PAXIP1

General Information

Gene Name       : PAXIP1
Gene ID             : ENSG00000157212.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PAXIP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PAXIP1ENSG00000157212.1819.1318.4918.81ENCSR000AEF
HepG2PAXIP1ENSG00000157212.1812.0615.3813.72ENCSR985KAT
K562PAXIP1ENSG00000157212.1821.7724.2723.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PAXIP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PAXIP1 RNA is bound by 24 proteins.  







eCLIP assay for PAXIP1 is not avaliable on ENCORE database.





24 proteins are bound to PAXIP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7154760386154760534-3'-UTR,CDS,intron-Distal3.103916.35635K562UCHL5
chr7154739559154739632-3'-UTR,CDS,intron-Distal,intron-Proximal3.837875.28701K562PRPF8
chr7154767770154767867-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.407407.55782K562ZNF622
chr7154767784154767862-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.957556.77066K562UCHL5
chr7154735780154735885-3'-UTR,CDS,intron-Distal4.743364.65563K562AQR
chr7154759536154759612-3'-UTR,CDS,intron-Distal3.409843.12941K562UCHL5
chr7154760394154760514-3'-UTR,CDS,intron-Distal3.716943.57062K562IGF2BP1
chr7154760516154760573-3'-UTR,CDS,intron-Distal5.074988.63033K562RBM15
chr7154735505154735578-3'-UTR,intron-Distal6.2403115.61756K562PUM2
chr7154735596154735643-3'-UTR,intron-Distal5.901275.76336K562PUM2
chr7154760668154760713-3'-UTR,CDS,intron-Distal,intron-Proximal3.849623.15006K562RBM15
chr7154760321154760516-3'-UTR,CDS,intron-Distal3.6856810.46214K562ZNF622
chr7154760162154760238-3'-UTR,CDS,intron-Distal3.190923.55138K562ZNF622
chr7154760506154760595-3'-UTR,CDS,intron-Distal4.018323.02541K562IGF2BP2
chr7154751552154751612-3'-UTR,CDS,intron-Distal,intron-Proximal4.559685.17894K562PRPF8
chr7154753253154753358-3'-UTR,CDS,intron-Distal5.440698.09274K562LIN28B
chr7154760271154760369-3'-UTR,CDS,intron-Distal4.686275.51000K562MTPAP
chr7154760440154760516-3'-UTR,CDS,intron-Distal4.1361111.20412K562RBM15
chr7154760389154760440-3'-UTR,CDS,intron-Distal4.217508.85903K562RBM15
chr7154739558154739648-3'-UTR,CDS,intron-Distal,intron-Proximal3.844675.34978HepG2PRPF8
chr7154738139154738230-3'-UTR,CDS,intron-Distal,intron-Proximal4.495624.58968K562PRPF8
chr7154767743154767850-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.042326.22576HepG2BCLAF1
chr7154794616154794699-5'-UTR,CDS,intron-Distal,intron-Proximal4.289076.39945K562GTF2F1
chr7154794632154794691-5'-UTR,CDS,intron-Distal,intron-Proximal4.052248.41080HepG2PRPF4
chr7154794638154794688-5'-UTR,CDS,intron-Distal,intron-Proximal4.002946.00287K562GEMIN5
chr7154767624154767722-5'-UTR,CDS,intron-Distal3.781406.77066K562UCHL5
chr7154767862154767939-5'-UTR,CDS,intron-Distal5.473429.91399K562UCHL5
chr7154767488154767578-5'-UTR,CDS,intron-Distal3.714553.73423K562UCHL5
chr7154794640154794686-5'-UTR,intron-Distal,intron-Proximal4.875485.60060K562NCBP2
chr7154794626154794690-5'-UTR,CDS,intron-Distal,intron-Proximal3.526835.02933K562CSTF2T
chr7154794631154794692-5'-UTR,CDS,intron-Distal,intron-Proximal5.391509.90275HepG2GTF2F1
chr7154767867154767941-5'-UTR,CDS,intron-Distal3.855217.95479K562ZNF622
chr7154794632154794688-5'-UTR,CDS,intron-Distal,intron-Proximal4.137723.98935HepG2NCBP2
chr7154794640154794687-5'-UTR,intron-Distal,intron-Proximal4.674864.59452HepG2PCBP2
chr7154782674154782752-CDS,intron-Distal,intron-Proximal3.015954.91549K562PRPF8
chr7154782604154782734-CDS,intron-Distal,intron-Proximal3.233066.18396K562KHSRP
chr7154782714154782744-CDS,intron-Distal,intron-Proximal4.500814.89018K562EFTUD2
chr7154768094154768162-intron-Distal,intron-Proximal4.514576.28383K562KHSRP
chr7154789263154789403-intron-Distal4.230954.07352K562KHSRP
chr7154782699154782711-intron-Distal,intron-Proximal4.351834.36481K562EFTUD2
chr7154760040154760087-intron-Distal,intron-Proximal4.743364.65563K562AQR
chr7154782336154782460-intron-Distal3.834453.39089K562KHDRBS1
chr7154762390154762475-intron-Distal4.651323.83114K562DGCR8
chr7154791407154791490-intron-Distal4.257803.55640HepG2QKI
chr7154735903154735960-intron-Distal3.994893.60944K562TARDBP
chr7154780732154780790-intron-Distal3.754885.98773K562KHSRP
chr7154735976154736062-intron-Distal4.122444.13641K562TARDBP
chr7154780642154780732-intron-Distal4.3173210.50718K562KHSRP
chr7154793598154793720-intron-Distal4.058413.62366HepG2HNRNPM
chr7154778685154778745-intron-Distal4.219384.12480HepG2HNRNPM
chr7154780845154780936-intron-Distal5.170308.49499K562KHSRP
chr7154773255154773325-intron-Distal4.353694.79477K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PAXIP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PAXIP1 is not available on ENCORE database.

  • 62 RBPs can affect the levels of PAXIP1.  








The Knockdown/knockout RNA-Seq assay for PAXIP1 is not available on ENCORE database.





62 RBPs can affect the gene expression of PAXIP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PAXIP1ENSG00000157212.14156.52120467.54890-1.5788015.7651014.60170HepG2AKAP1
PAXIP1ENSG00000157212.14395.49590544.89870-0.462302.510301.51650HepG2AKAP8
PAXIP1ENSG00000157212.14525.56090741.45710-0.496505.599204.68210HepG2AUH
PAXIP1ENSG00000157212.14554.04540912.17370-0.719307.970307.01790HepG2BOP1
PAXIP1ENSG00000157212.14483.74620687.30800-0.506704.312303.37440HepG2CALR
PAXIP1ENSG00000157212.14622.10090837.41490-0.428802.966802.25760HepG2CPSF6
PAXIP1ENSG00000157212.14517.40890668.68130-0.370002.923002.26520HepG2CELF1
PAXIP1ENSG00000157212.14273.68200441.56160-0.690104.298903.35790HepG2DDX55
PAXIP1ENSG00000157212.14235.79480384.69720-0.706203.953903.22580HepG2DDX6
PAXIP1ENSG00000157212.14304.24470446.28740-0.552704.430703.55630HepG2DNAJC21
PAXIP1ENSG00000157212.14556.52510408.787300.445002.410601.81250HepG2EIF4A3
PAXIP1ENSG00000157212.14553.23560709.33000-0.358602.988402.12360HepG2EIF4G1
PAXIP1ENSG00000157212.14452.91530679.48740-0.585204.689603.64730HepG2EIF4G2
PAXIP1ENSG00000157212.14587.03950412.362600.509403.199002.45630HepG2FXR1
PAXIP1ENSG00000157212.14644.40090406.090000.666105.378504.12500HepG2G3BP2
PAXIP1ENSG00000157212.14484.30600326.121600.570403.648102.60770HepG2GEMIN5
PAXIP1ENSG00000157212.14588.23220949.24700-0.690406.071005.14810HepG2GPKOW
PAXIP1ENSG00000157212.14364.78780467.71170-0.358602.457901.53060HepG2HDGF
PAXIP1ENSG00000157212.14504.26930660.76350-0.389903.127102.14110HepG2HNRNPA2B1
PAXIP1ENSG00000157212.14614.70540905.88640-0.559404.634403.84120HepG2HNRNPLL
PAXIP1ENSG00000157212.14379.28800497.83960-0.392403.086502.44880HepG2HNRNPU
PAXIP1ENSG00000157212.14713.47830412.506200.790407.190406.14810HepG2MAGOH
PAXIP1ENSG00000157212.14573.31510424.612000.433102.354201.76740HepG2NCBP2
PAXIP1ENSG00000157212.14514.42300410.827000.324302.199001.64720HepG2PCBP1
PAXIP1ENSG00000157212.14420.94450302.902100.474703.125101.81550HepG2PKM
PAXIP1ENSG00000157212.14375.61550680.55720-0.857509.721908.69790HepG2PUF60
PAXIP1ENSG00000157212.14618.98480844.29580-0.447804.127703.10520HepG2RBM15
PAXIP1ENSG00000157212.14553.47980711.52120-0.362402.810002.28900HepG2RBM22
PAXIP1ENSG00000157212.14634.10930473.332400.421802.646601.67610HepG2RBM27
PAXIP1ENSG00000157212.14605.59960465.231500.380302.842602.29570HepG2NELFE
PAXIP1ENSG00000157212.14557.42220433.311900.363302.613502.01220HepG2RECQL
PAXIP1ENSG00000157212.14465.27470760.72370-0.709306.929405.92090HepG2RPLP0
PAXIP1ENSG00000157212.14349.27950506.38720-0.535902.526801.62070HepG2RPS10
PAXIP1ENSG00000157212.141206.15600813.935100.567303.576102.80650HepG2SF3A3
PAXIP1ENSG00000157212.14554.77660435.219100.350102.428601.86970HepG2SF3B4
PAXIP1ENSG00000157212.14488.01660803.63780-0.7196010.8798010.06400HepG2SRFBP1
PAXIP1ENSG00000157212.14690.46740454.280300.603907.017206.34690HepG2SRSF1
PAXIP1ENSG00000157212.14549.33310693.87650-0.337002.542401.87260HepG2SRSF7
PAXIP1ENSG00000157212.14277.48600439.54250-0.663604.114903.31370HepG2SUPV3L1
PAXIP1ENSG00000157212.14605.73490883.03310-0.543804.771403.85400HepG2TARDBP
PAXIP1ENSG00000157212.14380.59130483.80310-0.346201.991701.55270HepG2TIAL1
PAXIP1ENSG00000157212.14376.59580488.06470-0.374102.777602.21280HepG2TRIM56
PAXIP1ENSG00000157212.141070.11000683.121000.647406.780605.80840HepG2U2AF1
PAXIP1ENSG00000157212.14549.98870721.83630-0.392303.763902.96890HepG2UPF1
PAXIP1ENSG00000157212.14947.10130696.904100.442505.105404.33340HepG2UTP3
PAXIP1ENSG00000157212.14483.54200682.34470-0.496905.713404.80230HepG2ZC3H8
PAXIP1ENSG00000157212.14640.40710793.88130-0.309903.061302.49410HepG2ZNF622
PAXIP1ENSG00000157212.14423.21340702.07000-0.7302010.362107.55610K562AKAP1
PAXIP1ENSG00000157212.141009.827501286.91430-0.349802.934302.26100K562AKAP8L
PAXIP1ENSG00000157212.141134.120001350.23050-0.251602.357901.52170K562ATP5C1
PAXIP1ENSG00000157212.141201.142101667.56970-0.473304.418203.30760K562BOP1
PAXIP1ENSG00000157212.141326.675401773.09500-0.418504.878103.84180K562CPSF6
PAXIP1ENSG00000157212.141198.181901459.09460-0.284202.913101.66780K562DDX21
PAXIP1ENSG00000157212.141163.53680743.128200.646707.576006.22020K562EIF4A3
PAXIP1ENSG00000157212.141206.930301529.14740-0.341402.454601.59500K562FTO
PAXIP1ENSG00000157212.141294.90850772.817100.7446014.0355012.77690K562FXR1
PAXIP1ENSG00000157212.141159.274401692.86120-0.546206.552505.33430K562GPKOW
PAXIP1ENSG00000157212.141527.072502029.69530-0.410504.325603.38440K562GRSF1
PAXIP1ENSG00000157212.141626.193902369.60360-0.543106.573305.36070K562HSPD1
PAXIP1ENSG00000157212.141319.78290975.477700.436002.557301.74890K562MAGOH
PAXIP1ENSG00000157212.141428.378601659.59760-0.216502.851202.09490K562NSUN2
PAXIP1ENSG00000157212.141536.059001983.96040-0.369103.229702.33150K562PPIG
PAXIP1ENSG00000157212.141186.39520947.728500.323902.754602.09160K562PTBP1
PAXIP1ENSG00000157212.141498.433701110.029000.432804.396703.02040K562SAFB
PAXIP1ENSG00000157212.141035.12270787.935800.393603.821102.81130K562SF3B4
PAXIP1ENSG00000157212.141874.070101206.860600.634802.599501.42480K562SNRNP200
PAXIP1ENSG00000157212.141928.871201677.678400.201202.328501.46130K562SRPK2
PAXIP1ENSG00000157212.141812.236501249.531200.536304.012603.01820K562SYNCRIP
PAXIP1ENSG00000157212.141010.79270758.588400.414002.352201.61190K562U2AF2
PAXIP1ENSG00000157212.141219.902501505.72820-0.303702.569001.72290K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PAXIP1 is not available on ENCORE database.





14 RBPs can affect the splicing of PAXIP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.169000.000000.00015excludedK562SF3B4
SEPAXIP1ENSG00000157212.14chr7-1547777261547778891547749281547750421547827151547827790.219000.000000.00080includedK562WDR3
SEPAXIP1ENSG00000157212.14chr7-1547777651547778891547749281547750421547827151547827790.227000.000020.00124includedK562AKAP8L
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.055000.000280.01136excludedK562AKAP8L
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.083000.000000.00004excludedK562AQR
SEPAXIP1ENSG00000157212.14chr7-154777765154777889154774928154775042154782715154782779-0.191000.000590.02558excludedK562FXR1
SEPAXIP1ENSG00000157212.14chr7-1547777651547778891547749281547750421547827151547827790.279000.000000.00022includedK562SUPV3L1
SEPAXIP1ENSG00000157212.14chr7-1547777651547778891547749281547750421547827151547827790.117000.007090.08088includedK562PUS1
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.071000.000010.00042excludedK562PUS1
SEPAXIP1ENSG00000157212.14chr7-1547777261547778891547749281547750421547827151547827790.268000.000000.00010includedK562UTP18
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.057000.000090.00523excludedK562UTP18
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.103000.000940.01890excludedK562U2AF2
SEPAXIP1ENSG00000157212.14chr7-1547777261547778891547749281547750421547827151547827790.167000.000630.02635includedK562HNRNPU
SEPAXIP1ENSG00000157212.14chr7-154748933154749004154747238154747341154751599154751643-0.079000.000000.00028excludedK562RBM15
SEPAXIP1ENSG00000157212.14chr7-1547777651547778891547749281547750421547827151547827790.142000.004620.08758includedK562AGGF1
SEPAXIP1ENSG00000157212.14chr7-154777765154777889154774928154775042154782715154782779-0.245000.000000.00335excludedHepG2EIF3D
SEPAXIP1ENSG00000157212.14chr7-1547777651547778891547749281547750421547827151547827790.176000.000440.08912includedK562SERBP1
A3SSPAXIP1ENSG00000157212.14chr7-1547827151547828671547827151547827791547854351547854790.149000.000110.00097longerK562AQR
A3SSPAXIP1ENSG00000157212.14chr7-1547749281547751551547749281547750421547777261547778890.124000.019340.09267longerK562AQR
A3SSPAXIP1ENSG00000157212.14chr7-1547489331547490411547489331547490041547515991547517800.121000.000000.00001longerK562AQR
A3SSPAXIP1ENSG00000157212.14chr7-1547396121547398351547396121547397131547459641547461330.155000.000000.00000longerK562AQR
A3SSPAXIP1ENSG00000157212.14chr7-154739612154739835154739612154739737154745964154746133-0.664000.014850.07416shorterK562AQR
MXEPAXIP1ENSG00000157212.14chr7-1547472381547473411547515991547516431547459641547461331547526021547527870.238000.004080.048001includedK562U2AF2
MXEPAXIP1ENSG00000157212.14chr7-154767405154768041154774928154775042154760112154760836154782715154782779-0.306000.000010.000822includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PAXIP1 is not avaliable on ENCORE database.