RNF8

General Information

Gene Name       : RNF8
Gene ID             : ENSG00000112130.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RNF8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RNF8ENSG00000112130.1622.4717.1219.80ENCSR000AEF
HepG2RNF8ENSG00000112130.1624.6838.4231.55ENCSR985KAT
K562RNF8ENSG00000112130.1630.4031.6131.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RNF8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RNF8 RNA is bound by 14 proteins.  







eCLIP assay for RNF8 is not avaliable on ENCORE database.





14 proteins are bound to RNF8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63735882837358929+3'-UTR5.073985.74792HepG2SUB1
chr63734470137344736+3'-UTR,CDS,intron-Proximal3.819364.09885HepG2BCLAF1
chr63734244037342487+3'-UTR,CDS,intron-Distal,intron-Proximal3.366434.44630K562ZNF622
chr63734473537344792+3'-UTR,CDS3.559624.40383K562UCHL5
chr63733654837336592+3'-UTR,5'-UTR,CDS3.872825.35703HepG2BCLAF1
chr63734243137342551+3'-UTR,CDS,intron-Distal,intron-Proximal3.823594.00320K562AQR
chr63734243737342486+3'-UTR,CDS,intron-Distal,intron-Proximal3.998595.79432HepG2BCLAF1
chr63734470037344740+3'-UTR,CDS,intron-Proximal4.253124.13344K562GRWD1
chr63734892437349058+3'-UTR,CDS,intron-Distal,intron-Proximal3.073904.88466K562UCHL5
chr63733656937336671+3'-UTR,5'-UTR,CDS4.255567.93948K562ZNF622
chr63735852437358608+3'-UTR,CDS3.917833.05875K562RBM15
chr63734473637344802+3'-UTR,CDS4.723045.23259HepG2BCLAF1
chr63733655037336625+3'-UTR,5'-UTR,CDS4.139044.01763HepG2GRWD1
chr63734892537349000+3'-UTR,CDS,intron-Distal,intron-Proximal4.241284.91614HepG2GRWD1
chr63733632037336429+3'-UTR,5'-UTR,CDS3.015653.09090K562GRWD1
chr63733633537336436+3'-UTR,5'-UTR,CDS4.351554.21087HepG2GRWD1
chr63734241137342493+3'-UTR,CDS,intron-Distal,intron-Proximal3.340224.35124K562ZNF800
chr63733638637336446+3'-UTR,5'-UTR,CDS3.665304.46864HepG2BCLAF1
chr63733629837336433+3'-UTR,5'-UTR,CDS5.8718914.11692K562ZNF622
chr63734239537342491+3'-UTR,CDS,intron-Distal,intron-Proximal3.751685.03432K562GRWD1
chr63734469837344735+3'-UTR,CDS,intron-Proximal3.220584.30396K562UCHL5
chr63733646737336538+3'-UTR,5'-UTR,CDS4.189886.81811K562UCHL5
chr63734242837342499+3'-UTR,CDS,intron-Distal,intron-Proximal3.062483.50639HepG2PPIG
chr63734240237342488+3'-UTR,CDS,intron-Distal,intron-Proximal4.394068.92108K562UCHL5
chr63733644637336534+3'-UTR,5'-UTR,CDS4.427588.15024HepG2BCLAF1
chr63732176537321838+5'-UTR4.157926.30252K562DDX3X
chr63733695737336995+5'-UTR,CDS,intron-Proximal3.824315.80935K562ZNF622
chr63732183637321932+5'-UTR,intron-Proximal3.342624.27210HepG2NCBP2
chr63732186037321960+5'-UTR,CDS,intron-Proximal4.634716.05264HepG2DDX3X
chr63733926837339376+5'-UTR,CDS,intron-Proximal4.103315.97994K562AQR
chr63733928637339351+5'-UTR,CDS,intron-Proximal3.744027.95479K562ZNF622
chr63733683537336911+5'-UTR,CDS4.144587.51551K562UCHL5
chr63732829337328342+5'-UTR,CDS3.313523.12941K562UCHL5
chr63732822037328293+5'-UTR,CDS,intron-Proximal4.874305.86954K562UCHL5
chr63732821937328315+5'-UTR,CDS,intron-Proximal4.469124.91614HepG2GRWD1
chr63733928237339358+5'-UTR,CDS,intron-Proximal3.135433.18789HepG2BCLAF1
chr63732183337321982+5'-UTR,CDS,intron-Proximal4.863078.55937HepG2GRWD1
chr63733691837337000+5'-UTR,CDS,intron-Proximal5.5190511.40157K562UCHL5
chr63733928537339355+5'-UTR,CDS,intron-Proximal3.772138.13606K562UCHL5
chr63733687237336936+5'-UTR,CDS3.086343.34231K562RBM15
chr63732198237322054+CDS,intron-Distal,intron-Proximal4.007524.01763HepG2GRWD1
chr63732199537322050+CDS,intron-Distal3.202103.07653K562ZNF622
chr63735817837358289+intron-Distal4.275209.01522HepG2RBFOX2
chr63732222937322379+intron-Distal3.812904.76009HepG2PRPF4
chr63735351337353594+intron-Distal3.233883.59803HepG2PTBP1
chr63735820237358272+intron-Distal4.044703.27618K562RBFOX2
chr63735351637353595+intron-Distal4.461843.55787K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RNF8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RNF8 is not available on ENCORE database.

  • 88 RBPs can affect the levels of RNF8.  








The Knockdown/knockout RNA-Seq assay for RNF8 is not available on ENCORE database.





88 RBPs can affect the gene expression of RNF8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RNF8ENSG00000112130.121059.284501336.65150-0.335501.745501.31250HepG2AKAP1
RNF8ENSG00000112130.12490.95990696.54610-0.504603.147902.03910HepG2AKAP8
RNF8ENSG00000112130.12469.18380681.66940-0.538902.866501.91110HepG2BCCIP
RNF8ENSG00000112130.12751.174201142.55150-0.605004.381803.13980HepG2CCAR1
RNF8ENSG00000112130.12647.624201050.77150-0.698206.586605.42850HepG2CIRBP
RNF8ENSG00000112130.12512.74490891.71170-0.798308.639507.48250HepG2CPSF6
RNF8ENSG00000112130.12417.01040553.72910-0.409103.078702.00340HepG2YBX3
RNF8ENSG00000112130.12446.79970947.41400-1.0844022.3746020.90750HepG2CELF1
RNF8ENSG00000112130.12247.67110670.19720-1.4362016.2642014.60650HepG2DDX55
RNF8ENSG00000112130.12997.74680785.055600.345802.322801.39730HepG2DDX5
RNF8ENSG00000112130.12736.409601099.76270-0.578604.385103.62130HepG2DDX6
RNF8ENSG00000112130.12737.057001057.44250-0.520703.879703.18470HepG2EIF2S1
RNF8ENSG00000112130.12501.36690678.68040-0.436903.224401.95340HepG2EIF2S2
RNF8ENSG00000112130.12358.87920528.51390-0.558402.525901.65770HepG2EIF3D
RNF8ENSG00000112130.12616.272001137.69760-0.884507.639906.52640HepG2EIF4B
RNF8ENSG00000112130.121076.875001329.38800-0.303903.220102.57990HepG2ETF1
RNF8ENSG00000112130.12449.79380634.94550-0.497403.842602.92540HepG2FUBP3
RNF8ENSG00000112130.12883.615101178.85790-0.415902.934902.22090HepG2FXR1
RNF8ENSG00000112130.12601.456801093.72830-0.862708.714407.56870HepG2G3BP1
RNF8ENSG00000112130.12894.821001160.91760-0.375602.523401.67460HepG2G3BP2
RNF8ENSG00000112130.12316.30900548.95490-0.795407.198706.22910HepG2HNRNPA1
RNF8ENSG00000112130.12528.59070936.15460-0.8246013.9718012.19840HepG2HNRNPA2B1
RNF8ENSG00000112130.12712.647401107.11450-0.635506.468405.43140HepG2HNRNPK
RNF8ENSG00000112130.12747.08810927.78660-0.312503.086502.37740HepG2HNRNPL
RNF8ENSG00000112130.12397.50340758.67480-0.932508.297406.23020HepG2HSPD1
RNF8ENSG00000112130.12994.15620763.044400.381603.456402.65420HepG2IGF2BP1
RNF8ENSG00000112130.12585.550801043.14920-0.833103.351302.26720HepG2IGF2BP3
RNF8ENSG00000112130.12663.106101118.18080-0.753806.207804.64720HepG2KHSRP
RNF8ENSG00000112130.12586.22880717.56970-0.291702.561801.57960HepG2KIF1C
RNF8ENSG00000112130.12921.010001206.12540-0.389102.232701.49380HepG2LARP4
RNF8ENSG00000112130.12488.30560659.86660-0.434402.855101.62320HepG2LIN28B
RNF8ENSG00000112130.12718.884501185.91920-0.722206.692805.74490HepG2MATR3
RNF8ENSG00000112130.12409.87420731.16010-0.835009.783108.35270HepG2MSI2
RNF8ENSG00000112130.12728.968101213.89570-0.735705.580004.69450HepG2NCBP2
RNF8ENSG00000112130.12815.322801010.00940-0.308902.161701.48610HepG2NOL12
RNF8ENSG00000112130.12330.65920615.28720-0.895904.719003.27030HepG2NONO
RNF8ENSG00000112130.12826.136001081.24350-0.388202.494501.80570HepG2PABPC4
RNF8ENSG00000112130.12488.09490600.40840-0.298802.083801.34040HepG2PARN
RNF8ENSG00000112130.12887.803001041.78570-0.230701.897101.37840HepG2PCBP1
RNF8ENSG00000112130.12925.15800647.992700.513606.638805.49950HepG2PRPF4
RNF8ENSG00000112130.12327.92830517.14140-0.657204.072103.11530HepG2PRPF8
RNF8ENSG00000112130.12772.562901060.07450-0.456405.570704.84940HepG2PTBP1
RNF8ENSG00000112130.12748.092701023.56810-0.452306.346005.52480HepG2PUM1
RNF8ENSG00000112130.12754.834501041.94170-0.465004.438703.60120HepG2RBM25
RNF8ENSG00000112130.12897.757601098.80070-0.291502.747702.13310HepG2RECQL
RNF8ENSG00000112130.121739.44400834.744401.0591020.1571018.65790HepG2RPLP0
RNF8ENSG00000112130.12402.12690514.24720-0.354801.975801.44830HepG2RPS19
RNF8ENSG00000112130.12841.192501103.64110-0.391804.539103.81010HepG2SF3B4
RNF8ENSG00000112130.12750.90320924.59540-0.300202.747902.04890HepG2SLBP
RNF8ENSG00000112130.12484.32320629.95110-0.379303.599702.88250HepG2SMN1
RNF8ENSG00000112130.12597.158801062.42630-0.831206.046104.88450HepG2SNRNP70
RNF8ENSG00000112130.12736.065701027.37830-0.481102.947201.90880HepG2SRSF3
RNF8ENSG00000112130.12636.18410952.04480-0.581608.007807.01440HepG2SRSF5
RNF8ENSG00000112130.12605.52730937.20550-0.6302010.236009.29070HepG2SRSF9
RNF8ENSG00000112130.121264.880901089.554000.215201.950501.50060HepG2SSB
RNF8ENSG00000112130.12867.246401082.68970-0.320103.363302.69070HepG2SUCLG1
RNF8ENSG00000112130.12490.08690667.21110-0.445102.053201.45770HepG2SUPV3L1
RNF8ENSG00000112130.12690.991701035.47850-0.583608.155507.27520HepG2TAF15
RNF8ENSG00000112130.12713.09090940.19330-0.398902.866002.12990HepG2TARDBP
RNF8ENSG00000112130.12311.23230447.23270-0.523002.742001.75100HepG2TFIP11
RNF8ENSG00000112130.12687.73930951.42380-0.468204.595903.52530HepG2TIA1
RNF8ENSG00000112130.12448.74840594.65450-0.406103.649003.02030HepG2TRIM56
RNF8ENSG00000112130.12707.55470942.04070-0.412903.296602.33650HepG2TUFM
RNF8ENSG00000112130.121106.05090772.791300.517204.328803.55220HepG2U2AF1
RNF8ENSG00000112130.121032.70470855.121000.272102.481001.90750HepG2UTP3
RNF8ENSG00000112130.12636.10820974.11580-0.614807.513306.72620HepG2ZNF622
RNF8ENSG00000112130.12924.17940672.302800.459005.586804.82470K562AGGF1
RNF8ENSG00000112130.12877.87780699.568900.327502.327901.72740K562AKAP8L
RNF8ENSG00000112130.12593.22470866.20900-0.546104.511103.38650K562BOP1
RNF8ENSG00000112130.12537.05200775.25430-0.529604.523702.87740K562CIRBP
RNF8ENSG00000112130.12721.50230921.02280-0.352202.836302.04390K562CPSF6
RNF8ENSG00000112130.121401.077701892.85180-0.434004.501803.24860K562CELF1
RNF8ENSG00000112130.12937.05940752.740000.315902.964002.05270K562DKC1
RNF8ENSG00000112130.12592.05340963.98750-0.7033011.093109.79710K562EIF2S2
RNF8ENSG00000112130.12540.78890794.30740-0.554604.352403.18090K562FTO
RNF8ENSG00000112130.12779.75950569.698800.452704.568103.81760K562FXR1
RNF8ENSG00000112130.12599.15980879.34540-0.553505.127304.05180K562GPKOW
RNF8ENSG00000112130.12688.47450864.54900-0.328502.438501.43260K562HNRNPA1
RNF8ENSG00000112130.12451.74370723.29720-0.679106.865905.96520K562HNRNPC
RNF8ENSG00000112130.12473.26890645.98110-0.448803.225101.98370K562HNRNPF
RNF8ENSG00000112130.12993.451101290.77840-0.377703.009202.18090K562HSPD1
RNF8ENSG00000112130.12939.53540760.209000.305502.203501.44800K562MAGOH
RNF8ENSG00000112130.121126.17920831.669700.437304.403503.20600K562MBNL1
RNF8ENSG00000112130.12612.90250858.34120-0.485904.112403.03020K562METAP2
RNF8ENSG00000112130.121245.478401641.26100-0.398103.034301.85010K562MSI2
RNF8ENSG00000112130.12788.23130954.36570-0.275902.470001.70500K562MTPAP
RNF8ENSG00000112130.12824.93370582.942500.500802.784101.89730K562NAA15
RNF8ENSG00000112130.12480.01720648.53280-0.434102.614101.74010K562PSIP1
RNF8ENSG00000112130.121030.17400693.727700.570305.541704.80440K562PUS1
RNF8ENSG00000112130.121011.20360675.976800.580907.717006.75700K562RBM15
RNF8ENSG00000112130.12345.42640591.80370-0.776707.814906.14710K562RCC2
RNF8ENSG00000112130.12421.81140561.00360-0.411402.415601.47390K562SRFBP1
RNF8ENSG00000112130.12571.84380706.87020-0.305802.040001.34410K562TIA1
RNF8ENSG00000112130.12446.48930623.76770-0.482403.072502.08170K562TIAL1
RNF8ENSG00000112130.12899.039901124.36830-0.322703.654102.83710K562UPF1
RNF8ENSG00000112130.12757.21220962.08890-0.345502.734901.86270K562WDR3
RNF8ENSG00000112130.121111.788601495.01860-0.427304.235403.12900K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RNF8 is not available on ENCORE database.





9 RBPs can affect the splicing of RNF8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERNF8ENSG00000112130.12chr6+3732695837327118373217543732205137328221373283500.377000.000040.00131includedK562SRSF1
SERNF8ENSG00000112130.12chr6+3732695837327118373217543732205137328221373283500.110000.001730.03241includedHepG2U2AF1
SERNF8ENSG00000112130.12chr6+373423953734248537339287373393503734470137344809-0.099000.000050.00164excludedHepG2U2AF1
SERNF8ENSG00000112130.12chr6+373423953734251737339287373393503734470137344809-0.055000.000260.00455excludedHepG2U2AF2
SERNF8ENSG00000112130.12chr6+3732915337329334373281633732835037336259373363140.069000.000000.00001includedK562AQR
SERNF8ENSG00000112130.12chr6+373489253734913037344680373448093735851737362514-0.092000.004660.04386excludedK562AQR
SERNF8ENSG00000112130.12chr6+3732695837327118373217543732205137328221373283500.227000.000490.02217includedK562FXR1
SERNF8ENSG00000112130.12chr6+3732695837327118373217543732205137328221373283500.460000.000000.00011includedHepG2SRSF1
SERNF8ENSG00000112130.12chr6+3732911337329334373282213732835037336259373363140.051000.000140.00638includedHepG2SF3A3
A3SSRNF8ENSG00000112130.12chr6+3733615337336994373362593733699437328221373283500.132000.000100.00877longerK562SF3B4
A3SSRNF8ENSG00000112130.12chr6+3734468037344809373447013734480937342395373424850.069000.000030.00030longerK562AQR
A3SSRNF8ENSG00000112130.12chr6+3733925637339350373392873733935037336259373369940.112000.000000.00000longerK562AQR
MXERNF8ENSG00000112130.12chr6+37339256373393503734239537342485373361533733699437344701373448090.188000.003210.048011includedK562U2AF1
MXERNF8ENSG00000112130.12chr6+37339256373393503734239537342485373362593733699437344701373448090.137000.000100.001211includedK562AQR
MXERNF8ENSG00000112130.12chr6+3733928737339350373447013734480937336259373369943735851737359007-0.155000.000000.000022includedK562AQR
MXERNF8ENSG00000112130.12chr6+3733928737339350373446803734480937336259373369943735851737359007-0.102000.000390.003962includedK562AQR
MXERNF8ENSG00000112130.12chr6+3733928737339350373423953734251737336259373369943734470137344809-0.054000.004850.034992includedK562AQR
MXERNF8ENSG00000112130.12chr6+37339256373393503734239537342485373361533733699437344701373448090.253000.000000.000071includedK562U2AF2
MXERNF8ENSG00000112130.12chr6+37339287373393503734239537342485373362593733699437344701373448090.117000.020040.092811includedHepG2U2AF2
MXERNF8ENSG00000112130.12chr6+37339256373393503734239537342485373361533733699437344701373448090.358000.000000.000001includedHepG2U2AF2
MXERNF8ENSG00000112130.12chr6+37339256373393503734239537342517373361533733699437344701373448090.394000.000250.002581includedHepG2U2AF2
MXERNF8ENSG00000112130.12chr6+37339256373393503734239537342485373361533733699437344701373448090.085000.000070.029871includedK562APOBEC3C
MXERNF8ENSG00000112130.12chr6+3733925637339350373423953734248537336153373369943734470137344809-0.119000.000410.013572includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RNF8 is not avaliable on ENCORE database.