IRF3

General Information

Gene Name : IRF3
Gene ID : ENSG00000126456.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: IRF3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	IRF3	ENSG00000126456.15	15.91	56.62	36.27	ENCSR000AEF
HepG2	IRF3	ENSG00000126456.15	70.31	40.10	55.20	ENCSR985KAT
K562	IRF3	ENSG00000126456.15	84.89	80.21	82.55	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for IRF3 is not avaliable on ENCORE database.

Proteins bound to RNA

IRF3 RNA is bound by 30 proteins.

eCLIP assay for IRF3 is not avaliable on ENCORE database.

30 proteins are bound to IRF3 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	50165148	50165192	-	3'-UTR,intron-Distal,intron-Proximal	3.68342	6.32052	K562	AQR
chr19	50166454	50166509	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.09642	5.24452	HepG2	PPIG
chr19	50165159	50165227	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.54272	7.39410	K562	BUD13
chr19	50164064	50164130	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.41524	15.05264	K562	SF3B4
chr19	50164071	50164138	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.58263	4.68890	K562	SMNDC1
chr19	50163079	50163147	-	3'-UTR,CDS,intron-Distal	4.77465	5.86025	HepG2	SF3B4
chr19	50165151	50165235	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.12578	3.26655	HepG2	LSM11
chr19	50164067	50164124	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.54878	6.22359	HepG2	BUD13
chr19	50166751	50166819	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.81411	9.73349	HepG2	EFTUD2
chr19	50165786	50165858	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.40235	4.51483	HepG2	PABPN1
chr19	50164063	50164128	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.36137	5.08326	K562	LSM11
chr19	50163989	50164034	-	3'-UTR,CDS,intron-Distal	4.97893	4.67689	HepG2	PPIG
chr19	50163036	50163086	-	3'-UTR,CDS,intron-Distal	4.31618	4.01415	K562	LSM11
chr19	50162902	50162968	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.11090	7.71026	K562	PABPC4
chr19	50163935	50163988	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.79380	5.68502	HepG2	PRPF8
chr19	50166725	50166808	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.57205	17.18244	K562	AQR
chr19	50166759	50166813	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.11455	5.40996	HepG2	PRPF4
chr19	50163050	50163094	-	3'-UTR,CDS,intron-Distal	4.80921	4.19739	K562	EIF4G2
chr19	50163984	50164067	-	3'-UTR,CDS,intron-Distal	4.30154	4.78834	HepG2	PABPN1
chr19	50164072	50164122	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.73251	6.03362	HepG2	AQR
chr19	50165161	50165238	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.10281	13.83580	HepG2	PRPF8
chr19	50168602	50168646	-	5'-UTR,intron-Distal	4.12389	3.57264	HepG2	GTF2F1
chr19	50168467	50168579	-	5'-UTR,intron-Distal,intron-Proximal	4.49141	11.82327	K562	GTF2F1
chr19	50168236	50168390	-	5'-UTR,intron-Distal,intron-Proximal	3.95816	14.02042	HepG2	PRPF4
chr19	50168486	50168537	-	5'-UTR,intron-Distal,intron-Proximal	3.83964	7.11537	HepG2	PRPF4
chr19	50168591	50168691	-	5'-UTR,intron-Distal	3.33252	7.28315	HepG2	PRPF4
chr19	50168175	50168274	-	5'-UTR,intron-Distal,intron-Proximal	3.32179	4.48600	HepG2	HNRNPU
chr19	50168141	50168252	-	5'-UTR,intron-Distal,intron-Proximal	3.22814	4.02608	HepG2	FUS
chr19	50168137	50168211	-	5'-UTR,intron-Distal,intron-Proximal	3.68726	6.04577	K562	FAM120A
chr19	50167877	50167978	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.29793	5.63373	HepG2	SRSF1
chr19	50167884	50167986	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.24307	5.63844	K562	SRSF1
chr19	50168127	50168179	-	5'-UTR,intron-Distal,intron-Proximal	3.80584	3.15171	K562	SRSF1
chr19	50168174	50168285	-	5'-UTR,intron-Distal,intron-Proximal	3.58029	12.79191	K562	CSTF2T
chr19	50169040	50169114	-	5'-UTR,intron-Distal,intron-Proximal	5.73820	11.69255	HepG2	NCBP2
chr19	50167888	50167931	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.54637	16.58923	K562	AQR
chr19	50168109	50168163	-	5'-UTR,intron-Distal,intron-Proximal	3.78520	3.37829	HepG2	DROSHA
chr19	50168143	50168258	-	5'-UTR,intron-Distal,intron-Proximal	3.03015	4.18180	K562	AKAP8L
chr19	50168285	50168389	-	5'-UTR,intron-Distal,intron-Proximal	5.94473	17.70547	K562	CSTF2T
chr19	50167729	50167805	-	5'-UTR,intron-Distal,intron-Proximal	3.77493	6.65196	K562	GTF2F1
chr19	50168158	50168349	-	5'-UTR,intron-Distal,intron-Proximal	3.15025	6.57543	K562	TAF15
chr19	50168331	50168372	-	5'-UTR,intron-Distal	3.55938	3.46580	HepG2	CSTF2T
chr19	50167759	50167804	-	5'-UTR,intron-Distal,intron-Proximal	3.43245	4.69054	HepG2	CSTF2T
chr19	50168162	50168271	-	5'-UTR,intron-Distal,intron-Proximal	3.57204	11.08776	K562	DROSHA
chr19	50168297	50168365	-	5'-UTR,intron-Distal,intron-Proximal	4.65218	6.11395	HepG2	GTF2F1
chr19	50168125	50168304	-	5'-UTR,intron-Distal,intron-Proximal	4.45101	5.29232	K562	GRWD1
chr19	50168122	50168171	-	5'-UTR,intron-Distal,intron-Proximal	5.01593	6.46301	HepG2	PPIG
chr19	50168475	50168533	-	5'-UTR,intron-Distal,intron-Proximal	3.21841	3.68010	HepG2	GTF2F1
chr19	50168501	50168563	-	5'-UTR,intron-Distal,intron-Proximal	3.70990	3.55447	K562	FUS
chr19	50168120	50168221	-	5'-UTR,intron-Distal,intron-Proximal	4.62854	7.87612	K562	UCHL5
chr19	50168107	50168176	-	5'-UTR,intron-Distal,intron-Proximal	4.30548	7.26476	HepG2	AQR
chr19	50168459	50168546	-	5'-UTR,intron-Distal,intron-Proximal	3.11132	9.65864	K562	DROSHA
chr19	50168565	50168596	-	5'-UTR,intron-Distal,intron-Proximal	4.38130	5.40707	K562	CSTF2T
chr19	50168447	50168537	-	5'-UTR,intron-Distal,intron-Proximal	3.73400	11.62124	K562	CSTF2T
chr19	50167728	50167798	-	5'-UTR,intron-Distal,intron-Proximal	4.08343	3.84109	HepG2	PCBP2
chr19	50168766	50168811	-	5'-UTR,intron-Distal	4.12993	3.28946	K562	FTO
chr19	50168982	50169111	-	5'-UTR,intron-Distal,intron-Proximal	3.18338	8.35983	K562	DDX3X
chr19	50167731	50167769	-	5'-UTR,intron-Distal,intron-Proximal	3.86921	3.02711	K562	EWSR1
chr19	50168137	50168236	-	5'-UTR,intron-Distal,intron-Proximal	3.76412	9.98522	HepG2	PRPF4
chr19	50168137	50168230	-	5'-UTR,intron-Distal,intron-Proximal	3.54006	13.31423	K562	AQR
chr19	50168627	50168648	-	5'-UTR,intron-Distal	3.28206	4.07684	K562	DROSHA
chr19	50167706	50167756	-	5'-UTR,intron-Distal,intron-Proximal	4.04615	4.33898	HepG2	FAM120A
chr19	50167875	50167936	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.47507	19.82258	K562	PRPF8
chr19	50167879	50167975	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.40738	25.65328	HepG2	PRPF8
chr19	50167732	50167772	-	5'-UTR,intron-Distal,intron-Proximal	3.26969	7.17950	K562	AQR
chr19	50168129	50168181	-	5'-UTR,intron-Distal,intron-Proximal	4.01125	6.75344	HepG2	EFTUD2
chr19	50165574	50165603	-	CDS,intron-Distal,intron-Proximal	4.60770	4.02817	HepG2	PRPF8
chr19	50164095	50164123	-	CDS,intron-Distal,intron-Proximal	4.10683	4.36329	HepG2	PRPF4
chr19	50164092	50164204	-	CDS,intron-Distal,intron-Proximal	3.15498	4.44473	K562	EIF4G2
chr19	50167986	50168089	-	CDS,intron-Distal,intron-Proximal	3.22649	5.41523	K562	SRSF1
chr19	50165324	50165369	-	CDS,intron-Distal,intron-Proximal	5.37076	5.10740	K562	DDX24
chr19	50167941	50167961	-	CDS,intron-Distal,intron-Proximal	3.26718	3.05161	HepG2	PPIG
chr19	50165320	50165387	-	CDS,intron-Distal,intron-Proximal	4.53693	8.44359	HepG2	EFTUD2
chr19	50165330	50165425	-	CDS,intron-Distal,intron-Proximal	3.74853	8.69914	K562	AQR
chr19	50164091	50164111	-	CDS,intron-Distal,intron-Proximal	4.06086	4.98250	K562	AQR
chr19	50166849	50166909	-	intron-Distal,intron-Proximal	4.85234	9.81110	K562	GTF2F1
chr19	50166778	50166849	-	intron-Distal,intron-Proximal	5.78847	10.32927	K562	GTF2F1
chr19	50167608	50167646	-	intron-Distal,intron-Proximal	3.81315	3.01994	HepG2	GTF2F1
chr19	50166806	50166862	-	intron-Distal,intron-Proximal	3.56991	7.29030	K562	CSTF2T
chr19	50163307	50163368	-	intron-Distal	4.20463	3.88340	K562	TARDBP
chr19	50166795	50166859	-	intron-Distal,intron-Proximal	3.19553	3.92299	HepG2	CSTF2T
chr19	50166833	50166894	-	intron-Distal,intron-Proximal	3.09694	3.40641	HepG2	GTF2F1
chr19	50163921	50163969	-	intron-Distal,intron-Proximal	5.72944	10.84943	K562	AQR
chr19	50163094	50163179	-	intron-Distal	5.31995	6.10540	K562	EIF4G2
chr19	50166859	50166914	-	intron-Distal,intron-Proximal	4.31189	8.83932	HepG2	PRPF4
chr19	50163179	50163308	-	intron-Distal	5.12094	20.12614	K562	EIF4G2
chr19	50166815	50166859	-	intron-Distal,intron-Proximal	3.39393	5.82976	HepG2	PRPF4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for IRF3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for IRF3 is not available on ENCORE database.
81 RBPs can affect the levels of IRF3.

The Knockdown/knockout RNA-Seq assay for IRF3 is not available on ENCORE database.

81 RBPs can affect the gene expression of IRF3 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
IRF3	ENSG00000126456.11	1110.52430	890.50930	0.31840	3.63680	2.95680	HepG2	ACO1
IRF3	ENSG00000126456.11	1592.13180	890.15400	0.83870	6.31560	5.54890	HepG2	AKAP1
IRF3	ENSG00000126456.11	923.38850	679.40080	0.44260	2.88640	1.82730	HepG2	AKAP8
IRF3	ENSG00000126456.11	965.77620	640.15230	0.59320	2.49470	1.60730	HepG2	BCCIP
IRF3	ENSG00000126456.11	675.12990	890.38540	-0.39930	4.90240	4.06420	HepG2	CKAP4
IRF3	ENSG00000126456.11	770.32040	563.19720	0.45170	1.98140	1.33880	HepG2	CNOT7
IRF3	ENSG00000126456.11	1068.32930	795.14990	0.42600	3.30910	2.09760	HepG2	CPSF7
IRF3	ENSG00000126456.11	1300.07780	863.10440	0.59090	9.85080	8.77970	HepG2	CELF1
IRF3	ENSG00000126456.11	319.39530	564.06900	-0.82050	8.40930	6.83090	HepG2	DDX24
IRF3	ENSG00000126456.11	1201.81130	852.54860	0.49530	3.35680	2.67640	HepG2	DDX3X
IRF3	ENSG00000126456.11	1030.84330	629.44900	0.71160	5.20320	4.18380	HepG2	DDX55
IRF3	ENSG00000126456.11	1532.44140	732.71370	1.06440	14.07500	12.81730	HepG2	DDX6
IRF3	ENSG00000126456.11	710.25230	851.99410	-0.26250	2.05450	1.45720	HepG2	DKC1
IRF3	ENSG00000126456.11	556.73950	414.13830	0.42680	3.41450	2.63880	HepG2	DNAJC21
IRF3	ENSG00000126456.11	668.51860	410.51640	0.70340	10.81700	9.62460	HepG2	DNAJC2
IRF3	ENSG00000126456.11	901.41750	704.02140	0.35650	1.82950	1.33460	HepG2	EIF2S1
IRF3	ENSG00000126456.11	1138.62600	1403.08860	-0.30130	3.51200	2.84720	HepG2	ETF1
IRF3	ENSG00000126456.11	1064.57030	785.34150	0.43880	2.59810	1.92810	HepG2	FXR1
IRF3	ENSG00000126456.11	1000.85130	728.24670	0.45860	2.95610	2.26980	HepG2	G3BP1
IRF3	ENSG00000126456.11	427.63830	770.30230	-0.84900	7.93500	6.88720	HepG2	GPKOW
IRF3	ENSG00000126456.11	743.69780	476.66840	0.64160	4.13950	2.43820	HepG2	HNRNPA0
IRF3	ENSG00000126456.11	654.89400	465.42850	0.49260	2.81400	1.40030	HepG2	HNRNPAB
IRF3	ENSG00000126456.11	1360.36820	738.05230	0.88210	10.82130	9.52110	HepG2	HNRNPK
IRF3	ENSG00000126456.11	1175.74850	845.35970	0.47580	7.87760	6.79400	HepG2	HNRNPL
IRF3	ENSG00000126456.11	548.47200	735.11770	-0.42260	2.68280	2.06120	HepG2	HNRNPLL
IRF3	ENSG00000126456.11	590.79840	471.91760	0.32400	2.78250	2.04770	HepG2	ILF2
IRF3	ENSG00000126456.11	1267.37580	920.23460	0.46170	5.63870	4.55750	HepG2	NOL12
IRF3	ENSG00000126456.11	950.53540	514.89710	0.88440	5.89360	4.56300	HepG2	PABPC1
IRF3	ENSG00000126456.11	1065.89450	725.87670	0.55420	8.45430	7.48820	HepG2	PCBP1
IRF3	ENSG00000126456.11	490.96630	665.95540	-0.43980	4.13820	3.21250	HepG2	PRPF4
IRF3	ENSG00000126456.11	1008.53210	738.62040	0.44930	5.15980	4.46100	HepG2	PTBP1
IRF3	ENSG00000126456.11	1324.40440	932.51870	0.50600	10.05810	9.07540	HepG2	PUM1
IRF3	ENSG00000126456.11	1491.52820	959.87130	0.63580	9.52720	8.06880	HepG2	RBM15
IRF3	ENSG00000126456.11	966.73210	822.00220	0.23390	1.79490	1.33890	HepG2	NELFE
IRF3	ENSG00000126456.11	808.27890	605.16590	0.41740	2.35900	1.61620	HepG2	RPS2
IRF3	ENSG00000126456.11	678.10490	411.42620	0.72080	10.52950	9.39680	HepG2	SAFB2
IRF3	ENSG00000126456.11	537.31070	727.59520	-0.43740	3.08670	2.34220	HepG2	SF3B1
IRF3	ENSG00000126456.11	697.41750	479.78090	0.53950	6.89030	5.94560	HepG2	SMN1
IRF3	ENSG00000126456.11	852.27930	556.27760	0.61540	2.35810	1.48070	HepG2	SMNDC1
IRF3	ENSG00000126456.11	512.67180	809.58660	-0.65910	3.87130	2.93930	HepG2	SNRNP70
IRF3	ENSG00000126456.11	509.96680	802.65300	-0.65440	8.75630	8.02160	HepG2	SRSF1
IRF3	ENSG00000126456.11	1085.71610	867.34790	0.32390	3.39780	2.71640	HepG2	SRSF5
IRF3	ENSG00000126456.11	794.73650	653.00960	0.28330	2.51500	1.98290	HepG2	SRSF9
IRF3	ENSG00000126456.11	990.41020	1149.93720	-0.21550	1.94010	1.49090	HepG2	SSB
IRF3	ENSG00000126456.11	885.96860	492.45460	0.84720	7.66990	5.76680	HepG2	STIP1
IRF3	ENSG00000126456.11	1281.37160	986.40750	0.37730	5.42120	4.60370	HepG2	SUCLG1
IRF3	ENSG00000126456.11	556.77310	721.48370	-0.37390	2.90150	2.32860	HepG2	TAF15
IRF3	ENSG00000126456.11	523.02490	716.63250	-0.45440	3.18960	2.41680	HepG2	TARDBP
IRF3	ENSG00000126456.11	595.88980	448.87750	0.40860	2.96220	2.44710	HepG2	TIAL1
IRF3	ENSG00000126456.11	864.78020	452.93700	0.93290	19.10410	17.79150	HepG2	TRIM56
IRF3	ENSG00000126456.11	1618.83060	908.41590	0.83340	5.57570	4.36280	HepG2	UBE2L3
IRF3	ENSG00000126456.11	674.68330	370.06410	0.86630	8.09990	6.80450	HepG2	UCHL5
IRF3	ENSG00000126456.11	856.03470	616.75690	0.47290	2.57200	1.87190	HepG2	XRN2
IRF3	ENSG00000126456.11	1017.48880	876.84600	0.21450	1.98440	1.50040	HepG2	ZNF622
IRF3	ENSG00000126456.11	2221.77100	2656.77180	-0.25800	3.02320	2.00510	K562	CELF1
IRF3	ENSG00000126456.11	1728.30250	1341.35500	0.36560	4.63500	3.73400	K562	EIF2S2
IRF3	ENSG00000126456.11	616.79980	476.14350	0.37330	2.44050	1.69130	K562	EIF3G
IRF3	ENSG00000126456.11	408.33750	624.53260	-0.61300	4.01410	2.62470	K562	FKBP4
IRF3	ENSG00000126456.11	159.48460	403.66170	-1.33970	9.07300	7.64010	K562	G3BP2
IRF3	ENSG00000126456.11	1151.34110	1391.70470	-0.27350	2.52730	1.44060	K562	GLRX3
IRF3	ENSG00000126456.11	875.36750	1170.45080	-0.41910	4.10540	1.80010	K562	HNRNPH1
IRF3	ENSG00000126456.11	867.71360	641.25600	0.43620	3.56240	1.76620	K562	LSM11
IRF3	ENSG00000126456.11	985.98400	698.48300	0.49720	2.41970	1.63080	K562	MAGOH
IRF3	ENSG00000126456.11	1212.54600	1463.19320	-0.27110	2.95330	2.11810	K562	MTPAP
IRF3	ENSG00000126456.11	824.66470	1121.42040	-0.44340	2.51520	1.68330	K562	NAA15
IRF3	ENSG00000126456.11	1063.07700	707.93210	0.58650	4.98910	2.84520	K562	NUSAP1
IRF3	ENSG00000126456.11	986.14910	1415.05930	-0.52100	4.38940	3.34170	K562	PCBP3
IRF3	ENSG00000126456.11	817.80100	1085.35550	-0.40830	3.28390	2.40640	K562	POLR2G
IRF3	ENSG00000126456.11	1352.78250	949.28680	0.51090	3.45330	2.52130	K562	PPIG
IRF3	ENSG00000126456.11	1037.22520	644.50820	0.68640	7.98970	6.28910	K562	PSIP1
IRF3	ENSG00000126456.11	922.00930	678.66660	0.44200	2.69590	2.03960	K562	PTBP1
IRF3	ENSG00000126456.11	1967.30400	2507.49710	-0.35000	4.64900	3.23580	K562	PUM1
IRF3	ENSG00000126456.11	1034.94590	650.41920	0.67000	4.08550	3.04320	K562	RBM22
IRF3	ENSG00000126456.11	820.01140	588.21870	0.47920	4.26280	3.02820	K562	RCC2
IRF3	ENSG00000126456.11	749.09780	534.49410	0.48690	3.06410	2.00540	K562	RPS3
IRF3	ENSG00000126456.11	588.25480	420.10920	0.48560	4.23950	3.17540	K562	SF3B4
IRF3	ENSG00000126456.11	761.36010	557.59610	0.44930	3.28420	2.14160	K562	SRFBP1
IRF3	ENSG00000126456.11	1396.15610	1643.51680	-0.23530	2.86370	1.91470	K562	SRPK2
IRF3	ENSG00000126456.11	875.29460	636.83540	0.45870	2.31940	1.39350	K562	SUPV3L1
IRF3	ENSG00000126456.11	888.69030	1088.69970	-0.29290	2.33460	1.57990	K562	SYNCRIP
IRF3	ENSG00000126456.11	1292.47840	673.26670	0.94080	9.71920	8.26460	K562	TARDBP
IRF3	ENSG00000126456.11	1033.23830	649.48140	0.66970	6.62300	5.27690	K562	TIA1
IRF3	ENSG00000126456.11	862.15420	658.75930	0.38810	2.66240	1.73820	K562	TRIM56
IRF3	ENSG00000126456.11	1192.06570	1475.02100	-0.30730	2.62170	1.76720	K562	WDR3
IRF3	ENSG00000126456.11	1329.22160	1533.83700	-0.20660	2.15710	1.40240	K562	WDR43
IRF3	ENSG00000126456.11	943.89560	686.77600	0.45870	2.72740	1.53170	K562	XRN2
IRF3	ENSG00000126456.11	1750.46410	2194.59080	-0.32620	2.87570	1.99310	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for IRF3 is not available on ENCORE database.

24 RBPs can affect the splicing of IRF3 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	IRF3	ENSG00000126456.11	chr19	-	50166599	50166771			50166444	50166515	50168887	50168962	-0.61100	0.00000	0.00000	excluded	K562	SRSF1
SE	IRF3	ENSG00000126456.11	chr19	-	50165204	50165585			50163969	50164085	50165681	50165874	-0.23700	0.00490	0.07466	excluded	K562	SRSF1
SE	IRF3	ENSG00000126456.11	chr19	-	50166599	50166771			50166444	50166515	50168887	50168962	-0.27700	0.00001	0.00095	excluded	K562	PRPF8
SE	IRF3	ENSG00000126456.11	chr19	-	50165204	50165585			50163969	50164085	50165681	50165874	-0.17900	0.00076	0.03051	excluded	K562	PRPF8
SE	IRF3	ENSG00000126456.11	chr19	-	50167930	50168103			50166629	50166771	50168887	50169059	-0.24700	0.00000	0.00023	excluded	HepG2	RBM22
SE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164085			50162835	50163090	50165204	50165585	-0.13300	0.00000	0.00000	excluded	K562	AQR
SE	IRF3	ENSG00000126456.11	chr19	-	50167930	50168103			50166599	50166771	50168928	50169116	-0.19400	0.00008	0.00140	excluded	K562	AQR
SE	IRF3	ENSG00000126456.11	chr19	-	50165204	50165585			50163969	50164085	50165681	50165874	-0.09400	0.00339	0.09690	excluded	K562	FXR1
SE	IRF3	ENSG00000126456.11	chr19	-	50166599	50166771			50166444	50166515	50168887	50168962	-0.10000	0.00375	0.04982	excluded	K562	PUS1
SE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164085			50162835	50163090	50165681	50165874	-0.18800	0.00080	0.04343	excluded	K562	EFTUD2
SE	IRF3	ENSG00000126456.11	chr19	-	50166599	50166771			50166444	50166515	50168887	50168962	-0.23900	0.00008	0.00735	excluded	K562	EFTUD2
SE	IRF3	ENSG00000126456.11	chr19	-	50167930	50168103			50166629	50166771	50168887	50169059	-0.18100	0.00160	0.08906	excluded	K562	HNRNPL
SE	IRF3	ENSG00000126456.11	chr19	-	50166599	50166771			50166444	50166515	50168887	50168962	-0.50600	0.00000	0.00000	excluded	HepG2	SRSF1
SE	IRF3	ENSG00000126456.11	chr19	-	50165204	50165585			50163969	50164085	50165681	50165874	-0.10100	0.00177	0.04014	excluded	HepG2	SRSF1
SE	IRF3	ENSG00000126456.11	chr19	-	50167930	50168103			50166629	50166771	50168887	50169059	-0.18900	0.00055	0.08151	excluded	K562	SRSF7
SE	IRF3	ENSG00000126456.11	chr19	-	50167930	50168103			50166629	50166771	50168887	50169059	-0.28000	0.00154	0.05238	excluded	K562	TARDBP
SE	IRF3	ENSG00000126456.11	chr19	-	50166599	50166771			50166444	50166515	50168887	50168962	-0.19800	0.00113	0.02135	excluded	K562	HNRNPC
A3SS	IRF3	ENSG00000126456.11	chr19	-	50163969	50164101			50163969	50164085	50165204	50165585	0.47700	0.00164	0.05569	longer	K562	U2AF2
A3SS	IRF3	ENSG00000126456.11	chr19	-	50163969	50164101			50163969	50164085	50165204	50165585	0.55500	0.00037	0.02382	longer	K562	SF3B4
A3SS	IRF3	ENSG00000126456.11	chr19	-	50163969	50164101			50163969	50164085	50165204	50165585	0.15600	0.00400	0.02375	longer	K562	AQR
A3SS	IRF3	ENSG00000126456.11	chr19	-	50163969	50164101			50163969	50164085	50165204	50165278	-0.20200	0.00037	0.08096	shorter	K562	TARDBP
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.17800	0.00003	0.00083	included	HepG2	SF3A3
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.08000	0.00221	0.04971	included	HepG2	UCHL5
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.08900	0.00104	0.01549	included	HepG2	PRPF8
RI	IRF3	ENSG00000126456.11	chr19	-	50167930	50169114			50167930	50168103	50168740	50169114	0.17000	0.00062	0.00775	included	HepG2	U2AF1
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.05900	0.00082	0.02085	included	HepG2	KHSRP
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	-0.09200	0.00003	0.00644	excluded	K562	XRCC6
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.09500	0.00000	0.00009	included	HepG2	NCBP2
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.07600	0.00010	0.00134	included	HepG2	SF3B4
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.09600	0.00037	0.00552	included	HepG2	RBM22
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.06100	0.00045	0.00697	included	HepG2	HNRNPK
RI	IRF3	ENSG00000126456.11	chr19	-	50166444	50166771			50166444	50166515	50166599	50166771	0.17800	0.00000	0.00000	included	K562	AQR
MXE	IRF3	ENSG00000126456.11	chr19	-	50167699	50167930	50167930	50168103	50166599	50166771	50168887	50168962	-0.13200	0.00008	0.01142	2included	HepG2	RBM22
MXE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164085	50165204	50165585	50162828	50163090	50165681	50165874	-0.19900	0.00012	0.02078	2included	K562	AARS
MXE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164085	50165204	50165585	50162828	50163090	50165681	50165874	0.19200	0.00105	0.03339	1included	HepG2	HNRNPU
MXE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164085	50165204	50165585	50162828	50163090	50165681	50165874	-0.23500	0.00002	0.00200	2included	K562	DDX55
MXE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164101	50165204	50165585	50162828	50163090	50165681	50165874	-0.23900	0.00002	0.00169	2included	K562	DDX55
MXE	IRF3	ENSG00000126456.11	chr19	-	50163969	50164085	50165204	50165585	50162828	50163090	50165681	50165874	0.11500	0.00229	0.03960	1included	K562	HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

IRF3

General Information

Functions

Localization

Domains (AlphaFold: IRF3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for IRF3 is not avaliable on ENCORE database.

30 proteins are bound to IRF3 RNA:

eCLIP assay for IRF3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for IRF3 is not available on ENCORE database.

81 RBPs can affect the gene expression of IRF3 :

The Knockdown/knockout RNA-Seq assay for IRF3 is not available on ENCORE database.

24 RBPs can affect the splicing of IRF3 :

The Knockdown/knockout RNA-Seq assay for IRF3 is not avaliable on ENCORE database.