WFS1

General Information

Gene Name       : WFS1
Gene ID             : ENSG00000109501.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: WFS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WFS1ENSG00000109501.130.210.690.45ENCSR000AEF
HepG2WFS1ENSG00000109501.1355.4511.0233.23ENCSR985KAT
K562WFS1ENSG00000109501.130.090.020.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WFS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WFS1 RNA is bound by 16 proteins.  







eCLIP assay for WFS1 is not avaliable on ENCORE database.





16 proteins are bound to WFS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr463045606304618+3'-UTR3.557314.77155HepG2AKAP1
chr463046276304768+3'-UTR5.6786011.05965HepG2AKAP1
chr463044246304498+3'-UTR4.476325.58306HepG2AKAP1
chr463046376304769+3'-UTR5.8888016.62098HepG2UPF1
chr463048806304946+3'-UTR3.782974.91517HepG2LARP4
chr463045046304575+3'-UTR6.6288844.96757HepG2PCBP2
chr463042336304321+3'-UTR4.9925815.97458HepG2UPF1
chr463043326304390+3'-UTR3.142614.25624HepG2AKAP1
chr463043216304382+3'-UTR4.922456.96152HepG2UPF1
chr463048356304929+3'-UTR5.6502913.32795HepG2UPF1
chr463044236304472+3'-UTR4.456784.68979HepG2UPF1
chr462791816279247+5'-UTR,CDS,intron-Proximal3.2104811.53192HepG2DDX3X
chr462716706271718+5'-UTR3.7877512.11309HepG2RPS3
chr462907016290746+CDS,intron-Proximal3.695874.68902HepG2PPIG
chr462888396288922+CDS,intron-Proximal3.238325.47500HepG2PPIG
chr462793006279380+CDS3.4297511.45803HepG2RPS3
chr463036896303821+CDS4.7979424.16233HepG2SND1
chr462888886288948+CDS,intron-Proximal3.366917.19667HepG2PRPF8
chr463039706304044+CDS4.3686312.63735HepG2SND1
chr462936446293672+CDS3.589126.12687HepG2RPS3
chr462967776296845+CDS3.790146.91167HepG2GRWD1
chr463040576304130+CDS4.098577.59025HepG2SND1
chr462929386293095+CDS,intron-Proximal4.3773926.95825HepG2RPS3
chr462794036279460+CDS,intron-Proximal4.207367.79098HepG2PRPF8
chr463032296303295+CDS4.1429813.20660HepG2SND1
chr463032286303289+CDS3.5969412.03336HepG2RPS3
chr463034006303463+CDS3.583709.41084HepG2SND1
chr462936996293773+CDS,intron-Proximal3.9955223.52891HepG2PRPF8
chr463038546303912+CDS3.462137.75513HepG2SND1
chr463027656302815+CDS3.413878.45760HepG2RPS3
chr463034816303511+CDS3.745267.21038HepG2SND1
chr462968756296917+CDS,intron-Proximal3.995383.39686HepG2G3BP1
chr462888536288901+CDS4.9743814.17180HepG2RPS3
chr463028586302890+CDS5.207667.33420HepG2SND1
chr462967056296902+CDS,intron-Proximal3.243336.63612HepG2AQR
chr463035166303565+CDS3.652458.24547HepG2SND1
chr463033206303341+CDS4.045124.67599HepG2SND1
chr462907686290809+CDS4.145239.04754HepG2RPS3
chr462906876290761+CDS,intron-Proximal4.304703.25089HepG2AQR
chr462967496296806+CDS,intron-Proximal4.303688.77485HepG2PRPF8
chr462906466290716+CDS,intron-Proximal4.220806.88258HepG2RBFOX2
chr462959146295969+intron-Distal3.560243.48223HepG2RBFOX2
chr463016706301754+intron-Distal5.179189.99173HepG2CSTF2T
chr463006026300655+intron-Distal4.116313.63902HepG2CSTF2T
chr463017546301793+intron-Distal4.005113.63902HepG2CSTF2T
chr463016606301728+intron-Distal4.709186.46885HepG2FAM120A
chr462818596281915+intron-Distal3.163673.48399HepG2CSTF2T
chr462958736295995+intron-Distal3.392036.31016HepG2HNRNPK
chr462940586294147+intron-Distal3.515377.15495HepG2RBFOX2
chr463017506301806+intron-Distal3.533164.88931HepG2FAM120A
chr462964606296564+intron-Distal3.390219.32468HepG2RBFOX2
chr462960856296198+intron-Distal4.4268014.56640HepG2RBFOX2
chr462962396296332+intron-Distal4.282057.07105HepG2RBFOX2
chr463020336302103+intron-Distal4.408794.68055HepG2CSTF2T
chr463016616301730+intron-Distal4.170853.65854HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WFS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WFS1 is not available on ENCORE database.

  • 99 RBPs can affect the levels of WFS1.  








The Knockdown/knockout RNA-Seq assay for WFS1 is not available on ENCORE database.





99 RBPs can affect the gene expression of WFS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WFS1ENSG00000109501.91464.332802659.01200-0.860607.430205.98900HepG2ABCF1
WFS1ENSG00000109501.92493.478601638.567300.605605.895004.40770HepG2AKAP8
WFS1ENSG00000109501.92911.129801991.501800.547607.173805.26260HepG2BUD13
WFS1ENSG00000109501.9761.851601405.41200-0.883406.732705.59980HepG2CALR
WFS1ENSG00000109501.9307.23550828.14460-1.430503.635802.75360HepG2CNOT7
WFS1ENSG00000109501.91274.541901916.14710-0.588206.935905.88590HepG2CPSF6
WFS1ENSG00000109501.92904.630102188.884700.408104.268402.91100HepG2CPSF7
WFS1ENSG00000109501.91202.76180907.214100.406704.789903.45240HepG2YBX3
WFS1ENSG00000109501.9424.45040624.12110-0.556202.367901.36750HepG2CSTF2
WFS1ENSG00000109501.9438.09270851.81670-0.959302.916301.51110HepG2CSTF2T
WFS1ENSG00000109501.92242.301001205.223400.8956020.3131018.89680HepG2CELF1
WFS1ENSG00000109501.91299.39940908.432700.516303.068601.85490HepG2DDX1
WFS1ENSG00000109501.9559.73270916.04300-0.710703.824703.03950HepG2DDX21
WFS1ENSG00000109501.9471.84760897.46790-0.927505.070403.82680HepG2DDX24
WFS1ENSG00000109501.9545.61150929.78170-0.769003.290101.89300HepG2DDX27
WFS1ENSG00000109501.92565.441801072.432101.2582015.4754014.11540HepG2DDX3X
WFS1ENSG00000109501.91464.445001010.194200.535603.352501.85900HepG2DDX52
WFS1ENSG00000109501.92359.52850921.886601.3557010.039408.94300HepG2DDX6
WFS1ENSG00000109501.9791.254401766.00710-1.1583039.8113038.03020HepG2DKC1
WFS1ENSG00000109501.91187.92540890.749400.415303.107302.36640HepG2DNAJC21
WFS1ENSG00000109501.91206.70770882.980900.450503.010102.33500HepG2DNAJC2
WFS1ENSG00000109501.91690.68720885.591600.932804.513803.76660HepG2EIF2S1
WFS1ENSG00000109501.9538.00270865.75470-0.686303.626602.41050HepG2EIF3G
WFS1ENSG00000109501.9858.059301397.46380-0.703707.055604.00680HepG2EIF3H
WFS1ENSG00000109501.9712.504201278.48590-0.8435018.1510016.40100HepG2EIF4G1
WFS1ENSG00000109501.91241.400802302.82100-0.891407.829706.12260HepG2ESF1
WFS1ENSG00000109501.91512.482002866.80720-0.922509.622908.61070HepG2ETF1
WFS1ENSG00000109501.91451.624601803.79610-0.313402.830401.98570HepG2EWSR1
WFS1ENSG00000109501.91179.28970874.437900.431402.861601.67190HepG2FAM120A
WFS1ENSG00000109501.91030.507301919.48290-0.897404.399103.12680HepG2FTO
WFS1ENSG00000109501.91249.05920838.807200.574302.882002.08040HepG2FUBP3
WFS1ENSG00000109501.92716.18010988.074701.4588024.8881023.05650HepG2FXR1
WFS1ENSG00000109501.91490.01900916.091100.701703.559702.80870HepG2G3BP1
WFS1ENSG00000109501.91207.64010750.821100.685503.691702.51010HepG2GNB2L1
WFS1ENSG00000109501.92540.227301762.310200.5274010.724108.97790HepG2HDGF
WFS1ENSG00000109501.91267.33760701.414900.853404.752802.91530HepG2HNRNPA0
WFS1ENSG00000109501.9538.31690899.28410-0.740305.033804.19740HepG2HNRNPA1
WFS1ENSG00000109501.91251.27900684.822600.869505.223903.27020HepG2HNRNPAB
WFS1ENSG00000109501.91647.48290928.776400.826804.779203.88180HepG2HNRNPK
WFS1ENSG00000109501.92021.689101180.380100.7762027.4817025.61640HepG2HNRNPL
WFS1ENSG00000109501.91581.49620993.703700.670305.476204.64530HepG2HNRNPU
WFS1ENSG00000109501.91067.286701783.65060-0.740907.354405.39440HepG2HSPD1
WFS1ENSG00000109501.91648.02770931.011200.823804.167303.35360HepG2IGF2BP2
WFS1ENSG00000109501.91203.577801015.029900.245702.727101.99920HepG2ILF2
WFS1ENSG00000109501.91957.568801687.390800.214202.793901.77350HepG2KIF1C
WFS1ENSG00000109501.91318.45150735.948900.841106.069704.41200HepG2LARP7
WFS1ENSG00000109501.91721.35850993.803500.792403.550602.84390HepG2MATR3
WFS1ENSG00000109501.91495.896502114.15360-0.499102.821601.84460HepG2MTPAP
WFS1ENSG00000109501.92491.903601017.089201.2927016.2696014.81820HepG2NCBP2
WFS1ENSG00000109501.92054.659701284.948800.677107.747606.48840HepG2NOL12
WFS1ENSG00000109501.91056.22760709.701100.573502.951401.45250HepG2NOLC1
WFS1ENSG00000109501.92322.12330913.256801.346307.397705.59660HepG2NONO
WFS1ENSG00000109501.91170.531901837.99920-0.651008.220706.98050HepG2NSUN2
WFS1ENSG00000109501.91334.87730757.281500.817704.214803.10300HepG2PABPC1
WFS1ENSG00000109501.91186.86980983.556200.271002.655701.82290HepG2PARN
WFS1ENSG00000109501.91490.15280925.279300.687407.011706.11800HepG2PCBP1
WFS1ENSG00000109501.91743.57110742.913401.230703.103601.49040HepG2PNPT1
WFS1ENSG00000109501.91449.020001693.71690-0.225102.361001.64020HepG2PRPF4
WFS1ENSG00000109501.91830.72200941.583700.9592029.4963028.08510HepG2PTBP1
WFS1ENSG00000109501.91986.673101226.617900.6956011.1695010.08010HepG2PUF60
WFS1ENSG00000109501.92545.514201302.134600.9670033.2118031.62240HepG2PUM1
WFS1ENSG00000109501.91436.221801880.14010-0.388606.767305.87710HepG2PUS1
WFS1ENSG00000109501.91771.584101019.593400.7969016.9700015.61480HepG2QKI
WFS1ENSG00000109501.91271.678901047.827900.279202.407501.89690HepG2NELFE
WFS1ENSG00000109501.91143.84640976.026000.228802.062201.51970HepG2RECQL
WFS1ENSG00000109501.91118.494301767.75320-0.660406.820605.81730HepG2RPLP0
WFS1ENSG00000109501.91473.62240884.918100.7357011.5143010.33820HepG2SAFB2
WFS1ENSG00000109501.93314.045402293.605300.530903.923203.11430HepG2SF3A3
WFS1ENSG00000109501.91478.517902051.64160-0.472604.974004.04950HepG2SF3B1
WFS1ENSG00000109501.91830.93230980.171300.9014017.8458016.54510HepG2SF3B4
WFS1ENSG00000109501.92126.50790963.380101.142203.704601.96550HepG2SFPQ
WFS1ENSG00000109501.91340.414801031.932000.377205.961005.07250HepG2SMN1
WFS1ENSG00000109501.91692.49370827.055201.033003.970102.80570HepG2SMNDC1
WFS1ENSG00000109501.91817.99000887.301101.034703.769302.18220HepG2SNRNP200
WFS1ENSG00000109501.9774.979901023.14330-0.400802.674702.20770HepG2SRSF1
WFS1ENSG00000109501.91741.246601211.137100.5237010.195209.09630HepG2SRSF5
WFS1ENSG00000109501.91378.253801612.15540-0.226102.419501.76570HepG2SRSF7
WFS1ENSG00000109501.91441.128502349.40540-0.705107.960207.17650HepG2SSB
WFS1ENSG00000109501.9603.456501792.52810-1.5707014.5331012.00700HepG2STAU1
WFS1ENSG00000109501.91186.28110724.713600.710903.274102.06870HepG2STIP1
WFS1ENSG00000109501.9438.12230989.34180-1.175105.316904.42700HepG2SUPV3L1
WFS1ENSG00000109501.9400.32620919.79840-1.2001012.3094011.25630HepG2TAF15
WFS1ENSG00000109501.91514.069602020.53600-0.416304.048403.19090HepG2TARDBP
WFS1ENSG00000109501.91459.86700663.023901.1386010.617108.91400HepG2TFIP11
WFS1ENSG00000109501.9708.36940965.44780-0.446704.488603.88390HepG2TIAL1
WFS1ENSG00000109501.92354.51620974.208101.2730058.7731056.63100HepG2TRIM56
WFS1ENSG00000109501.91823.981301198.395400.605902.861001.97270HepG2TUFM
WFS1ENSG00000109501.92713.059001031.316201.395305.720404.25460HepG2U2AF2
WFS1ENSG00000109501.91465.70510584.325601.326709.807208.37860HepG2UCHL5
WFS1ENSG00000109501.92961.976902034.082500.542106.437105.44440HepG2UPF1
WFS1ENSG00000109501.91154.37730745.892800.630002.528901.48740HepG2XPO5
WFS1ENSG00000109501.91219.766401671.50320-0.454508.922807.83290HepG2ZC3H8
WFS1ENSG00000109501.93098.599502237.093900.469908.489707.66680HepG2ZNF622
WFS1ENSG00000109501.920.748205.050302.038402.394701.78240K562DDX47
WFS1ENSG00000109501.960.669802.316404.7109014.3626012.91770K562EIF2S2
WFS1ENSG00000109501.927.989603.089703.179304.012003.10470K562GRSF1
WFS1ENSG00000109501.911.127501.031103.431801.985501.46870K562HNRNPC
WFS1ENSG00000109501.924.911103.373502.884403.475402.58610K562HSPD1
WFS1ENSG00000109501.917.393601.160503.905703.136602.26420K562RPS19
WFS1ENSG00000109501.94.0174020.85510-2.376102.678301.87590K562SF3A3
WFS1ENSG00000109501.93.8517021.36660-2.471802.991502.02430K562SRPK2
WFS1ENSG00000109501.94.2347022.40870-2.403702.977702.23180K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WFS1 is not available on ENCORE database.





1 RBPs can affect the splicing of WFS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWFS1ENSG00000109501.9chr4+6295984629611562936436293724629676762969160.081000.005350.05596includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WFS1 is not avaliable on ENCORE database.