SACM1L

General Information

Gene Name       : SACM1L
Gene ID             : ENSG00000211456.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SACM1L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SACM1LENSG00000211456.1021.6119.3120.46ENCSR000AEF
HepG2SACM1LENSG00000211456.1014.1024.2319.16ENCSR985KAT
K562SACM1LENSG00000211456.1032.7333.9033.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SACM1L is not avaliable on ENCORE database.



Proteins bound to RNA
  • SACM1L RNA is bound by 31 proteins.  







eCLIP assay for SACM1L is not avaliable on ENCORE database.





31 proteins are bound to SACM1L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr34578607445786162+3'-UTR3.750658.50021K562YBX3
chr34578001745780127+3'-UTR,CDS,intron-Proximal4.063164.84268K562SF3B4
chr34578668045786722+3'-UTR5.2592922.55160K562PUM2
chr34577912345779145+3'-UTR,CDS,intron-Proximal3.065883.94979HepG2BCLAF1
chr34578583445785864+3'-UTR5.155359.34312K562PUM2
chr34577926245779339+3'-UTR,CDS,intron-Proximal3.334643.99124HepG2PPIG
chr34578007345780164+3'-UTR,CDS,intron-Proximal4.054084.01763HepG2GRWD1
chr34578668345786763+3'-UTR3.767293.22721K562YBX3
chr34578628545786331+3'-UTR4.4066012.07925K562PUM2
chr34578008145780166+3'-UTR,CDS,intron-Proximal3.474666.43326K562UCHL5
chr34576352645763582+3'-UTR,CDS,intron-Proximal3.698864.09885HepG2BCLAF1
chr34576354145763616+3'-UTR,CDS,intron-Proximal4.757138.44604HepG2PRPF8
chr34578663745786680+3'-UTR3.8613714.79105K562PUM2
chr34578530545785439+3'-UTR4.5675811.85921K562ZC3H11A
chr34578027245780334+3'-UTR,CDS,intron-Proximal4.523403.45943HepG2BCLAF1
chr34576103045761087+3'-UTR,CDS3.008143.55800HepG2BCLAF1
chr34574492645745025+3'-UTR,5'-UTR,CDS,intron-Proximal3.829536.80284K562DDX24
chr34575467445754728+3'-UTR,5'-UTR,CDS,intron-Proximal3.334665.31369K562PRPF8
chr34574487445744958+3'-UTR,5'-UTR,CDS,intron-Proximal4.732565.63851K562SF3B4
chr34574492745745028+3'-UTR,5'-UTR,CDS,intron-Proximal4.783955.52963HepG2PPIG
chr34578516245785259+3'-UTR4.196734.49401HepG2STAU2
chr34576442645764511+3'-UTR,CDS,intron-Proximal3.445203.94787K562AQR
chr34578659545786637+3'-UTR3.546149.19739K562PUM2
chr34573092645730984+5'-UTR,CDS,intron-Distal3.859703.01994HepG2GTF2F1
chr34573090745730997+5'-UTR,CDS,intron-Distal,intron-Proximal3.606897.19472K562GTF2F1
chr34573090845730997+5'-UTR,CDS,intron-Distal,intron-Proximal3.714427.16836HepG2NCBP2
chr34574662645746702+5'-UTR,CDS,intron-Proximal3.331594.85828HepG2BCLAF1
chr34573101845731130+5'-UTR,intron-Distal,intron-Proximal5.3727031.96907K562AKAP8L
chr34573090045730991+5'-UTR,CDS,intron-Distal,intron-Proximal3.113636.45752K562DDX6
chr34573093845730990+5'-UTR,CDS,intron-Distal,intron-Proximal3.550786.14554K562DROSHA
chr34573086245730988+5'-UTR,CDS,intron-Distal3.7059611.26736K562DDX3X
chr34573091145730999+5'-UTR,CDS,intron-Distal,intron-Proximal3.2214512.92162K562AKAP8L
chr34575104945751142+5'-UTR,CDS,intron-Proximal4.950114.34038HepG2BCLAF1
chr34576330145763367+intron-Distal3.021324.74253K562KHSRP
chr34576118545761306+intron-Distal,intron-Proximal4.239223.75546HepG2KHSRP
chr34576336745763431+intron-Distal,intron-Proximal3.466225.14864K562KHSRP
chr34576118345761205+intron-Distal,intron-Proximal3.682845.32884K562KHSRP
chr34576122745761263+intron-Distal5.0895817.06553K562KHSRP
chr34576828045768339+intron-Distal4.944255.76606K562EXOSC5
chr34575060945750660+intron-Distal3.300237.20875K562KHSRP
chr34577869445778800+intron-Distal4.5377410.35072HepG2RBFOX2
chr34575800745758078+intron-Distal4.345824.50934HepG2RBFOX2
chr34576888445768959+intron-Distal3.174606.00234K562KHSRP
chr34574971845749780+intron-Distal4.733075.11833K562DGCR8
chr34574874545748796+intron-Distal4.499144.64001HepG2U2AF2
chr34576580445765874+intron-Distal4.139654.38266K562TARDBP
chr34577870045778819+intron-Distal4.052963.84437HepG2PRPF4
chr34576364545763715+intron-Distal,intron-Proximal4.903715.70555K562PRPF8
chr34576126345761320+intron-Distal5.9865417.21040K562KHSRP
chr34573342245733568+intron-Distal4.201823.09122HepG2PTBP1
chr34578489845784935+intron-Distal,intron-Proximal3.409884.52210K562KHSRP
chr34577875045778832+intron-Distal3.725606.88394K562RBFOX2
chr34574981145749900+intron-Distal3.5575210.88606K562KHSRP
chr34575510745755211+intron-Distal3.195845.74374K562KHSRP
chr34575051245750591+intron-Distal3.561218.32500K562KHSRP
chr34576359845763721+intron-Distal,intron-Proximal3.693076.59733K562KHSRP
chr34573338245733507+intron-Distal3.601835.09669HepG2QKI
chr34577494745775028+intron-Distal3.348484.05663K562HNRNPL
chr34575472845754790+intron-Distal,intron-Proximal4.974715.70555K562PRPF8
chr34575059145750609+intron-Distal3.841047.82071K562KHSRP
chr34577736345777474+intron-Distal4.084275.16744K562HNRNPC
chr34576895945769038+intron-Distal3.652317.84449K562KHSRP
chr34575818145758287+intron-Distal4.472704.43431HepG2RBFOX2
chr34576900045769025+intron-Distal4.315353.01445K562EXOSC5
chr34576875545768799+intron-Distal4.834696.08869K562EXOSC5
chr34576746745767542+intron-Distal5.203946.41216K562EXOSC5
chr34576120545761227+intron-Distal3.903467.26586K562KHSRP
chr34575674545756842+intron-Distal3.939003.49011K562KHSRP
chr34574990045749928+intron-Distal3.958745.35459K562KHSRP
chr34575526245755413+intron-Distal3.025259.18614K562KHSRP
chr34575056245750636+intron-Distal3.263613.59190K562TIA1
chr34576113045761182+intron-Proximal5.368268.90415K562KHSRP
chr34577933645779419+intron-Proximal5.7294410.84943K562AQR
chr34575470245754783+intron-Proximal4.711533.61992K562RBM22
chr34576109345761130+intron-Proximal3.483575.32884K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SACM1L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SACM1L is not available on ENCORE database.

  • 82 RBPs can affect the levels of SACM1L.  








The Knockdown/knockout RNA-Seq assay for SACM1L is not available on ENCORE database.





82 RBPs can affect the gene expression of SACM1L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SACM1LENSG00000211456.6454.81990791.93410-0.8001013.1119011.60770HepG2AKAP8L
SACM1LENSG00000211456.6900.162201260.53140-0.485807.348606.31730HepG2AUH
SACM1LENSG00000211456.6474.89050749.59270-0.658504.145003.00150HepG2BCCIP
SACM1LENSG00000211456.6648.03530825.68190-0.349502.257101.71120HepG2BOP1
SACM1LENSG00000211456.6734.469301033.88940-0.493303.031102.00850HepG2CCAR1
SACM1LENSG00000211456.6517.48620694.81380-0.425102.393001.36690HepG2CPSF7
SACM1LENSG00000211456.6534.04520662.70720-0.311402.228601.31720HepG2YBX3
SACM1LENSG00000211456.6857.320801109.84940-0.372505.001404.04760HepG2DAZAP1
SACM1LENSG00000211456.6807.59680586.587800.461203.379702.63500HepG2DDX21
SACM1LENSG00000211456.61510.208201088.626300.472103.836003.11080HepG2DDX3X
SACM1LENSG00000211456.6410.67410736.97040-0.843606.512005.38510HepG2DDX55
SACM1LENSG00000211456.6602.34990935.06700-0.634504.883904.08460HepG2DDX6
SACM1LENSG00000211456.6500.51060650.77150-0.378803.086102.34750HepG2DNAJC21
SACM1LENSG00000211456.6456.67440644.96290-0.498105.954505.05090HepG2DNAJC2
SACM1LENSG00000211456.6415.92860898.98740-1.1120014.2532012.97730HepG2EIF2S1
SACM1LENSG00000211456.6778.91650993.52780-0.351101.830901.30650HepG2EIF4A3
SACM1LENSG00000211456.6614.32410967.26050-0.654904.373103.51950HepG2EIF4B
SACM1LENSG00000211456.6653.748701019.96790-0.6417010.226108.64120HepG2HNRNPA2B1
SACM1LENSG00000211456.6644.818601010.99750-0.6488012.3112010.98460HepG2HNRNPL
SACM1LENSG00000211456.6464.25860725.94650-0.644908.924807.88390HepG2HNRNPU
SACM1LENSG00000211456.6488.93550741.53380-0.600908.879407.63840HepG2ILF2
SACM1LENSG00000211456.6874.636801100.52260-0.331403.045202.24560HepG2NOL12
SACM1LENSG00000211456.6969.52340708.793800.451802.300301.35260HepG2PCBP2
SACM1LENSG00000211456.6502.22720647.48990-0.366502.924002.16870HepG2PPIL4
SACM1LENSG00000211456.6715.49930568.702400.331202.032401.33560HepG2PRPF8
SACM1LENSG00000211456.6885.072001114.37210-0.332402.890002.20560HepG2PUM2
SACM1LENSG00000211456.6702.88410950.80280-0.435904.334403.57780HepG2QKI
SACM1LENSG00000211456.6972.58230684.074200.507602.305701.65870HepG2RAVER1
SACM1LENSG00000211456.6613.57800893.23900-0.541805.722504.54580HepG2RBM15
SACM1LENSG00000211456.6841.080001209.64750-0.524307.200506.45610HepG2RBM22
SACM1LENSG00000211456.61072.19370862.904800.313202.307601.68670HepG2RBM25
SACM1LENSG00000211456.6627.74390800.88490-0.351402.471901.82050HepG2RPLP0
SACM1LENSG00000211456.6306.34550453.80600-0.566903.579802.88990HepG2RPS19
SACM1LENSG00000211456.6498.57030646.49960-0.374903.401202.70030HepG2SAFB2
SACM1LENSG00000211456.61293.97210878.134800.559203.650502.87230HepG2SF3A3
SACM1LENSG00000211456.6502.60380811.68980-0.691506.749405.68850HepG2SF3B1
SACM1LENSG00000211456.61195.05910914.018900.386704.505603.77860HepG2SF3B4
SACM1LENSG00000211456.6860.999301007.27900-0.226402.048401.42750HepG2SLBP
SACM1LENSG00000211456.6602.93740753.94830-0.322502.808502.16080HepG2SMN1
SACM1LENSG00000211456.61622.00270954.028900.7656017.1743016.20910HepG2SRSF1
SACM1LENSG00000211456.6293.84180575.29210-0.9693010.411208.69850HepG2SUPT6H
SACM1LENSG00000211456.6466.95010705.47000-0.595306.303605.60460HepG2TIAL1
SACM1LENSG00000211456.6474.85490711.69340-0.583807.536306.68290HepG2TRIM56
SACM1LENSG00000211456.6988.45390728.705700.439703.403102.71200HepG2U2AF1
SACM1LENSG00000211456.6760.684001086.32420-0.514103.626902.66130HepG2UBE2L3
SACM1LENSG00000211456.6517.40840800.45980-0.629508.371106.66340HepG2UTP18
SACM1LENSG00000211456.6893.85370751.872400.249501.851001.33980HepG2UTP3
SACM1LENSG00000211456.6420.87490722.24320-0.779106.230605.15670HepG2XRN2
SACM1LENSG00000211456.61205.884301594.61430-0.403103.820902.01740K562AKAP1
SACM1LENSG00000211456.62078.281202973.18370-0.516606.349605.52160K562AQR
SACM1LENSG00000211456.61325.290301777.37170-0.423405.926203.88740K562BCCIP
SACM1LENSG00000211456.6441.71010653.38520-0.564804.493503.08660K562CCAR1
SACM1LENSG00000211456.61140.775301524.38670-0.418204.415403.42620K562CPSF6
SACM1LENSG00000211456.61043.102901302.95490-0.320902.929701.84200K562CSTF2
SACM1LENSG00000211456.62086.077402518.23770-0.271603.614102.88170K562DDX47
SACM1LENSG00000211456.61213.431701774.63050-0.5484010.724208.28420K562EIF2S1
SACM1LENSG00000211456.6455.82550664.61940-0.544002.602801.62980K562EIF3A
SACM1LENSG00000211456.61195.552501596.75590-0.417504.241803.26670K562EIF3G
SACM1LENSG00000211456.61196.482301520.08940-0.345403.806302.41930K562EIF4B
SACM1LENSG00000211456.61414.166701908.50190-0.432504.359503.27960K562FIP1L1
SACM1LENSG00000211456.62433.994501798.961200.436102.929002.19890K562G3BP2
SACM1LENSG00000211456.6986.667001362.41060-0.465502.855701.40780K562GEMIN5
SACM1LENSG00000211456.61930.117302766.00010-0.519106.944405.73950K562GRSF1
SACM1LENSG00000211456.6993.904401406.60500-0.501005.538904.72310K562HNRNPC
SACM1LENSG00000211456.61002.008801256.01400-0.326002.470501.40280K562HNRNPF
SACM1LENSG00000211456.61829.903002275.76520-0.314602.964501.86650K562HNRNPL
SACM1LENSG00000211456.61471.316701941.25610-0.399905.371904.11320K562HNRNPU
SACM1LENSG00000211456.62047.336702587.61770-0.337902.908102.09350K562HSPD1
SACM1LENSG00000211456.61676.040502156.74680-0.363802.574601.43730K562IGF2BP3
SACM1LENSG00000211456.6892.419901426.43480-0.676607.730505.10760K562LIN28B
SACM1LENSG00000211456.61479.198002224.77690-0.588804.992203.70940K562MATR3
SACM1LENSG00000211456.6645.249201420.65500-1.1386023.3449020.78890K562METAP2
SACM1LENSG00000211456.61405.492901724.34490-0.295003.920202.97200K562MTPAP
SACM1LENSG00000211456.62192.318501525.542700.523003.903702.80590K562NAA15
SACM1LENSG00000211456.61499.613201915.89190-0.353406.857805.75560K562NSUN2
SACM1LENSG00000211456.61030.978401384.80490-0.425703.269501.67140K562NUSAP1
SACM1LENSG00000211456.61378.991102166.43020-0.651708.884407.20240K562PPIG
SACM1LENSG00000211456.6861.073001261.14480-0.550505.558204.21050K562PSIP1
SACM1LENSG00000211456.64573.361303786.942400.272102.948001.84370K562PUM1
SACM1LENSG00000211456.62547.708801815.601000.488704.826104.13430K562PUS1
SACM1LENSG00000211456.62120.665801768.969600.261502.635302.05530K562RBM15
SACM1LENSG00000211456.61567.685002077.21890-0.406002.334801.56770K562RBM22
SACM1LENSG00000211456.6899.277901150.51590-0.355403.000601.96620K562RCC2
SACM1LENSG00000211456.61430.178701827.96800-0.354003.133901.32340K562RECQL
SACM1LENSG00000211456.6997.566801347.24620-0.433502.255601.52140K562RPS19
SACM1LENSG00000211456.6718.559401090.67030-0.602006.315404.59100K562SRFBP1
SACM1LENSG00000211456.6782.167701023.47620-0.387903.181502.03610K562SRSF4
SACM1LENSG00000211456.61296.461901069.336700.277802.245601.50490K562SYNCRIP
SACM1LENSG00000211456.6767.117901213.02440-0.661106.568005.07330K562TIAL1
SACM1LENSG00000211456.6944.900801288.55280-0.447504.158402.94960K562TRIM56
SACM1LENSG00000211456.62256.624601744.924800.370902.305101.31920K562U2AF1
SACM1LENSG00000211456.61407.231401738.25630-0.304802.717501.84850K562WDR3
SACM1LENSG00000211456.61544.764601807.59380-0.226702.742201.89930K562WDR43
SACM1LENSG00000211456.6983.770601379.80720-0.488103.123601.81170K562XRN2
SACM1LENSG00000211456.62772.420703349.30270-0.272702.312301.53520K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SACM1L is not available on ENCORE database.





16 RBPs can affect the splicing of SACM1L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESACM1LENSG00000211456.6chr3+457482714574839945746626457467014575098945751139-0.214000.000010.00038excludedK562SF3B4
SESACM1LENSG00000211456.6chr3+457767264577686545773544457736434577907445779144-0.075000.000720.01606excludedK562SF3B4
SESACM1LENSG00000211456.6chr3+457767374577686545773544457736434577907445779144-0.118000.003650.09696excludedK562PRPF8
SESACM1LENSG00000211456.6chr3+4573183945731879457307324573098945744929457450270.143000.000000.00191includedK562TIA1
SESACM1LENSG00000211456.6chr3+4573183945731879457308484573098945744929457450270.099000.000370.05911includedK562MATR3
SESACM1LENSG00000211456.6chr3+457727924577287245764966457650354577354445773643-0.066000.001060.03324excludedK562AKAP8L
SESACM1LENSG00000211456.6chr3+4573183945731879457307324573098945744929457450270.126000.000010.00555includedK562PCBP1
SESACM1LENSG00000211456.6chr3+457318394573187945730732457309894574492945745027-0.063000.003100.03606excludedHepG2U2AF2
SESACM1LENSG00000211456.6chr3+457767264577686545773544457736434577907445779144-0.068000.000090.00161excludedK562AQR
SESACM1LENSG00000211456.6chr3+457482714574839945746626457467014575098945751139-0.155000.001380.09342excludedK562SUPV3L1
SESACM1LENSG00000211456.6chr3+457767374577686545773544457736434577907445779144-0.057000.007850.08744excludedK562PUS1
SESACM1LENSG00000211456.6chr3+457482714574839945746626457467014575098945751139-0.197000.000230.00583excludedK562U2AF2
SESACM1LENSG00000211456.6chr3+4573183945731879457308484573098945744929457450270.121000.000010.00119includedK562TARDBP
SESACM1LENSG00000211456.6chr3+457767264577686545773544457736434577907445779144-0.073000.000180.00700excludedK562RBM15
SESACM1LENSG00000211456.6chr3+457318394573189445730732457309894574492945745027-0.067000.002110.04938excludedK562AGGF1
SESACM1LENSG00000211456.6chr3+457767264577686545773544457736434577907445779144-0.055000.002720.05915excludedK562AGGF1
SESACM1LENSG00000211456.6chr3+4573183945731879457307324573098945744929457450270.103000.000530.02474includedK562SF3B1
SESACM1LENSG00000211456.6chr3+4573183945731879457307324573098945744929457450270.125000.001520.05384includedHepG2HNRNPC
SESACM1LENSG00000211456.6chr3+4573183945731879457307324573098945744929457450270.137000.000000.00030includedK562PTBP1
A3SSSACM1LENSG00000211456.6chr3+4576493945765035457649664576503545764360457644470.094000.000000.00000longerK562AQR
MXESACM1LENSG00000211456.6chr3+45773544457736434577672645776865457649664576503545779074457791440.064000.000130.007031includedK562RBM15
MXESACM1LENSG00000211456.6chr3+45773544457736434577672645776865457649664576503545779074457791440.052000.000300.007881includedK562PUS1
MXESACM1LENSG00000211456.6chr3+45764939457649994577279245772872457643604576444745773544457736430.102000.000000.000001includedK562AQR
MXESACM1LENSG00000211456.6chr3+45764939457650354577279245772872457643604576444745773544457736430.119000.000000.000001includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SACM1L is not avaliable on ENCORE database.