WWP2

General Information

Gene Name       : WWP2
Gene ID             : ENSG00000198373.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: WWP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WWP2ENSG00000198373.1221.2818.6819.98ENCSR000AEF
HepG2WWP2ENSG00000198373.1227.7322.3525.04ENCSR985KAT
K562WWP2ENSG00000198373.1216.6918.2517.47ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WWP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WWP2 RNA is bound by 25 proteins.  







eCLIP assay for WWP2 is not avaliable on ENCORE database.





25 proteins are bound to WWP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr166997374969973855+3'-UTR,CDS4.404304.01763HepG2GRWD1
chr166997547869975562+3'-UTR5.825985.71015K562PABPC4
chr166997466469974735+3'-UTR5.128767.45692HepG2UPF1
chr166987402669874108+3'-UTR,5'-UTR,CDS,intron-Proximal4.0573011.55292HepG2PPIG
chr166997385069974000+3'-UTR6.6459723.16107HepG2UPF1
chr166997432069974414+3'-UTR5.5355512.58146HepG2UPF1
chr166997480769974882+3'-UTR5.1538216.83940HepG2UPF1
chr166997407269974125+3'-UTR4.759846.75461HepG2AKAP1
chr166997518569975247+3'-UTR3.749263.72765HepG2UPF1
chr166997488869974966+3'-UTR5.6096910.81337K562UPF1
chr166997524769975310+3'-UTR3.378725.69025HepG2UPF1
chr166997429969974401+3'-UTR5.178818.89452HepG2AKAP1
chr166997395769974022+3'-UTR4.692144.92727HepG2AKAP1
chr166994271869942793+3'-UTR,CDS,intron-Proximal4.2493312.28861HepG2PRPF8
chr166987402769874171+3'-UTR,5'-UTR,CDS,intron-Proximal3.650848.66838HepG2BCLAF1
chr166997536169975438+3'-UTR4.683843.61011HepG2AKAP1
chr166997549369975585+3'-UTR5.7355112.02344K562UPF1
chr166997414869974221+3'-UTR4.768805.97422HepG2AKAP1
chr166997529269975319+3'-UTR3.634144.50550K562UPF1
chr166997397569974181+3'-UTR4.5748220.03105K562UPF1
chr166997481069974878+3'-UTR5.126528.61963HepG2AKAP1
chr166997538169975478+3'-UTR4.714786.24350K562PABPC4
chr166997480669974872+3'-UTR4.577569.20161K562UPF1
chr166997431569974395+3'-UTR5.511689.60749K562UPF1
chr166997452869974638+3'-UTR4.9474119.05397K562UPF1
chr166997525569975330+3'-UTR4.913555.97422HepG2AKAP1
chr166997456169974607+3'-UTR4.646755.41597HepG2UPF1
chr166997488669974943+3'-UTR5.2305310.25977HepG2UPF1
chr166997455169974618+3'-UTR3.883805.63973HepG2AKAP1
chr166997415369974247+3'-UTR5.4582311.24187HepG2UPF1
chr166997388969973957+3'-UTR4.241587.20393HepG2AKAP1
chr166995933769959390+5'-UTR,CDS,intron-Proximal3.286103.47879HepG2PPIG
chr166987411769874175+CDS,intron-Proximal4.808003.25266K562DDX24
chr166996570469965795+CDS,intron-Proximal4.244186.08299HepG2PPIG
chr166997026969970346+CDS4.156343.39686HepG2G3BP1
chr166996571869965797+CDS,intron-Proximal4.955284.94356HepG2PRPF8
chr166996547869965574+CDS,intron-Proximal3.7778513.02279HepG2PRPF8
chr166996979069969878+CDS4.325095.11007HepG2GRWD1
chr166987593069875986+CDS3.105633.60157HepG2GRWD1
chr166987592669876029+CDS,intron-Proximal3.5261011.82429HepG2PPIG
chr166996547169965528+CDS,intron-Proximal4.943476.38747HepG2AQR
chr166983311669833204+CDS,intron-Proximal3.390928.10600HepG2PPIG
chr166983259069832681+CDS4.281584.48692K562YBX3
chr166987594669876011+CDS3.780963.11282HepG2G3BP1
chr166996802669968039+CDS,intron-Proximal3.940996.23016HepG2PRPF8
chr166996563669965752+CDS,intron-Proximal4.293696.78984HepG2AQR
chr166987410869874167+CDS,intron-Proximal3.347416.00907HepG2PPIG
chr166995178369951825+CDS,intron-Proximal4.229053.93614HepG2AQR
chr166990570669905749+CDS,intron-Proximal3.627124.68902HepG2PPIG
chr166983310069833200+CDS,intron-Proximal4.230925.94293HepG2BCLAF1
chr166996653269966588+intron-Distal3.114683.75965HepG2DROSHA
chr166985842869858498+intron-Distal5.0647819.52418HepG2PCBP2
chr166979635569796467+intron-Distal,intron-Proximal4.068354.61345HepG2FAM120A
chr166996739269967475+intron-Distal3.968596.68663HepG2DROSHA
chr166985059069850730+intron-Distal4.276619.36782K562HNRNPL
chr166996692969966998+intron-Distal5.3511810.87655HepG2DGCR8
chr166985059069850652+intron-Distal4.048229.51524HepG2HNRNPL
chr166983359769833681+intron-Distal5.1911910.25043K562TARDBP
chr166996699869967069+intron-Distal7.3373339.38420HepG2DGCR8
chr166990252369902588+intron-Distal3.941703.02891HepG2HNRNPL
chr166994855269948612+intron-Distal4.665505.31233HepG2HLTF
chr166994533969945447+intron-Distal4.700305.52571HepG2RBFOX2
chr166996727869967355+intron-Distal5.2956811.15844HepG2DGCR8
chr166979636469796448+intron-Distal,intron-Proximal4.141773.15816HepG2PRPF4
chr166979635669796471+intron-Distal,intron-Proximal3.189733.04847HepG2CSTF2T
chr166996691169966993+intron-Distal3.936526.23256HepG2DROSHA
chr166996634369966387+intron-Distal3.470174.68205HepG2DGCR8
chr166979651469796560+intron-Distal4.156364.83107HepG2EFTUD2
chr166996727569967391+intron-Distal4.0811611.01821HepG2DROSHA
chr166996727569967372+intron-Distal5.652426.75658K562DROSHA
chr166985065269850725+intron-Distal4.3787312.24567HepG2HNRNPL
chr166996739569967417+intron-Distal4.259324.69797HepG2DGCR8
chr166987386469873930+intron-Distal,intron-Proximal4.540373.35169HepG2U2AF2
chr166979637369796504+intron-Distal,intron-Proximal4.8887015.65149HepG2EFTUD2
chr166996651869966555+intron-Distal4.285564.92660HepG2DGCR8
chr166985073669850780+intron-Distal4.498784.24565HepG2HNRNPL
chr166985068669850767+intron-Distal5.256487.88608K562AGGF1
chr166996702669967069+intron-Distal6.8021218.66157K562DGCR8
chr166979633369796464+intron-Distal,intron-Proximal4.717076.62122HepG2RBFOX2
chr166979637769796464+intron-Distal,intron-Proximal4.214184.13073HepG2GTF2F1
chr166997036269970436+intron-Proximal4.850156.92731HepG2PRPF8
chr166996803969968077+intron-Proximal3.437785.73990HepG2PRPF8
chr166996565569965691+intron-Proximal3.183713.23382HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WWP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WWP2 is not available on ENCORE database.

  • 79 RBPs can affect the levels of WWP2.  








The Knockdown/knockout RNA-Seq assay for WWP2 is not available on ENCORE database.





79 RBPs can affect the gene expression of WWP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WWP2ENSG00000198373.8624.86030944.15950-0.595505.932904.42200HepG2AATF
WWP2ENSG00000198373.8894.038401248.71310-0.482003.025301.93810HepG2AKAP8
WWP2ENSG00000198373.81770.992402050.11980-0.211202.234801.60550HepG2AUH
WWP2ENSG00000198373.82169.308801591.808600.446504.724303.96840HepG2BOP1
WWP2ENSG00000198373.8951.256701183.32870-0.314902.183001.49250HepG2CALR
WWP2ENSG00000198373.82020.773001297.360200.639207.421406.20220HepG2CIRBP
WWP2ENSG00000198373.81067.82350607.266500.814205.732504.63120HepG2CNOT7
WWP2ENSG00000198373.81141.746101461.35730-0.356102.663401.98690HepG2CPSF6
WWP2ENSG00000198373.8641.64910966.88800-0.591603.934302.21300HepG2CSTF2T
WWP2ENSG00000198373.81113.805801392.99070-0.322703.446702.74660HepG2CELF1
WWP2ENSG00000198373.81720.068101497.718000.199602.305001.62010HepG2DAZAP1
WWP2ENSG00000198373.81221.90910875.080200.481506.150604.49410HepG2DDX1
WWP2ENSG00000198373.8737.158101580.79040-1.100609.938508.81910HepG2DDX3X
WWP2ENSG00000198373.8637.454401358.44400-1.091609.694208.61360HepG2DDX6
WWP2ENSG00000198373.81069.17360850.430000.330103.993503.23880HepG2DNAJC2
WWP2ENSG00000198373.81433.09350997.196200.523104.629203.46140HepG2EEF2
WWP2ENSG00000198373.8578.90220959.15500-0.728405.988004.36790HepG2AGO1
WWP2ENSG00000198373.81072.194801442.37080-0.427902.864802.21510HepG2EIF4A3
WWP2ENSG00000198373.81011.276101404.81990-0.474202.853702.15560HepG2EIF4B
WWP2ENSG00000198373.81229.252701477.66750-0.265502.529301.72130HepG2EIF4G1
WWP2ENSG00000198373.81345.811902353.84610-0.8065024.9186023.42430HepG2ETF1
WWP2ENSG00000198373.81080.034501384.62760-0.358403.255202.34890HepG2EWSR1
WWP2ENSG00000198373.8736.53670956.73340-0.377402.578701.34870HepG2FKBP4
WWP2ENSG00000198373.8804.738701463.88240-0.863204.024702.79760HepG2FTO
WWP2ENSG00000198373.81786.802201434.023200.317202.142701.36500HepG2G3BP2
WWP2ENSG00000198373.8957.36160720.637000.409702.733401.84100HepG2GEMIN5
WWP2ENSG00000198373.8778.78340562.174900.470102.372701.34050HepG2GRSF1
WWP2ENSG00000198373.8975.993101368.21050-0.487302.535301.86480HepG2HNRNPK
WWP2ENSG00000198373.81152.02240957.206800.267202.721002.11940HepG2HNRNPU
WWP2ENSG00000198373.81908.744701539.647900.309902.953002.20710HepG2IGF2BP1
WWP2ENSG00000198373.82083.865201372.406400.602506.565305.56590HepG2IGF2BP2
WWP2ENSG00000198373.81166.81610977.759300.254902.989502.22980HepG2ILF2
WWP2ENSG00000198373.81856.041501456.547700.349602.124501.54700HepG2MAGOH
WWP2ENSG00000198373.81741.008601485.138800.229202.046501.38820HepG2NOL12
WWP2ENSG00000198373.81044.294001401.75840-0.424703.595502.74270HepG2NSUN2
WWP2ENSG00000198373.81680.438401334.486600.332502.167401.52340HepG2PABPC4
WWP2ENSG00000198373.81026.36880853.756300.265602.185501.52300HepG2PPIL4
WWP2ENSG00000198373.8837.925701504.68580-0.8446021.2549019.46270HepG2PRPF4
WWP2ENSG00000198373.81876.575801505.000800.318205.559304.77970HepG2PUM1
WWP2ENSG00000198373.82038.880901564.536500.381904.956504.15650HepG2QKI
WWP2ENSG00000198373.81484.960401790.20420-0.269702.446801.63520HepG2RBM15
WWP2ENSG00000198373.81525.88350884.466900.786707.900606.13130HepG2RCC2
WWP2ENSG00000198373.81235.511701497.55160-0.277502.886202.25820HepG2RECQL
WWP2ENSG00000198373.81564.691401025.765900.609102.769201.82510HepG2RPS10
WWP2ENSG00000198373.81056.69260787.683700.423803.650702.95410HepG2RPS19
WWP2ENSG00000198373.81010.92630609.905300.728905.672004.52480HepG2RPS3A
WWP2ENSG00000198373.81010.69980852.449600.245602.275201.68190HepG2SAFB2
WWP2ENSG00000198373.81086.86590790.403300.459403.473102.41630HepG2SERBP1
WWP2ENSG00000198373.81629.140901359.431300.261003.570502.79030HepG2SLBP
WWP2ENSG00000198373.81330.10710994.124900.419904.500803.71550HepG2SMN1
WWP2ENSG00000198373.8892.353101741.04030-0.964308.789007.40540HepG2SNRNP70
WWP2ENSG00000198373.8978.024801399.82620-0.517308.394507.38000HepG2SRSF5
WWP2ENSG00000198373.8686.722701277.27160-0.8953022.5363021.24070HepG2SRSF9
WWP2ENSG00000198373.8942.102301371.13470-0.541403.880302.29210HepG2SUGP2
WWP2ENSG00000198373.8578.356901144.23810-0.9844012.2987011.04080HepG2SUPV3L1
WWP2ENSG00000198373.8665.698301411.26450-1.0840027.0995025.58100HepG2TAF15
WWP2ENSG00000198373.81026.455201296.60640-0.337102.988502.12300HepG2TIA1
WWP2ENSG00000198373.81123.16940930.198100.271902.110301.66200HepG2TIAL1
WWP2ENSG00000198373.82351.049601469.267000.678108.824707.69730HepG2U2AF1
WWP2ENSG00000198373.81961.752701466.136600.420003.299602.38690HepG2UBE2L3
WWP2ENSG00000198373.81276.263801638.78020-0.360705.473304.54280HepG2UPF1
WWP2ENSG00000198373.8790.03990546.300300.532103.149201.97120HepG2XPO5
WWP2ENSG00000198373.82650.886701802.346600.5565017.8163016.72830HepG2ZNF622
WWP2ENSG00000198373.81395.166401045.397100.416303.496802.85270K562AQR
WWP2ENSG00000198373.8933.89240696.358700.423302.994202.08500K562BOP1
WWP2ENSG00000198373.81017.18770740.395900.458104.370203.38580K562CPSF6
WWP2ENSG00000198373.81184.44150965.608700.294602.810402.08630K562EIF2S2
WWP2ENSG00000198373.81190.11000943.156600.335402.808601.53510K562EXOSC5
WWP2ENSG00000198373.8920.72440680.367100.436404.009003.30030K562FXR1
WWP2ENSG00000198373.8280.06100383.83190-0.454701.986901.40040K562G3BP2
WWP2ENSG00000198373.8897.92630706.869400.345102.388801.64840K562GPKOW
WWP2ENSG00000198373.8918.72630701.927300.388203.018902.39870K562HNRNPC
WWP2ENSG00000198373.8777.17840569.677600.448003.646602.23830K562IGF2BP3
WWP2ENSG00000198373.8744.52160588.474000.339202.370401.58970K562MAGOH
WWP2ENSG00000198373.8675.27470523.549600.367002.353101.45610K562PCBP2
WWP2ENSG00000198373.8865.82610571.758400.598606.825405.81730K562PTBP1
WWP2ENSG00000198373.81531.186001133.315500.434004.147003.50180K562PUS1
WWP2ENSG00000198373.8753.79660548.108800.459602.740401.90440K562RBM22
WWP2ENSG00000198373.81349.242901132.965200.251902.254201.51230K562SF3A3
WWP2ENSG00000198373.8527.27340398.901300.402402.753501.90110K562SF3B4
WWP2ENSG00000198373.8877.69790560.542500.646807.329506.18800K562SRSF1
WWP2ENSG00000198373.8905.42810567.243900.674506.879905.71620K562TARDBP
WWP2ENSG00000198373.8760.37340547.187000.474604.159203.12450K562TIA1
WWP2ENSG00000198373.81471.678001217.480700.273502.307901.64780K562UPF1
WWP2ENSG00000198373.8925.269301083.29140-0.227502.122601.37400K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WWP2 is not available on ENCORE database.





5 RBPs can affect the splicing of WWP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSWWP2ENSG00000198373.8chr16+6987399869874166698740286987416669833076698331980.110000.000030.00025longerK562AQR
A3SSWWP2ENSG00000198373.8chr16+6983306169833198698330766983319869832584698327320.138000.000090.00082longerK562AQR
RIWWP2ENSG00000198373.8chr16+6996541169965793699654116996548369965704699657930.160000.000080.00403includedHepG2FTO
RIWWP2ENSG00000198373.8chr16+6996541169965793699654116996548369965704699657930.077000.001000.02030includedHepG2G3BP1
RIWWP2ENSG00000198373.8chr16+6996541169965793699654116996548369965704699657930.222000.000010.00029includedHepG2TIAL1
RIWWP2ENSG00000198373.8chr16+6996541169965793699654116996548369965704699657930.068000.003120.03411includedHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WWP2 is not avaliable on ENCORE database.