PDCL

General Information

Gene Name       : PDCL
Gene ID             : ENSG00000136940.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PDCL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PDCLENSG00000136940.137.748.878.30ENCSR000AEF
HepG2PDCLENSG00000136940.1313.1414.9014.02ENCSR985KAT
K562PDCLENSG00000136940.138.438.578.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PDCL is not avaliable on ENCORE database.



Proteins bound to RNA
  • PDCL RNA is bound by 8 proteins.  







eCLIP assay for PDCL is not avaliable on ENCORE database.





8 proteins are bound to PDCL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9125582246125582323-3'-UTR,intron-Distal3.378363.59190K562TIA1
chr9125581743125581896-3'-UTR,intron-Distal3.117155.54889K562UPF1
chr9125581819125581919-3'-UTR,intron-Distal3.153475.67011K562DDX6
chr9125581844125581891-3'-UTR,intron-Distal3.446684.09267K562FAM120A
chr9125582809125582906-3'-UTR,CDS,intron-Distal,intron-Proximal3.779423.65778K562GRWD1
chr9125588912125589040-CDS,intron-Distal,intron-Proximal3.937065.08388K562UCHL5
chr9125588934125589066-CDS,intron-Distal,intron-Proximal4.402244.23295HepG2GRWD1
chr9125585295125585394-CDS,intron-Distal3.998275.37538K562ZNF622
chr9125585293125585442-CDS,intron-Distal,intron-Proximal3.366873.79741HepG2GRWD1
chr9125579837125579907-intron-Distal3.515375.56056K562AKAP1
chr9125579841125579906-intron-Distal4.765665.60103K562UPF1
chr9125579399125579481-intron-Distal5.060865.00858K562AKAP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PDCL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PDCL is not available on ENCORE database.

  • 76 RBPs can affect the levels of PDCL.  








The Knockdown/knockout RNA-Seq assay for PDCL is not available on ENCORE database.





76 RBPs can affect the gene expression of PDCL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PDCLENSG00000136940.9340.99630438.17930-0.361802.466401.88680HepG2ACO1
PDCLENSG00000136940.9482.40230648.31360-0.426503.838403.05480HepG2AUH
PDCLENSG00000136940.9300.03650465.96210-0.635103.272602.25520HepG2BCCIP
PDCLENSG00000136940.9290.07850404.91220-0.481202.137401.34350HepG2BCLAF1
PDCLENSG00000136940.9183.75620398.44210-1.1166010.343209.28180HepG2BOP1
PDCLENSG00000136940.9249.75530438.11740-0.810809.435008.35080HepG2CKAP4
PDCLENSG00000136940.9314.44440423.29720-0.428902.854501.82020HepG2YBX3
PDCLENSG00000136940.9148.26630287.86100-0.957206.293604.76980HepG2CSTF2
PDCLENSG00000136940.9465.58010603.91100-0.375303.023002.35620HepG2CELF1
PDCLENSG00000136940.9209.71510405.26840-0.9504012.2972010.79800HepG2DDX19B
PDCLENSG00000136940.9317.53200423.89370-0.416802.491201.39590HepG2DDX1
PDCLENSG00000136940.9261.45500428.68780-0.713403.245001.85870HepG2DDX27
PDCLENSG00000136940.9215.81000347.10520-0.685603.648202.04660HepG2DDX28
PDCLENSG00000136940.9234.07820458.12320-0.968706.765405.61890HepG2DDX55
PDCLENSG00000136940.9283.45750400.89560-0.500103.008601.99050HepG2DHX30
PDCLENSG00000136940.9305.75500415.65450-0.443002.994302.26730HepG2DNAJC21
PDCLENSG00000136940.9181.10600411.97200-1.1857017.0554015.56950HepG2DNAJC2
PDCLENSG00000136940.9299.44050447.45680-0.579503.407502.75360HepG2EIF2S1
PDCLENSG00000136940.9224.80270316.43200-0.493202.167501.35790HepG2EIF3D
PDCLENSG00000136940.9421.64940640.63440-0.603506.955705.73920HepG2EIF4G1
PDCLENSG00000136940.9428.21590613.69700-0.519203.854802.90450HepG2EIF4G2
PDCLENSG00000136940.9585.50010744.33470-0.346302.701302.10610HepG2ETF1
PDCLENSG00000136940.9646.70900498.940100.374202.017401.42320HepG2FXR1
PDCLENSG00000136940.9242.56250414.63500-0.773504.962204.12020HepG2GPKOW
PDCLENSG00000136940.9168.86570310.50520-0.878703.661402.37840HepG2GRSF1
PDCLENSG00000136940.9485.34730596.80240-0.298202.152201.31690HepG2HNRNPA2B1
PDCLENSG00000136940.9315.96380466.76390-0.562903.609602.82530HepG2HNRNPC
PDCLENSG00000136940.9294.06550395.69500-0.428301.992001.44920HepG2HNRNPLL
PDCLENSG00000136940.9283.00460463.67820-0.712307.561706.59830HepG2HNRNPU
PDCLENSG00000136940.9315.44990405.81650-0.363402.027401.40130HepG2IGF2BP1
PDCLENSG00000136940.9293.69820473.63270-0.689407.993606.81540HepG2ILF2
PDCLENSG00000136940.9270.43690400.57160-0.566804.952603.59310HepG2KIF1C
PDCLENSG00000136940.9389.02540656.92560-0.755905.600904.40600HepG2LARP4
PDCLENSG00000136940.9320.34820457.48690-0.514102.905202.16640HepG2PABPC4
PDCLENSG00000136940.9287.37350413.56460-0.525203.955703.09090HepG2PPIL4
PDCLENSG00000136940.9458.45560652.50600-0.509206.212605.39790HepG2PUM1
PDCLENSG00000136940.9485.31370652.04270-0.426003.411002.66820HepG2PUM2
PDCLENSG00000136940.9237.03850408.29200-0.784503.971902.69900HepG2RCC2
PDCLENSG00000136940.9268.84130443.97970-0.723705.753604.82020HepG2RPLP0
PDCLENSG00000136940.9189.27930307.89110-0.701904.373503.61850HepG2RPS19
PDCLENSG00000136940.9187.93290349.67580-0.895805.213604.16640HepG2RRP9
PDCLENSG00000136940.9295.09510412.92830-0.484703.709302.98260HepG2SAFB2
PDCLENSG00000136940.9370.50220481.54820-0.378202.968502.30560HepG2SMN1
PDCLENSG00000136940.9569.06960702.67820-0.304302.282101.81300HepG2SRFBP1
PDCLENSG00000136940.9730.08780534.021500.451104.133603.58430HepG2SRSF1
PDCLENSG00000136940.9301.69000404.89850-0.424502.934302.22090HepG2SRSF7
PDCLENSG00000136940.9387.66270610.10140-0.654207.762206.98810HepG2SSB
PDCLENSG00000136940.9535.06310690.23170-0.367403.539502.85240HepG2SUCLG1
PDCLENSG00000136940.9306.65330456.07720-0.572702.726902.05350HepG2SUPV3L1
PDCLENSG00000136940.9200.54500385.71420-0.943607.453106.33900HepG2TARDBP
PDCLENSG00000136940.9204.55600305.70640-0.579702.608801.63790HepG2TFIP11
PDCLENSG00000136940.9307.89870441.06030-0.518503.554002.61080HepG2TIA1
PDCLENSG00000136940.9278.72230450.56510-0.692906.024605.33960HepG2TIAL1
PDCLENSG00000136940.9302.28640454.57670-0.588605.407304.67020HepG2TRIM56
PDCLENSG00000136940.9432.93190635.59400-0.554003.251402.34450HepG2UBE2L3
PDCLENSG00000136940.9158.84990269.43440-0.762303.689802.81390HepG2UCHL5
PDCLENSG00000136940.9309.44730448.95730-0.536902.633501.92650HepG2XRN2
PDCLENSG00000136940.9355.28640457.75690-0.365602.692502.15120HepG2ZNF622
PDCLENSG00000136940.9901.07720668.229300.431203.632902.88100K562AKAP8L
PDCLENSG00000136940.9291.22000397.09830-0.447402.206501.43340K562BOP1
PDCLENSG00000136940.9529.15370732.15450-0.468503.592402.12430K562CIRBP
PDCLENSG00000136940.9347.87940530.14730-0.607803.983302.20160K562CKAP4
PDCLENSG00000136940.9532.68790753.45890-0.500203.792302.06620K562DDX19B
PDCLENSG00000136940.9475.06500710.56180-0.580806.821505.86280K562DDX47
PDCLENSG00000136940.9151.00200252.13020-0.739602.741401.74360K562EIF3A
PDCLENSG00000136940.9331.42550479.86150-0.533902.936401.86770K562EIF3D
PDCLENSG00000136940.9308.59220439.25630-0.509403.797902.87510K562EIF3G
PDCLENSG00000136940.9702.23680917.63870-0.386003.857902.75140K562EIF4G2
PDCLENSG00000136940.9456.19790583.39420-0.354802.353601.78700K562FXR1
PDCLENSG00000136940.9359.61460702.42720-0.9659011.264209.71220K562GRSF1
PDCLENSG00000136940.9267.50010469.35500-0.811107.052506.14170K562HNRNPC
PDCLENSG00000136940.9269.31210419.16950-0.638304.488902.99340K562HNRNPF
PDCLENSG00000136940.9530.60330716.50610-0.433303.522102.46670K562MATR3
PDCLENSG00000136940.9975.22030794.412000.295702.165501.37730K562MBNL1
PDCLENSG00000136940.9262.95610393.52340-0.581603.687502.66710K562METAP2
PDCLENSG00000136940.9282.92160541.78770-0.937309.155807.77110K562MTPAP
PDCLENSG00000136940.9813.71060546.870000.573202.167401.31220K562PABPN1
PDCLENSG00000136940.9592.31560436.155000.441402.587601.86260K562PRPF8
PDCLENSG00000136940.9549.02440697.51120-0.345302.478701.84450K562PTBP1
PDCLENSG00000136940.9806.223401043.41950-0.372103.736802.61900K562PUM2
PDCLENSG00000136940.91194.26370662.649200.8497011.4474010.39100K562PUS1
PDCLENSG00000136940.9863.39340645.694000.419104.114203.40770K562RBM15
PDCLENSG00000136940.9219.04010384.00470-0.809906.444004.93090K562RCC2
PDCLENSG00000136940.9429.13620703.90570-0.713906.825405.02040K562NELFE
PDCLENSG00000136940.9260.72080417.15020-0.678104.025302.78840K562RPS3
PDCLENSG00000136940.9452.91280683.77620-0.594305.485904.49670K562SRSF1
PDCLENSG00000136940.9293.82230402.73140-0.454902.426101.44960K562SRSF4
PDCLENSG00000136940.9492.41830667.56360-0.439003.403002.48150K562TIA1
PDCLENSG00000136940.9292.33390404.76780-0.469502.399001.53190K562TIAL1
PDCLENSG00000136940.9301.33550455.12270-0.594903.915102.37890K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PDCL is not available on ENCORE database.





4 RBPs can affect the splicing of PDCL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPDCLENSG00000136940.9chr9-1255852941255855401255852941255854761255888941255890710.096000.000000.00000longerK562AQR
MXEPDCLENSG00000136940.9chr9-1255852941255854761255888941255890711255806221255829151255907491255909100.126000.003530.037401includedHepG2SFPQ
MXEPDCLENSG00000136940.9chr9-1255852941255853611255888941255890711255806221255829151255907491255909100.120000.007620.065511includedHepG2SFPQ
MXEPDCLENSG00000136940.9chr9-1255852941255854761255888941255890711255806221255829151255907491255909100.151000.000530.004751includedHepG2U2AF2
MXEPDCLENSG00000136940.9chr9-1255852941255853611255888941255890711255806221255829151255907491255909100.149000.000980.008021includedHepG2U2AF2
MXEPDCLENSG00000136940.9chr9-125585294125585476125588894125589071125580622125582915125590749125590910-0.213000.000070.005012includedK562DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PDCL is not avaliable on ENCORE database.