FBXL4

General Information

Gene Name       : FBXL4
Gene ID             : ENSG00000112234.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXL4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXL4ENSG00000112234.84.794.264.53ENCSR000AEF
HepG2FBXL4ENSG00000112234.85.437.506.46ENCSR985KAT
K562FBXL4ENSG00000112234.85.135.205.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXL4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXL4 RNA is bound by 17 proteins.  







eCLIP assay for FBXL4 is not avaliable on ENCORE database.





17 proteins are bound to FBXL4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr69932200699322132-3'-UTR,intron-Distal4.025055.01462HepG2FUBP3
chr69937486199374964-5'-UTR,CDS,intron-Distal,intron-Proximal3.351535.58362HepG2U2AF2
chr69939568199395774-5'-UTR,intron-Distal3.400514.10374K562DDX3X
chr69939568099395826-5'-UTR,intron-Distal,intron-Proximal4.201897.12467HepG2DDX3X
chr69939568599395824-5'-UTR,intron-Distal,intron-Proximal3.194654.88807HepG2NCBP2
chr69935333799353447-CDS,intron-Distal3.143115.24980HepG2GRWD1
chr69932840699328478-CDS,intron-Distal,intron-Proximal3.627144.58287K562PRPF8
chr69934707199347197-CDS,intron-Distal,intron-Proximal4.788116.15361K562PRPF8
chr69935350199353554-CDS,intron-Distal,intron-Proximal3.428194.97118HepG2U2AF2
chr69932839499328466-CDS,intron-Distal,intron-Proximal5.557835.01842HepG2PRPF8
chr69932848599328533-CDS,intron-Distal,intron-Proximal4.346094.20763HepG2U2AF2
chr69932227899322334-CDS,intron-Distal3.859094.77518HepG2U2AF2
chr69939472299394765-intron-Distal3.860896.51675HepG2SUGP2
chr69939528399395391-intron-Distal4.553455.57532K562HNRNPM
chr69938137899381430-intron-Distal3.972516.26907HepG2SUGP2
chr69936130699361365-intron-Distal3.376454.56666K562HNRNPM
chr69939512299395170-intron-Distal4.727016.32237HepG2SUGP2
chr69935939899359503-intron-Distal3.586826.79980HepG2SUGP2
chr69939543699395576-intron-Distal3.214506.57022HepG2SUGP2
chr69935506999355182-intron-Distal3.349353.59765K562ILF3
chr69932494699325088-intron-Distal3.976113.80954K562HNRNPL
chr69939489899395007-intron-Distal4.9585014.45079HepG2SUGP2
chr69939519299395279-intron-Distal5.329819.75642HepG2SUGP2
chr69934278499342905-intron-Distal4.616154.12480HepG2HNRNPM
chr69939529499395448-intron-Distal4.432287.67565HepG2HNRNPM
chr69936863999368714-intron-Distal4.146904.13641K562TARDBP
chr69938235799382408-intron-Distal3.434533.59523HepG2SUGP2
chr69939411099394153-intron-Distal4.614046.10726HepG2SUGP2
chr69939558899395646-intron-Distal4.557715.04209K562MATR3
chr69939559799395647-intron-Distal3.639243.68462HepG2MATR3
chr69936784899367905-intron-Distal3.066613.70059HepG2U2AF2
chr69935320799353268-intron-Distal,intron-Proximal3.954684.10688K562KHSRP
chr69932417999324267-intron-Distal3.805263.66668K562KHSRP
chr69938170599381736-intron-Distal4.270023.54208HepG2SUGP2
chr69936758199367684-intron-Distal3.284944.10408K562KHSRP
chr69935939799359443-intron-Distal3.204803.39857HepG2HNRNPM
chr69937318099373232-intron-Distal3.280453.29213HepG2KHSRP
chr69934686799346990-intron-Distal3.910716.41553K562KHSRP
chr69938073399380781-intron-Distal3.506185.08575HepG2SUGP2
chr69936480799364881-intron-Distal3.064334.35941K562KHSRP
chr69936488199364984-intron-Distal4.696295.62025K562KHSRP
chr69939490599394975-intron-Distal4.897455.02084HepG2HNRNPM
chr69936472499364817-intron-Distal4.494775.04993HepG2QKI
chr69935360899353674-intron-Distal,intron-Proximal3.812018.47371K562KHSRP
chr69938109899381163-intron-Distal3.821565.30446HepG2SUGP2
chr69935367499353783-intron-Distal4.8052614.00650K562KHSRP
chr69938194399382010-intron-Distal3.958506.26907HepG2SUGP2
chr69935380299353935-intron-Distal3.336703.61097K562ILF3
chr69939476599394799-intron-Distal4.422025.04879HepG2SUGP2
chr69938162999381677-intron-Distal3.712094.57452HepG2SUGP2
chr69939532399395450-intron-Distal3.386893.77567K562NONO
chr69936508899365173-intron-Distal,intron-Proximal3.394506.39618K562KHSRP
chr69938208499382142-intron-Distal4.861876.88667HepG2SUGP2
chr69939441299394500-intron-Distal3.322673.14895K562NONO
chr69933750499337558-intron-Distal3.471394.41834HepG2HNRNPC
chr69936131399361361-intron-Distal4.375503.89080K562EXOSC5
chr69936177399361807-intron-Distal5.118218.36828K562EXOSC5
chr69935400699354054-intron-Distal3.992343.82619K562ILF3
chr69938116399381193-intron-Distal3.920213.79098HepG2SUGP2
chr69936501799365088-intron-Distal3.808125.32884K562KHSRP
chr69935322799353275-intron-Distal,intron-Proximal4.660115.13577HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXL4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXL4 is not available on ENCORE database.

  • 78 RBPs can affect the levels of FBXL4.  








The Knockdown/knockout RNA-Seq assay for FBXL4 is not available on ENCORE database.





78 RBPs can affect the gene expression of FBXL4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXL4ENSG00000112234.4516.98810695.66030-0.428304.471703.73500HepG2ACO1
FBXL4ENSG00000112234.4639.932501288.02930-1.009209.023708.12490HepG2AKAP1
FBXL4ENSG00000112234.41037.55150698.957200.569808.688707.42650HepG2AKAP8L
FBXL4ENSG00000112234.4856.39380631.121100.440304.019503.11270HepG2CALR
FBXL4ENSG00000112234.4571.52190419.478700.446102.640001.96700HepG2CPSF6
FBXL4ENSG00000112234.4448.15690569.90930-0.346702.446301.49220HepG2YBX3
FBXL4ENSG00000112234.4437.79610643.40190-0.555507.023405.79330HepG2DDX19B
FBXL4ENSG00000112234.4419.31390584.89640-0.480203.380902.63590HepG2DDX21
FBXL4ENSG00000112234.4796.742301233.93670-0.631104.475903.69440HepG2DDX3X
FBXL4ENSG00000112234.4338.40050478.92210-0.501102.007201.33720HepG2DDX55
FBXL4ENSG00000112234.4787.48740476.351300.725103.773102.63850HepG2DDX59
FBXL4ENSG00000112234.4812.997501059.73680-0.382402.111401.56510HepG2DDX6
FBXL4ENSG00000112234.4777.998001018.98920-0.389302.049501.53030HepG2EIF2S1
FBXL4ENSG00000112234.4831.935401126.21820-0.436902.223301.64850HepG2EIF4A3
FBXL4ENSG00000112234.4594.957401096.31130-0.881807.525206.42100HepG2EIF4B
FBXL4ENSG00000112234.4509.878901135.95790-1.1557011.053109.76140HepG2FXR1
FBXL4ENSG00000112234.4672.346501053.95120-0.648504.860303.98950HepG2G3BP1
FBXL4ENSG00000112234.4578.95530840.93620-0.538503.021501.85660HepG2GRSF1
FBXL4ENSG00000112234.4389.11120564.99740-0.538103.527102.80890HepG2HNRNPA1
FBXL4ENSG00000112234.4462.16690628.44160-0.443402.907002.19800HepG2HNRNPC
FBXL4ENSG00000112234.4620.537701066.79230-0.781707.198606.11140HepG2HNRNPK
FBXL4ENSG00000112234.4628.49580453.772400.469802.918102.27420HepG2HNRNPLL
FBXL4ENSG00000112234.4361.77080519.33680-0.521603.988502.86620HepG2HNRNPM
FBXL4ENSG00000112234.4481.93100624.28770-0.373403.181202.53470HepG2HNRNPU
FBXL4ENSG00000112234.4621.15000982.46250-0.661504.875503.26090HepG2HSPD1
FBXL4ENSG00000112234.4718.887301071.38370-0.575603.709802.93770HepG2IGF2BP2
FBXL4ENSG00000112234.4572.15600964.55170-0.753406.148704.90200HepG2LARP4
FBXL4ENSG00000112234.4416.85970597.16970-0.518603.205601.98400HepG2LARP7
FBXL4ENSG00000112234.4682.450101136.35290-0.735606.144605.17430HepG2MAGOH
FBXL4ENSG00000112234.4731.898001142.76980-0.642804.808503.99430HepG2MATR3
FBXL4ENSG00000112234.4693.55550462.832600.583402.867001.87980HepG2MTPAP
FBXL4ENSG00000112234.4631.267101169.73460-0.889906.985006.00030HepG2NCBP2
FBXL4ENSG00000112234.4575.38260784.13590-0.446603.203902.38590HepG2NOL12
FBXL4ENSG00000112234.4597.14830402.370500.569503.926503.04010HepG2NSUN2
FBXL4ENSG00000112234.4493.18500740.38260-0.586103.313202.18040HepG2PCBP2
FBXL4ENSG00000112234.4819.39240569.407900.525006.384205.26260HepG2PRPF4
FBXL4ENSG00000112234.4495.01160778.36740-0.653003.718602.31490HepG2PRPF6
FBXL4ENSG00000112234.4691.955201027.29690-0.570108.277607.43670HepG2PTBP1
FBXL4ENSG00000112234.4542.07640748.46230-0.465402.786802.18840HepG2PUF60
FBXL4ENSG00000112234.4929.967901112.56710-0.258601.966401.42570HepG2QKI
FBXL4ENSG00000112234.4476.89000714.61780-0.583502.638901.95010HepG2RAVER1
FBXL4ENSG00000112234.4404.89500584.71830-0.530202.687201.64480HepG2RCC2
FBXL4ENSG00000112234.4721.676301143.27470-0.6637011.0757010.12940HepG2NELFE
FBXL4ENSG00000112234.4734.838101064.81980-0.535107.563906.61880HepG2RECQL
FBXL4ENSG00000112234.4292.65970418.69330-0.516701.915401.39550HepG2RPS19
FBXL4ENSG00000112234.4457.75500664.13770-0.536902.960502.13450HepG2RPS2
FBXL4ENSG00000112234.4676.62360912.11300-0.430902.307701.57550HepG2RPS3A
FBXL4ENSG00000112234.4411.87770555.96380-0.432803.848003.10940HepG2SAFB2
FBXL4ENSG00000112234.4406.39880844.62380-1.0554010.450309.07700HepG2SF3A3
FBXL4ENSG00000112234.4544.057201069.53120-0.9751021.0579019.67940HepG2SF3B4
FBXL4ENSG00000112234.4390.93070648.36120-0.7299010.811209.67320HepG2SMN1
FBXL4ENSG00000112234.41131.19140499.743801.1785011.351809.78380HepG2SNRNP70
FBXL4ENSG00000112234.4845.28570999.39870-0.241601.976501.53160HepG2SRFBP1
FBXL4ENSG00000112234.4670.223301116.36610-0.7361013.6967012.81660HepG2SRSF1
FBXL4ENSG00000112234.4666.91340840.41840-0.333602.275901.70170HepG2SUCLG1
FBXL4ENSG00000112234.4582.82590442.340700.397802.291001.62180HepG2TARDBP
FBXL4ENSG00000112234.4374.55690606.66310-0.695707.327406.58430HepG2TIAL1
FBXL4ENSG00000112234.4249.11630436.74600-0.810002.855801.83510HepG2UPF2
FBXL4ENSG00000112234.4373.89370723.18270-0.9517014.5295013.31790HepG2UTP3
FBXL4ENSG00000112234.4605.00610823.81520-0.445404.840404.16850HepG2ZNF622
FBXL4ENSG00000112234.4643.62770941.38230-0.548605.148204.39070K562AQR
FBXL4ENSG00000112234.4456.13210577.64320-0.340702.408301.51530K562BCLAF1
FBXL4ENSG00000112234.4421.69000590.31560-0.485303.759202.51990K562DDX3X
FBXL4ENSG00000112234.4775.59750925.51700-0.255002.088201.50940K562DDX47
FBXL4ENSG00000112234.4311.53060491.68050-0.658304.836603.61430K562EFTUD2
FBXL4ENSG00000112234.4344.92140526.42030-0.609903.901402.64720K562EIF3D
FBXL4ENSG00000112234.4314.98400513.27650-0.704506.915405.66850K562EIF3G
FBXL4ENSG00000112234.4433.88460555.43330-0.356302.502901.42440K562EIF4B
FBXL4ENSG00000112234.4628.31550447.823400.488503.140401.92400K562FKBP4
FBXL4ENSG00000112234.4414.30900641.39760-0.630506.856505.96450K562FXR1
FBXL4ENSG00000112234.4846.79570652.722400.375401.891601.31920K562G3BP2
FBXL4ENSG00000112234.4519.29270820.04860-0.659206.910605.70860K562GRSF1
FBXL4ENSG00000112234.4292.22720515.92630-0.820107.575606.63420K562HNRNPC
FBXL4ENSG00000112234.4569.09060836.45060-0.555605.488603.94250K562HNRNPL
FBXL4ENSG00000112234.4278.40540534.00140-0.939704.579803.35710K562HNRNPM
FBXL4ENSG00000112234.4537.51960763.46890-0.506304.355602.78370K562IGF2BP3
FBXL4ENSG00000112234.4369.03570493.87460-0.420402.539001.70390K562METAP2
FBXL4ENSG00000112234.4472.30850644.32110-0.448104.094303.12640K562MTPAP
FBXL4ENSG00000112234.4420.63470615.83990-0.550004.730103.11950K562NCBP2
FBXL4ENSG00000112234.4536.81770737.00960-0.457302.137301.42070K562PPIG
FBXL4ENSG00000112234.4228.02480478.46220-1.0692010.034108.60170K562PRPF8
FBXL4ENSG00000112234.4604.76690766.51090-0.341902.545101.90420K562PTBP1
FBXL4ENSG00000112234.4533.68670735.08760-0.461903.584302.61770K562RBM22
FBXL4ENSG00000112234.4340.60960487.35270-0.516802.852402.02300K562RPS19
FBXL4ENSG00000112234.4444.05480678.92300-0.612506.412405.07240K562SF3B4
FBXL4ENSG00000112234.4487.74290751.41670-0.623506.370605.30950K562SRSF1
FBXL4ENSG00000112234.4515.02260709.60800-0.462403.507002.29980K562SRSF5
FBXL4ENSG00000112234.4520.31210760.52480-0.547604.476803.57160K562TARDBP
FBXL4ENSG00000112234.4527.08880733.60100-0.476904.048103.03060K562TIA1
FBXL4ENSG00000112234.4499.95550719.78100-0.525804.075002.70670K562TRA2A
FBXL4ENSG00000112234.4834.52970653.605400.352402.862102.04540K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXL4 is not available on ENCORE database.





14 RBPs can affect the splicing of FBXL4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXL4ENSG00000112234.4chr6-9932842899328500993232909932360399347143993473570.317000.000900.01930includedK562SRSF1
SEFBXL4ENSG00000112234.4chr6-993652499936559599353301993535469937435299374936-0.244000.006240.08780excludedK562SF3B4
SEFBXL4ENSG00000112234.4chr6-9932842899328500993232909932360399347143993473570.286000.000570.08053includedK562MATR3
SEFBXL4ENSG00000112234.4chr6-993284289932850099323290993236039934714399347357-0.439000.000000.00003excludedK562PUS1
SEFBXL4ENSG00000112234.4chr6-9932842899328500993232909932360399347143993473570.287000.001290.05449includedHepG2SFPQ
SEFBXL4ENSG00000112234.4chr6-9932842899328500993232909932360399347143993473570.158000.000940.04093includedHepG2MATR3
SEFBXL4ENSG00000112234.4chr6-993652499936559599353301993535469937435299374936-0.214000.000820.08430excludedHepG2HNRNPUL1
SEFBXL4ENSG00000112234.4chr6-993284289932850099323290993236039934714399347357-0.389000.000000.00028excludedHepG2SF3A3
SEFBXL4ENSG00000112234.4chr6-993755809937569899374352993749369938263799382755-0.212000.001250.03230excludedK562RBM15
SEFBXL4ENSG00000112234.4chr6-993284289932850099323290993236039934714399347357-0.356000.000330.01128excludedK562RBM15
SEFBXL4ENSG00000112234.4chr6-993284289932850099323290993236039934714399347357-0.424000.000020.00132excludedK562AGGF1
SEFBXL4ENSG00000112234.4chr6-993652499936559599353301993535469937435299374936-0.405000.000540.09995excludedK562SERBP1
SEFBXL4ENSG00000112234.4chr6-993652499936559599353301993535469937435299374936-0.358000.000980.01891excludedK562HNRNPC
MXEFBXL4ENSG00000112234.4chr6-9932329099323603993284289932850099321600993223179934714399347357-0.407000.000200.009432includedK562RBM15
MXEFBXL4ENSG00000112234.4chr6-9932329099323603993284289932850099321600993223179934714399347357-0.403000.000290.007692includedK562PUS1
MXEFBXL4ENSG00000112234.4chr6-9932329099323603993284289932850099321600993223179934714399347357-0.366000.001130.039562includedK562AGGF1
MXEFBXL4ENSG00000112234.4chr6-99323290993236039932842899328500993216009932231799347143993473570.367000.000120.009291includedK562FXR1
MXEFBXL4ENSG00000112234.4chr6-9937435299374936993755809937569899353301993535469938263799382755-0.486000.000350.025912includedK562UTP18
MXEFBXL4ENSG00000112234.4chr6-99328428993285009934714399347357993232909932360399353301993535460.290000.002090.060011includedHepG2SF3A3
MXEFBXL4ENSG00000112234.4chr6-99323290993236039932842899328500993216009932231799347143993473570.353000.007710.043791includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXL4 is not avaliable on ENCORE database.