SIKE1

General Information

Gene Name       : SIKE1
Gene ID             : ENSG00000052723.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SIKE1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIKE1ENSG00000052723.1117.4915.8816.68ENCSR000AEF
HepG2SIKE1ENSG00000052723.1125.0624.0924.57ENCSR985KAT
K562SIKE1ENSG00000052723.1140.6530.8935.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIKE1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIKE1 RNA is bound by 12 proteins.  







eCLIP assay for SIKE1 is not avaliable on ENCORE database.





12 proteins are bound to SIKE1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1115316807115316893-3'-UTR,intron-Distal,intron-Proximal3.034474.91034K562YBX3
chr1115315221115315291-3'-UTR,intron-Distal5.1629025.22171K562FAM120A
chr1115313226115313312-3'-UTR,intron-Distal3.680708.44627K562UPF1
chr1115315616115315658-3'-UTR,intron-Distal3.461846.48512K562FAM120A
chr1115315757115315816-3'-UTR,intron-Distal4.028753.31904K562IGF2BP1
chr1115312125115312203-3'-UTR,intron-Distal3.602767.24422K562PUM2
chr1115315063115315210-3'-UTR,intron-Distal3.6659319.42282K562UPF1
chr1115314451115314487-3'-UTR,intron-Distal3.295616.13685K562UPF1
chr1115315245115315381-3'-UTR,intron-Distal,intron-Proximal3.769035.91795HepG2UPF1
chr1115313560115313596-3'-UTR,intron-Distal4.3435612.69927K562FAM120A
chr1115313424115313485-3'-UTR,intron-Distal3.9814312.24922K562UPF1
chr1115313372115313424-3'-UTR,intron-Distal3.1619414.36439K562UPF1
chr1115314420115314494-3'-UTR,intron-Distal4.9378319.33036K562FAM120A
chr1115312696115312725-3'-UTR,intron-Distal5.145346.32364K562FAM120A
chr1115313343115313419-3'-UTR,intron-Distal6.1665627.63247K562FAM120A
chr1115313430115313471-3'-UTR,intron-Distal6.2210017.71787K562FAM120A
chr1115315123115315196-3'-UTR,intron-Distal6.5183221.05870K562FAM120A
chr1115313340115313372-3'-UTR,intron-Distal3.298728.83660K562UPF1
chr1115314237115314254-3'-UTR,intron-Distal5.402286.60499K562FAM120A
chr1115315648115315657-3'-UTR,intron-Distal3.724434.24288K562UPF1
chr1115315858115315893-3'-UTR,intron-Distal3.201544.87047K562FAM120A
chr1115315291115315350-3'-UTR,intron-Distal,intron-Proximal4.3437525.90361K562FAM120A
chr1115315047115315123-3'-UTR,intron-Distal4.4273515.59783K562FAM120A
chr1115323206115323297-5'-UTR,CDS,intron-Distal,intron-Proximal4.020693.07217HepG2NCBP2
chr1115323139115323276-5'-UTR,CDS,intron-Distal,intron-Proximal5.2536813.46932K562DDX3X
chr1115321830115321907-CDS,intron-Distal,intron-Proximal3.485908.32162K562ZNF622
chr1115321755115321906-CDS,intron-Distal,intron-Proximal3.774867.58784HepG2BCLAF1
chr1115321833115321904-CDS,intron-Distal3.153734.02291HepG2GRWD1
chr1115323075115323139-CDS,intron-Distal,intron-Proximal3.202893.59926K562DDX3X
chr1115319058115319121-CDS,intron-Distal,intron-Proximal3.874884.98250K562AQR
chr1115321765115321830-CDS,intron-Distal,intron-Proximal4.889936.99374K562ZNF622
chr1115322954115323020-intron-Distal3.739113.79442K562AQR
chr1115321624115321699-intron-Distal,intron-Proximal3.166143.94281K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIKE1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIKE1 is not available on ENCORE database.

  • 90 RBPs can affect the levels of SIKE1.  








The Knockdown/knockout RNA-Seq assay for SIKE1 is not available on ENCORE database.





90 RBPs can affect the gene expression of SIKE1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIKE1ENSG00000052723.7745.25950976.43660-0.389803.031902.40030HepG2ACO1
SIKE1ENSG00000052723.71268.179801966.03850-0.632505.812105.07340HepG2AKAP1
SIKE1ENSG00000052723.7736.211801014.55300-0.462703.122502.01760HepG2AKAP8
SIKE1ENSG00000052723.71231.751401626.75600-0.401303.060702.23600HepG2ASCC1
SIKE1ENSG00000052723.7915.925901542.53040-0.7520017.6565016.19880HepG2AUH
SIKE1ENSG00000052723.7670.35560958.70580-0.516203.282302.26360HepG2BCCIP
SIKE1ENSG00000052723.7502.02170833.06060-0.730706.225404.93900HepG2BCLAF1
SIKE1ENSG00000052723.71296.539001043.237900.313502.702001.93980HepG2CALR
SIKE1ENSG00000052723.71342.47660998.926300.426301.988601.34460HepG2CNOT7
SIKE1ENSG00000052723.7664.842701250.58700-0.9115017.6131016.26960HepG2CELF1
SIKE1ENSG00000052723.71049.23500788.975400.411203.369002.62560HepG2DDX21
SIKE1ENSG00000052723.7953.26140772.252900.303702.185501.38390HepG2DDX24
SIKE1ENSG00000052723.7480.42500942.59630-0.972309.996708.63750HepG2DDX55
SIKE1ENSG00000052723.7813.015401617.72980-0.9926012.7199011.51040HepG2DDX6
SIKE1ENSG00000052723.7580.74180825.91020-0.508107.283306.29520HepG2DNAJC2
SIKE1ENSG00000052723.7504.50170676.33330-0.422902.366401.34320HepG2EFTUD2
SIKE1ENSG00000052723.7510.402001555.28430-1.6075033.3684031.47060HepG2EIF2S1
SIKE1ENSG00000052723.7506.904101673.41080-1.7230027.4609025.47360HepG2EIF4B
SIKE1ENSG00000052723.71142.160501326.63590-0.216002.161501.40600HepG2EIF4G1
SIKE1ENSG00000052723.72309.403101771.066100.382806.148805.31260HepG2ETF1
SIKE1ENSG00000052723.71165.92290954.296100.288902.162201.42420HepG2EWSR1
SIKE1ENSG00000052723.7754.269701083.86330-0.523003.146301.95540HepG2FUS
SIKE1ENSG00000052723.71235.417901734.05050-0.489104.361603.50680HepG2FXR1
SIKE1ENSG00000052723.7861.189401608.67960-0.9015011.5496010.23850HepG2G3BP1
SIKE1ENSG00000052723.7469.22620924.58650-0.978506.834705.09240HepG2GRSF1
SIKE1ENSG00000052723.7725.32170935.74530-0.367502.592901.91950HepG2HNRNPC
SIKE1ENSG00000052723.71312.817601628.71560-0.311102.228201.59640HepG2HNRNPK
SIKE1ENSG00000052723.71028.525601225.08850-0.252303.001002.30240HepG2HNRNPL
SIKE1ENSG00000052723.7591.18060858.56260-0.538302.724901.78160HepG2HNRNPM
SIKE1ENSG00000052723.7594.07670929.55900-0.6459010.600909.47800HepG2HNRNPU
SIKE1ENSG00000052723.71118.468201635.22090-0.548005.230904.32870HepG2IGF2BP2
SIKE1ENSG00000052723.7749.57110949.51430-0.341104.334103.43720HepG2ILF2
SIKE1ENSG00000052723.71213.945201644.69060-0.438102.643001.66640HepG2KHSRP
SIKE1ENSG00000052723.71070.938001599.66880-0.578902.131801.41020HepG2LARP4
SIKE1ENSG00000052723.7426.71740689.27540-0.691803.515602.33410HepG2METAP2
SIKE1ENSG00000052723.71337.801101785.50630-0.416503.073702.40810HepG2NCBP2
SIKE1ENSG00000052723.7634.574601333.52940-1.0714025.4778023.33940HepG2NOL12
SIKE1ENSG00000052723.7397.77880865.49540-1.121607.865705.99640HepG2NONO
SIKE1ENSG00000052723.71205.321801590.21780-0.399802.962802.21810HepG2PABPC4
SIKE1ENSG00000052723.7766.94290920.10890-0.262702.181601.42140HepG2PARN
SIKE1ENSG00000052723.71110.908501498.56110-0.431806.749205.86590HepG2PCBP1
SIKE1ENSG00000052723.7658.97520829.09300-0.331302.826002.08240HepG2PPIL4
SIKE1ENSG00000052723.7889.695401524.79780-0.7772018.2288017.05750HepG2PTBP1
SIKE1ENSG00000052723.71115.269901351.22220-0.276903.785703.11560HepG2PUM1
SIKE1ENSG00000052723.71108.489301350.26530-0.284602.557401.91220HepG2PUM2
SIKE1ENSG00000052723.71100.460301696.99020-0.6249012.8640011.85630HepG2NELFE
SIKE1ENSG00000052723.71247.248301580.44930-0.341604.561103.79610HepG2RECQL
SIKE1ENSG00000052723.7465.18680719.35280-0.628904.349903.38810HepG2RRP9
SIKE1ENSG00000052723.7651.87460827.81560-0.344703.491502.78330HepG2SAFB2
SIKE1ENSG00000052723.7462.47030643.17520-0.475902.737701.80450HepG2SERBP1
SIKE1ENSG00000052723.7784.565001308.87220-0.738406.477905.42140HepG2SF3A3
SIKE1ENSG00000052723.7718.602501042.52170-0.536804.942104.02160HepG2SF3B1
SIKE1ENSG00000052723.71093.395201587.59050-0.538009.837908.82390HepG2SF3B4
SIKE1ENSG00000052723.7684.99930965.37650-0.495007.141306.18380HepG2SMN1
SIKE1ENSG00000052723.71123.743901657.06840-0.560309.047608.30260HepG2SRSF1
SIKE1ENSG00000052723.71024.530901256.77420-0.294803.348002.67090HepG2SRSF5
SIKE1ENSG00000052723.7864.600701348.08560-0.6408013.5783012.52030HepG2SRSF9
SIKE1ENSG00000052723.7934.411101429.34820-0.6132013.7935012.57940HepG2SUCLG1
SIKE1ENSG00000052723.7429.57820938.35710-1.1272013.0994011.81000HepG2SUPV3L1
SIKE1ENSG00000052723.71768.263101489.348100.247602.210301.69930HepG2TAF15
SIKE1ENSG00000052723.7722.133701026.53320-0.507404.401903.51540HepG2TARDBP
SIKE1ENSG00000052723.7719.96000903.25410-0.327202.610102.12170HepG2TIAL1
SIKE1ENSG00000052723.7547.47160911.31360-0.7352013.2193012.11840HepG2TRIM56
SIKE1ENSG00000052723.7706.603601316.19330-0.8974010.520008.84960HepG2UBE2L3
SIKE1ENSG00000052723.7347.15950554.32810-0.675105.159504.11540HepG2UCHL5
SIKE1ENSG00000052723.7631.48850923.70920-0.548704.092703.21900HepG2XRN2
SIKE1ENSG00000052723.7874.966001276.62490-0.5450011.0599010.14650HepG2ZNF622
SIKE1ENSG00000052723.71816.273202762.97050-0.6052015.9572014.70910K562AGGF1
SIKE1ENSG00000052723.72095.984002874.96460-0.455905.436504.50330K562AKAP8L
SIKE1ENSG00000052723.72561.537503016.47040-0.235902.580201.69990K562ATP5C1
SIKE1ENSG00000052723.71582.999401955.98290-0.305204.003702.83340K562BCLAF1
SIKE1ENSG00000052723.72619.822603302.00360-0.333904.088702.61590K562CCDC124
SIKE1ENSG00000052723.72743.889903339.37280-0.283403.680702.39620K562CPEB4
SIKE1ENSG00000052723.71216.674902291.04960-0.9131020.3983018.26100K562CPSF6
SIKE1ENSG00000052723.71039.181501483.90410-0.514006.802805.04180K562CSTF2
SIKE1ENSG00000052723.71938.256402321.68160-0.260402.965301.71190K562DDX21
SIKE1ENSG00000052723.71488.945501840.97850-0.306202.828301.77510K562DDX3X
SIKE1ENSG00000052723.71251.356502022.06450-0.6923017.1775014.22300K562EIF2S1
SIKE1ENSG00000052723.71655.329602263.14480-0.451205.235704.29150K562EIF2S2
SIKE1ENSG00000052723.71671.590001983.32320-0.246702.361401.62320K562EIF3G
SIKE1ENSG00000052723.71212.807401732.03400-0.514108.000205.89770K562EIF4B
SIKE1ENSG00000052723.71285.636401678.85300-0.385003.283201.85130K562EWSR1
SIKE1ENSG00000052723.71878.143802531.60010-0.430704.615803.49970K562FIP1L1
SIKE1ENSG00000052723.71382.127801814.47050-0.392704.920702.38820K562FUBP3
SIKE1ENSG00000052723.73089.130502043.000400.596405.108504.08120K562G3BP2
SIKE1ENSG00000052723.71549.477603016.13350-0.9609012.8188011.17200K562GRSF1
SIKE1ENSG00000052723.72986.611102214.579300.431404.024902.49620K562HNRNPK
SIKE1ENSG00000052723.72603.585503122.97810-0.262402.331901.37160K562HNRNPL
SIKE1ENSG00000052723.71549.569602082.23070-0.426303.387502.35000K562HNRNPM
SIKE1ENSG00000052723.72502.239803051.16630-0.286102.765201.93970K562KIF1C
SIKE1ENSG00000052723.71598.235602217.35440-0.472409.839908.41750K562MTPAP
SIKE1ENSG00000052723.71134.594801615.79340-0.510104.396402.65860K562NONO
SIKE1ENSG00000052723.72061.932102873.79970-0.479005.411604.20270K562PPIG
SIKE1ENSG00000052723.71950.024202851.40130-0.548206.069405.30330K562PUS1
SIKE1ENSG00000052723.72170.756402778.07430-0.355904.055303.35440K562RBM15
SIKE1ENSG00000052723.71847.641702431.00110-0.395906.157704.97970K562SF3A3
SIKE1ENSG00000052723.72894.533502490.607100.216703.214702.21330K562SRPK2
SIKE1ENSG00000052723.71683.337602095.47770-0.316002.527101.53090K562SRSF5
SIKE1ENSG00000052723.71464.696502045.82750-0.482108.032905.75630K562SSB
SIKE1ENSG00000052723.71186.285801546.10710-0.382202.466701.51330K562SUPV3L1
SIKE1ENSG00000052723.72024.079501596.810000.342003.747702.79150K562SYNCRIP
SIKE1ENSG00000052723.71675.278502246.09100-0.423002.945202.21530K562TARDBP
SIKE1ENSG00000052723.71699.630002166.54560-0.350202.714601.90550K562TIA1
SIKE1ENSG00000052723.72212.779202574.84670-0.218602.675001.42900K562TROVE2
SIKE1ENSG00000052723.73784.081404753.42360-0.329003.195601.68060K562UBE2L3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIKE1 is not available on ENCORE database.





5 RBPs can affect the splicing of SIKE1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESIKE1ENSG00000052723.7chr1-115322730115322836115321727115321905115323069115323255-0.108000.000600.01378excludedK562SRSF1
SESIKE1ENSG00000052723.7chr1-115318966115319080115315395115316993115321762115321905-0.169000.000000.00007excludedK562SF3B4
SESIKE1ENSG00000052723.7chr1-115318966115319080115316965115316993115321762115321905-0.127000.000010.00047excludedK562AKAP8L
SESIKE1ENSG00000052723.7chr1-115322730115322836115321762115321905115323069115323298-0.084000.000250.00377excludedK562AQR
SESIKE1ENSG00000052723.7chr1-1153215521153216751153190041153190801153217621153219050.121000.000010.00051includedK562HNRNPC
A3SSSIKE1ENSG00000052723.7chr1-1153217621153220081153217621153219051153227301153228360.125000.000000.00000longerK562AQR
RISIKE1ENSG00000052723.7chr1-1153227301153231161153227301153228361153231111153231160.146000.014660.07524includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SIKE1 is not avaliable on ENCORE database.