ICMT

General Information

Gene Name       : ICMT
Gene ID             : ENSG00000116237.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ICMT)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ICMTENSG00000116237.1519.7226.7923.25ENCSR000AEF
HepG2ICMTENSG00000116237.1540.1746.7543.46ENCSR985KAT
K562ICMTENSG00000116237.1535.0738.3836.73ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ICMT is not avaliable on ENCORE database.



Proteins bound to RNA
  • ICMT RNA is bound by 9 proteins.  







eCLIP assay for ICMT is not avaliable on ENCORE database.





9 proteins are bound to ICMT RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr162841036284187-3'-UTR,intron-Distal5.686589.15742K562IGF2BP1
chr162844356284484-3'-UTR,intron-Distal3.672416.82055K562YBX3
chr162848216284906-3'-UTR,intron-Distal3.168896.20608HepG2IGF2BP1
chr162836416283704-3'-UTR,intron-Distal,intron-Proximal5.2664316.45025K562CPSF6
chr162837106283808-3'-UTR,intron-Distal6.7276571.74569K562CPSF6
chr162843396284401-3'-UTR,intron-Distal3.288983.61668HepG2IGF2BP1
chr162837336283801-3'-UTR,intron-Distal4.765665.94928K562UPF1
chr162843926284428-3'-UTR,intron-Distal4.8891722.86621K562YBX3
chr162847586284805-3'-UTR,intron-Distal4.377154.79072HepG2IGF2BP3
chr162824326282492-3'-UTR,intron-Distal3.097585.99201HepG2UPF1
chr162850956285116-3'-UTR,intron-Distal3.444035.58482K562YBX3
chr162844316284435-3'-UTR,intron-Distal5.7578232.13277K562YBX3
chr162831956283268-3'-UTR,intron-Distal3.337138.74425K562AKAP1
chr162846266284658-3'-UTR,intron-Distal,intron-Proximal4.115763.09815K562IGF2BP1
chr162851166285123-3'-UTR,intron-Distal3.304784.97511K562YBX3
chr162838316283868-3'-UTR,intron-Distal3.602816.11515K562CPSF6
chr162820096282123-3'-UTR,intron-Distal3.690137.91779K562UPF1
chr162850816285095-3'-UTR,intron-Distal3.916625.55970K562YBX3
chr162848316284888-3'-UTR,intron-Distal4.234468.57807K562YBX3
chr162816276281662-3'-UTR,intron-Distal3.939333.66655K562YBX3
chr162831936283274-3'-UTR,intron-Distal5.2805613.80561HepG2UPF1
chr162845336284619-3'-UTR,intron-Distal,intron-Proximal3.871104.19285K562IGF2BP1
chr162827586282814-3'-UTR,intron-Distal4.699434.46422K562UPF1
chr162847446284810-3'-UTR,intron-Distal4.1217110.83603HepG2IGF2BP1
chr162849676285030-3'-UTR,intron-Distal4.158508.14591K562YBX3
chr162921246292168-5'-UTR,CDS,intron-Distal3.650914.30677K562YBX3
chr162957846295989-5'-UTR,CDS,intron-Distal4.4601716.10484K562DDX3X
chr162936296293682-5'-UTR,CDS,intron-Distal3.664074.94406K562YBX3
chr162959776296018-5'-UTR,intron-Distal,intron-Proximal7.5765330.13844HepG2DDX3X
chr162959156295977-5'-UTR,CDS,intron-Distal6.0801165.02292HepG2DDX3X
chr162935336293548-5'-UTR,CDS,intron-Distal,intron-Proximal4.121203.25175K562YBX3
chr162948606294958-5'-UTR,CDS,intron-Distal,intron-Proximal4.969396.08021K562PRPF8
chr162921706292179-5'-UTR,CDS,intron-Distal3.914673.02850K562YBX3
chr162934606293538-5'-UTR,CDS,intron-Distal,intron-Proximal5.221835.26064K562AQR
chr162949446294956-5'-UTR,CDS,intron-Distal,intron-Proximal4.260203.99162HepG2DDX3X
chr162948696294952-5'-UTR,CDS,intron-Distal,intron-Proximal4.743364.65563K562AQR
chr162949696295017-CDS,intron-Distal3.447159.50106K562DDX3X
chr162957846295915-CDS,intron-Distal6.24684400.00000HepG2DDX3X
chr162949566294976-CDS,intron-Distal4.634716.05264HepG2DDX3X
chr162950176295035-CDS,intron-Distal,intron-Proximal3.352674.32211K562DDX3X
chr162949766295019-CDS,intron-Distal4.923989.60311HepG2DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ICMT is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ICMT is not available on ENCORE database.

  • 91 RBPs can affect the levels of ICMT.  








The Knockdown/knockout RNA-Seq assay for ICMT is not available on ENCORE database.





91 RBPs can affect the gene expression of ICMT :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ICMTENSG00000116237.111887.046201615.548300.224002.685302.08580HepG2ACO1
ICMTENSG00000116237.112355.535101849.911000.348502.242001.75860HepG2AKAP1
ICMTENSG00000116237.11726.932201623.24060-1.1590038.9853036.65860HepG2AKAP8L
ICMTENSG00000116237.111429.057701747.02920-0.289802.179301.64340HepG2BOP1
ICMTENSG00000116237.11592.538401462.42170-1.3034032.9269030.87740HepG2CALR
ICMTENSG00000116237.112509.991301454.238800.7873011.4692010.00030HepG2CIRBP
ICMTENSG00000116237.111026.676901603.85690-0.643607.722206.62050HepG2CPSF6
ICMTENSG00000116237.111237.816801642.50980-0.408103.000802.20120HepG2DDX55
ICMTENSG00000116237.11916.376601344.44390-0.553008.582507.39820HepG2DNAJC21
ICMTENSG00000116237.11941.487401463.43530-0.636306.454105.56990HepG2EIF2S1
ICMTENSG00000116237.111624.733202034.89160-0.324704.470003.44730HepG2EIF4G1
ICMTENSG00000116237.111337.557101949.29640-0.543405.616404.47910HepG2EIF4G2
ICMTENSG00000116237.112787.583202453.463000.184101.930601.40900HepG2ETF1
ICMTENSG00000116237.111058.427201578.78820-0.576907.613406.23360HepG2EWSR1
ICMTENSG00000116237.11695.47070903.79690-0.378003.274201.98950HepG2FAM120A
ICMTENSG00000116237.11716.54990907.66370-0.341102.384301.65340HepG2FUBP3
ICMTENSG00000116237.111419.020401818.06630-0.357502.425901.82230HepG2GPKOW
ICMTENSG00000116237.111320.511401542.46050-0.224102.263801.37450HepG2HDGF
ICMTENSG00000116237.111653.565902192.61170-0.407106.951105.88190HepG2HNRNPF
ICMTENSG00000116237.111397.008801878.88360-0.427508.807607.66970HepG2HNRNPL
ICMTENSG00000116237.111385.806501735.01690-0.324202.309001.72810HepG2HNRNPLL
ICMTENSG00000116237.111732.522402159.09820-0.317603.284202.50120HepG2IGF2BP1
ICMTENSG00000116237.111098.669101531.96350-0.4796010.340309.01470HepG2ILF2
ICMTENSG00000116237.11773.131101476.89000-0.9338030.5442027.74270HepG2KIF1C
ICMTENSG00000116237.11585.72410873.63310-0.576802.843101.94030HepG2PABPC1
ICMTENSG00000116237.111252.965501484.54430-0.244702.491001.68290HepG2PARN
ICMTENSG00000116237.111090.334801337.67400-0.295002.927502.17170HepG2PPIL4
ICMTENSG00000116237.111168.570001430.22100-0.291503.260202.42660HepG2PRPF4
ICMTENSG00000116237.111731.973902071.04490-0.257902.370301.74880HepG2PUM2
ICMTENSG00000116237.111403.594201998.03480-0.509507.671906.34580HepG2RBM15
ICMTENSG00000116237.111760.127302361.95570-0.424304.506903.66400HepG2RPLP0
ICMTENSG00000116237.11967.887101253.12170-0.372602.448701.70450HepG2RRP9
ICMTENSG00000116237.11950.147201335.62220-0.491308.648907.60400HepG2SAFB2
ICMTENSG00000116237.112511.779501960.808100.357201.972001.40100HepG2SF3A3
ICMTENSG00000116237.111612.584601872.04520-0.215202.622401.93730HepG2SLBP
ICMTENSG00000116237.11417.376201614.77860-1.9519035.6231032.36940HepG2SMNDC1
ICMTENSG00000116237.111261.255201910.81080-0.599303.909102.97260HepG2SNRNP70
ICMTENSG00000116237.111696.183602316.12470-0.449409.349808.57850HepG2SRFBP1
ICMTENSG00000116237.112375.568201679.968800.4997010.9181010.11330HepG2SRSF1
ICMTENSG00000116237.112275.581801927.709600.239202.875102.23710HepG2SRSF5
ICMTENSG00000116237.111484.056302154.16290-0.5376011.4445010.19470HepG2SRSF7
ICMTENSG00000116237.111136.211501366.74690-0.266502.981302.41250HepG2SRSF9
ICMTENSG00000116237.111023.782701635.02220-0.675407.104406.10070HepG2SUPV3L1
ICMTENSG00000116237.111984.663401510.030300.394205.525404.78020HepG2TAF15
ICMTENSG00000116237.111914.334601200.406700.673203.039501.92360HepG2TBRG4
ICMTENSG00000116237.111161.104601387.50280-0.257002.040101.31900HepG2TIA1
ICMTENSG00000116237.111123.671201457.40620-0.375204.073503.49190HepG2TIAL1
ICMTENSG00000116237.111119.355501470.32070-0.393505.878705.11080HepG2TRIM56
ICMTENSG00000116237.111447.748201678.87740-0.213702.294101.73790HepG2UTP3
ICMTENSG00000116237.111306.827201609.50220-0.300502.127201.48410HepG2XRN2
ICMTENSG00000116237.111651.136101411.444000.226202.653601.99470HepG2ZC3H8
ICMTENSG00000116237.111664.826001912.49890-0.200102.544202.01380HepG2ZNF622
ICMTENSG00000116237.111166.512401846.47490-0.6626015.5908014.35670K562AGGF1
ICMTENSG00000116237.111549.699402028.82990-0.388703.962802.74270K562AKAP8
ICMTENSG00000116237.11686.266301921.29980-1.4852040.1417037.14150K562AKAP8L
ICMTENSG00000116237.113858.455403062.895200.333003.351501.98110K562APOBEC3C
ICMTENSG00000116237.112045.477002975.82740-0.540902.359901.81140K562AQR
ICMTENSG00000116237.111636.870502015.82840-0.300403.603302.54910K562ATP5C1
ICMTENSG00000116237.111569.417901856.25570-0.242202.555101.63550K562BCLAF1
ICMTENSG00000116237.111287.788801693.34110-0.395003.245402.29890K562BOP1
ICMTENSG00000116237.111511.757501917.85280-0.343303.935302.12030K562CEBPZ
ICMTENSG00000116237.111288.632101800.45110-0.482506.172905.00270K562CPSF6
ICMTENSG00000116237.111770.759602204.40740-0.316004.462302.89900K562DDX21
ICMTENSG00000116237.111242.794901704.64580-0.455904.091702.96470K562EFTUD2
ICMTENSG00000116237.11973.625201180.28130-0.277702.913301.66600K562EIF2S1
ICMTENSG00000116237.111627.116001376.116400.241602.208801.49220K562EIF3G
ICMTENSG00000116237.11887.907301320.49000-0.572605.243303.60090K562FKBP4
ICMTENSG00000116237.111481.033901832.02530-0.306802.333301.54620K562FMR1
ICMTENSG00000116237.111153.269501552.85400-0.429203.556702.50890K562FTO
ICMTENSG00000116237.11903.100701216.61040-0.429904.451802.70090K562FUS
ICMTENSG00000116237.112308.661601167.550500.9835030.8034028.92280K562FXR1
ICMTENSG00000116237.111175.717101718.94280-0.548006.564805.34580K562GPKOW
ICMTENSG00000116237.111623.741202047.41590-0.334503.388402.19600K562HNRNPA1
ICMTENSG00000116237.11969.854101487.92140-0.617502.664601.47530K562HNRNPA2B1
ICMTENSG00000116237.111266.404301521.48120-0.264701.943501.43210K562HNRNPC
ICMTENSG00000116237.112619.392801984.914800.400103.147402.14980K562HNRNPM
ICMTENSG00000116237.111034.249702039.12320-0.9794012.1925010.06260K562KIF1C
ICMTENSG00000116237.11991.144701467.88070-0.566604.134802.97230K562KRR1
ICMTENSG00000116237.111531.616101951.82590-0.349802.992301.86400K562MAK16
ICMTENSG00000116237.111836.856702284.31300-0.314503.203202.21320K562MBNL1
ICMTENSG00000116237.111346.555101677.89890-0.317402.572001.73190K562METAP2
ICMTENSG00000116237.111053.680501601.12530-0.603604.822803.55500K562NAA15
ICMTENSG00000116237.111761.441102428.37390-0.4632012.3091010.89010K562NSUN2
ICMTENSG00000116237.112332.736601841.699700.340903.901902.94410K562POLR2G
ICMTENSG00000116237.111057.982601364.13310-0.366703.198602.21480K562PSIP1
ICMTENSG00000116237.112210.231101513.662900.546108.172607.07370K562PTBP1
ICMTENSG00000116237.114906.772403787.257000.373504.637903.58500K562PUF60
ICMTENSG00000116237.114779.528204027.485200.246903.260702.09860K562PUM1
ICMTENSG00000116237.11877.432501905.69610-1.1190018.9678017.57900K562PUS1
ICMTENSG00000116237.111241.483001856.57020-0.580609.826108.73570K562RBM15
ICMTENSG00000116237.111271.58700784.830100.696106.883205.21510K562RPS3
ICMTENSG00000116237.112105.887601641.069400.359703.591702.35080K562SAFB
ICMTENSG00000116237.112059.071702396.00270-0.218602.128701.40650K562SF3A3
ICMTENSG00000116237.11759.774501469.48260-0.951706.874803.76430K562SMNDC1
ICMTENSG00000116237.111965.605402454.74000-0.320605.934604.63210K562SRPK2
ICMTENSG00000116237.112048.437101483.882600.465005.937104.90990K562SRSF1
ICMTENSG00000116237.111113.905301401.38640-0.331202.522001.52680K562SRSF5
ICMTENSG00000116237.111590.546001967.35380-0.306704.033502.59720K562SRSF7
ICMTENSG00000116237.111152.524901419.49190-0.300602.968701.63610K562SSB
ICMTENSG00000116237.111129.187001606.43870-0.508604.103302.84660K562SUPV3L1
ICMTENSG00000116237.112867.453801847.303800.6342010.923309.29380K562SYNCRIP
ICMTENSG00000116237.111309.637001700.04120-0.376402.774901.75440K562UCHL5
ICMTENSG00000116237.111226.433601931.88000-0.655503.341001.87480K562UTP18
ICMTENSG00000116237.111386.588702203.23080-0.6681011.317609.49350K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ICMT is not available on ENCORE database.





10 RBPs can affect the splicing of ICMT :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEICMTENSG00000116237.11chr1-629446462945716293533629370362949456295034-0.100000.004210.06606excludedK562SRSF1
SEICMTENSG00000116237.11chr1-6294464629457162935336293703629494562950340.209000.000060.00255includedHepG2HNRNPK
SEICMTENSG00000116237.11chr1-6294464629457162935336293703629494562950340.242000.000000.00034includedK562FXR1
SEICMTENSG00000116237.11chr1-629446462945716293533629370362949456295034-0.217000.001210.09187excludedHepG2SRSF7
SEICMTENSG00000116237.11chr1-629353362937036291961629217962949456295034-0.180000.001020.01728excludedK562PUS1
SEICMTENSG00000116237.11chr1-629353362937036291961629217962949456295034-0.218000.000550.01392excludedK562U2AF1
SEICMTENSG00000116237.11chr1-629353362937036291961629217962949456295034-0.160000.006850.09213excludedK562U2AF2
SEICMTENSG00000116237.11chr1-629353362937036291961629217962949456295034-0.131000.001290.04547excludedK562HNRNPU
SEICMTENSG00000116237.11chr1-629353362937036291961629217962949456295034-0.156000.004380.08289excludedK562RBM15
SEICMTENSG00000116237.11chr1-6294464629457162935336293703629494562950340.237000.000000.00063includedK562HNRNPK
SEICMTENSG00000116237.11chr1-6293533629370362919616292179629494562950340.089000.000610.02721includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ICMT is not avaliable on ENCORE database.