PSMC1

General Information

Gene Name       : PSMC1
Gene ID             : ENSG00000100764.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PSMC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PSMC1ENSG00000100764.13253.31194.69224.00ENCSR000AEF
HepG2PSMC1ENSG00000100764.13144.30202.32173.31ENCSR985KAT
K562PSMC1ENSG00000100764.13164.40154.08159.24ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PSMC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PSMC1 RNA is bound by 8 proteins.  







eCLIP assay for PSMC1 is not avaliable on ENCORE database.





8 proteins are bound to PSMC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr149072966190729673+5'-UTR,CDS,intron-Distal,intron-Proximal4.152333.87582K562ZNF622
chr149072966190729675+5'-UTR,CDS,intron-Distal,intron-Proximal3.781093.69481K562UCHL5
chr149072651790726556+CDS,intron-Distal,intron-Proximal3.306143.34735K562UCHL5
chr149073645090736552+CDS,intron-Proximal5.856687.23238HepG2SF3A3
chr149073049590730615+CDS,intron-Distal,intron-Proximal3.668935.83621K562AQR
chr149073586390735893+CDS,intron-Proximal3.267143.17151K562UCHL5
chr149072651590726556+CDS,intron-Distal,intron-Proximal4.387074.21675K562ZNF622
chr149073667690736747+CDS,intron-Proximal4.772485.60100HepG2PRPF8
chr149072645890726496+CDS,intron-Distal,intron-Proximal3.748656.55026K562ZNF622
chr149073149190731560+CDS,intron-Proximal4.975045.01842HepG2PRPF8
chr149072974890729787+CDS,intron-Distal,intron-Proximal3.337623.27569HepG2BCLAF1
chr149073611790736174+intron-Distal3.938305.18845HepG2U2AF2
chr149073151790731576+intron-Proximal4.735207.01471K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PSMC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PSMC1 is not available on ENCORE database.

  • 86 RBPs can affect the levels of PSMC1.  








The Knockdown/knockout RNA-Seq assay for PSMC1 is not available on ENCORE database.





86 RBPs can affect the gene expression of PSMC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PSMC1ENSG00000100764.92887.088802326.847000.311101.935601.48180HepG2AKAP1
PSMC1ENSG00000100764.91249.129301851.19730-0.567506.885505.98910HepG2BOP1
PSMC1ENSG00000100764.91252.116101699.48740-0.440704.027703.21260HepG2CPSF6
PSMC1ENSG00000100764.92055.557402369.72240-0.205202.685601.95360HepG2DAZAP1
PSMC1ENSG00000100764.91207.415101398.59210-0.212102.272101.51100HepG2DDX19B
PSMC1ENSG00000100764.91622.989902229.04770-0.457803.918103.18520HepG2DDX3X
PSMC1ENSG00000100764.9845.848201107.85770-0.389303.346201.85500HepG2DDX52
PSMC1ENSG00000100764.91004.349701210.04990-0.268802.425301.76140HepG2DNAJC21
PSMC1ENSG00000100764.9960.134401199.40010-0.321004.234903.46070HepG2DNAJC2
PSMC1ENSG00000100764.91130.447601840.74950-0.703408.138007.15910HepG2EIF2S1
PSMC1ENSG00000100764.91412.287102034.36240-0.526504.298003.50540HepG2EIF4A3
PSMC1ENSG00000100764.91424.893102239.60690-0.652408.692107.27940HepG2EIF4G2
PSMC1ENSG00000100764.9734.66480959.02130-0.384503.005901.78090HepG2FAM120A
PSMC1ENSG00000100764.91417.461801903.93170-0.425703.210202.49680HepG2G3BP1
PSMC1ENSG00000100764.91232.725101443.74380-0.228002.230501.34670HepG2HDGF
PSMC1ENSG00000100764.9932.713301221.64290-0.389303.299602.60280HepG2HNRNPA1
PSMC1ENSG00000100764.91783.532302177.89360-0.288203.614102.56890HepG2HNRNPA2B1
PSMC1ENSG00000100764.91017.656301358.86360-0.417203.725602.93060HepG2HNRNPC
PSMC1ENSG00000100764.91328.635501970.70110-0.5688011.6540010.31970HepG2HNRNPF
PSMC1ENSG00000100764.91891.098902158.60380-0.190902.345501.71820HepG2HNRNPL
PSMC1ENSG00000100764.91199.617301838.46590-0.615906.932505.98720HepG2HNRNPLL
PSMC1ENSG00000100764.91285.784401940.58960-0.593809.038907.79850HepG2IGF2BP1
PSMC1ENSG00000100764.91477.498401946.52840-0.397702.333001.42430HepG2KHSRP
PSMC1ENSG00000100764.91181.442401382.36540-0.226602.550701.57000HepG2KIF1C
PSMC1ENSG00000100764.92596.013302064.492800.330402.175601.61270HepG2MATR3
PSMC1ENSG00000100764.91322.762301875.07170-0.503403.215502.16560HepG2MTPAP
PSMC1ENSG00000100764.91625.471802113.17030-0.378602.669802.04650HepG2NCBP2
PSMC1ENSG00000100764.91966.804102349.81750-0.256702.065301.40350HepG2NOL12
PSMC1ENSG00000100764.91478.086001882.13260-0.348602.429801.74930HepG2PABPC4
PSMC1ENSG00000100764.91682.937901995.95640-0.246102.912302.29330HepG2PCBP1
PSMC1ENSG00000100764.91014.618101203.98190-0.246902.087401.43960HepG2PPIL4
PSMC1ENSG00000100764.91220.507101431.00310-0.229502.278701.56900HepG2PRPF4
PSMC1ENSG00000100764.91627.657102030.96460-0.319404.384503.73020HepG2PTBP1
PSMC1ENSG00000100764.91259.024201540.29670-0.290903.722603.03050HepG2PUS1
PSMC1ENSG00000100764.91709.692102199.57560-0.363504.567103.79290HepG2QKI
PSMC1ENSG00000100764.92898.256002129.530800.444508.155307.37510HepG2RBM22
PSMC1ENSG00000100764.91482.884401996.25970-0.428904.950004.07190HepG2RBM25
PSMC1ENSG00000100764.91691.757502260.26500-0.418007.321406.51460HepG2NELFE
PSMC1ENSG00000100764.91504.397502105.13620-0.484709.423308.38740HepG2RECQL
PSMC1ENSG00000100764.91273.431801044.186100.286202.204901.64930HepG2RPS19
PSMC1ENSG00000100764.9857.099601202.11980-0.488007.967006.95960HepG2SAFB2
PSMC1ENSG00000100764.92451.253201780.823300.460903.269502.53570HepG2SF3A3
PSMC1ENSG00000100764.91692.627902114.48850-0.321004.576903.84470HepG2SF3B4
PSMC1ENSG00000100764.91619.616902150.88740-0.409308.348507.22940HepG2SLBP
PSMC1ENSG00000100764.9856.523401643.98360-0.940609.923708.04520HepG2SMNDC1
PSMC1ENSG00000100764.93342.690402405.260600.4747013.1454012.26950HepG2SRFBP1
PSMC1ENSG00000100764.92728.946102207.071400.306104.823304.24290HepG2SRSF1
PSMC1ENSG00000100764.91934.546002214.81060-0.195201.954801.41730HepG2SRSF5
PSMC1ENSG00000100764.91388.332001936.10880-0.479808.492007.38750HepG2SRSF7
PSMC1ENSG00000100764.91675.466501983.81060-0.243702.499301.96280HepG2TAF15
PSMC1ENSG00000100764.9947.676201792.02650-0.9191015.2877013.81120HepG2TARDBP
PSMC1ENSG00000100764.91336.221701822.84240-0.448005.489304.32390HepG2TIA1
PSMC1ENSG00000100764.91001.457301323.38750-0.402105.668804.91420HepG2TRIM56
PSMC1ENSG00000100764.91574.406302191.50420-0.477106.093404.73010HepG2TUFM
PSMC1ENSG00000100764.91997.204801434.238500.477604.758103.94720HepG2U2AF1
PSMC1ENSG00000100764.91746.945602319.70930-0.409103.115802.22820HepG2UBE2L3
PSMC1ENSG00000100764.91088.262401579.31710-0.5373010.749509.53730HepG2UPF1
PSMC1ENSG00000100764.91877.317601524.769900.300003.064302.43970HepG2UTP3
PSMC1ENSG00000100764.93565.695601736.947701.0375063.7681062.05450HepG2ZNF622
PSMC1ENSG00000100764.92987.187002508.490300.251903.409402.79180K562AGGF1
PSMC1ENSG00000100764.92706.472503568.90480-0.399104.325403.62310K562AQR
PSMC1ENSG00000100764.91597.531301973.92750-0.305204.229603.02650K562BCLAF1
PSMC1ENSG00000100764.91251.963702043.48260-0.706809.070207.44180K562BOP1
PSMC1ENSG00000100764.9588.53790864.61880-0.554903.129101.99250K562CCAR1
PSMC1ENSG00000100764.91570.244302172.88500-0.468604.104103.14920K562CPSF6
PSMC1ENSG00000100764.91916.034802252.74390-0.233602.846301.61730K562DDX21
PSMC1ENSG00000100764.91072.174801365.63960-0.349003.025601.93480K562DDX3X
PSMC1ENSG00000100764.93284.774302908.136200.175602.003201.43300K562DDX47
PSMC1ENSG00000100764.92409.664602809.43240-0.221402.387001.71090K562EIF2S2
PSMC1ENSG00000100764.91368.270901841.49460-0.428502.859701.80790K562EIF3D
PSMC1ENSG00000100764.9952.701901426.79510-0.582706.303805.07340K562EIF4A3
PSMC1ENSG00000100764.93187.840104112.94830-0.367605.850404.50680K562EIF4G2
PSMC1ENSG00000100764.91578.972301925.07200-0.285902.554401.34260K562EXOSC5
PSMC1ENSG00000100764.91468.398501873.71210-0.351702.621601.73460K562FTO
PSMC1ENSG00000100764.92446.110401483.813600.7211018.6355017.17450K562FXR1
PSMC1ENSG00000100764.91614.141802074.63170-0.362103.142402.29860K562GPKOW
PSMC1ENSG00000100764.91007.599101468.54700-0.543505.545504.72940K562HNRNPC
PSMC1ENSG00000100764.92643.410802043.395500.371303.003601.71570K562HNRNPK
PSMC1ENSG00000100764.92879.704401977.640700.542005.408604.05090K562HNRNPM
PSMC1ENSG00000100764.94488.544103259.606600.461405.554704.44440K562HSPD1
PSMC1ENSG00000100764.91672.639002150.20640-0.362303.626402.65640K562MAGOH
PSMC1ENSG00000100764.91459.817402025.04620-0.472204.897403.71190K562METAP2
PSMC1ENSG00000100764.92138.340502449.14740-0.195802.904202.14250K562NSUN2
PSMC1ENSG00000100764.92671.493401673.520000.674709.540808.14360K562PRPF8
PSMC1ENSG00000100764.93674.744404676.86940-0.347905.387804.02840K562PUM2
PSMC1ENSG00000100764.93291.829502588.768300.346502.906402.35230K562PUS1
PSMC1ENSG00000100764.92090.613602475.98770-0.244103.644402.58690K562SRPK2
PSMC1ENSG00000100764.92489.067502047.980100.281302.608601.91970K562SRSF1
PSMC1ENSG00000100764.91316.354901640.63530-0.317702.717801.68070K562SRSF4
PSMC1ENSG00000100764.91690.770902010.53580-0.249902.965401.75170K562SRSF7
PSMC1ENSG00000100764.91193.095001620.52780-0.441803.277802.16570K562SUPV3L1
PSMC1ENSG00000100764.92580.092101883.895200.453606.523105.25350K562SYNCRIP
PSMC1ENSG00000100764.91632.589502072.68340-0.344302.755302.04910K562TARDBP
PSMC1ENSG00000100764.92293.152901719.962700.414903.219102.02250K562U2AF1
PSMC1ENSG00000100764.92363.267801776.108300.412005.421804.30170K562U2AF2
PSMC1ENSG00000100764.92028.243202596.88500-0.356606.336505.30150K562UPF1
PSMC1ENSG00000100764.91867.378402222.06910-0.250902.087401.32880K562WDR3
PSMC1ENSG00000100764.92715.375702310.717200.232703.449102.51180K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PSMC1 is not available on ENCORE database.





4 RBPs can affect the splicing of PSMC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPSMC1ENSG00000100764.9chr14+907299729073019190729661907297869073038490730513-0.314000.000030.00245excludedK562SF3B1
SEPSMC1ENSG00000100764.9chr14+907300059073019190729661907297869073038490730513-0.067000.000030.00104excludedK562HNRNPC
A3SSPSMC1ENSG00000100764.9chr14+9073138790731510907314139073151090730384907305130.051000.000000.00005longerK562AQR
RIPSMC1ENSG00000100764.9chr14+9073574090736696907357409073589290736541907366960.075000.000000.00000includedK562AQR
MXEPSMC1ENSG00000100764.9chr14+9073000590730191907303849073051390729661907297869073141390731510-0.099000.000810.073702includedK562NPM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PSMC1 is not avaliable on ENCORE database.