COX19

General Information

Gene Name       : COX19
Gene ID             : ENSG00000240230.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: COX19)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COX19ENSG00000240230.54.398.466.43ENCSR000AEF
HepG2COX19ENSG00000240230.513.7312.9013.32ENCSR985KAT
K562COX19ENSG00000240230.54.384.044.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COX19 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COX19 RNA is bound by 21 proteins.  







eCLIP assay for COX19 is not avaliable on ENCORE database.





21 proteins are bound to COX19 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr710064481006477-3'-UTR,intron-Distal4.543984.75882K562SLTM
chr710079461008063-3'-UTR,intron-Distal5.469857.72954K562SLTM
chr710064411006512-3'-UTR,intron-Distal4.335327.32953HepG2SLTM
chr710077411007790-3'-UTR,intron-Distal3.291683.65070K562SLTM
chr710062981006384-3'-UTR,intron-Distal4.375814.11400K562YWHAG
chr7938430938553-3'-UTR,intron-Distal,intron-Proximal4.232274.40113HepG2AKAP1
chr710056411005715-3'-UTR,intron-Distal,intron-Proximal3.588523.23847HepG2CSTF2
chr710062741006376-3'-UTR,intron-Distal4.2854411.46614K562SLTM
chr710079561008067-3'-UTR,intron-Distal3.856566.61872HepG2SLTM
chr7938428938562-3'-UTR,CDS,intron-Distal,intron-Proximal5.189028.73200HepG2UPF1
chr710149901015151-5'-UTR,CDS,intron-Distal3.071674.14491HepG2NCBP2
chr710150031015074-CDS,intron-Distal4.653074.65563K562AQR
chr710127561012843-CDS,intron-Distal,intron-Proximal3.123453.13705K562BUD13
chr7966263966333-5'-UTR,CDS,intron-Distal,intron-Proximal4.148278.21012HepG2SF3B4
chr710090211009094-CDS,intron-Distal4.364644.23351K562BUD13
chr710127871012880-CDS,intron-Distal,intron-Proximal3.978278.94445HepG2BCLAF1
chr710090821009140-CDS,intron-Distal6.2999745.92785HepG2SF3B4
chr7958067958104-intron-Distal4.104623.40229HepG2CSTF2T
chr7993900993995-intron-Distal4.551295.44474HepG2FAM120A
chr7992695992735-intron-Distal3.678595.56645HepG2CSTF2T
chr7985656985720-intron-Distal4.528776.08348HepG2CSTF2T
chr7953680953717-intron-Distal3.937413.44758HepG2CSTF2T
chr7960778960833-intron-Distal3.482214.84557HepG2CSTF2T
chr7987539987628-intron-Distal5.037737.22168HepG2FAM120A
chr7956550956630-intron-Distal4.297043.97974HepG2RBFOX2
chr7985917986003-intron-Distal4.7984714.35754HepG2CSTF2T
chr7946947946974-intron-Distal3.797603.16310HepG2CSTF2T
chr7994150994293-5'-UTR,intron-Distal4.387683.95192HepG2UPF1
chr7940529940591-CDS,intron-Distal,intron-Proximal4.040313.94684HepG2CSTF2T
chr7966046966126-intron-Distal,intron-Proximal4.039596.48652HepG2CSTF2T
chr7951703951737-intron-Distal4.105934.36133HepG2CSTF2T
chr7993613993666-intron-Distal3.694375.62912HepG2CSTF2T
chr7959999960082-intron-Distal4.387884.36133HepG2CSTF2T
chr7959909959999-intron-Distal4.782415.84605HepG2CSTF2T
chr7949531949600-intron-Distal4.104958.19675HepG2CSTF2T
chr7950101950168-intron-Distal3.878995.08839HepG2CSTF2T
chr7950818950872-intron-Distal4.534564.92128HepG2CSTF2T
chr7987678987762-intron-Distal5.125376.62861HepG2FAM120A
chr7954917954976-intron-Distal3.214635.82968HepG2CSTF2T
chr710149481015019-intron-Distal5.996908.88193HepG2EFTUD2
chr7964834964884-intron-Distal4.185064.19345HepG2CSTF2T
chr7941184941263-intron-Distal4.234833.63902HepG2CSTF2T
chr7959159959264-intron-Distal4.875786.36200HepG2PTBP1
chr7952249952285-intron-Distal3.866353.19526HepG2CSTF2T
chr7964607964657-intron-Distal4.194374.36133HepG2CSTF2T
chr7956225956277-intron-Distal3.636635.62912HepG2CSTF2T
chr710114561011510-intron-Distal3.163393.70732HepG2HNRNPC
chr7946537946604-intron-Distal3.472844.37279HepG2CSTF2T
chr710090941009139-intron-Distal5.022643.91589K562SF3B4
chr7963519963598-intron-Distal4.590085.11753HepG2CSTF2T
chr7948260948316-intron-Distal4.527315.93727HepG2CSTF2T
chr7985475985524-intron-Distal,intron-Proximal4.716576.32277HepG2CSTF2T
chr7960623960688-intron-Distal,intron-Proximal3.474413.48399HepG2CSTF2T
chr7974240974324-intron-Distal4.544594.86859HepG2CSTF2T
chr7949600949632-intron-Distal3.043173.23466HepG2CSTF2T
chr7958305958351-intron-Distal3.429114.37279HepG2CSTF2T
chr7954626954681-intron-Distal4.647825.93727HepG2CSTF2T
chr7950897950946-intron-Distal3.890537.10319HepG2CSTF2T
chr7943591943716-intron-Distal,intron-Proximal5.033165.74291HepG2FAM120A
chr7947170947227-intron-Distal3.790555.39685HepG2CSTF2T
chr7993913993981-intron-Distal5.026588.98373HepG2CSTF2T
chr7963293963345-intron-Distal4.217134.10339HepG2CSTF2T
chr7947842947880-intron-Distal4.810015.22630HepG2SLTM
chr7964542964595-intron-Distal4.104623.40229HepG2CSTF2T
chr7963194963246-intron-Distal4.176823.94684HepG2CSTF2T
chr7943518943591-intron-Distal,intron-Proximal3.148464.20198HepG2FAM120A
chr7986086986134-intron-Distal4.795096.84460HepG2CSTF2T
chr7988007988067-intron-Distal3.812476.03429HepG2CSTF2T
chr7992789992837-intron-Distal3.873157.10319HepG2CSTF2T
chr7958185958267-intron-Distal4.177418.42985HepG2CSTF2T
chr7986047986086-intron-Distal3.545304.60046HepG2CSTF2T
chr7962084962133-intron-Distal3.125273.00221HepG2CSTF2T
chr7938228938338-3'-UTR,intron-Distal,intron-Proximal4.4496812.42188HepG2UPF1
chr7943535943611-intron-Distal,intron-Proximal3.797605.32871HepG2CSTF2T
chr7958381958426-intron-Distal3.613735.39685HepG2CSTF2T
chr7959312959417-intron-Distal5.132425.14122HepG2PCBP2
chr7943577943682-intron-Distal,intron-Proximal4.074537.07105HepG2RBFOX2
chr7993190993258-intron-Distal5.055188.29600HepG2CSTF2T
chr7959139959210-intron-Distal5.370709.55779HepG2PCBP2
chr7958941959042-intron-Distal3.191763.73413HepG2RBFOX2
chr7944939945012-intron-Distal5.096956.23953HepG2PCBP2
chr7956478956541-intron-Distal4.172078.29908HepG2CSTF2T
chr710126641012737-intron-Distal,intron-Proximal3.627144.58287K562PRPF8
chr7992028992062-intron-Distal3.332794.37279HepG2CSTF2T
chr7955169955231-intron-Distal5.335659.35257HepG2CSTF2T
chr7941027941104-intron-Distal,intron-Proximal4.506624.86859HepG2CSTF2T
chr7946668946731-intron-Distal4.482215.84605HepG2CSTF2T
chr7941303941399-intron-Distal5.245254.57154HepG2FAM120A
chr7991627991670-intron-Distal4.090083.16310HepG2CSTF2T
chr7949134949179-intron-Distal4.528776.08348HepG2CSTF2T
chr7952176952211-intron-Distal4.136634.36133HepG2CSTF2T
chr7993087993140-intron-Distal3.740276.03429HepG2CSTF2T
chr7955438955481-intron-Distal3.482214.84557HepG2CSTF2T
chr7944956945060-intron-Distal4.875784.78106HepG2PTBP1
chr7951846951911-intron-Distal3.678595.86001HepG2CSTF2T
chr7961158961207-intron-Distal3.166083.72734HepG2CSTF2T
chr7951950952031-intron-Distal3.731918.97207HepG2CSTF2T
chr7949437949503-intron-Distal3.324266.51348HepG2CSTF2T
chr7958976959026-intron-Distal4.993757.19649HepG2CSTF2T
chr7938226938322-3'-UTR,intron-Distal,intron-Proximal5.178817.53166HepG2AKAP1
chr7985856985900-intron-Distal4.090083.16310HepG2CSTF2T
chr7944831944939-intron-Distal,intron-Proximal5.1539516.60175HepG2PCBP2
chr7987090987173-intron-Distal4.059388.19675HepG2CSTF2T
chr7950322950381-intron-Distal4.075238.42985HepG2CSTF2T
chr7953857953945-intron-Distal3.251046.89356HepG2CSTF2T
chr7941187941278-intron-Distal3.384473.43220HepG2FAM120A
chr7965767965838-intron-Distal4.780367.35173HepG2CSTF2T
chr7944864944946-intron-Distal,intron-Proximal4.293133.89149HepG2HNRNPK
chr7988897988956-intron-Distal3.866353.16310HepG2CSTF2T
chr7948015948107-intron-Distal3.595594.56970HepG2SLTM
chr7963799963919-intron-Distal4.558923.70291HepG2FAM120A
chr7958122958161-intron-Distal4.189733.63902HepG2CSTF2T
chr7958801958890-intron-Distal4.245418.80803HepG2CSTF2T
chr7956069956114-intron-Distal3.008454.51156HepG2CSTF2T
chr7987087987165-intron-Distal4.727446.33281HepG2FAM120A
chr7958896958934-intron-Distal4.505876.08348HepG2CSTF2T
chr7950612950667-intron-Distal4.4775410.62681HepG2CSTF2T
chr7958643958692-intron-Distal3.212635.68177HepG2CSTF2T
chr7962961963065-intron-Distal,intron-Proximal4.765335.11753HepG2CSTF2T
chr7947162947223-intron-Distal5.303116.97212HepG2SLTM
chr7957454957522-intron-Distal3.656676.51348HepG2CSTF2T
chr7981874981969-intron-Distal5.004176.17200HepG2PCBP2
chr7970686970795-intron-Distal5.1472916.04432HepG2PCBP2
chr7985319985383-intron-Distal4.986857.09999HepG2CSTF2T
chr7950844951022-intron-Distal3.294263.48042HepG2NKRF
chr7955106955154-intron-Distal3.189733.04847HepG2CSTF2T
chr7943320943404-intron-Distal3.995603.45219HepG2RBFOX2
chr7948467948640-intron-Distal4.6389812.81546HepG2CSTF2T
chr7957318957367-intron-Distal3.552373.92299HepG2CSTF2T
chr7954852954901-intron-Distal3.445624.14880HepG2CSTF2T
chr7992204992275-intron-Distal3.774695.08839HepG2CSTF2T
chr7946286946355-intron-Distal3.973553.41442HepG2HNRNPK
chr7966365966447-intron-Distal,intron-Proximal3.739465.09328HepG2SF3B4
chr7993742993790-intron-Distal3.466534.14880HepG2CSTF2T
chr7964437964481-intron-Distal4.302594.92128HepG2CSTF2T
chr7974324974397-intron-Distal3.871793.44758HepG2CSTF2T
chr7959299959390-intron-Distal4.346453.23168HepG2DDX59
chr7970635970686-intron-Distal4.895156.97910HepG2PCBP2
chr710149551015039-intron-Distal4.193859.15724HepG2BUD13
chr7988244988291-intron-Distal4.327044.61649HepG2CSTF2T
chr7985535985588-intron-Distal,intron-Proximal3.799106.61028HepG2CSTF2T
chr7987456987523-intron-Distal4.502865.60609HepG2CSTF2T
chr7987413987525-intron-Distal3.988524.88931HepG2FAM120A
chr7956393956447-intron-Distal4.565625.67757HepG2CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COX19 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COX19 is not available on ENCORE database.

  • 90 RBPs can affect the levels of COX19.  








The Knockdown/knockout RNA-Seq assay for COX19 is not available on ENCORE database.





90 RBPs can affect the gene expression of COX19 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COX19ENSG00000240230.1468.90950645.64330-0.461402.807201.85860HepG2ABCF1
COX19ENSG00000240230.1388.27410591.69920-0.607807.166906.28270HepG2ACO1
COX19ENSG00000240230.1323.68880750.26040-1.2128013.1572012.08580HepG2AKAP1
COX19ENSG00000240230.1522.70520776.40820-0.570804.075902.81780HepG2AKAP8
COX19ENSG00000240230.1406.06030594.49690-0.550005.764504.69370HepG2AKAP8L
COX19ENSG00000240230.1650.32600882.42690-0.440303.738502.96240HepG2AUH
COX19ENSG00000240230.1301.50410455.57520-0.595504.063203.35400HepG2BOP1
COX19ENSG00000240230.1371.70940489.87070-0.398202.436201.70920HepG2CALR
COX19ENSG00000240230.1516.67830717.97890-0.474702.564601.63150HepG2CCAR1
COX19ENSG00000240230.1415.92900591.59200-0.508305.500504.62220HepG2CKAP4
COX19ENSG00000240230.1364.70290658.31530-0.852105.409404.33650HepG2CNOT7
COX19ENSG00000240230.1590.46510388.309500.604506.076204.56430HepG2YBX3
COX19ENSG00000240230.1346.74420718.67770-1.0515011.5825010.38290HepG2DDX3X
COX19ENSG00000240230.1450.81140609.31700-0.434702.466701.59420HepG2EEF2
COX19ENSG00000240230.1371.97770507.93610-0.449402.610601.53070HepG2EFTUD2
COX19ENSG00000240230.1294.13710494.61710-0.749805.766504.49600HepG2EIF3D
COX19ENSG00000240230.11225.458701013.140300.274402.649402.05840HepG2ETF1
COX19ENSG00000240230.1329.73700442.08970-0.423002.696401.54620HepG2FAM120A
COX19ENSG00000240230.1468.07240651.91710-0.478003.098702.28850HepG2FIP1L1
COX19ENSG00000240230.1252.68120440.38890-0.801505.797704.49760HepG2GEMIN5
COX19ENSG00000240230.1558.69300384.927900.537403.792803.05380HepG2HNRNPA1
COX19ENSG00000240230.1726.41010480.094000.597407.789906.66520HepG2HNRNPF
COX19ENSG00000240230.1881.61730728.797600.274502.386301.75470HepG2HNRNPL
COX19ENSG00000240230.1295.89420449.71820-0.603904.728703.52290HepG2HNRNPM
COX19ENSG00000240230.1343.10980425.33740-0.309901.800101.30180HepG2HNRNPU
COX19ENSG00000240230.1653.63850472.758100.467304.036003.17580HepG2IGF2BP1
COX19ENSG00000240230.1914.30100662.007100.465703.232402.52380HepG2MAGOH
COX19ENSG00000240230.1405.91290665.70400-0.713705.317504.46750HepG2MATR3
COX19ENSG00000240230.1351.14770527.49730-0.587104.698303.66540HepG2MSI2
COX19ENSG00000240230.1702.14720401.174800.807407.776006.56520HepG2NSUN2
COX19ENSG00000240230.1590.75820379.365700.638906.977105.84650HepG2PPIL4
COX19ENSG00000240230.1417.18650577.74390-0.469704.181303.53910HepG2PTBP1
COX19ENSG00000240230.1506.00520757.45730-0.582004.108803.39880HepG2PUF60
COX19ENSG00000240230.1527.19230804.14630-0.609104.468803.75450HepG2PUM1
COX19ENSG00000240230.1580.65910803.51420-0.468602.031701.45060HepG2PUM2
COX19ENSG00000240230.1409.09710602.68710-0.559006.333905.47040HepG2PUS1
COX19ENSG00000240230.1379.20220846.79860-1.1591022.1806020.99660HepG2RBM22
COX19ENSG00000240230.1736.53760567.873300.375102.654901.99210HepG2RBM25
COX19ENSG00000240230.1530.63460642.97380-0.277001.794201.33850HepG2NELFE
COX19ENSG00000240230.1798.80520598.842100.415604.075303.34530HepG2RECQL
COX19ENSG00000240230.11152.78750517.140101.1564020.5074018.99520HepG2RPLP0
COX19ENSG00000240230.1350.99620520.80020-0.569303.382502.49860HepG2RPS2
COX19ENSG00000240230.1362.18100483.03550-0.415402.299101.43880HepG2SERBP1
COX19ENSG00000240230.1796.75090601.506700.405403.802303.12710HepG2SF3B4
COX19ENSG00000240230.1361.25340504.15590-0.480902.365801.48620HepG2SMNDC1
COX19ENSG00000240230.1623.24990956.42930-0.617809.563108.78470HepG2SRFBP1
COX19ENSG00000240230.1503.42130627.84240-0.318602.165501.73300HepG2SRSF1
COX19ENSG00000240230.1456.12710747.96500-0.713505.461804.62600HepG2SRSF5
COX19ENSG00000240230.1636.14530471.667500.431504.237203.40320HepG2SRSF7
COX19ENSG00000240230.1653.03370830.40960-0.346703.323502.77280HepG2SSB
COX19ENSG00000240230.1577.84700850.56840-0.557703.806003.09750HepG2SUCLG1
COX19ENSG00000240230.1770.14860564.328500.448504.289703.61490HepG2TAF15
COX19ENSG00000240230.1757.05300518.541800.545805.493404.32690HepG2TIA1
COX19ENSG00000240230.1294.26840201.659400.545102.414601.70460HepG2UCHL5
COX19ENSG00000240230.1436.15750628.97270-0.528105.632804.69210HepG2UPF1
COX19ENSG00000240230.1580.41800312.535400.893005.538504.08580HepG2UPF2
COX19ENSG00000240230.1520.63030646.48430-0.312402.271901.30920HepG2UTP18
COX19ENSG00000240230.1583.62590336.086700.796105.298104.30250HepG2XRN2
COX19ENSG00000240230.1413.56840547.59710-0.405003.514702.77150HepG2ZC3H8
COX19ENSG00000240230.1521.65510691.74740-0.407104.349403.70470HepG2ZNF622
COX19ENSG00000240230.1322.85530546.88950-0.760408.640807.71160K562AGGF1
COX19ENSG00000240230.1283.68480569.05280-1.004309.358208.07370K562AKAP8L
COX19ENSG00000240230.11092.32610475.538701.1997019.7639018.36470K562AQR
COX19ENSG00000240230.1470.22640597.05360-0.344502.528001.65690K562ATP5C1
COX19ENSG00000240230.1435.59660668.23140-0.617402.804701.73330K562CNOT7
COX19ENSG00000240230.11153.79160521.241701.1463030.5296028.59680K562DDX47
COX19ENSG00000240230.1472.19730612.40730-0.375103.073402.14340K562DKC1
COX19ENSG00000240230.1520.06470402.025000.371302.551601.85570K562EIF2S2
COX19ENSG00000240230.1386.90400177.263501.126002.530401.57200K562EIF3A
COX19ENSG00000240230.1388.08690209.279700.890807.719006.39500K562EIF3G
COX19ENSG00000240230.1441.60340210.093101.0716011.008009.34790K562EIF4A3
COX19ENSG00000240230.1430.64370324.035500.410202.094501.34500K562FMR1
COX19ENSG00000240230.1356.83710218.485600.707605.346404.54340K562FXR1
COX19ENSG00000240230.1401.04010304.111700.399002.005501.32630K562GPKOW
COX19ENSG00000240230.1690.32400535.709100.365702.341501.64370K562GRSF1
COX19ENSG00000240230.1443.48820255.397900.796006.531305.65280K562HNRNPC
COX19ENSG00000240230.1751.87220458.495800.713506.924705.67580K562HSPD1
COX19ENSG00000240230.1401.90680603.94400-0.587604.936803.77470K562KIF1C
COX19ENSG00000240230.1480.23290267.499100.844108.379506.88090K562MAGOH
COX19ENSG00000240230.1457.37430676.56470-0.564905.180503.85560K562MBNL1
COX19ENSG00000240230.1822.12300621.732900.403002.783201.65100K562MSI2
COX19ENSG00000240230.1481.11830354.719600.439603.506102.60010K562MTPAP
COX19ENSG00000240230.1317.95030474.21960-0.576802.968702.04970K562NAA15
COX19ENSG00000240230.1309.46350209.809600.560603.097301.79760K562NCBP2
COX19ENSG00000240230.1905.36690638.042200.504804.141602.29660K562NOL12
COX19ENSG00000240230.1796.39430599.358700.410003.118901.59600K562PNPT1
COX19ENSG00000240230.1350.26390222.633100.653703.588002.73280K562PRPF8
COX19ENSG00000240230.1394.61850259.886200.602504.511003.68320K562PTBP1
COX19ENSG00000240230.11050.64850636.418400.723107.506106.16020K562PUF60
COX19ENSG00000240230.1908.35890676.960100.424103.640802.40690K562PUM1
COX19ENSG00000240230.1822.74250663.257000.310802.299601.42290K562PUM2
COX19ENSG00000240230.1275.47410564.41920-1.034906.579405.78330K562PUS1
COX19ENSG00000240230.1263.13310549.87940-1.0633014.0048012.66440K562RBM15
COX19ENSG00000240230.1346.96890249.242700.477202.634801.81600K562RBM22
COX19ENSG00000240230.1571.75160226.767701.3341014.4726012.57920K562RPS19
COX19ENSG00000240230.1428.23400240.706800.831005.438703.96850K562RPS3
COX19ENSG00000240230.1422.59970289.163800.547302.816001.83370K562SF3B1
COX19ENSG00000240230.1337.74600254.766300.406702.031601.41530K562SRSF1
COX19ENSG00000240230.1362.66120248.729300.543903.383702.46560K562TIA1
COX19ENSG00000240230.1279.32990195.324500.516002.851602.03610K562U2AF2
COX19ENSG00000240230.1547.29840417.872300.389203.109102.34900K562UPF1
COX19ENSG00000240230.1634.10980371.841900.7699011.421809.83550K562WDR43
COX19ENSG00000240230.1738.15770563.461100.389502.802001.50090K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COX19 is not available on ENCORE database.





1 RBPs can affect the splicing of COX19 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSCOX19ENSG00000240230.1chr7-1012816101302310128161012928101506310151850.063000.000000.00003longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COX19 is not avaliable on ENCORE database.