LTBR

General Information

Gene Name       : LTBR
Gene ID             : ENSG00000111321.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LTBR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LTBRENSG00000111321.100.000.000.00ENCSR000AEF
HepG2LTBRENSG00000111321.1040.8323.7532.29ENCSR985KAT
K562LTBRENSG00000111321.1044.6546.4345.54ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LTBR is not avaliable on ENCORE database.



Proteins bound to RNA
  • LTBR RNA is bound by 21 proteins.  







eCLIP assay for LTBR is not avaliable on ENCORE database.





21 proteins are bound to LTBR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1265006506500722+3'-UTR3.648104.92393K562PUM2
chr1265001646500233+3'-UTR4.134145.15345K562UPF1
chr1265001306500223+3'-UTR3.252714.09351K562IGF2BP2
chr1265002486500364+3'-UTR3.112113.33646HepG2AKAP1
chr1264976676497695+3'-UTR,CDS,intron-Distal,intron-Proximal3.926426.80869K562AQR
chr1265002526500353+3'-UTR5.062017.94456HepG2UPF1
chr1264976566497726+3'-UTR,CDS,intron-Distal,intron-Proximal4.3963612.93660HepG2PRPF8
chr1264976696497713+3'-UTR,CDS,intron-Distal,intron-Proximal3.917245.56912HepG2AQR
chr1265005666500608+3'-UTR3.431205.35486K562UPF1
chr1264979056498041+3'-UTR,CDS,intron-Proximal4.0636313.80228HepG2AQR
chr1265005556500618+3'-UTR4.6915310.56484HepG2UPF1
chr1264970676497129+3'-UTR,intron-Distal,intron-Proximal4.319245.13071HepG2HNRNPK
chr1265006086500705+3'-UTR5.6787723.35679K562UPF1
chr1265006226500702+3'-UTR4.286145.91583K562DDX6
chr1265006186500695+3'-UTR4.010246.47490HepG2UPF1
chr1265001576500248+3'-UTR4.848137.20635HepG2AKAP1
chr1265001206500244+3'-UTR5.7694015.41547HepG2UPF1
chr1264935346493588+5'-UTR,CDS,intron-Distal5.0888529.92548HepG2DDX3X
chr1264943906494487+5'-UTR,CDS,intron-Proximal3.476249.66295HepG2GRWD1
chr1264942226494315+5'-UTR,CDS,intron-Proximal3.9131614.34728K562YBX3
chr1264938006493851+5'-UTR,CDS,intron-Proximal3.6461110.69967HepG2PPIG
chr1264933976493468+5'-UTR,intron-Distal5.6321147.07839HepG2DDX3X
chr1264934686493529+5'-UTR,CDS,intron-Distal4.5438427.06936HepG2DDX3X
chr1264942706494314+5'-UTR,CDS,intron-Proximal3.060364.34383HepG2GRWD1
chr1264933996493490+5'-UTR,intron-Distal3.664073.19539K562YBX3
chr1264934556493590+5'-UTR,CDS,intron-Distal4.475715.87587K562GEMIN5
chr1264933326493391+5'-UTR,intron-Distal3.976634.66602K562DDX3X
chr1264943916494464+5'-UTR,CDS,intron-Proximal3.1694016.68325HepG2PPIG
chr1264933466493397+5'-UTR,intron-Distal4.6784532.98255HepG2DDX3X
chr1264998826499956+CDS3.854843.59284HepG2LSM11
chr1264994346499494+CDS3.728283.12746HepG2GRWD1
chr1264951916495271+CDS,intron-Distal,intron-Proximal3.277696.05940K562AQR
chr1264992656499356+CDS,intron-Proximal4.240684.49756K562BUD13
chr1264951876495235+CDS,intron-Distal,intron-Proximal5.200715.40008K562SF3B4
chr1264945426494578+CDS,intron-Proximal3.4296327.39015HepG2PRPF8
chr1264951646495236+CDS,intron-Distal,intron-Proximal3.464488.43738HepG2SF3B4
chr1264956106495616+CDS,intron-Proximal5.738049.23760K562AQR
chr1264945436494573+CDS,intron-Proximal4.014318.67867K562AQR
chr1264992936499434+CDS3.941847.27605HepG2GRWD1
chr1264944646494504+CDS4.210566.39364HepG2PPIG
chr1264945446494582+CDS,intron-Proximal3.390016.15340HepG2AQR
chr1264951886495276+CDS,intron-Distal,intron-Proximal4.241279.52373HepG2AQR
chr1264976956497714+intron-Distal,intron-Proximal5.234826.75320K562AQR
chr1264958086495853+intron-Distal4.482934.24565HepG2HNRNPL
chr1264971726497278+intron-Distal,intron-Proximal3.398585.98230K562HNRNPK
chr1264959166495966+intron-Distal3.539694.77135HepG2HNRNPL
chr1264946126494659+intron-Distal,intron-Proximal4.099487.55682HepG2BUD13
chr1264975186497561+intron-Distal,intron-Proximal3.613083.37120HepG2SF3B4
chr1264971716497247+intron-Distal,intron-Proximal5.5067521.12805HepG2HNRNPK
chr1264961526496177+intron-Distal5.419614.85866HepG2QKI
chr1264984406498554+intron-Distal3.760514.01088HepG2RBFOX2
chr1264967066496757+intron-Distal3.858755.84244HepG2HNRNPK
chr1264960626496137+intron-Distal6.9436427.65084HepG2QKI
chr1264959906496057+intron-Distal3.555075.67528K562HNRNPL
chr1264960606496217+intron-Distal6.5081715.08232K562QKI
chr1264953286495359+intron-Distal,intron-Proximal4.892514.94356HepG2PRPF8
chr1264960136496062+intron-Distal3.363555.35398HepG2QKI
chr1264947406494814+intron-Distal3.241335.23907HepG2EFTUD2
chr1264961776496253+intron-Distal6.1775711.15144HepG2QKI
chr1264979056497960+intron-Proximal4.776724.40745K562SF3B4
chr1264945586494612+intron-Proximal3.632519.23155HepG2BUD13
chr1264945786494589+intron-Proximal3.325337.64201HepG2PRPF8
chr1264945916494641+intron-Proximal4.416117.92018K562AQR
chr1264945736494591+intron-Proximal4.6631612.08233K562AQR
chr1264956296495652+intron-Proximal5.9447511.65826K562AQR
chr1264979126497965+intron-Proximal4.8277113.00007HepG2SF3B4
chr1264954306495490+intron-Proximal3.204274.90942HepG2SF3B4
chr1264954356495439+intron-Proximal5.311918.62858HepG2RBM5
chr1264956166495629+intron-Proximal5.8197910.44569K562AQR
chr1264954396495485+intron-Proximal5.6123011.78704HepG2RBM5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LTBR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LTBR is not available on ENCORE database.

  • 101 RBPs can affect the levels of LTBR.  








The Knockdown/knockout RNA-Seq assay for LTBR is not available on ENCORE database.





101 RBPs can affect the gene expression of LTBR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LTBRENSG00000111321.6971.02360827.399800.230802.003201.47060HepG2ACO1
LTBRENSG00000111321.61995.117201059.023800.9136011.0776010.08190HepG2AKAP1
LTBRENSG00000111321.6982.95370831.311300.241602.010801.34300HepG2AKAP8L
LTBRENSG00000111321.61279.12150876.188900.545704.743903.72780HepG2ASCC1
LTBRENSG00000111321.6934.36210648.636900.526502.935001.96660HepG2BCCIP
LTBRENSG00000111321.61884.857901154.191200.7075010.246909.18970HepG2BOP1
LTBRENSG00000111321.6901.000201368.88290-0.603404.550703.28490HepG2CCAR1
LTBRENSG00000111321.61209.64840827.249000.5481010.297909.18280HepG2CKAP4
LTBRENSG00000111321.61846.169301059.611300.8009011.8910010.57770HepG2CPSF6
LTBRENSG00000111321.61619.632801111.891400.542606.727005.07060HepG2CPSF7
LTBRENSG00000111321.61524.73400937.004400.7023011.5414010.40450HepG2CELF1
LTBRENSG00000111321.61223.116401007.516300.279703.217802.42900HepG2DAZAP1
LTBRENSG00000111321.6247.93200532.63520-1.1032012.2773010.41860HepG2DDX24
LTBRENSG00000111321.61376.53140871.652900.659105.877605.00680HepG2DDX6
LTBRENSG00000111321.6821.25580607.214700.435503.429102.65190HepG2DNAJC21
LTBRENSG00000111321.6916.14830601.912400.6059010.553109.37760HepG2DNAJC2
LTBRENSG00000111321.61618.562601024.206000.660109.967107.93560HepG2EIF2S2
LTBRENSG00000111321.61246.41120901.412300.467402.236201.61390HepG2EIF4B
LTBRENSG00000111321.6887.570201169.56230-0.398003.088101.93730HepG2ESF1
LTBRENSG00000111321.61903.148901416.391400.426106.548505.68860HepG2ETF1
LTBRENSG00000111321.61292.74580866.427200.577203.952103.16390HepG2G3BP1
LTBRENSG00000111321.6967.84310552.142400.809607.337605.66300HepG2GNB2L1
LTBRENSG00000111321.61143.83450789.947600.533908.582506.97490HepG2HDGF
LTBRENSG00000111321.6923.88580673.019900.457002.728301.33720HepG2HNRNPAB
LTBRENSG00000111321.61093.87460877.916800.317202.005401.40380HepG2HNRNPK
LTBRENSG00000111321.61146.03190880.615900.380002.112801.51380HepG2IGF2BP2
LTBRENSG00000111321.61019.17420691.933700.558609.997008.69040HepG2ILF2
LTBRENSG00000111321.6936.08980756.365200.307503.321902.20650HepG2KIF1C
LTBRENSG00000111321.62441.672501446.053500.755607.638706.24380HepG2LARP4
LTBRENSG00000111321.6903.38190641.155900.494602.356601.38260HepG2METAP2
LTBRENSG00000111321.6985.23230670.480800.555207.954406.63620HepG2PARN
LTBRENSG00000111321.61533.51290868.978500.8193020.7290019.31780HepG2PCBP1
LTBRENSG00000111321.6878.25570590.809600.571803.385402.23910HepG2PCBP2
LTBRENSG00000111321.6858.94520604.179200.507505.914204.86760HepG2PPIL4
LTBRENSG00000111321.6704.256001006.86300-0.515706.961905.79780HepG2PRPF4
LTBRENSG00000111321.61099.22120884.234400.313903.123702.54940HepG2PTBP1
LTBRENSG00000111321.61848.436201012.370700.8685032.0038030.43680HepG2PUM1
LTBRENSG00000111321.61391.694201011.632600.460105.410404.48670HepG2PUM2
LTBRENSG00000111321.6733.84950957.61310-0.384003.433602.74790HepG2QKI
LTBRENSG00000111321.6891.79650569.915500.645903.244802.48420HepG2RAVER1
LTBRENSG00000111321.61033.34460652.571000.663004.105102.87930HepG2RBM27
LTBRENSG00000111321.6679.61740984.05450-0.534006.779205.99730HepG2NELFE
LTBRENSG00000111321.6751.47580916.53750-0.286502.401101.82190HepG2RECQL
LTBRENSG00000111321.61114.42170596.169800.9024014.1030012.85500HepG2RPS19
LTBRENSG00000111321.6865.85480601.779400.524803.081802.23610HepG2RPS2
LTBRENSG00000111321.6896.84090614.355100.545702.628101.58180HepG2RPS5
LTBRENSG00000111321.6782.05360486.454900.684904.819803.81450HepG2RRP9
LTBRENSG00000111321.6823.00900603.239000.448105.427604.57830HepG2SAFB2
LTBRENSG00000111321.61606.228701121.841900.517703.586002.81510HepG2SF3A3
LTBRENSG00000111321.61316.60940920.573000.516108.111707.18170HepG2SF3B4
LTBRENSG00000111321.61028.09370703.459000.547309.590108.50680HepG2SMN1
LTBRENSG00000111321.61111.99470582.329200.933109.126307.33270HepG2SMNDC1
LTBRENSG00000111321.6981.68210500.013400.973203.190801.76240HepG2SNRNP200
LTBRENSG00000111321.62128.249001262.435900.753405.929204.77970HepG2SNRNP70
LTBRENSG00000111321.61533.385501337.067800.197501.938901.49710HepG2SRFBP1
LTBRENSG00000111321.6724.09660960.89080-0.408202.843902.36590HepG2SRSF1
LTBRENSG00000111321.61785.37030941.617000.9229027.7046026.00550HepG2SRSF5
LTBRENSG00000111321.61838.66000781.746101.2338050.8842049.09890HepG2SRSF9
LTBRENSG00000111321.6579.942501160.85170-1.0012025.6022024.39500HepG2SSB
LTBRENSG00000111321.61053.70280712.076000.565304.001702.65640HepG2STIP1
LTBRENSG00000111321.61454.751601070.880100.441907.368006.43400HepG2SUCLG1
LTBRENSG00000111321.61125.10320920.597600.289302.268901.41260HepG2SUPT6H
LTBRENSG00000111321.61127.04700634.842600.828007.404806.38390HepG2SUPV3L1
LTBRENSG00000111321.6513.19030863.71910-0.7511011.1049010.10020HepG2TAF15
LTBRENSG00000111321.61815.065701117.265300.699909.560808.32970HepG2TARDBP
LTBRENSG00000111321.6625.23530425.474600.555202.913101.89180HepG2TFIP11
LTBRENSG00000111321.61408.40380664.105101.0845033.5179031.82390HepG2TRIM56
LTBRENSG00000111321.61300.60000931.700900.481105.223603.98320HepG2TUFM
LTBRENSG00000111321.61679.378001166.230500.526005.518904.64870HepG2U2AF1
LTBRENSG00000111321.61285.59370581.335901.144903.905502.72170HepG2U2AF2
LTBRENSG00000111321.6529.20570374.978300.496902.787602.02470HepG2UCHL5
LTBRENSG00000111321.61315.10240994.901900.402405.856104.90010HepG2UPF1
LTBRENSG00000111321.6917.19760626.979600.548703.320802.15700HepG2XRCC6
LTBRENSG00000111321.61189.73220993.622000.259802.815602.13900HepG2ZC3H8
LTBRENSG00000111321.61651.728101094.202100.5940015.1924014.16720HepG2ZNF622
LTBRENSG00000111321.61622.882501294.821200.325704.057803.39400K562AGGF1
LTBRENSG00000111321.61638.343901347.307500.282102.059801.49410K562AKAP8L
LTBRENSG00000111321.61019.43680729.770200.482204.845803.41110K562DDX3X
LTBRENSG00000111321.61934.526701634.738400.242802.772602.12120K562DDX47
LTBRENSG00000111321.6854.51990628.268500.443602.688901.78960K562EFTUD2
LTBRENSG00000111321.61432.817101124.630800.349304.068103.22140K562EIF2S2
LTBRENSG00000111321.6590.94170369.653400.676707.110805.84790K562EIF3G
LTBRENSG00000111321.6992.79650792.860800.324302.887002.27140K562FXR1
LTBRENSG00000111321.6168.81030344.17600-1.027702.642701.95570K562G3BP2
LTBRENSG00000111321.6788.57950999.28090-0.341602.369001.81060K562HNRNPC
LTBRENSG00000111321.61960.585601525.200200.362203.063702.22840K562HSPD1
LTBRENSG00000111321.6849.25460523.195300.698705.620903.94120K562IGF2BP2
LTBRENSG00000111321.6770.91790549.514600.488304.285003.23560K562MAGOH
LTBRENSG00000111321.62108.960101601.814200.396704.220103.05850K562MBNL1
LTBRENSG00000111321.6651.68230488.869300.414602.763301.78380K562PCBP2
LTBRENSG00000111321.61047.840401585.59340-0.597605.740304.53610K562PCBP3
LTBRENSG00000111321.6831.850001216.17080-0.548006.907005.64910K562POLR2G
LTBRENSG00000111321.6825.70300611.384200.433402.474701.76470K562PRPF8
LTBRENSG00000111321.61191.71900896.032200.411302.580501.71310K562PSIP1
LTBRENSG00000111321.6947.41520533.913500.8273012.4834011.12340K562PTBP1
LTBRENSG00000111321.61969.409001336.249800.559506.556005.76080K562PUS1
LTBRENSG00000111321.61640.139401301.899200.333103.550102.89220K562RBM15
LTBRENSG00000111321.6747.64850511.771900.546803.295402.37150K562RBM22
LTBRENSG00000111321.6676.71750499.023400.439302.864301.45880K562RBM34
LTBRENSG00000111321.61371.725601083.742500.339902.844001.74630K562SAFB
LTBRENSG00000111321.61322.36610820.422300.688602.388501.30510K562SF1
LTBRENSG00000111321.6547.87070357.371600.616302.792001.93260K562SF3B4
LTBRENSG00000111321.61117.74110775.274100.527704.561603.15300K562SRFBP1
LTBRENSG00000111321.6984.74160523.451800.9116014.0997012.50010K562SRSF1
LTBRENSG00000111321.6999.12580764.643700.385803.023501.91110K562SRSF4
LTBRENSG00000111321.6731.55200494.456100.565004.925503.44880K562SRSF5
LTBRENSG00000111321.61500.449301219.897200.298502.681101.87570K562SYNCRIP
LTBRENSG00000111321.6919.25970529.684400.795209.209507.81520K562TARDBP
LTBRENSG00000111321.6711.88640510.962200.478304.030503.01440K562TIA1
LTBRENSG00000111321.6566.74900861.79090-0.604605.147603.83320K562TIAL1
LTBRENSG00000111321.6731.87530501.602300.545004.541603.07860K562TRA2A
LTBRENSG00000111321.61196.90840915.929200.385903.076002.06770K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LTBR is not available on ENCORE database.





17 RBPs can affect the splicing of LTBR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELTBRENSG00000111321.6chr12+6497563649767164955126495610649796564979910.074000.000290.03136includedHepG2G3BP1
SELTBRENSG00000111321.6chr12+649756364976716495512649561064979656497991-0.438000.000000.00000excludedHepG2U2AF1
SELTBRENSG00000111321.6chr12+649523164953286494392649454564955126495610-0.053000.000000.00001excludedHepG2U2AF1
SELTBRENSG00000111321.6chr12+649696364970766495512649561064975636497671-0.057000.000130.00641excludedK562AKAP8L
SELTBRENSG00000111321.6chr12+6497563649767164955126495610649796564979910.113000.000040.01868includedHepG2ILF3
SELTBRENSG00000111321.6chr12+6496963649707664955126495610649756364976710.085000.000560.01662includedHepG2HNRNPK
SELTBRENSG00000111321.6chr12+6497563649767164955126495610649796564979910.114000.000260.02736includedHepG2TBRG4
SELTBRENSG00000111321.6chr12+649523164953286494392649454564955126495610-0.091000.000000.00009excludedHepG2U2AF2
SELTBRENSG00000111321.6chr12+649796564979916495434649561064992776499506-0.054000.003280.03293excludedK562AQR
SELTBRENSG00000111321.6chr12+649696364970766495512649561064975636497671-0.056000.000530.01000excludedK562PUS1
SELTBRENSG00000111321.6chr12+649756364976716495512649561064979656497991-0.228000.000110.00364excludedK562U2AF1
SELTBRENSG00000111321.6chr12+649756364976716495512649561064979656497991-0.140000.000030.00252excludedHepG2PCBP1
SELTBRENSG00000111321.6chr12+649756364976716495512649561064979656497991-0.161000.000000.00048excludedHepG2SRSF9
RILTBRENSG00000111321.6chr12+6494187649454564941876494313649439264945450.066000.001140.00756includedK562AQR
MXELTBRENSG00000111321.6chr12+649796564979916499277649950664955126495610649982565002770.253000.000000.000001includedHepG2U2AF1
MXELTBRENSG00000111321.6chr12+649796564979916499277649949664955126495610649982565003900.179000.002750.046291includedHepG2U2AF1
MXELTBRENSG00000111321.6chr12+64979656497991649927764995066497563649767164998256500390-0.172000.000670.015672includedHepG2U2AF1
MXELTBRENSG00000111321.6chr12+64975636497671649796564979916495512649561064992776499506-0.327000.000000.000002includedHepG2U2AF1
MXELTBRENSG00000111321.6chr12+649551264956106497563649767164943926494545649796564979910.241000.000300.007571includedK562U2AF1
MXELTBRENSG00000111321.6chr12+64975636497671649796564979916495512649561064992776499506-0.138000.013560.080832includedK562AQR
MXELTBRENSG00000111321.6chr12+64979656497991649927764995066497563649767164998256500390-0.175000.000250.017772includedHepG2BCCIP
MXELTBRENSG00000111321.6chr12+649796564979916499277649950664955126495610649982565002770.167000.003570.094171includedHepG2SF3B4
MXELTBRENSG00000111321.6chr12+64979656497991649927764995066495512649561064998256500277-0.124000.000740.048252includedHepG2TBRG4
MXELTBRENSG00000111321.6chr12+64943926494545649523164953286494187649431364955126495610-0.108000.000000.000052includedK562SAFB
MXELTBRENSG00000111321.6chr12+64979656497991649927764995066497563649767164998256500390-0.194000.000040.003372includedHepG2HNRNPC
MXELTBRENSG00000111321.6chr12+64943926494545649523164953286494187649431364955126495610-0.084000.005200.086932includedK562PPIL4
MXELTBRENSG00000111321.6chr12+64943926494545649523164953286494187649431364955126495610-0.165000.000270.009522includedK562SUPV3L1
MXELTBRENSG00000111321.6chr12+64979656497991649927764995066497563649767164998256500390-0.133000.003480.062682includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LTBR is not avaliable on ENCORE database.