ATF6

General Information

Gene Name       : ATF6
Gene ID             : ENSG00000118217.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ATF6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ATF6ENSG00000118217.515.0213.1014.06ENCSR000AEF
HepG2ATF6ENSG00000118217.58.5813.1910.88ENCSR985KAT
K562ATF6ENSG00000118217.515.9917.9316.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ATF6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ATF6 RNA is bound by 27 proteins.  







eCLIP assay for ATF6 is not avaliable on ENCORE database.





27 proteins are bound to ATF6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1161933389161933490+3'-UTR3.4610711.11032K562PUM2
chr1161931000161931051+3'-UTR4.193416.26940K562FAM120A
chr1161931447161931504+3'-UTR3.592369.30182K562UPF1
chr1161928722161928776+3'-UTR3.392364.57444K562TIA1
chr1161930907161931025+3'-UTR4.195476.99270K562IGF2BP1
chr1161930098161930169+3'-UTR4.544754.24698K562IGF2BP1
chr1161928602161928647+3'-UTR3.526883.87469HepG2BCLAF1
chr1161933446161933501+3'-UTR3.338866.13908K562FAM120A
chr1161929091161929183+3'-UTR5.9486414.48846K562UPF1
chr1161933433161933494+3'-UTR3.203125.62891K562UPF1
chr1161930605161930674+3'-UTR3.482325.33418K562FAM120A
chr1161933433161933504+3'-UTR4.845117.13565K562IGF2BP1
chr1161931373161931434+3'-UTR4.3562215.01187K562UPF1
chr1161928429161928497+3'-UTR,CDS4.333864.72754K562YBX3
chr1161929139161929210+3'-UTR3.283766.64080K562FAM120A
chr1161930944161931070+3'-UTR4.365734.19989HepG2UPF1
chr1161736121161736232+5'-UTR,CDS4.2906812.69208HepG2GRSF1
chr1161761961161762040+CDS4.091703.96931HepG2G3BP1
chr1161771992161772059+CDS4.131974.43679K562IGF2BP1
chr1161771841161771883+CDS,intron-Proximal4.179294.29122K562IGF2BP2
chr1161816238161816358+CDS,intron-Proximal5.6412910.71076HepG2BCLAF1
chr1161771883161771962+CDS3.619145.02737K562IGF2BP2
chr1161762092161762118+CDS,intron-Proximal3.377543.57974K562IGF2BP1
chr1161771831161771900+CDS,intron-Proximal3.442314.25142K562BUD13
chr1161789573161789610+CDS,intron-Proximal4.446248.80935HepG2BCLAF1
chr1161882083161882160+CDS,intron-Proximal3.104754.04126K562SND1
chr1161753788161753884+CDS3.377865.55412K562IGF2BP1
chr1161823025161823098+CDS4.379144.07072K562UCHL5
chr1161761224161761326+CDS3.284423.97184HepG2G3BP1
chr1161882085161882123+CDS,intron-Proximal4.026884.51739HepG2BCLAF1
chr1161829993161830068+CDS,intron-Proximal3.420895.13799K562SND1
chr1161789422161789450+CDS,intron-Proximal4.479435.66624K562LIN28B
chr1161771960161772062+CDS3.452944.47362HepG2G3BP1
chr1161833013161833082+CDS3.372785.13799K562SND1
chr1161736217161736286+CDS,intron-Proximal4.973854.48002K562AQR
chr1161816238161816358+CDS,intron-Proximal4.470995.35719HepG2GRWD1
chr1161790914161790955+CDS,intron-Proximal3.580345.97823HepG2BCLAF1
chr1161823016161823092+CDS3.041145.11643K562ZNF622
chr1161789484161789569+CDS4.598434.25741HepG2G3BP1
chr1161748032161748100+CDS,intron-Proximal3.002303.84692K562UCHL5
chr1161816305161816358+CDS3.239355.04943K562ZNF622
chr1161762037161762119+CDS,intron-Proximal3.878118.70187K562ZNF622
chr1161751730161751791+CDS,intron-Proximal4.073443.11282HepG2G3BP1
chr1161789482161789563+CDS3.169416.59678HepG2BCLAF1
chr1161816238161816346+CDS,intron-Proximal3.226555.51367HepG2G3BP1
chr1161833081161833107+CDS,intron-Proximal4.153765.79432HepG2BCLAF1
chr1161829996161830069+CDS,intron-Proximal3.897218.08603HepG2BCLAF1
chr1161823013161823081+CDS,intron-Proximal4.369663.92846K562SND1
chr1161753738161753807+CDS,intron-Proximal3.700715.85504K562SF3B4
chr1161761977161762060+CDS3.112944.72960K562IGF2BP1
chr1161789583161789609+CDS,intron-Proximal3.119915.44868K562ZNF622
chr1161789450161789513+CDS4.0284611.07439K562LIN28B
chr1161789554161789583+CDS3.475847.28841K562ZNF622
chr1161892095161892210+intron-Distal4.148714.17759HepG2QKI
chr1161884436161884540+intron-Distal4.010163.09122HepG2PTBP1
chr1161858733161858866+intron-Distal4.625925.18391K562HNRNPL
chr1161820980161821062+intron-Distal3.167303.12105HepG2HNRNPL
chr1161850408161850501+intron-Distal3.805744.23286HepG2QKI
chr1161885831161885921+intron-Distal4.640084.30178K562PTBP1
chr1161819468161819516+intron-Distal3.809023.39864HepG2SUGP2
chr1161835709161835757+intron-Distal3.498324.52210K562KHSRP
chr1161840402161840474+intron-Distal4.220303.92684K562KHSRP
chr1161884431161884529+intron-Distal4.374823.91475K562PTBP1
chr1161798519161798627+intron-Distal3.112753.75707K562SAFB2
chr1161754811161754920+intron-Distal3.820743.33944K562MATR3
chr1161858725161858735+intron-Distal5.7569632.13527K562NSUN2
chr1161741035161741077+intron-Distal4.9780512.11137K562PTBP1
chr1161740987161741035+intron-Distal4.3120613.29492K562PTBP1
chr1161840664161840738+intron-Distal3.820136.19377K562KHSRP
chr1161858735161858750+intron-Distal5.7569632.13527K562NSUN2
chr1161757562161757675+intron-Distal4.281004.79379K562KHSRP
chr1161840738161840766+intron-Distal4.017777.99418K562KHSRP
chr1161884129161884229+intron-Distal3.767293.06015K562MATR3
chr1161840766161840799+intron-Distal4.848997.66316K562KHSRP
chr1161798999161799067+intron-Distal4.755785.29868K562UCHL5
chr1161751261161751435+intron-Distal3.452744.10408K562KHSRP
chr1161835640161835709+intron-Distal3.093634.56635K562KHSRP
chr1161751465161751535+intron-Distal3.065883.48890K562KHSRP
chr1161751544161751645+intron-Distal,intron-Proximal4.065884.37030K562KHSRP
chr1161740986161741069+intron-Distal3.714825.80375HepG2PTBP1
chr1161858792161858873+intron-Distal3.727453.19026HepG2HNRNPL
chr1161771829161771841+intron-Proximal4.761856.56329K562U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ATF6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ATF6 is not available on ENCORE database.

  • 81 RBPs can affect the levels of ATF6.  








The Knockdown/knockout RNA-Seq assay for ATF6 is not available on ENCORE database.





81 RBPs can affect the gene expression of ATF6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ATF6ENSG00000118217.51461.975201099.444000.411003.722002.48780HepG2AATF
ATF6ENSG00000118217.51237.173501690.11830-0.450103.498502.44320HepG2ABCF1
ATF6ENSG00000118217.51544.823101291.725800.258003.080702.44400HepG2ACO1
ATF6ENSG00000118217.52958.565801995.067700.568405.238504.53580HepG2AKAP1
ATF6ENSG00000118217.52099.079601650.745900.346502.555301.79920HepG2ASCC1
ATF6ENSG00000118217.52099.192901234.548500.7658012.1398011.00650HepG2BOP1
ATF6ENSG00000118217.51841.249101505.175200.290702.706701.94330HepG2CALR
ATF6ENSG00000118217.51067.300501451.52000-0.443602.193701.51800HepG2CNOT7
ATF6ENSG00000118217.51974.412801581.331100.320203.976303.23160HepG2CELF1
ATF6ENSG00000118217.5965.746901194.68090-0.306903.834802.87280HepG2DDX19B
ATF6ENSG00000118217.5966.282801213.41580-0.328602.520801.87080HepG2DDX21
ATF6ENSG00000118217.52710.387701911.112900.504004.844804.03550HepG2DDX3X
ATF6ENSG00000118217.52063.980201641.711400.330102.003801.47080HepG2DDX6
ATF6ENSG00000118217.51040.835101306.71800-0.328203.446602.66790HepG2DNAJC21
ATF6ENSG00000118217.52598.318102021.467400.362106.154505.31800HepG2ETF1
ATF6ENSG00000118217.51431.381901156.169900.308002.399201.33050HepG2FASTKD2
ATF6ENSG00000118217.52697.642401706.627300.660507.003805.83720HepG2FIP1L1
ATF6ENSG00000118217.51209.803801759.73570-0.540605.238804.30770HepG2FXR1
ATF6ENSG00000118217.51530.002801233.254300.311003.992902.83310HepG2HDGF
ATF6ENSG00000118217.5884.187201319.23740-0.577306.703205.76360HepG2HNRNPA1
ATF6ENSG00000118217.51138.777001467.42920-0.365803.057702.33350HepG2HNRNPC
ATF6ENSG00000118217.52000.423101652.992100.275101.950801.35760HepG2HNRNPK
ATF6ENSG00000118217.51200.158901462.71240-0.285402.348301.67970HepG2IGF2BP1
ATF6ENSG00000118217.51211.732001659.28480-0.453503.779003.00030HepG2IGF2BP2
ATF6ENSG00000118217.51197.623801760.35020-0.555705.318904.41600HepG2MAGOH
ATF6ENSG00000118217.51670.274501381.291700.274002.171501.45010HepG2MSI2
ATF6ENSG00000118217.52018.043201442.872100.483909.144107.74760HepG2PARN
ATF6ENSG00000118217.51605.135401315.374900.287103.362902.51730HepG2PRPF4
ATF6ENSG00000118217.51281.355301645.05880-0.360504.533403.87060HepG2PTBP1
ATF6ENSG00000118217.51277.633501609.52970-0.333202.962002.34880HepG2PUF60
ATF6ENSG00000118217.52227.767801708.553300.382708.046507.14490HepG2PUM1
ATF6ENSG00000118217.52671.963901707.326100.6461012.2872010.93270HepG2PUM2
ATF6ENSG00000118217.52100.708001781.604300.237602.196501.62900HepG2QKI
ATF6ENSG00000118217.52512.404901785.871400.492307.496306.17900HepG2RBM15
ATF6ENSG00000118217.52066.009401616.933600.353503.586302.82550HepG2RBM25
ATF6ENSG00000118217.5843.788201241.75310-0.557404.349103.01890HepG2RCC2
ATF6ENSG00000118217.51286.684801830.77890-0.508809.194208.31100HepG2NELFE
ATF6ENSG00000118217.51328.194901705.14650-0.360405.023504.22320HepG2RECQL
ATF6ENSG00000118217.5784.51560972.18130-0.309402.164201.61400HepG2RPS19
ATF6ENSG00000118217.5734.388701410.34600-0.9414013.7352012.04960HepG2RPS2
ATF6ENSG00000118217.5924.134701457.08810-0.656905.176204.08090HepG2RPS3A
ATF6ENSG00000118217.5909.238801298.15670-0.513709.126008.06330HepG2SAFB2
ATF6ENSG00000118217.5924.996601213.53500-0.391703.068402.32600HepG2SF3B1
ATF6ENSG00000118217.51248.945301513.84870-0.277503.873103.13300HepG2SMN1
ATF6ENSG00000118217.52697.021001350.276000.9980010.060108.57570HepG2SNRNP70
ATF6ENSG00000118217.52690.891801908.319700.4957012.1412011.28950HepG2SRFBP1
ATF6ENSG00000118217.51864.637801589.135900.230602.412201.82310HepG2SRSF5
ATF6ENSG00000118217.52331.194101454.390300.6806020.0683018.83090HepG2SRSF9
ATF6ENSG00000118217.5940.484301656.88340-0.8170022.2318021.08390HepG2SSB
ATF6ENSG00000118217.52094.815301606.877600.382505.348804.61140HepG2TAF15
ATF6ENSG00000118217.51943.856401476.466200.396704.612803.54020HepG2TIA1
ATF6ENSG00000118217.5745.811001416.37240-0.9253018.9959017.90210HepG2TIAL1
ATF6ENSG00000118217.51565.922301365.642100.197301.931101.33020HepG2UPF1
ATF6ENSG00000118217.5911.994901318.47580-0.531808.780607.81150HepG2UTP3
ATF6ENSG00000118217.5670.230801018.92410-0.604304.852203.90130HepG2XRN2
ATF6ENSG00000118217.52208.718701501.946700.5563016.1037015.05700HepG2ZNF622
ATF6ENSG00000118217.52508.876603856.66650-0.6203019.1085017.73960K562AGGF1
ATF6ENSG00000118217.53381.588504237.72840-0.325603.222302.14160K562AKAP8
ATF6ENSG00000118217.52228.608804012.99560-0.8485017.6037015.68710K562AKAP8L
ATF6ENSG00000118217.52205.850402664.03370-0.272302.015901.49970K562AQR
ATF6ENSG00000118217.53088.722604210.52170-0.447008.403006.68060K562ATP5C1
ATF6ENSG00000118217.53657.708804318.52540-0.239603.115402.17810K562DKC1
ATF6ENSG00000118217.51213.181601517.45580-0.322902.272101.44530K562EFTUD2
ATF6ENSG00000118217.51152.408801587.74310-0.462303.827202.47200K562FKBP4
ATF6ENSG00000118217.52284.837101735.974600.396202.470801.80890K562G3BP2
ATF6ENSG00000118217.52151.376402919.76410-0.440605.614304.53440K562GRSF1
ATF6ENSG00000118217.51302.763901829.09580-0.489605.867905.03020K562HNRNPC
ATF6ENSG00000118217.51913.964302244.87250-0.230102.235801.43270K562HNRNPU
ATF6ENSG00000118217.53002.752404258.93370-0.504207.210705.72660K562KIF1C
ATF6ENSG00000118217.51191.961501560.32300-0.388502.224001.39720K562KRR1
ATF6ENSG00000118217.53172.802004076.73210-0.361703.822702.48940K562MAK16
ATF6ENSG00000118217.51544.767802104.34620-0.446005.462604.10580K562MATR3
ATF6ENSG00000118217.53656.877104771.06160-0.383705.055103.75080K562MBNL1
ATF6ENSG00000118217.51847.087502278.40760-0.302804.409403.40890K562MTPAP
ATF6ENSG00000118217.52184.531803344.15620-0.614305.543304.14150K562NAA15
ATF6ENSG00000118217.51404.867901800.81280-0.358202.738001.32970K562NUSAP1
ATF6ENSG00000118217.51554.186402221.31570-0.515304.922502.74830K562PKM
ATF6ENSG00000118217.51225.322201639.95670-0.420503.756002.67970K562PSIP1
ATF6ENSG00000118217.52727.331103980.08130-0.545307.001106.18280K562PUS1
ATF6ENSG00000118217.52391.288803877.74870-0.6974017.9416016.40280K562RBM15
ATF6ENSG00000118217.51049.741801496.15470-0.511206.236904.74770K562RCC2
ATF6ENSG00000118217.51067.227701418.32430-0.410303.560502.35620K562SRFBP1
ATF6ENSG00000118217.52492.561502008.266000.311603.199202.44350K562SRSF1
ATF6ENSG00000118217.51573.941202032.57240-0.368903.075302.32790K562TARDBP
ATF6ENSG00000118217.51150.364501577.37530-0.455403.744502.65300K562TIAL1
ATF6ENSG00000118217.52294.478402684.10660-0.226302.931202.19190K562UPF1
ATF6ENSG00000118217.52757.675004035.09360-0.549102.692601.42520K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ATF6 is not available on ENCORE database.





2 RBPs can affect the splicing of ATF6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEATF6ENSG00000118217.5chr1+161829996161830067161823013161823113161832987161833102-0.089000.000000.00000excludedK562AQR
SEATF6ENSG00000118217.5chr1+161790826161790951161789392161789608161816238161816370-0.088000.000730.00936excludedK562AQR
SEATF6ENSG00000118217.5chr1+161771841161772062161761913161762117161789422161789608-0.065000.000200.00313excludedK562AQR
A3SSATF6ENSG00000118217.5chr1+161829996161830034161830011161830034161823013161823113-0.107000.000000.00036shorterK562SF3B4
MXEATF6ENSG00000118217.5chr1+161771841161772062161789392161789608161761913161762117161816238161816370-0.072000.000700.006642includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ATF6 is not avaliable on ENCORE database.