K562YBX3
chr352202885220371+3'-UTR,CDS,intron-Proximal4.435279.23765K562SF3B4
chr352138285213905+3'-UTR,CDS,intron-Distal,intron-Proximal4.9072710.39791K562U2AF2
chr352210555221063+3'-UTR5.1314410.65788K562YBX3
chr352221375222198+3'-UTR5.2874716.93141K562UPF1
chr352210445221112+3'-UTR3.456194.12796K562LIN28B
chr352210815221115+3'-UTR3.8807012.85041K562YBX3
chr352138375213906+3'-UTR,CDS,intron-Distal3.432156.97987K562ZNF622
chr352207125220732+3'-UTR4.149793.50232K562IGF2BP1
chr352160885216176+3'-UTR,CDS,intron-Distal,intron-Proximal4.0558411.85698K562KHSRP
chr352216545221772+3'-UTR5.8253828.13591K562IGF2BP1
chr352212475221311+3'-UTR3.4896218.28632K562UPF1
chr352223615222406+3'-UTR3.929146.87998K562TIA1
chr352223505222402+3'-UTR5.1842654.69990K562PUM2
chr352204585220500+3'-UTR,CDS4.607524.77152K562IGF2BP1
chr352214605221551+3'-UTR3.3014217.77726K562UPF1
chr352211715221210+3'-UTR4.368049.23779K562IGF2BP1
chr352210635221103+3'-UTR3.154937.14729K562UPF1
chr352206245220670+3'-UTR3.362459.62459K562UPF1
chr352212105221277+3'-UTR3.324927.41930K562IGF2BP1
chr352206315220684+3'-UTR4.594973.50232K562IGF2BP1
chr352210375221055+3'-UTR5.1816110.89067K562YBX3
chr351640535164104+5'-UTR,CDS4.1667712.79258K562DDX3X
chr351639875164105+5'-UTR,CDS5.4361616.67528HepG2DDX3X
chr351640705164135+5'-UTR,CDS3.302674.71868K562GEMIN5
chr351639785164088+5'-UTR,CDS3.311815.03167HepG2NCBP2
chr351639895164053+5'-UTR,CDS4.759569.77030K562DDX3X
chr351641045164154+5'-UTR,CDS3.210775.85428K562DDX3X
chr351641865164233+CDS4.193854.46921K562RBM15
chr351642255164303+CDS,intron-Proximal3.137454.38519K562BUD13
chr352110055211071+intron-Distal5.7802913.16698K562TARDBP
chr352158615215923+intron-Distal,intron-Proximal3.770093.55754HepG2U2AF2
chr351643455164395+intron-Distal,intron-Proximal3.711214.22460K562RBM15
chr351824075182530+intron-Distal3.762824.71513K562NONO
chr351941085194244+intron-Distal3.091273.43500K562MATR3
chr351761375176206+intron-Distal3.758586.40701K562EXOSC5
chr352144985214530+intron-Distal,intron-Proximal4.6603114.59387K562KHSRP
chr352169795217077+intron-Distal3.667993.24603K562KHSRP
chr352145315214614+intron-Distal4.2391313.51632K562KHSRP
chr351867385186804+intron-Distal3.848023.39864HepG2SUGP2
chr352199295219980+intron-Distal3.981444.28548HepG2HNRNPC
chr351882385188344+intron-Distal3.290043.32889K562MATR3
chr351873415187421+intron-Distal3.728783.16028HepG2SUGP2
chr351737665173827+intron-Distal4.056405.93686K562XRCC6
chr352139275214055+intron-Distal,intron-Proximal4.5535412.35151K562AQR
chr351760605176084+intron-Distal4.968493.04182K562HNRNPM
chr351651425165186+intron-Distal3.159024.19308K562EXOSC5
chr351891695189265+intron-Distal4.2638115.21140K562MATR3
chr351891115189169+intron-Distal5.401568.85229K562MATR3
chr351891695189271+intron-Distal4.079007.54890HepG2SUGP2
chr352157965215898+intron-Distal,intron-Proximal5.537816.03057K562EFTUD2
chr351784755178585+intron-Distal4.386094.31871HepG2HNRNPM
chr352099615210016+intron-Distal3.263923.40391K562XRCC6
chr351906245190698+intron-Distal3.637826.70640K562MATR3
chr352158045215941+intron-Distal,intron-Proximal3.137757.78760K562KHSRP
chr352144755214498+intron-Distal,intron-Proximal4.119058.75974K562KHSRP
chr352109965211063+intron-Distal4.137965.99081K562IGF2BP1
chr351918495191914+intron-Distal3.349494.36594K562HNRNPM
chr351917825191898+intron-Distal3.182383.18845HepG2HNRNPM
chr352144995214593+intron-Distal,intron-Proximal3.004594.95232K562PRPF8
chr351891905189263+intron-Distal5.544377.41017K562PTBP1
chr352057865205849+intron-Distal3.396144.10408K562KHSRP
chr352122835212337+intron-Proximal4.611924.23889K562TIA1
chr352122705212332+intron-Proximal4.184883.31283K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ARL8B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ARL8B is not available on ENCORE database.

  • 82 RBPs can affect the levels of ARL8B.  








The Knockdown/knockout RNA-Seq assay for ARL8B is not available on ENCORE database.





82 RBPs can affect the gene expression of ARL8B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ARL8BENSG00000134108.8885.47780688.373700.363202.507201.48260HepG2AATF
ARL8BENSG00000134108.81195.41390985.365700.278703.052102.41800HepG2ACO1
ARL8BENSG00000134108.81248.00300989.924200.334102.526601.78980HepG2AKAP8L
ARL8BENSG00000134108.81794.095801545.914900.214702.176801.55460HepG2AUH
ARL8BENSG00000134108.8986.68440759.559000.377302.824302.14090HepG2DDX21
ARL8BENSG00000134108.8742.75950917.45730-0.304702.606201.91910HepG2DNAJC21
ARL8BENSG00000134108.8709.90070909.39400-0.357304.204803.43270HepG2DNAJC2
ARL8BENSG00000134108.8956.309901367.12150-0.515604.464303.72120HepG2EIF2S1
ARL8BENSG00000134108.8925.26370709.501000.383002.721601.82630HepG2EIF3D
ARL8BENSG00000134108.81162.316201510.82190-0.378302.406001.80860HepG2EIF4A3
ARL8BENSG00000134108.8702.935201334.73690-0.9251014.3222012.57550HepG2EIF4G2
ARL8BENSG00000134108.8991.539201414.07340-0.512104.138903.33460HepG2G3BP1
ARL8BENSG00000134108.81172.474701501.23690-0.356602.538701.68810HepG2G3BP2
ARL8BENSG00000134108.8994.505701272.26450-0.355303.993503.14730HepG2HNRNPF
ARL8BENSG00000134108.8947.147701431.90730-0.596306.437405.40300HepG2HNRNPK
ARL8BENSG00000134108.81003.815401286.67050-0.358105.466704.54710HepG2HNRNPL
ARL8BENSG00000134108.8795.846001023.47880-0.362904.129803.40060HepG2HNRNPU
ARL8BENSG00000134108.8883.875601437.37020-0.701507.728606.65920HepG2IGF2BP2
ARL8BENSG00000134108.8967.860701445.75730-0.579004.275003.00220HepG2KHSRP
ARL8BENSG00000134108.82331.876801724.071400.435602.918402.06530HepG2LARP4
ARL8BENSG00000134108.81150.659601400.56210-0.283502.748801.98720HepG2NOL12
ARL8BENSG00000134108.8809.974501109.71600-0.454203.608402.75430HepG2NSUN2
ARL8BENSG00000134108.81948.313301172.557900.732504.757103.57120HepG2PABPC1
ARL8BENSG00000134108.81132.573701346.89190-0.250002.574501.98340HepG2PCBP1
ARL8BENSG00000134108.81084.105201370.47230-0.338203.866603.24390HepG2PTBP1
ARL8BENSG00000134108.8925.285501484.34190-0.6819011.8143010.65670HepG2QKI
ARL8BENSG00000134108.82418.13400933.626801.3729014.5864013.08580HepG2RAVER1
ARL8BENSG00000134108.82290.697201483.461900.6267013.6560012.67960HepG2RBM22
ARL8BENSG00000134108.81127.473901525.23780-0.435906.482405.71350HepG2NELFE
ARL8BENSG00000134108.81092.446701420.49050-0.378805.128104.32310HepG2RECQL
ARL8BENSG00000134108.8857.160901288.07590-0.587604.167803.18580HepG2RPS3A
ARL8BENSG00000134108.8955.38230759.856700.330302.028301.34500HepG2RRP9
ARL8BENSG00000134108.8980.32400692.914800.500504.237803.08180HepG2SERBP1
ARL8BENSG00000134108.82369.892301140.585301.0549013.2342011.69340HepG2SF3A3
ARL8BENSG00000134108.81796.292901238.858200.535906.036505.02780HepG2SF3B1
ARL8BENSG00000134108.81052.605601281.78850-0.284203.589702.80710HepG2SLBP
ARL8BENSG00000134108.81257.818401062.887100.242802.705902.06690HepG2SMN1
ARL8BENSG00000134108.82915.674601675.539400.7991030.1811028.98650HepG2SRFBP1
ARL8BENSG00000134108.82136.490901489.356800.520507.948707.24370HepG2SRSF1
ARL8BENSG00000134108.82073.983501332.902200.637704.940603.56890HepG2SRSF3
ARL8BENSG00000134108.81725.844801454.806400.246401.903301.45730HepG2SSB
ARL8BENSG00000134108.81123.140801501.19690-0.418607.381606.44590HepG2SUCLG1
ARL8BENSG00000134108.81249.09170991.000800.333802.260501.64050HepG2SUPV3L1
ARL8BENSG00000134108.81044.211001338.60950-0.358304.128503.46490HepG2TAF15
ARL8BENSG00000134108.8734.947301003.39410-0.449206.053005.27600HepG2TRIM56
ARL8BENSG00000134108.8798.77600585.460600.448103.423702.58390HepG2UCHL5
ARL8BENSG00000134108.81519.76620976.588100.6379013.6906012.51020HepG2UTP3
ARL8BENSG00000134108.8734.14340975.52950-0.410102.263901.60250HepG2XRN2
ARL8BENSG00000134108.81330.22380934.706300.509009.404908.28910HepG2ZC3H8
ARL8BENSG00000134108.81564.392001112.484000.4917010.514309.62040HepG2ZNF622
ARL8BENSG00000134108.85713.132503899.797300.5508017.6084016.29890K562AGGF1
ARL8BENSG00000134108.84968.527804057.909900.292002.759102.10680K562AKAP8L
ARL8BENSG00000134108.85609.334104258.661100.397304.155903.46510K562AQR
ARL8BENSG00000134108.84406.909102900.492300.603408.229806.68830K562BOP1
ARL8BENSG00000134108.8955.866001191.64320-0.318102.346101.39290K562CCAR1
ARL8BENSG00000134108.84413.353003084.078700.516905.435704.34430K562CPSF6
ARL8BENSG00000134108.81276.582302105.50100-0.721908.559905.82780K562DDX51
ARL8BENSG00000134108.82727.890801949.692100.484405.464304.15420K562EFTUD2
ARL8BENSG00000134108.82341.851302878.48650-0.297703.939602.47270K562EIF2S1
ARL8BENSG00000134108.81925.374302465.56340-0.356802.492501.41650K562EIF4B
ARL8BENSG00000134108.83911.862505309.97510-0.440808.937207.28590K562EIF4G2
ARL8BENSG00000134108.82002.492003410.35330-0.7681013.5266011.49630K562FIP1L1
ARL8BENSG00000134108.84414.734303137.932100.492403.759402.75830K562FMR1
ARL8BENSG00000134108.84508.532202919.635000.626802.336901.69500K562G3BP2
ARL8BENSG00000134108.83923.209702944.554700.413904.895903.84240K562GPKOW
ARL8BENSG00000134108.82222.112302954.95100-0.411206.509505.12840K562HNRNPU
ARL8BENSG00000134108.81735.348203210.76940-0.887709.419707.11800K562IGF2BP2
ARL8BENSG00000134108.86049.051504306.477300.490104.254903.20000K562KIF1C
ARL8BENSG00000134108.85278.163404122.341700.356503.701102.39320K562MAK16
ARL8BENSG00000134108.82547.761903369.64570-0.403402.543101.66210K562MATR3
ARL8BENSG00000134108.85979.924503381.510700.822408.806406.88450K562NAA15
ARL8BENSG00000134108.83597.332402807.975400.357302.771301.93970K562PCBP3
ARL8BENSG00000134108.82862.092502153.778300.410102.907102.08500K562POLR2G
ARL8BENSG00000134108.83089.262403871.38110-0.325602.962902.10990K562PPIG
ARL8BENSG00000134108.83392.983301897.270300.8385014.8258013.07490K562PRPF8
ARL8BENSG00000134108.81670.668802072.13620-0.310702.581101.71360K562PSIP1
ARL8BENSG00000134108.82441.973503280.07030-0.425702.710402.05240K562PTBP1
ARL8BENSG00000134108.87443.029105793.613200.361303.723002.77950K562PUF60
ARL8BENSG00000134108.87663.237606162.207200.314404.254902.90850K562PUM1
ARL8BENSG00000134108.86052.701004024.375600.588708.082207.20110K562PUS1
ARL8BENSG00000134108.85524.833003921.112600.4946010.399009.27350K562RBM15
ARL8BENSG00000134108.82289.294903159.22410-0.464704.647603.30560K562RPS3
ARL8BENSG00000134108.84191.139703121.727100.424906.246305.05860K562SF3A3
ARL8BENSG00000134108.84105.453602800.308600.551905.753104.31660K562SF3B1
ARL8BENSG00000134108.83636.878103035.482400.260702.685501.84420K562SF3B4
ARL8BENSG00000134108.81329.454501791.89880-0.430704.159202.82550K562SRFBP1
ARL8BENSG00000134108.82364.001203050.01630-0.367604.184402.84830K562SRSF4
ARL8BENSG00000134108.82666.144402160.343500.303403.318302.41820K562SYNCRIP
ARL8BENSG00000134108.82352.901303254.59310-0.468003.059502.31500K562TARDBP
ARL8BENSG00000134108.82431.983803139.30660-0.368302.318501.57650K562TIA1
ARL8BENSG00000134108.81510.275702117.00850-0.487205.505504.06110K562TRIM56
ARL8BENSG00000134108.82549.209601944.335300.390703.574902.40530K562UCHL5
ARL8BENSG00000134108.84319.657003354.570300.364707.975206.83200K562UPF1
ARL8BENSG00000134108.85930.658804080.254600.539402.637001.38270K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ARL8B is not available on ENCORE database.





2 RBPs can affect the splicing of ARL8B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEARL8BENSG00000134108.8chr3+521418552144255213834521390852157015215769-0.070000.000000.00011excludedK562AQR
A5SSARL8BENSG00000134108.8chr3+521218752122685212187521225152138345213908-0.079000.000000.00000shorterK562AQR
MXEARL8BENSG00000134108.8chr3+521570152157695216028521609952138345213908522034852213310.068000.000180.002001includedK562AQR
MXEARL8BENSG00000134108.8chr3+521381152139085214342521442552122365212268521570152157690.074000.000000.000001includedK562AQR
MXEARL8BENSG00000134108.8chr3+521383452139085214289521442552121875212241521570152157690.060000.000000.000001includedK562AQR
MXEARL8BENSG00000134108.8chr3+52157015215769521602852160995214331521442552203485221331-0.103000.002870.022582includedK562AQR
MXEARL8BENSG00000134108.8chr3+52143315214425521570152157695213834521390852160285216099-0.111000.001570.033182includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ARL8B is not avaliable on ENCORE database.