FAF2

General Information

Gene Name       : FAF2
Gene ID             : ENSG00000113194.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: FAF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAF2ENSG00000113194.1227.4828.3627.92ENCSR000AEF
HepG2FAF2ENSG00000113194.1219.8724.8522.36ENCSR985KAT
K562FAF2ENSG00000113194.1230.2529.2129.73ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAF2 RNA is bound by 22 proteins.  







eCLIP assay for FAF2 is not avaliable on ENCORE database.





22 proteins are bound to FAF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5175934549175934594+3'-UTR3.556734.14964K562UPF1
chr5175934923175934989+3'-UTR4.486235.17229HepG2UPF1
chr5175936622175936675+3'-UTR4.448115.54906K562IGF2BP1
chr5175934596175934669+3'-UTR3.699874.06897HepG2FAM120A
chr5175935046175935103+3'-UTR3.603113.77931K562UPF1
chr5175934353175934421+3'-UTR4.332659.04978K562RBM15
chr5175934329175934414+3'-UTR4.736276.81022K562IGF2BP1
chr5175936752175936817+3'-UTR3.491913.07801K562UPF1
chr5175934160175934253+3'-UTR3.9917710.83603HepG2IGF2BP1
chr5175934578175934674+3'-UTR4.679744.93188HepG2UPF1
chr5175935631175935773+3'-UTR3.927106.21348K562YBX3
chr5175934244175934304+3'-UTR3.234803.34573K562IGF2BP2
chr5175934086175934130+3'-UTR3.337594.01163K562RBM15
chr5175934182175934244+3'-UTR3.853325.99631K562IGF2BP2
chr5175934262175934301+3'-UTR3.267633.77784K562RBM15
chr5175935377175935422+3'-UTR4.376415.40422HepG2IGF2BP1
chr5175936379175936440+3'-UTR3.579874.51666K562RBM15
chr5175934182175934253+3'-UTR3.221533.97768HepG2IGF2BP3
chr5175934683175934739+3'-UTR3.165263.34495K562IGF2BP1
chr5175935320175935378+3'-UTR3.908243.09815K562IGF2BP1
chr5175935280175935361+3'-UTR4.918986.40308HepG2IGF2BP1
chr5175933941175933998+3'-UTR,CDS3.563444.68928K562RBM15
chr5175936184175936257+3'-UTR4.085704.61003HepG2IGF2BP3
chr5175934253175934304+3'-UTR3.278813.85040HepG2IGF2BP1
chr5175936865175936920+3'-UTR3.997343.15006K562RBM15
chr5175935213175935247+3'-UTR4.213144.48843K562TIA1
chr5175875371175875466+5'-UTR,CDS,intron-Distal4.020696.12756HepG2NCBP2
chr5175925926175926018+CDS5.485477.93299HepG2SND1
chr5175906173175906239+CDS,intron-Proximal3.983393.00996K562BUD13
chr5175875445175875515+CDS,intron-Distal,intron-Proximal4.4381814.92191HepG2PRPF8
chr5175906190175906258+CDS,intron-Proximal3.982153.34184HepG2GRWD1
chr5175913355175913446+CDS,intron-Proximal3.197463.79741HepG2GRWD1
chr5175933830175933885+CDS3.293863.46049K562RBM15
chr5175927001175927091+CDS,intron-Proximal3.813525.85226K562UCHL5
chr5175921074175921154+CDS,intron-Proximal3.176913.49653K562PRPF8
chr5175916020175916070+CDS,intron-Proximal3.378393.18246K562PRPF8
chr5175913391175913450+CDS3.474094.30677K562YBX3
chr5175923499175923605+CDS4.563383.48040HepG2SND1
chr5175919178175919275+CDS,intron-Proximal3.346616.96989HepG2U2AF2
chr5175913450175913491+CDS,intron-Proximal4.099693.89948K562YBX3
chr5175923623175923689+CDS,intron-Proximal4.354964.67689HepG2PPIG
chr5175925993175926088+CDS,intron-Proximal4.683586.15968K562UCHL5
chr5175921001175921050+CDS4.744665.24633HepG2SND1
chr5175915938175915999+CDS,intron-Proximal4.174113.77802HepG2U2AF2
chr5175916076175916136+intron-Distal,intron-Proximal4.045393.12843K562PRPF8
chr5175921276175921432+intron-Distal,intron-Proximal3.292263.93901K562KHSRP
chr5175879072175879130+intron-Distal3.655683.24242HepG2HNRNPC
chr5175885070175885137+intron-Distal4.1490316.35021K562PTBP1
chr5175885068175885132+intron-Distal4.154033.90241K562MATR3
chr5175885046175885134+intron-Distal4.8214012.24240HepG2PTBP1
chr5175875580175875668+intron-Distal3.454313.59783HepG2HNRNPK
chr5175926086175926173+intron-Proximal5.172066.75320K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAF2 is not available on ENCORE database.

  • 86 RBPs can affect the levels of FAF2.  








The Knockdown/knockout RNA-Seq assay for FAF2 is not available on ENCORE database.





86 RBPs can affect the gene expression of FAF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAF2ENSG00000113194.81639.287201381.544800.246702.928402.30530HepG2ACO1
FAF2ENSG00000113194.81544.515102003.57480-0.375405.701104.77600HepG2AUH
FAF2ENSG00000113194.81232.963301503.71870-0.286402.459701.72940HepG2CALR
FAF2ENSG00000113194.8911.636901470.33240-0.689607.721906.48090HepG2CIRBP
FAF2ENSG00000113194.81974.894901381.287500.5157012.4886011.28150HepG2CKAP4
FAF2ENSG00000113194.81792.250201470.258000.285602.370301.34830HepG2CPSF7
FAF2ENSG00000113194.82143.815001806.316100.247002.831602.18220HepG2CELF1
FAF2ENSG00000113194.81512.638001942.15790-0.360606.584105.51040HepG2DAZAP1
FAF2ENSG00000113194.82013.466301539.036800.387602.653602.04920HepG2DDX6
FAF2ENSG00000113194.81165.253401332.23480-0.193201.959901.39320HepG2DNAJC2
FAF2ENSG00000113194.81818.246701479.616100.297201.926801.42190HepG2EIF2S1
FAF2ENSG00000113194.82093.214601635.199400.356202.345501.75520HepG2EIF4A3
FAF2ENSG00000113194.81235.442101592.00130-0.365801.881501.30640HepG2EIF4B
FAF2ENSG00000113194.81484.920001835.51150-0.305802.226801.49080HepG2EIF4G2
FAF2ENSG00000113194.81698.745401350.054300.331403.024102.15340HepG2EWSR1
FAF2ENSG00000113194.82347.393001802.683500.380802.706801.94610HepG2FIP1L1
FAF2ENSG00000113194.81922.233101530.415300.328802.154801.56500HepG2G3BP1
FAF2ENSG00000113194.81646.352201248.545900.398903.103802.02340HepG2GNB2L1
FAF2ENSG00000113194.8873.750101225.52270-0.488102.775401.66130HepG2GRSF1
FAF2ENSG00000113194.8834.537101319.00590-0.6604013.6105011.70190HepG2HDGF
FAF2ENSG00000113194.8843.912901356.87610-0.685109.038207.96860HepG2HNRNPA1
FAF2ENSG00000113194.81132.524401509.30820-0.414303.784802.98450HepG2HNRNPC
FAF2ENSG00000113194.81457.055501769.13440-0.280004.107003.29810HepG2HNRNPL
FAF2ENSG00000113194.81151.771301499.32700-0.380505.544904.71010HepG2HNRNPU
FAF2ENSG00000113194.81986.856201555.661800.352902.667002.00260HepG2IGF2BP2
FAF2ENSG00000113194.81503.506001033.360500.540902.936701.85190HepG2METAP2
FAF2ENSG00000113194.81821.690501459.033500.320202.914902.08600HepG2MSI2
FAF2ENSG00000113194.82034.356501210.042700.749404.973303.75490HepG2PABPC1
FAF2ENSG00000113194.81915.485001592.136900.266603.166302.52510HepG2PCBP1
FAF2ENSG00000113194.82119.203001573.869200.429102.363501.40080HepG2PCBP2
FAF2ENSG00000113194.82928.787001518.860600.947207.109406.00750HepG2RAVER1
FAF2ENSG00000113194.82650.665701922.644900.463208.490807.69910HepG2RBM22
FAF2ENSG00000113194.82025.653701592.384000.347103.376402.63740HepG2RBM25
FAF2ENSG00000113194.8801.334801197.84400-0.580005.372303.88680HepG2RCC2
FAF2ENSG00000113194.81584.849401802.96110-0.186001.771601.31810HepG2NELFE
FAF2ENSG00000113194.81181.28870960.787600.298002.242401.68330HepG2RPS19
FAF2ENSG00000113194.81438.222101019.879100.495804.098403.16320HepG2RRP9
FAF2ENSG00000113194.82724.958601868.415000.544303.864503.06140HepG2SF3A3
FAF2ENSG00000113194.81936.885901508.237300.360803.081002.33700HepG2SF3B1
FAF2ENSG00000113194.81346.886201557.03090-0.209202.363701.76300HepG2SMN1
FAF2ENSG00000113194.82468.159201678.178500.556403.558402.66810HepG2SNRNP70
FAF2ENSG00000113194.83149.626002171.580400.5363015.1757014.25160HepG2SRFBP1
FAF2ENSG00000113194.82303.976101815.188700.343905.525304.68470HepG2SRSF5
FAF2ENSG00000113194.81615.534801891.01000-0.227102.269201.63330HepG2SRSF7
FAF2ENSG00000113194.82102.807901432.274200.5539013.0031011.96380HepG2SRSF9
FAF2ENSG00000113194.81509.802701217.309200.310602.665801.74080HepG2SUPT6H
FAF2ENSG00000113194.81907.064401330.239400.519604.733003.88470HepG2SUPV3L1
FAF2ENSG00000113194.8985.994601582.37910-0.6824013.4283012.33000HepG2TAF15
FAF2ENSG00000113194.81062.550901485.21160-0.483104.671303.76270HepG2TARDBP
FAF2ENSG00000113194.81135.346701456.74730-0.359603.768203.20380HepG2TIAL1
FAF2ENSG00000113194.8853.723401218.24920-0.513002.640301.66030HepG2UPF2
FAF2ENSG00000113194.81062.314401703.16980-0.6810014.7278012.58050HepG2UTP18
FAF2ENSG00000113194.82335.643001599.767500.5459012.9742011.81900HepG2UTP3
FAF2ENSG00000113194.8899.985001309.47300-0.541004.332303.43040HepG2XRN2
FAF2ENSG00000113194.82053.530701822.381500.172202.061001.57020HepG2ZNF622
FAF2ENSG00000113194.81811.702102250.33550-0.312804.578003.87970K562AGGF1
FAF2ENSG00000113194.81856.015302341.55650-0.335303.046102.36020K562AKAP8L
FAF2ENSG00000113194.84929.867102548.182500.9520020.6286019.19960K562AQR
FAF2ENSG00000113194.81185.443301406.82800-0.247002.713801.76150K562BCLAF1
FAF2ENSG00000113194.81350.409401722.20480-0.350902.641401.78950K562BOP1
FAF2ENSG00000113194.81325.006901772.36370-0.419704.020502.46260K562CIRBP
FAF2ENSG00000113194.81519.719501831.16920-0.269002.283801.56430K562CPSF6
FAF2ENSG00000113194.8838.301201067.28900-0.348402.450801.46480K562CSTF2
FAF2ENSG00000113194.83206.637803953.55080-0.302103.191302.14620K562CELF1
FAF2ENSG00000113194.83158.019102586.417300.288004.259503.47480K562DDX47
FAF2ENSG00000113194.8823.736301305.68480-0.664606.594004.07580K562DDX51
FAF2ENSG00000113194.81610.587201209.050900.413603.596402.54500K562EFTUD2
FAF2ENSG00000113194.81770.132601294.631500.451202.722701.69620K562EIF3D
FAF2ENSG00000113194.81680.335901378.732200.285302.599601.82630K562EIF3G
FAF2ENSG00000113194.82049.952101208.031900.7628012.3771010.59950K562EIF4A3
FAF2ENSG00000113194.82115.497801256.302100.7517018.5779017.11840K562FXR1
FAF2ENSG00000113194.81666.282901308.956700.348101.886501.31510K562G3BP2
FAF2ENSG00000113194.82044.156802702.47980-0.402804.608103.63390K562GRSF1
FAF2ENSG00000113194.81225.259001659.51650-0.437705.002203.57450K562HNRNPA1
FAF2ENSG00000113194.81422.436701837.75960-0.369604.635103.47360K562HNRNPU
FAF2ENSG00000113194.82091.066201737.955500.266702.288701.51980K562MAGOH
FAF2ENSG00000113194.81641.241901922.90330-0.228502.707701.90750K562MTPAP
FAF2ENSG00000113194.81623.608301206.294200.428505.056603.38990K562NCBP2
FAF2ENSG00000113194.81740.336502136.64470-0.296004.208703.30960K562NSUN2
FAF2ENSG00000113194.82263.999101546.395100.549907.108505.51500K562PCBP2
FAF2ENSG00000113194.82065.119101677.947200.299403.044402.20320K562POLR2G
FAF2ENSG00000113194.81952.903502365.32330-0.276402.060501.35590K562PPIG
FAF2ENSG00000113194.82138.971801176.543000.8623013.8459012.15860K562PRPF8
FAF2ENSG00000113194.84678.866603508.837800.415105.093403.98900K562PUF60
FAF2ENSG00000113194.81544.234002322.32220-0.588707.638506.78280K562PUS1
FAF2ENSG00000113194.81836.808501198.517200.615906.070104.85560K562RPS19
FAF2ENSG00000113194.81696.874801309.650600.373602.863201.84240K562RPS3
FAF2ENSG00000113194.81971.295301361.165500.534208.096906.59090K562SF3B4
FAF2ENSG00000113194.82043.414701655.279200.303802.860502.14380K562SRSF1
FAF2ENSG00000113194.82082.642401682.956200.307303.186502.30550K562SYNCRIP
FAF2ENSG00000113194.8926.057901177.69230-0.346802.171001.35190K562TIAL1
FAF2ENSG00000113194.81617.881401268.895200.350402.281501.30170K562U2AF1
FAF2ENSG00000113194.82073.398601310.462900.6618012.0128010.31960K562U2AF2
FAF2ENSG00000113194.81624.537401938.54990-0.254902.112401.34880K562WDR3
FAF2ENSG00000113194.82466.805702015.754700.291204.667003.59060K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAF2 is not available on ENCORE database.





5 RBPs can affect the splicing of FAF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAF2ENSG00000113194.8chr5+175923486175923664175921184175921276175925914175926086-0.148000.000000.00000excludedK562AQR
SEFAF2ENSG00000113194.8chr5+175915951175916028175913355175913490175919194175919333-0.062000.000300.00627excludedK562PUS1
SEFAF2ENSG00000113194.8chr5+175921184175921276175920999175921085175923486175923664-0.063000.004690.07742excludedK562U2AF1
SEFAF2ENSG00000113194.8chr5+175921184175921276175920999175921085175923486175923664-0.060000.006110.08456excludedK562U2AF2
A3SSFAF2ENSG00000113194.8chr5+1759191551759193331759191941759193331759159091759160280.083000.000290.00229longerK562AQR
MXEFAF2ENSG00000113194.8chr5+1759211841759212761759234301759236641759209991759210851759259141759260860.124000.000490.004911includedK562AQR
MXEFAF2ENSG00000113194.8chr5+1759211841759212761759234861759236641759209991759210851759259141759260860.120000.000700.006681includedK562AQR
MXEFAF2ENSG00000113194.8chr5+1759211841759212761759234861759236641759209991759210851759259141759260860.104000.000010.000491includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAF2 is not avaliable on ENCORE database.