APPBP2

General Information

Gene Name       : APPBP2
Gene ID             : ENSG00000062725.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: APPBP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878APPBP2ENSG00000062725.98.917.748.32ENCSR000AEF
HepG2APPBP2ENSG00000062725.913.8118.4416.12ENCSR985KAT
K562APPBP2ENSG00000062725.93.824.644.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for APPBP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • APPBP2 RNA is bound by 9 proteins.  







eCLIP assay for APPBP2 is not avaliable on ENCORE database.





9 proteins are bound to APPBP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr175854137858541473-3'-UTR,CDS,intron-Distal,intron-Proximal3.745807.42278HepG2BCLAF1
chr175852506058525122-3'-UTR,CDS,intron-Distal,intron-Proximal3.791074.09885HepG2BCLAF1
chr175852928958529380-3'-UTR,CDS,intron-Distal5.471029.32793HepG2BCLAF1
chr175854371558543834-3'-UTR,CDS,intron-Distal,intron-Proximal3.965796.81385HepG2BCLAF1
chr175854363758543715-3'-UTR,CDS,intron-Distal,intron-Proximal3.752665.15500HepG2BCLAF1
chr175857185458571928-3'-UTR,5'-UTR,CDS,intron-Distal3.234403.94979HepG2BCLAF1
chr175855658058556635-3'-UTR,CDS,intron-Distal,intron-Proximal3.596054.57751HepG2U2AF2
chr175852319858523319-3'-UTR,intron-Distal3.366604.79181K562FAM120A
chr175860337258603502-5'-UTR,intron-Distal,intron-Proximal3.707593.63681K562RBM15
chr175860341658603509-5'-UTR,intron-Distal,intron-Proximal3.583534.93175HepG2GRWD1
chr175857779458577851-CDS,intron-Distal,intron-Proximal3.499143.95921HepG2U2AF2
chr175860311158603161-CDS,intron-Distal,intron-Proximal4.099078.78144HepG2PRPF8
chr175857168658571760-intron-Distal,intron-Proximal3.040374.43994HepG2U2AF2
chr175859668558596775-intron-Distal3.856633.38675HepG2ILF3
chr175859833658598503-intron-Distal4.371765.28518HepG2TAF15
chr175858171758581772-intron-Distal3.778043.45805K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for APPBP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for APPBP2 is not available on ENCORE database.

  • 83 RBPs can affect the levels of APPBP2.  








The Knockdown/knockout RNA-Seq assay for APPBP2 is not available on ENCORE database.





83 RBPs can affect the gene expression of APPBP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
APPBP2ENSG00000062725.51564.396102640.42210-0.755208.465507.59060HepG2AKAP1
APPBP2ENSG00000062725.52484.924501943.865600.354202.776202.09010HepG2AUH
APPBP2ENSG00000062725.5957.786801304.65040-0.445902.255901.41370HepG2BCCIP
APPBP2ENSG00000062725.51495.329301133.786200.399203.443402.44420HepG2BCLAF1
APPBP2ENSG00000062725.51810.990401438.195600.332402.790502.18990HepG2BOP1
APPBP2ENSG00000062725.51948.079801647.548400.241602.106001.42630HepG2CALR
APPBP2ENSG00000062725.51153.100801417.22820-0.297602.379401.75460HepG2CKAP4
APPBP2ENSG00000062725.51441.020001806.24960-0.325904.262903.49650HepG2CELF1
APPBP2ENSG00000062725.51599.483201339.637400.255702.408901.33030HepG2DDX1
APPBP2ENSG00000062725.51775.051701309.596100.438604.395103.55970HepG2DDX21
APPBP2ENSG00000062725.53202.810502529.326400.340502.569701.96500HepG2DDX3X
APPBP2ENSG00000062725.51666.078602172.73950-0.383102.592001.99350HepG2DDX6
APPBP2ENSG00000062725.51137.314701301.97820-0.195101.957201.39100HepG2DNAJC2
APPBP2ENSG00000062725.51717.987502088.71140-0.281901.799001.30890HepG2EIF2S1
APPBP2ENSG00000062725.51672.630402328.94520-0.477604.449703.58660HepG2FXR1
APPBP2ENSG00000062725.51721.258302160.44140-0.327902.142101.55410HepG2G3BP1
APPBP2ENSG00000062725.51880.897701496.786200.329502.155601.58700HepG2GPKOW
APPBP2ENSG00000062725.51016.044302187.63520-1.1064022.1332020.33950HepG2HNRNPK
APPBP2ENSG00000062725.51430.683401769.60050-0.306703.110002.39850HepG2HNRNPL
APPBP2ENSG00000062725.51543.164502196.04260-0.509005.047304.16000HepG2IGF2BP2
APPBP2ENSG00000062725.5999.266901496.82880-0.5830014.1857012.66840HepG2ILF2
APPBP2ENSG00000062725.51788.892702329.75830-0.381102.926402.25250HepG2MAGOH
APPBP2ENSG00000062725.51703.619202342.79860-0.459603.656002.93980HepG2MATR3
APPBP2ENSG00000062725.52002.831401456.671100.459302.603901.66710HepG2MTPAP
APPBP2ENSG00000062725.5960.320301450.47310-0.5949011.220109.70770HepG2PARN
APPBP2ENSG00000062725.51473.495902014.88730-0.451508.449207.48350HepG2PCBP1
APPBP2ENSG00000062725.51037.517301306.99470-0.333103.536202.71310HepG2PPIL4
APPBP2ENSG00000062725.5859.774801123.19810-0.385604.708603.72850HepG2PRPF4
APPBP2ENSG00000062725.51587.392302050.18040-0.369105.789005.05630HepG2PTBP1
APPBP2ENSG00000062725.51569.689601951.64810-0.314204.308903.60360HepG2PUM1
APPBP2ENSG00000062725.52325.895801865.325800.318304.144303.54320HepG2RBM22
APPBP2ENSG00000062725.51982.043602281.68950-0.203102.244401.74720HepG2NELFE
APPBP2ENSG00000062725.5949.710101304.98080-0.458507.526506.54030HepG2SAFB2
APPBP2ENSG00000062725.5561.925701013.80290-0.851306.093504.71620HepG2SERBP1
APPBP2ENSG00000062725.51051.167801413.87050-0.427703.730802.92360HepG2SF3B1
APPBP2ENSG00000062725.51219.024701521.83350-0.320105.027604.20350HepG2SMN1
APPBP2ENSG00000062725.52368.136601573.167700.590003.979403.03390HepG2SNRNP70
APPBP2ENSG00000062725.52756.173902106.852600.387508.469507.72380HepG2SRFBP1
APPBP2ENSG00000062725.52831.071002228.007200.345506.018405.38740HepG2SRSF1
APPBP2ENSG00000062725.51393.028001812.57560-0.379806.333905.55910HepG2SRSF9
APPBP2ENSG00000062725.52501.783901829.309400.451609.889409.03490HepG2SSB
APPBP2ENSG00000062725.51029.634401423.90210-0.467705.815205.14090HepG2TIAL1
APPBP2ENSG00000062725.51115.342701436.60870-0.365205.020804.30630HepG2TRIM56
APPBP2ENSG00000062725.51395.855901730.20550-0.309803.833002.61820HepG2UTP18
APPBP2ENSG00000062725.51358.449301625.15420-0.258602.996502.37810HepG2UTP3
APPBP2ENSG00000062725.51476.095901108.441600.413207.010606.02150HepG2ZC3H8
APPBP2ENSG00000062725.51530.927801851.30030-0.274104.218303.58170HepG2ZNF622
APPBP2ENSG00000062725.5220.98670546.77630-1.3070016.0688014.81640K562AGGF1
APPBP2ENSG00000062725.5195.82780292.25380-0.577603.861302.04680K562AKAP1
APPBP2ENSG00000062725.5199.97260568.92930-1.5084016.1561014.34010K562AKAP8L
APPBP2ENSG00000062725.51478.03070690.160501.0986018.7546017.39610K562AQR
APPBP2ENSG00000062725.5458.75640596.91290-0.379802.180701.37730K562ATP5C1
APPBP2ENSG00000062725.5710.71040441.488700.686805.967104.67570K562BOP1
APPBP2ENSG00000062725.51141.48080678.002600.7514014.7035013.31710K562DDX47
APPBP2ENSG00000062725.5482.67060612.31090-0.343202.364201.56330K562DKC1
APPBP2ENSG00000062725.5607.94290475.665300.353902.649901.94320K562EIF2S2
APPBP2ENSG00000062725.51004.86810789.592900.347703.686702.60260K562EIF4G2
APPBP2ENSG00000062725.5379.16330540.20250-0.510703.558702.58690K562FIP1L1
APPBP2ENSG00000062725.5391.60950283.200700.467502.388401.35220K562FKBP4
APPBP2ENSG00000062725.5661.27150477.654400.469203.169702.24920K562FMR1
APPBP2ENSG00000062725.5649.64080404.874800.682105.464704.13120K562FTO
APPBP2ENSG00000062725.5586.59420321.715500.8665011.021809.89960K562FXR1
APPBP2ENSG00000062725.5279.70000467.37480-0.740706.461604.16390K562G3BP1
APPBP2ENSG00000062725.5249.59850479.82800-0.942904.461502.80150K562HNRNPA2B1
APPBP2ENSG00000062725.5580.88410326.533700.830907.745206.79310K562HNRNPC
APPBP2ENSG00000062725.5310.37950488.30770-0.653804.415402.82250K562HNRNPK
APPBP2ENSG00000062725.51017.36620732.393100.474003.965403.01650K562HSPD1
APPBP2ENSG00000062725.5288.61330488.68950-0.759805.167403.58640K562IGF2BP2
APPBP2ENSG00000062725.5406.13640603.83330-0.572205.171503.97320K562KIF1C
APPBP2ENSG00000062725.5400.53010513.77700-0.359202.149001.40420K562MAGOH
APPBP2ENSG00000062725.5527.92160676.43790-0.357602.457901.60910K562MBNL1
APPBP2ENSG00000062725.5319.94440474.12890-0.567502.934102.02170K562NAA15
APPBP2ENSG00000062725.5218.75660321.37680-0.554902.872601.41270K562NUSAP1
APPBP2ENSG00000062725.5245.73880419.70370-0.772203.028501.98300K562PABPN1
APPBP2ENSG00000062725.5334.70840502.12890-0.585204.882403.03930K562PCBP1
APPBP2ENSG00000062725.5695.75890400.625400.796206.948205.62750K562PCBP3
APPBP2ENSG00000062725.5539.89860307.266000.813104.875703.80960K562POLR2G
APPBP2ENSG00000062725.5301.96530498.97140-0.724602.752101.32670K562PPP1R8
APPBP2ENSG00000062725.5208.40700292.74870-0.490302.228501.42470K562PSIP1
APPBP2ENSG00000062725.5323.38100499.15280-0.626205.554504.64150K562PTBP1
APPBP2ENSG00000062725.51952.03600861.516601.1799025.0449022.52960K562PUF60
APPBP2ENSG00000062725.51213.33920916.278900.405004.171502.84330K562PUM1
APPBP2ENSG00000062725.51143.64120897.852700.349003.674302.56710K562PUM2
APPBP2ENSG00000062725.5198.58090564.33840-1.5068017.7787016.43980K562PUS1
APPBP2ENSG00000062725.5288.68900549.76610-0.9293011.4158010.22940K562RBM15
APPBP2ENSG00000062725.5263.58910516.34820-0.970104.190802.19220K562RBM39
APPBP2ENSG00000062725.5677.41410503.761400.427202.867901.75310K562NELFE
APPBP2ENSG00000062725.5596.37890355.431200.746605.887804.69130K562RPS19
APPBP2ENSG00000062725.5365.80350221.971000.720603.942302.71900K562RPS3
APPBP2ENSG00000062725.5121.36530298.59400-1.298804.665002.62210K562SERBP1
APPBP2ENSG00000062725.5697.96580489.315600.512304.517303.61780K562SRSF1
APPBP2ENSG00000062725.5346.41640462.07070-0.415602.375501.41390K562SRSF5
APPBP2ENSG00000062725.5286.16100441.16520-0.624505.229903.37700K562SSB
APPBP2ENSG00000062725.5406.70330308.233500.399902.247701.50640K562SYNCRIP
APPBP2ENSG00000062725.5377.19770495.26370-0.392902.155601.52640K562TARDBP
APPBP2ENSG00000062725.5311.71590468.68630-0.588403.969902.62650K562TRA2A
APPBP2ENSG00000062725.5213.74310299.02810-0.484402.155801.33680K562TRIM56
APPBP2ENSG00000062725.5722.87030491.053400.557806.601705.54600K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for APPBP2 is not available on ENCORE database.





1 RBPs can affect the splicing of APPBP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAPPBP2ENSG00000062725.5chr17-585336565853374258531662585318535853802358538148-0.175000.000010.00017excludedK562AQR
A3SSAPPBP2ENSG00000062725.5chr17-5854138158541618585413815854147158543651585438440.055000.003260.01983longerK562AQR
A3SSAPPBP2ENSG00000062725.5chr17-5854365158543844585436515854382058556508585566640.116000.000360.00275longerK562AQR
A3SSAPPBP2ENSG00000062725.5chr17-5853365658533773585336565853374258538023585381480.091000.003050.01872longerK562AQR
MXEAPPBP2ENSG00000062725.5chr17-5853802358538148585393545853942258531662585318535854138158541471-0.146000.000220.002402includedK562AQR
MXEAPPBP2ENSG00000062725.5chr17-5853802358538148585391705853927658531662585318535853935458539422-0.265000.000030.000372includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for APPBP2 is not avaliable on ENCORE database.